Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist
Sun, Bingfa, Feng, Dan, Chu, Matthew Ling-Hon, Fish, Inbar, Lovera, Silvia, Sands, Zara A, Kelm, Sebastian, Valade, Anne, Wood, Martyn, Ceska, Tom, Kobilka, Tong Sun, Lebon, Florence, Kobilka, Brian K
Published in Nature communications (03.06.2021)
Published in Nature communications (03.06.2021)
Get full text
Journal Article
The potential for opportunistic identification of vertebral fractures in patients undergoing a CT scan as part of daily clinical practice: Descriptive study using registry data
Skjødt, Michael Kriegbaum, Nicolaes, Joeri, Smith, Christopher Dyer, Banefelt, Jonas, Lebon, Florence, Libanati, Cesar, Olsen, Kim Rose, Cooper, Cyrus, Abrahamsen, Bo
Published in Bone Reports (01.10.2020)
Published in Bone Reports (01.10.2020)
Get full text
Journal Article
Crystal structure of the adenosine A2A receptor bound to an antagonist reveals a potential allosteric pocket
Sun, Bingfa, Bachhawat, Priti, Chu, Matthew Ling-Hon, Wood, Martyn, Ceska, Tom, Sands, Zara A., Mercier, Joel, Lebon, Florence, Kobilka, Tong Sun, Kobilka, Brian K.
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2017)
Get full text
Journal Article
Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A
Benoit, Roger M, Frey, Daniel, Hilbert, Manuel, Kevenaar, Josta T, Wieser, Mara M, Stirnimann, Christian U, McMillan, David, Ceska, Tom, Lebon, Florence, Jaussi, Rolf, Steinmetz, Michel O, Schertler, Gebhard F X, Hoogenraad, Casper C, Capitani, Guido, Kammerer, Richard A
Published in Nature (London) (02.01.2014)
Published in Nature (London) (02.01.2014)
Get full text
Journal Article
Crystal structure of the adenosine A 2A receptor bound to an antagonist reveals a potential allosteric pocket
Sun, Bingfa, Bachhawat, Priti, Chu, Matthew Ling-Hon, Wood, Martyn, Ceska, Tom, Sands, Zara A, Mercier, Joel, Lebon, Florence, Kobilka, Tong Sun, Kobilka, Brian K
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2017)
Get full text
Journal Article
Combining modelling and mutagenesis studies of synaptic vesicle protein 2A to identify a series of residues involved in racetam binding
Shi, Jiye, Anderson, Dina, Lynch, Berkley A, Castaigne, Jean-Gabriel, Foerch, Patrik, Lebon, Florence
Published in Biochemical Society transactions (01.10.2011)
Published in Biochemical Society transactions (01.10.2011)
Get more information
Journal Article
Development of Dimethyl Sulfoxide Solubility Models Using 163 000 Molecules: Using a Domain Applicability Metric to Select More Reliable Predictions
Tetko, Igor V, Novotarskyi, Sergii, Sushko, Iurii, Ivanov, Vladimir, Petrenko, Alexander E, Dieden, Reiner, Lebon, Florence, Mathieu, Benoit
Published in Journal of chemical information and modeling (26.08.2013)
Published in Journal of chemical information and modeling (26.08.2013)
Get full text
Journal Article
Towards a KCC2 blocker pharmacophore model
Lebon, Florence, Pégurier, Cécile, Ledecq, Marie, Mathieu, Benoit, Bosman, Nathalie, Frycia, Anne, Lengelé, Sébastien, Dhurke, Kashinath, Kanduluru, Ananda Kumar, Meunier, Stéphane, Wagner, Alain, Wolff, Christian, Provins, Laurent
Published in Bioorganic & medicinal chemistry letters (15.06.2012)
Published in Bioorganic & medicinal chemistry letters (15.06.2012)
Get full text
Journal Article
4-benzyl-1H-imidazoles with oxazoline termini as histamine H-3 receptor agonists
Wijtmans, Maikel, Celanire, Sylvain, Snip, Erwin, Gillard, Michel R., Gelens, Edith, Collart, Philippe P., Venhuis, Bastiaan J., Christophe, Bernard, Hulscher, Saskia, van der Goot, Henk, Lebon, Florence, Timmerman, Henk, Bakker, Remko A., Lallemand, Benedicte I. L. F., Leurs, Rob, Talaga, Patrice E., de Esch, Iwan J. P.
Published in Journal of medicinal chemistry (22.05.2008)
Published in Journal of medicinal chemistry (22.05.2008)
Get full text
Journal Article
First dual M3 antagonists-PDE4 inhibitors : Synthesis and SAR of 4,6-diaminopyrimidine derivatives
PROVINS, Laurent, CHRISTOPHE, Bernard, DANHAIVE, Pierre, DULIEU, Jacques, DURIEU, Véronique, GILLARD, Michel, LEBON, Florence, LENGELE, Sébastien, QUERE, Luc, VAN KEULEN, Berendjan
Published in Bioorganic & medicinal chemistry letters (01.04.2006)
Published in Bioorganic & medicinal chemistry letters (01.04.2006)
Get full text
Journal Article
Modeling of Copper(II) Complexes with the SIBFA Polarizable Molecular Mechanics Procedure. Application to a New Class of HIV-1 Protease Inhibitors
Ledecq, Marie, Lebon, Florence, Durant, François, Giessner-Prettre, Claude, Marquez, Antonio, Gresh, Nohad
Published in The journal of physical chemistry. B (25.09.2003)
Published in The journal of physical chemistry. B (25.09.2003)
Get full text
Journal Article
4-Benzyl-1H-imidazoles with Oxazoline Termini as Histamine H3 Receptor Agonists
Wijtmans, Maikel, Celanire, Sylvain, Snip, Erwin, Gillard, Michel R, Gelens, Edith, Collart, Philippe P, Venhuis, Bastiaan J, Christophe, Bernard, Hulscher, Saskia, Goot, Henk van der, Lebon, Florence, Timmerman, Henk, Bakker, Remko A, Lallemand, Bénédicte I. L. F, Leurs, Rob, Talaga, Patrice E, Esch, Iwan J. P. de
Published in Journal of medicinal chemistry (22.05.2008)
Published in Journal of medicinal chemistry (22.05.2008)
Get full text
Journal Article
First dual M 3 antagonists-PDE4 inhibitors: Synthesis and SAR of 4,6-diaminopyrimidine derivatives
Provins, Laurent, Christophe, Bernard, Danhaive, Pierre, Dulieu, Jacques, Durieu, Véronique, Gillard, Michel, Lebon, Florence, Lengelé, Sébastien, Quéré, Luc, van Keulen, BerendJan
Published in Bioorganic & medicinal chemistry letters (01.04.2006)
Published in Bioorganic & medicinal chemistry letters (01.04.2006)
Get full text
Journal Article
Metal-organic compounds: a new approach for drug discovery: N1-(4-methyl-2-pyridyl)-2,3,6-trimethoxybenzamide copper(II) complex as an inhibitor of human immunodeficiency virus 1 protease
Lebon, Florence, Boggetto, Nicole, Ledecq, Marie, Durant, François, Benatallah, Zohra, Sicsic, Sames, Lapouyade, René, Kahn, Olivier, Mouithys-Mickalad, Ange, Deby-Dupont, Ginette, Reboud-Ravaux, Michèle
Published in Biochemical pharmacology (15.05.2002)
Published in Biochemical pharmacology (15.05.2002)
Get full text
Journal Article
Discovery of a New Class of Non‐imidazole Oxazoline‐Based Histamine H 3 Receptor (H 3 R) Inverse Agonists
Célanire, Sylvain, Wijtmans, Maikel, Christophe, Bernard, Collart, Philippe, de Esch, Iwan, Dassesse, Donald, Delaunoy, Christel, Denonne, Frédéric, Durieu, Véronique, Gelens, Edith, Gillard, Michel, Lallemand, Bénédicte, Lamberty, Yves, Lebon, Florence, Nicolas, Jean‐Marie, Quéré, Luc, Snip, Erwin, Vanbellinghen, Alain, Van houtvin, Nathalie, Verbois, Valérie, Timmerman, Henk, Talaga, Patrice, Leurs, Rob, Provins, Laurent
Published in ChemMedChem (06.07.2009)
Published in ChemMedChem (06.07.2009)
Get full text
Journal Article
4-Benzyl-1 H -imidazoles with Oxazoline Termini as Histamine H 3 Receptor Agonists
Wijtmans, Maikel, Celanire, Sylvain, Snip, Erwin, Gillard, Michel R., Gelens, Edith, Collart, Philippe P., Venhuis, Bastiaan J., Christophe, Bernard, Hulscher, Saskia, Goot, Henk van der, Lebon, Florence, Timmerman, Henk, Bakker, Remko A., Lallemand, Bénédicte I. L. F., Leurs, Rob, Talaga, Patrice E., Esch, Iwan J. P. de
Published in Journal of medicinal chemistry (01.05.2008)
Published in Journal of medicinal chemistry (01.05.2008)
Get full text
Journal Article
4-Benzyl-lH-imidazoles with Oxazoline Termini as Histamine H3 Receptor Agonists
WIJTMANS, Maikel, CELANIRE, Sylvain, LEBON, Florence, TIMMERMAN, Henk, BAKKER, Remko A, LALLEMAND, Bénédicte I. L. F, LEURS, Rob, TALAGA, Patrice E, DE ESCH, Iwan J. P, SNIP, Erwin, GILLARD, Michel R, GELENS, Edith, COLLART, Philippe P, VENHUIS, Bastiaan J, CHRISTOPHE, Bernard, HULSCHER, Saskia, VAN DER GOOT, Henk
Published in Journal of medicinal chemistry (2008)
Get full text
Published in Journal of medicinal chemistry (2008)
Journal Article
First dual M sub(3) antagonists-PDE4 inhibitors: Synthesis and SAR of 4,6- diaminopyrimidine derivatives
Provins, Laurent, Christophe, Bernard, Danhaive, Pierre, Dulieu, Jacques, Durieu, Veronique, Gillard, Michel, Lebon, Florence, Lengele, Sebastien, Quere, Luc, Van Keulen, BerendJan
Published in Bioorganic & medicinal chemistry letters (01.04.2006)
Published in Bioorganic & medicinal chemistry letters (01.04.2006)
Get full text
Journal Article
Discovery of a New Class of Non-imidazole Oxazoline-Based Histamine H3 Receptor (H3R) Inverse Agonists
Célanire, Sylvain, Wijtmans, Maikel, Christophe, Bernard, Collart, Philippe, de Esch, Iwan, Dassesse, Donald, Delaunoy, Christel, Denonne, Frédéric, Durieu, Véronique, Gelens, Edith, Gillard, Michel, Lallemand, Bénédicte, Lamberty, Yves, Lebon, Florence, Nicolas, Jean-Marie, Quéré, Luc, Snip, Erwin, Vanbellinghen, Alain, Van houtvin, Nathalie, Verbois, Valérie, Timmerman, Henk, Talaga, Patrice, Leurs, Rob, Provins, Laurent
Published in ChemMedChem (06.07.2009)
Published in ChemMedChem (06.07.2009)
Get full text
Journal Article