ITC-6102RO, a novel B7-H3 antibody-drug conjugate, exhibits potent therapeutic effects against B7-H3 expressing solid tumors
Shin, Seol Hwa, Ju, Eun Jin, Park, Jin, Ko, Eun Jung, Kwon, Mi Ri, Lee, Hye Won, Son, Ga Won, Park, Yun-Yong, Kim, Yeon Joo, Song, Si Yeol, Lee, Sangkwang, Seo, Beom Seok, Song, Jin-A, Lim, Sangbin, Jung, Doohwan, Kim, Sunyoung, Lee, Hyangsook, Park, Seok Soon, Jeong, Seong-Yun, Choi, Eun Kyung
Published in Cancer cell international (18.08.2023)
Published in Cancer cell international (18.08.2023)
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Aryl Sulfate is a Useful Motif for Conjugating and Releasing Phenolic Molecules: Sulfur Fluorine Exchange Click Chemistry Enables Discovery of Ortho-Hydroxy-Protected Aryl Sulfate Linker
Park, Suho, Kim, Sun Young, Cho, Jongun, Jung, Doohwan, Seo, Donghoon, Lee, Jaeho, Lee, Sangkwang, Yun, Sanghyeon, Lee, Hyangsook, Park, Okku, Seo, Beomseok, Woo, Sung Ho, Park, Tae Kyo
Published in Bioconjugate chemistry (17.07.2019)
Published in Bioconjugate chemistry (17.07.2019)
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Introduction of Para-Hydroxy Benzyl Spacer Greatly Expands the Utility of Ortho-Hydroxy-Protected Aryl Sulfate System: Application to Nonphenolic Payloads
Park, Suho, Kim, Sun Young, Cho, Jongun, Jung, Doohwan, Seo, Donghoon, Lee, Jaeho, Lee, Sangkwang, Yun, Sanghyeon, Lee, Hyangsook, Park, Okku, Seo, Beomseok, Kim, Sena, Seol, Minah, Woo, Sung Ho, Park, Tae Kyo
Published in Bioconjugate chemistry (17.07.2019)
Published in Bioconjugate chemistry (17.07.2019)
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Journal Article
Sulfonate Version of OHPAS Linker Has Two Distinct Pathways of Breakdown: Elimination Route Allows Para-Hydroxy-Protected Benzylsulfonate (PHP-BS) to Serve as an Alternative Self-Immolative Group
Park, Suho, Kim, Sun Young, Cho, Jongun, Jung, Doohwan, Ha, Jihyeon, Seo, Donghoon, Lee, Jaeho, Lee, Sangkwang, Yun, Sanghyeon, Lee, Hyangsook, Park, Okku, Seo, Beomseok, Kim, Sena, Seol, Minah, Song, Jina, Park, Tae Kyo
Published in Bioconjugate chemistry (20.05.2020)
Published in Bioconjugate chemistry (20.05.2020)
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Journal Article
Abstract LB279: The combination therapy with B7-H3 antibody drug conjugates for effective radiation treatment
Son, Gawon, Ju, Eunjin, Park, Jin, Shin, Seolhwa, Ko, Eunjeong, Kwon, Miri, Lee, Hyewon, Seo, Beomseok, Lee, Sangkwang, Park, Seoksoon, Jeong, Seongyun, Song, Siyeol, Choi, Eunkyung
Published in Cancer research (Chicago, Ill.) (05.04.2024)
Published in Cancer research (Chicago, Ill.) (05.04.2024)
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극성기를 갖는 독소를 포함하는 항체 약물 접합체 및 이의 용도
CHOI JIHYE, SEO DONGHOON, JEON CHEOLMIN, LEE HYANG SOOK, YOO JAE DO, LEE SANGKWANG, KIM HYEWON, LEE CHOHEE, HA JIHYEON, JUNG DOOHWAN, SONG JINA, JEONG MYEONGHWA, KIM YA GOB, PARK TAEKYO, KIM SUNYOUNG, YANG EUN HYE, SEO BEOMSEOK, KIM SENA, REW YOSUP
Year of Publication 22.08.2024
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Year of Publication 22.08.2024
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분자 접합과 관련된 조성물 및 방법
SEO DONGHOON, LEE HYANG SOOK, SEOL MINAH, LEE SANGKWANG, HA JIHYEON, JUNG DOOHWAN, SONG JINA, YUN SANGHYEON, PARK SUHO, PARK TAEKYO, KIM SUNYOUNG, PARK OKKU, SEO BEOMSEOK, KIM SENA
Year of Publication 03.08.2022
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Year of Publication 03.08.2022
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항-B7-H3 항체를 포함하는 항체-약물 접합체
PARK JAE EUN, LEE EUNJIN, SEO DONGHOON, LEE HYANG SOOK, LEE MINJU, LEE SANGKWANG, JUNG DOOHWAN, PARK YOUNG WOO, YUN SANGHYEON, PARK SUHO, KIM SUNYOUNG, PARK OKKU, WOO SUNG HO, KIM SENA, REW YOSUP, LEE JAEHO, KO YUNJUNG, CHO JONGUN, SEOL MINAH, SONG YOUNGJA, HA JIHYEON, SONG JINA, LEE HYUN MI, LEE HYUN JU, SHIM EUN YOUNG, PARK TAEKYO, SEO BEOMSEOK
Year of Publication 02.03.2023
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Year of Publication 02.03.2023
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절단가능 링커를 포함하는 화합물 및 이의 용도
LEE JAEHO, CHO JONGUN, SEO DONGHOON, LEE HYANG SOOK, SEOL MINAH, LEE SANGKWANG, HA JIHYEON, JUNG DOOHWAN, SONG JINA, YUN SANGHYEON, PARK SUHO, PARK TAEKYO, WOO SUNG HO, KIM SUNYOUNG, PARK OKKU, SEO BEOMSEOK, KIM SENA
Year of Publication 12.08.2021
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Year of Publication 12.08.2021
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절단가능 링커를 포함하는 화합물 및 이의 용도
LEE JAEHO, CHO JONGUN, SEO DONGHOON, LEE HYANG SOOK, SEOL MINAH, LEE SANGKWANG, HA JIHYEON, JUNG DOOHWAN, SONG JINA, YUN SANGHYEON, PARK SUHO, PARK TAEKYO, WOO SUNG HO, KIM SUNYOUNG, PARK OKKU, SEO BEOMSEOK, KIM SENA
Year of Publication 12.08.2021
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Year of Publication 12.08.2021
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융합된 헤테로시클릭 벤조디아제핀 유도체 및 그의 용도
LEE JAEHO, CHO JONGUN, SEO DONGHOON, LEE HYANG SOOK, SEOL MINAH, LEE SANGKWANG, JUNG DOOHWAN, YUN SANGHYEON, PARK SUHO, PARK TAEKYO, WOO SUNG HO, KIM SUNYOUNG, PARK OKKU, SEO BEOMSEOK, KIM SENA
Year of Publication 09.06.2021
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Year of Publication 09.06.2021
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신규한 벤조다이아제핀 유도체 및 그 용도
LEE JAEHO, CHO JONGUN, SEO DONGHOON, LEE HYANG SOOK, SEOL MINAH, LEE SANGKWANG, JUNG DOOHWAN, YUN SANGHYEON, PARK SUHO, PARK TAEKYO, WOO SUNG HO, KIM SUNYOUNG, PARK OKKU, SEO BEOMSEOK, KIM SENA
Year of Publication 12.01.2021
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Year of Publication 12.01.2021
Patent
절단성 링커를 포함하는 화합물 및 이들의 용도
LEE JAEHO, CHO JONGUN, SEO DONGHOON, LEE HYANG SOOK, LEE SANGKWANG, JUNG DOOHWAN, YUN SANGHYEON, PARK SUHO, PARK TAEKYO, WOO SUNG HO, KIM SUNYOUNG, PARK OKKU, SEO BEOMSEOK
Year of Publication 12.03.2020
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Year of Publication 12.03.2020
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Compounds comprising cleavable linker and uses thereof
CHO, Jongun, LEE, Jaeho, PARK, Taekyo, LEE, Sangkwang, KIM, Sunyoung, JUNG, Doohwan, SEO, Donghoon, PARK, Suho, PARK, Okku, LEE, Hyang Sook, WOO, Sung Ho, YUN, Sanghyeon, SEO, Beomseok
Year of Publication 18.04.2024
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Year of Publication 18.04.2024
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COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF
Jung, Doohwan, Seo, Beomseok, Seo, Donghoon, Lee, Hyang Sook, Kim, Sunyoung, Cho, Jongun, Park, Taekyo, Yun, Sanghyeon, Woo, Sung Ho, Park, Suho, Park, Okku, Lee, Sangkwang, Lee, Jaeho
Year of Publication 21.12.2023
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Year of Publication 21.12.2023
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Compounds comprising cleavable linker and uses thereof
CHO, Jongun, LEE, Jaeho, PARK, Taekyo, LEE, Sangkwang, KIM, Sunyoung, JUNG, Doohwan, SEO, Donghoon, PARK, Suho, PARK, Okku, LEE, Hyang Sook, WOO, Sung Ho, YUN, Sanghyeon, SEO, Beomseok
Year of Publication 05.10.2023
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Year of Publication 05.10.2023
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Compounds comprising cleavable linker and uses thereof
Jung, Doohwan, Seo, Beomseok, Seo, Donghoon, Lee, Hyang Sook, Kim, Sunyoung, Cho, Jongun, Park, Taekyo, Yun, Sanghyeon, Woo, Sung Ho, Park, Suho, Park, Okku, Lee, Sangkwang, Lee, Jaeho
Year of Publication 12.09.2023
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Year of Publication 12.09.2023
Patent
Compounds comprising cleavable linker and uses thereof
CHO, Jongun, LEE, Jaeho, PARK, Taekyo, LEE, Sangkwang, KIM, Sunyoung, JUNG, Doohwan, SEO, Donghoon, PARK, Suho, PARK, Okku, LEE, Hyang Sook, WOO, Sung Ho, YUN, Sanghyeon, SEO, Beomseok
Year of Publication 07.09.2023
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Year of Publication 07.09.2023
Patent
Compounds comprising cleavable linker and uses thereof
CHO, Jongun, LEE, Jaeho, PARK, Taekyo, LEE, Sangkwang, KIM, Sunyoung, JUNG, Doohwan, SEO, Donghoon, PARK, Suho, PARK, Okku, LEE, Hyang Sook, WOO, Sung Ho, YUN, Sanghyeon, SEO, Beomseok
Year of Publication 25.05.2023
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Year of Publication 25.05.2023
Patent