Hippo pathway deficiency reverses systolic heart failure after infarction
Leach, John P., Heallen, Todd, Zhang, Min, Rahmani, Mahdis, Morikawa, Yuka, Hill, Matthew C., Segura, Ana, Willerson, James T., Martin, James F.
Published in Nature (London) (12.10.2017)
Published in Nature (London) (12.10.2017)
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Journal Article
A RNA-DNA Hybrid Aptamer for Nanoparticle-Based Prostate Tumor Targeted Drug Delivery
Leach, John C, Wang, Andrew, Ye, Kaiming, Jin, Sha
Published in International journal of molecular sciences (14.03.2016)
Published in International journal of molecular sciences (14.03.2016)
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Journal Article
Dystrophin–glycoprotein complex sequesters Yap to inhibit cardiomyocyte proliferation
Morikawa, Yuka, Heallen, Todd, Leach, John, Xiao, Yang, Martin, James F.
Published in Nature (London) (13.07.2017)
Published in Nature (London) (13.07.2017)
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Journal Article
YAP Partially Reprograms Chromatin Accessibility to Directly Induce Adult Cardiogenesis In Vivo
Monroe, Tanner O., Hill, Matthew C., Morikawa, Yuka, Leach, John P., Heallen, Todd, Cao, Shuyi, Krijger, Peter H.L., de Laat, Wouter, Wehrens, Xander H.T., Rodney, George G., Martin, James F.
Published in Developmental cell (25.03.2019)
Published in Developmental cell (25.03.2019)
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Journal Article
Defining the role of pulmonary endothelial cell heterogeneity in the response to acute lung injury
Niethamer, Terren K, Stabler, Collin T, Leach, John P, Zepp, Jarod A, Morley, Michael P, Babu, Apoorva, Zhou, Su, Morrisey, Edward E
Published in eLife (24.02.2020)
Published in eLife (24.02.2020)
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Journal Article
Gene therapy knockdown of Hippo signaling induces cardiomyocyte renewal in pigs after myocardial infarction
Liu, Shijie, Li, Ke, Wagner Florencio, Leonardo, Tang, Li, Heallen, Todd R, Leach, John P, Wang, Yidan, Grisanti, Francisco, Willerson, James T, Perin, Emerson C, Zhang, Sui, Martin, James F
Published in Science translational medicine (30.06.2021)
Published in Science translational medicine (30.06.2021)
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Journal Article
Genomic, epigenomic, and biophysical cues controlling the emergence of the lung alveolus
Zepp, Jarod A, Morley, Michael P, Loebel, Claudia, Kremp, Madison M, Chaudhry, Fatima N, Basil, Maria C, Leach, John P, Liberti, Derek C, Niethamer, Terren K, Ying, Yun, Jayachandran, Sowmya, Babu, Apoorva, Zhou, Su, Frank, David B, Burdick, Jason A, Morrisey, Edward E
Published in Science (American Association for the Advancement of Science) (12.03.2021)
Published in Science (American Association for the Advancement of Science) (12.03.2021)
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Journal Article
The extracellular matrix protein agrin promotes heart regeneration in mice
Bassat, Elad, Mutlak, Yara Eid, Genzelinakh, Alex, Shadrin, Ilya Y., Baruch Umansky, Kfir, Yifa, Oren, Kain, David, Rajchman, Dana, Leach, John, Riabov Bassat, Daria, Udi, Yael, Sarig, Rachel, Sagi, Irit, Martin, James F., Bursac, Nenad, Cohen, Shenhav, Tzahor, Eldad
Published in Nature (London) (13.07.2017)
Published in Nature (London) (13.07.2017)
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Journal Article
Age-dependent alveolar epithelial plasticity orchestrates lung homeostasis and regeneration
Penkala, Ian J., Liberti, Derek C., Pankin, Joshua, Sivakumar, Aravind, Kremp, Madison M., Jayachandran, Sowmya, Katzen, Jeremy, Leach, John P., Windmueller, Rebecca, Stolz, Katharine, Morley, Michael P., Babu, Apoorva, Zhou, Su, Frank, David B., Morrisey, Edward E.
Published in Cell stem cell (07.10.2021)
Published in Cell stem cell (07.10.2021)
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Journal Article
Hippo signaling impedes adult heart regeneration
Heallen, Todd, Morikawa, Yuka, Leach, John, Tao, Ge, Willerson, James T, Johnson, Randy L, Martin, James F
Published in Development (Cambridge) (01.12.2013)
Published in Development (Cambridge) (01.12.2013)
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Journal Article
Gene Therapy Knockdown of Hippo Signaling Resolves Arrhythmic Events in Pigs After Myocardial Infarction
Zhang, Sui, Liu, Shijie, Leach, John P, Li, Ke, Perin, Emerson C, Martin, James F
Published in Circulation (New York, N.Y.) (15.11.2022)
Published in Circulation (New York, N.Y.) (15.11.2022)
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Journal Article
Direct Comparison of Mononucleated and Binucleated Cardiomyocytes Reveals Molecular Mechanisms Underlying Distinct Proliferative Competencies
Windmueller, Rebecca, Leach, John P., Babu, Apoorva, Zhou, Su, Morley, Michael P., Wakabayashi, Aoi, Petrenko, Nataliya B., Viatour, Patrick, Morrisey, Edward E.
Published in Cell reports (Cambridge) (03.03.2020)
Published in Cell reports (Cambridge) (03.03.2020)
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Journal Article
Alcohol and drugs in epilepsy: Pathophysiology, presentation, possibilities, and prevention
Leach, John Paul, Mohanraj, Rajiv, Borland, William
Published in Epilepsia (Copenhagen) (01.09.2012)
Published in Epilepsia (Copenhagen) (01.09.2012)
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Journal Article
Conference Proceeding
Low serum magnesium and 1‐year mortality in alcohol withdrawal syndrome
Maguire, Donogh, Ross, David P., Talwar, Dinesh, Forrest, Ewan, Naz Abbasi, Hina, Leach, John‐Paul, Woods, Marylynne, Zhu, Luke Y., Dickson, Scott, Kwok, Tong, Waterson, Isla, Benson, George, Scally, Benjamin, Young, David, McMillan, Donald C.
Published in European journal of clinical investigation (01.09.2019)
Published in European journal of clinical investigation (01.09.2019)
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Journal Article
Enhancing departmental teaching in the digital age: as easy as 1-3-5
Fenech, Valentina, Martin, Sarah-Jane, Leach, John-Paul
Published in Practical neurology (01.10.2023)
Published in Practical neurology (01.10.2023)
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Journal Article
Long-range Pitx2c enhancer–promoter interactions prevent predisposition to atrial fibrillation
Zhang, Min, Hill, Matthew C., Kadow, Zachary A., Suh, Ji Ho, Tucker, Nathan R., Hall, Amelia W., Tran, Tien T., Swinton, Paul S., Leach, John P., Margulies, Kenneth B., Ellinor, Patrick T., Li, Na, Martin, James F.
Published in Proceedings of the National Academy of Sciences - PNAS (05.11.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (05.11.2019)
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Journal Article
Alcohol and the central nervous system
Wolfe, Maytal, Menon, Arun, Oto, Maria, Fullerton, Natasha E, Leach, John-Paul
Published in Practical neurology (01.08.2023)
Published in Practical neurology (01.08.2023)
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Journal Article
Temporal and spatial staging of lung alveolar regeneration is determined by the grainyhead transcription factor Tfcp2l1
Cardenas-Diaz, Fabian L., Liberti, Derek C., Leach, John P., Babu, Apoorva, Barasch, Jonathan, Shen, Tian, Diaz-Miranda, Maria A., Zhou, Su, Ying, Yun, Callaway, Danielle A., Morley, Michael P., Morrisey, Edward E.
Published in Cell reports (Cambridge) (30.05.2023)
Published in Cell reports (Cambridge) (30.05.2023)
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Journal Article