Type 9 secretion system structures reveal a new protein transport mechanism
Lauber, Frédéric, Deme, Justin C., Lea, Susan M., Berks, Ben C.
Published in Nature (London) (01.12.2018)
Published in Nature (London) (01.12.2018)
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Journal Article
Structure of the core of the type III secretion system export apparatus
Kuhlen, Lucas, Abrusci, Patrizia, Johnson, Steven, Gault, Joseph, Deme, Justin, Caesar, Joseph, Dietsche, Tobias, Mebrhatu, Mehari Tesfazgi, Ganief, Tariq, Macek, Boris, Wagner, Samuel, Robinson, Carol V., Lea, Susan M.
Published in Nature structural & molecular biology (01.07.2018)
Published in Nature structural & molecular biology (01.07.2018)
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Journal Article
Nonameric structures of the cytoplasmic domain of FlhA and SctV in the context of the full-length protein
Kuhlen, Lucas, Johnson, Steven, Cao, Jerry, Deme, Justin C, Lea, Susan M
Published in PloS one (18.06.2021)
Published in PloS one (18.06.2021)
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Journal Article
The Centrosome-Specific Phosphorylation of Cnn by Polo/Plk1 Drives Cnn Scaffold Assembly and Centrosome Maturation
Conduit, Paul T., Feng, Zhe, Richens, Jennifer H., Baumbach, Janina, Wainman, Alan, Bakshi, Suruchi D., Dobbelaere, Jeroen, Johnson, Steven, Lea, Susan M., Raff, Jordan W.
Published in Developmental cell (31.03.2014)
Published in Developmental cell (31.03.2014)
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Journal Article
Mechanism of lipid droplet formation by the yeast Sei1/Ldb16 Seipin complex
Klug, Yoel A., Deme, Justin C., Corey, Robin A., Renne, Mike F., Stansfeld, Phillip J., Lea, Susan M., Carvalho, Pedro
Published in Nature communications (08.10.2021)
Published in Nature communications (08.10.2021)
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Journal Article
Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM
Ding, Jienyu, Deme, Justin C, Stagno, Jason R, Yu, Ping, Lea, Susan M, Wang, Yun-Xing
Published in Nucleic acids research (13.10.2023)
Published in Nucleic acids research (13.10.2023)
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Journal Article
Structural Basis for Mitotic Centrosome Assembly in Flies
Feng, Zhe, Caballe, Anna, Wainman, Alan, Johnson, Steven, Haensele, Andreas F.M., Cottee, Matthew A., Conduit, Paul T., Lea, Susan M., Raff, Jordan W.
Published in Cell (01.06.2017)
Published in Cell (01.06.2017)
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Journal Article
Structural basis for therapeutic inhibition of complement C5
Jore, Matthijs M, Johnson, Steven, Sheppard, Devon, Barber, Natalie M, Li, Yang I, Nunn, Miles A, Elmlund, Hans, Lea, Susan M
Published in Nature structural & molecular biology (01.05.2016)
Published in Nature structural & molecular biology (01.05.2016)
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Journal Article
Dimerization of complement factor H-related proteins modulates complement activation in vivo
de Jorge, Elena Goicoechea, Caesar, Joseph J. E., Malik, Talat H., Patel, Mitali, Colledge, Matthew, Johnson, Steven, Hakobyan, Svetlana, Morgan, B. Paul, Harris, Claire L., Pickering, Matthew C., Lea, Susan M.
Published in Proceedings of the National Academy of Sciences - PNAS (19.03.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (19.03.2013)
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Journal Article
The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion
Kuhlen, Lucas, Johnson, Steven, Zeitler, Andreas, Bäurle, Sandra, Deme, Justin C., Caesar, Joseph J. E., Debo, Rebecca, Fisher, Joseph, Wagner, Samuel, Lea, Susan M.
Published in Nature communications (10.03.2020)
Published in Nature communications (10.03.2020)
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Journal Article
The Structure of an Injectisome Export Gate Demonstrates Conservation of Architecture in the Core Export Gate between Flagellar and Virulence Type III Secretion Systems
Johnson, Steven, Kuhlen, Lucas, Deme, Justin C, Abrusci, Patrizia, Lea, Susan M
Published in mBio (25.06.2019)
Published in mBio (25.06.2019)
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Journal Article
Structural basis for antibiotic transport and inhibition in PepT2
Parker, Joanne L., Deme, Justin C., Lichtinger, Simon M., Kuteyi, Gabriel, Biggin, Philip C., Lea, Susan M., Newstead, Simon
Published in Nature communications (09.10.2024)
Published in Nature communications (09.10.2024)
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Journal Article
A type VII-secreted lipase toxin with reverse domain arrangement
Garrett, Stephen R., Mietrach, Nicole, Deme, Justin, Bitzer, Alina, Yang, Yaping, Ulhuq, Fatima R., Kretschmer, Dorothee, Heilbronner, Simon, Smith, Terry K., Lea, Susan M., Palmer, Tracy
Published in Nature communications (19.12.2023)
Published in Nature communications (19.12.2023)
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Journal Article
Structures of CD200/CD200 Receptor Family and Implications for Topology, Regulation, and Evolution
Hatherley, Deborah, Lea, Susan M., Johnson, Steven, Barclay, A. Neil
Published in Structure (London) (07.05.2013)
Published in Structure (London) (07.05.2013)
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Journal Article
Architecture of the major component of the type III secretion system export apparatus
Abrusci, Patrizia, Vergara-Irigaray, Marta, Johnson, Steven, Beeby, Morgan D, Hendrixson, David R, Roversi, Pietro, Friede, Miriam E, Deane, Janet E, Jensen, Grant J, Tang, Christoph M, Lea, Susan M
Published in Nature structural & molecular biology (01.01.2013)
Published in Nature structural & molecular biology (01.01.2013)
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Journal Article
Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5b6 and sC5b9
Hadders, Michael A., Bubeck, Doryen, Roversi, Pietro, Hakobyan, Svetlana, Forneris, Federico, Morgan, B. Paul, Pangburn, Michael K., Llorca, Oscar, Lea, Susan M., Gros, Piet
Published in Cell reports (Cambridge) (29.03.2012)
Published in Cell reports (Cambridge) (29.03.2012)
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Journal Article
Fringe-mediated extension of O-linked fucose in the ligand-binding region of Notch1 increases binding to mammalian Notch ligands
Taylor, Paul, Takeuchi, Hideyuki, Sheppard, Devon, Chillakuri, Chandramouli, Lea, Susan M., Haltiwanger, Robert S., Handford, Penny A.
Published in Proceedings of the National Academy of Sciences - PNAS (20.05.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (20.05.2014)
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Journal Article
Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands
Suckling, Richard J, Korona, Boguslawa, Whiteman, Pat, Chillakuri, Chandramouli, Holt, Laurie, Handford, Penny A, Lea, Susan M
Published in The EMBO journal (01.08.2017)
Published in The EMBO journal (01.08.2017)
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