Hypoxia-induced epigenetic modifications are associated with cardiac tissue fibrosis and the development of a myofibroblast-like phenotype
Watson, Chris J, Collier, Patrick, Tea, Isaac, Neary, Roisin, Watson, Jenny A, Robinson, Claire, Phelan, Dermot, Ledwidge, Mark T, McDonald, Kenneth M, McCann, Amanda, Sharaf, Osama, Baugh, John A
Published in Human molecular genetics (15.04.2014)
Published in Human molecular genetics (15.04.2014)
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Journal Article
MicroRNA signatures differentiate preserved from reduced ejection fraction heart failure
Watson, Chris J., Gupta, Shashi K., O'Connell, Eoin, Thum, Sabrina, Glezeva, Nadezhda, Fendrich, Jasmin, Gallagher, Joe, Ledwidge, Mark, Grote-Levi, Lea, McDonald, Kenneth, Thum, Thomas
Published in European journal of heart failure (01.04.2015)
Published in European journal of heart failure (01.04.2015)
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Journal Article
Can emerging biomarkers of myocardial remodelling identify asymptomatic hypertensive patients at risk for diastolic dysfunction and diastolic heart failure?
Collier, Patrick, Watson, Chris J., Voon, Victor, Phelan, Dermot, Jan, Aftab, Mak, George, Martos, Ramon, Baugh, John A., Ledwidge, Mark T., McDonald, Kenneth M.
Published in European journal of heart failure (01.10.2011)
Published in European journal of heart failure (01.10.2011)
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Journal Article
Exaggerated Inflammation and Monocytosis Associate With Diastolic Dysfunction in Heart Failure With Preserved Ejection Fraction: Evidence of M2 Macrophage Activation in Disease Pathogenesis
Glezeva, Nadezhda, PhD, Voon, Victor, MD, Watson, Chris, PhD, Horgan, Stephen, MD, PhD, McDonald, Kenneth, MD, Ledwidge, Mark, PhD, Baugh, John, PhD
Published in Journal of cardiac failure (01.02.2015)
Published in Journal of cardiac failure (01.02.2015)
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Journal Article
Epigenetic Therapy for the Treatment of Hypertension-Induced Cardiac Hypertrophy and Fibrosis
Watson, Chris J., Horgan, Stephen, Neary, Roisin, Glezeva, Nadezhda, Tea, Isaac, Corrigan, Niamh, McDonald, Ken, Ledwidge, Mark, Baugh, John
Published in Journal of cardiovascular pharmacology and therapeutics (01.01.2016)
Published in Journal of cardiovascular pharmacology and therapeutics (01.01.2016)
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Journal Article
FKBPL is associated with metabolic parameters and is a novel determinant of cardiovascular disease
Januszewski, Andrzej S., Watson, Chris J., O’Neill, Vikki, McDonald, Kenneth, Ledwidge, Mark, Robson, Tracy, Jenkins, Alicia J., Keech, Anthony C., McClements, Lana
Published in Scientific reports (10.12.2020)
Published in Scientific reports (10.12.2020)
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Journal Article
Biomarker profiling for risk of future heart failure (HFpEF) development
Watson, Chris J, Gallagher, Joe, Wilkinson, Mark, Russell-Hallinan, Adam, Tea, Isaac, James, Stephanie, O'Reilly, James, O'Connell, Eoin, Zhou, Shuaiwei, Ledwidge, Mark, McDonald, Ken
Published in Journal of translational medicine (09.02.2021)
Published in Journal of translational medicine (09.02.2021)
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Journal Article
Targeted DNA Methylation Profiling of Human Cardiac Tissue Reveals Novel Epigenetic Traits and Gene Deregulation Across Different Heart Failure Patient Subtypes
Glezeva, Nadezhda, Moran, Bruce, Collier, Patrick, Moravec, Christine S, Phelan, Dermot, Donnellan, Eoin, Russell-Hallinan, Adam, O'Connor, Darran P, Gallagher, William M, Gallagher, Joe, McDonald, Kenneth, Ledwidge, Mark, Baugh, John, Das, Sudipto, Watson, Chris J
Published in Circulation. Heart failure (01.03.2019)
Published in Circulation. Heart failure (01.03.2019)
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Journal Article
Cost-effectiveness of natriuretic peptide-based screening and collaborative care: a report from the STOP-HF (St Vincent's Screening TO Prevent Heart Failure) study
Ledwidge, Mark T., O'Connell, Eoin, Gallagher, Joseph, Tilson, Lesley, James, Stephanie, Voon, Victor, Bermingham, Margaret, Tallon, Elaine, Watson, Chris, O'Hanlon, Rory, Barry, Michael, McDonald, Kenneth
Published in European journal of heart failure (01.07.2015)
Published in European journal of heart failure (01.07.2015)
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Journal Article
Natural History of Markers of Collagen Turnover in Patients With Early Diastolic Dysfunction and Impact of Eplerenone
Mak, George J., MD, Ledwidge, Mark T., PhD, Watson, Chris J., PhD, Phelan, Dermot M., MD, Dawkins, Ian R., DPhil, Murphy, Niamh F., MD, PhD, Patle, Anil K., BTech, Baugh, John A., PhD, McDonald, Kenneth M., MD
Published in Journal of the American College of Cardiology (27.10.2009)
Published in Journal of the American College of Cardiology (27.10.2009)
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Journal Article
Aetiology and severity of childhood pneumonia in primary care in Malawi: a cohort study
Gallagher, Joe, Chisale, Master, Das, Sudipto, Drew, Richard J, Glezeva, Nadezhda, Wildes, Dermot Michael, De Gascun, Cillian, Wu, Tsung-Shu Joseph, Ledwidge, Mark T, Watson, Chris
Published in BMJ open (29.07.2021)
Published in BMJ open (29.07.2021)
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Journal Article
Comparison of longitudinal change in sST2 vs BNP to predict major adverse cardiovascular events in asymptomatic patients in the community
Watson, Chris J., Tea, Isaac, O'Connell, Eoin, Glezeva, Nadezhda, Zhou, Shuaiwei, James, Stephanie, Gallagher, Joe, Snider, James, Januzzi, James L., Ledwidge, Mark T., McDonald, Ken M.
Published in Journal of cellular and molecular medicine (01.06.2020)
Published in Journal of cellular and molecular medicine (01.06.2020)
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Journal Article
Atrial Tissue Pro-Fibrotic M2 Macrophage Marker CD163+, Gene Expression of Procollagen and B-Type Natriuretic Peptide
Watson, Chris J, Glezeva, Nadezhda, Horgan, Stephen, Gallagher, Joe, Phelan, Dermot, McDonald, Ken, Tolan, Michael, Baugh, John, Collier, Patrick, Ledwidge, Mark
Published in Journal of the American Heart Association (02.06.2020)
Published in Journal of the American Heart Association (02.06.2020)
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Journal Article
A systematic review of clinical prediction rules for the diagnosis of chronic heart failure
Gallagher, Joe, McCormack, Darren, Zhou, Shuaiwei, Ryan, Fiona, Watson, Chris, McDonald, Kenneth, Ledwidge, Mark T.
Published in ESC Heart Failure (01.06.2019)
Published in ESC Heart Failure (01.06.2019)
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Journal Article
Modest elevation in BNP in asymptomatic hypertensive patients reflects sub-clinical cardiac remodeling, inflammation and extracellular matrix changes
Phelan, Dermot, Watson, Chris, Martos, Ramon, Collier, Patrick, Patle, Anil, Donnelly, Seamas, Ledwidge, Mark, Baugh, John, McDonald, Ken
Published in PloS one (12.11.2012)
Published in PloS one (12.11.2012)
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Journal Article
Investigation of association of genetic variant rs3918242 of matrix metalloproteinase-9 with hypertension, myocardial infarction and progression of ventricular dysfunction in Irish Caucasian patients with diabetes: a report from the STOP-HF follow-up programme
Watson, Chris, Spiers, J Paul, Waterstone, Max, Russell-Hallinan, Adam, Gallagher, Joseph, McDonald, Kenneth, Ryan, Cristin, Gilmer, John, Ledwidge, Mark
Published in BMC cardiovascular disorders (12.02.2021)
Published in BMC cardiovascular disorders (12.02.2021)
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Journal Article
Heart failure virtual consultation: caters for frailer, multimorbid and remote patients
Wong, Bethany, McCambridge, Joseph, Barrett, Matthew, Ledwidge, Mark, McCudden, Lisa, Fawsitt, Ronan, Gallagher, Joseph J, McDonald, Kenneth
Published in Open heart (01.08.2023)
Published in Open heart (01.08.2023)
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