Search Results - "LE POGAM, Carole" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome

BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome

by Gorombei, Petra, Guidez, Fabien, Ganesan, Saravanan, Chiquet, Mathieu, Pellagatti, Andrea, Goursaud, Laure, Tekin, Nilgun, Beurlet, Stephanie, Patel, Satyananda, Guerenne, Laura, Le Pogam, Carole, Setterblad, Niclas, de la Grange, Pierre, LeBoeuf, Christophe, Janin, Anne, Noguera, Maria-Elena, Sarda-Mantel, Laure, Merlet, Pascale, Boultwood, Jacqueline, Konopleva, Marina, Andreeff, Michael, West, Robert, Pla, Marika, Adès, Lionel, Fenaux, Pierre, Krief, Patricia, Chomienne, Christine, Omidvar, Nader, Padua, Rose Ann
Published in International journal of molecular sciences (30.09.2021)

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GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathways

GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathways

by Guerenne, Laura, Beurlet, Stéphanie, Said, Mohamed, Gorombei, Petra, Le Pogam, Carole, Guidez, Fabien, de la Grange, Pierre, Omidvar, Nader, Vanneaux, Valérie, Mills, Ken, Mufti, Ghulam J, Sarda-Mantel, Laure, Noguera, Maria Elena, Pla, Marika, Fenaux, Pierre, Padua, Rose Ann, Chomienne, Christine, Krief, Patricia
Published in Journal of hematology and oncology (27.01.2016)

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BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML by targeting primitive LSK and progenitor cells

BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML by targeting primitive LSK and progenitor cells

by Beurlet, Stephanie, Omidvar, Nader, Gorombei, Petra, Krief, Patricia, Le Pogam, Carole, Setterblad, Niclas, de la Grange, Pierre, Leboeuf, Christophe, Janin, Anne, Noguera, Maria-Elena, Hervatin, Florence, Sarda-Mantel, Laure, Konopleva, Marina, Andreeff, Michael, Tu, Andrea W., Fan, Alice C., Felsher, Dean W., Whetton, Anthony, Pla, Marika, West, Robert, Fenaux, Pierre, Chomienne, Christine, Padua, Rose Ann
Published in Blood (17.10.2013)

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Tracking the Extramedullary PML-RARα-Positive Cell Reservoirs in a Preclinical Model of APL: Biomarker of Long-Term Drug Efficacy

Tracking the Extramedullary PML-RARα-Positive Cell Reservoirs in a Preclinical Model of APL: Biomarker of Long-Term Drug Efficacy

by Pokorna, Katerina, Le Pogam, Carole, Chopin, Martine, Cassinat, Bruno, Fenaux, Pierre, Chomienne, Christine, Padua, Rose Ann, Pla, Marika
Published in Blood (16.11.2012)

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pVAX14 DNA, An Immunoadjuvant, Extends Life-Span As Add-On Treatment To Azacitidine (AZA) In A Mouse Model Of High Risk Myelodysplastic Syndrome (HR-MDS)

pVAX14 DNA, An Immunoadjuvant, Extends Life-Span As Add-On Treatment To Azacitidine (AZA) In A Mouse Model Of High Risk Myelodysplastic Syndrome (HR-MDS)

by Petra, Gorombei, Carole, Le Pogam, Krief, Patricia, Patel, Satyananda, Laura, Guerenne, Robert, West, Marika, Pla, Pierre, Fenaux, Christine, Chomienne, Padua, Rose Ann
Published in Blood (15.11.2013)

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pVAX14 DNA, a Non-Specific DNA Vaccine, Improves Survival In An Acute Promyelocytic Leukemia (APL) Mouse Model Treated With All-Trans Retinoic Acid (ATRA) and Arsenic Trioxide (ATO) and Targets Leukemia Initiating Cells (LICs)

pVAX14 DNA, a Non-Specific DNA Vaccine, Improves Survival In An Acute Promyelocytic Leukemia (APL) Mouse Model Treated With All-Trans Retinoic Acid (ATRA) and Arsenic Trioxide (ATO) and Targets Leukemia Initiating Cells (LICs)

by Patel, Satyananda, Guerenne, Laura, Le Pogam, Carole, Gorombei, Petra, Krief, Patricia, Schlageter, Marie-Helene, West, Robert, Mathews, Vikram, Pla, Marika, Fenaux, Pierre, Chomienne, Christine, Padua, Rose Ann
Published in Blood (15.11.2013)

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Efficacy of ABT-737, a BCL-2 Inhibitor, in an NRAS/BCL2 Mouse Model of High Risk Myelodysplasia (HR-MDS) By Targeting Pathways Identified By Gene Expression Profiling

Efficacy of ABT-737, a BCL-2 Inhibitor, in an NRAS/BCL2 Mouse Model of High Risk Myelodysplasia (HR-MDS) By Targeting Pathways Identified By Gene Expression Profiling

by Padua, Rose Ann, Gorombei, Petra, Beurlet, Stéphanie, Omidvar, Nader, Patel, Satyananda, Guerenne, Laura, Le Pogam, Carole, Setterblad, Niclas, de la Grange, Pierre, Guidez, Fabien, Le Boeuf, Christophe, Janin, Anne, Noguera, Maria-Elena, Sarda-Mantel, Laure, Merlet, Pascal, West, Robert, Pla, Marika, Fenaux, Pierre, Krief, Patricia, Chomienne, Christine
Published in Blood (06.12.2014)

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Tracking the extramedullary PML-RARα-positive cell reservoirs in a preclinical model: Biomarker of long-term drug efficacy

Tracking the extramedullary PML-RARα-positive cell reservoirs in a preclinical model: Biomarker of long-term drug efficacy

by Pokorna, Katerina, Le Pogam, Carole, Chopin, Martine, Balitrand, Nicole, Reboul, Murielle, Cassinat, Bruno, Chomienne, Christine, Padua, Rose Ann, Pla, Marika
Published in Molecular and cellular probes (01.02.2013)

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BCL-2 and Mutant NRAS Interact Physically and Functionally in a Mouse Model of Progressive Myelodysplasia

BCL-2 and Mutant NRAS Interact Physically and Functionally in a Mouse Model of Progressive Myelodysplasia

by OMIDVAR, Nader, KOGAN, Scott, SETTERBLAD, Niclas, FELSHER, Dean, LAGASSE, Eric, MOHAMEDALI, Azim, THOMAS, N. Shaun B, FENAUX, Pierre, FONTENAY, Michaela, PLA, Marika, MUFTI, Ghulam J, WEISSMAN, Irving, BEURLET, Stephanie, CHOMIENNE, Christine, PADUA, Rose Ann, LE POGAM, Carole, JANIN, Anne, WEST, Robert, NOGUERA, Maria-Elena, REBOUL, Murielle, SOULIE, Annie, LEBOEUF, Christophe
Published in Cancer research (Chicago, Ill.) (15.12.2007)

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DNA-mediated adjuvant immunotherapy extends survival in two different mouse models of myeloid malignancies

DNA-mediated adjuvant immunotherapy extends survival in two different mouse models of myeloid malignancies

by Le Pogam, Carole, Patel, Satyananda, Gorombei, Petra, Guerenne, Laura, Krief, Patricia, Omidvar, Nader, Tekin, Nilgun, Bernasconi, Elena, Sicre, Flore, Schlageter, Marie-Helene, Chopin, Martine, Noguera, Maria-Elena, West, Robert, Abu, Ansu, Mathews, Vikram, Pla, Marika, Fenaux, Pierre, Chomienne, Christine, Padua, Rose Ann
Published in Oncotarget (20.10.2015)

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BCL-2 Inhibition with ABT-737 Prolongs Survival in an NRAS/BCL2-Mediated MOUSE MODEL of Myelodyspastic Syndrome (MDS) Progressing to ACUTE Myelogenous Leukemia (AML) by Targeting Leukemia Initiating CELLS

BCL-2 Inhibition with ABT-737 Prolongs Survival in an NRAS/BCL2-Mediated MOUSE MODEL of Myelodyspastic Syndrome (MDS) Progressing to ACUTE Myelogenous Leukemia (AML) by Targeting Leukemia Initiating CELLS

by Gorombei, Petra, Stephanie, Beurlet, Omidvar, Nader, Patricia, Krief, Carole, Le Pogam, de la Grange, Pierre, Christophe, Leboeuf, Janin, Anne, Maria-Elena, Noguera, Konopleva, Marina, Andreeff, Michael, Marika, Pla, Robert, West, Fenaux, Pierre, Chomienne, Christine, Padua, Rose Ann
Published in Blood (16.11.2012)

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DNA vaccination with all-trans retinoic acid treatment induces long-term survival and elicits specific immune responses requiring CD4+ and CD8+ T-cell activation in an acute promyelocytic leukemia mouse model

DNA vaccination with all-trans retinoic acid treatment induces long-term survival and elicits specific immune responses requiring CD4+ and CD8+ T-cell activation in an acute promyelocytic leukemia mouse model

by Furugaki, Kouichi, Pokorna, Katerina, Le Pogam, Carole, Aoki, Masayuki, Reboul, Murielle, Bajzik, Véronique, Krief, Patricia, Janin, Anne, Noguera, Marie-Elena, West, Robert, Charron, Dominique, Chomienne, Christine, Pla, Marika, Moins-Teisserenc, Hélène, Padua, Rose Ann
Published in Blood (21.01.2010)

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DNA and All-Trans Retinoic Acid as Immunotherapy or Add-on Adjuvants to 5-Azacytidine In Myelodysplastic Syndromes

DNA and All-Trans Retinoic Acid as Immunotherapy or Add-on Adjuvants to 5-Azacytidine In Myelodysplastic Syndromes

by Le Pogam, Carole, Krief, Patricia, Beurlet, Stéphanie, Reboul, Murielle, West, Robert, Pla, Marika, Charron, Dominique, Fenaux, Pierre, Chomienne, Christine, Padua, Rose Ann
Published in Blood (19.11.2010)

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Mutant BCL2 Co-Operates with CBFβ/PEBP2β-MYH11 to Promote Expansion of Leukemia Initiating Cells with a Predominantly Pro-Apoptotic Mechanism Via Recruitment of Ras-GTP In a Mouse Model of Progressive Acute Myeloid Leukemia

Mutant BCL2 Co-Operates with CBFβ/PEBP2β-MYH11 to Promote Expansion of Leukemia Initiating Cells with a Predominantly Pro-Apoptotic Mechanism Via Recruitment of Ras-GTP In a Mouse Model of Progressive Acute Myeloid Leukemia

by Omidvar, Nader, Pogam, Carole Le, Beurlet, Stephanie, Noguera, Maria-Elena, Janin, Ann, Kogan, Scott C., Weissman, Irving L., Pla, Marika, Chomienne, Christine, Padua, Rose Ann
Published in Blood (19.11.2010)

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NRAS:BCL-2 Complex Localization Determines Anti-Apoptotic Features Associated with Progressive Disease in Myelodysplastic Syndromes (MDS)

NRAS:BCL-2 Complex Localization Determines Anti-Apoptotic Features Associated with Progressive Disease in Myelodysplastic Syndromes (MDS)

by Padua, Rose Ann, Le Pogam, Carole, Krief, Patricia, Beurlet, Stephanie, Cassinat, Bruno, Cavé, Hélène, Kosmider, Olivier, Setterblad, Niclas, Leboeuf, Christophe, Sarda-Mantel, Laure, Hervatin, Florence, Merlet, Pascal, Noguera, Maria-Elena, Janin, Anne, Pla, Marika, Fontenay, Michaela, Ades, Lionel, Fenaux, Pierre, Chomienne, Christine, Omidvar, Nader
Published in Blood (16.11.2012)

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Localization of the NRAS:BCL-2 complex determines anti-apoptotic features associated with progressive disease in myelodysplastic syndromes

Localization of the NRAS:BCL-2 complex determines anti-apoptotic features associated with progressive disease in myelodysplastic syndromes

by Le Pogam, Carole, Krief, Patricia, Beurlet, Stephanie, Soulié, Annie, Balitrand, Nicole, Cassinat, Bruno, Cavé, Helene, Kosmider, Olivier, Setterblad, Niclas, Leboeuf, Christophe, Sarda-Mantel, Laure, Hervatin, Florence, Merlet, Pascal, Noguera, Maria-Elena, Janin, Anne, Pla, Marika, Fontenay, Michaela, Adès, Lionel, Fenaux, Pierre, Chomienne, Christine, Padua, Rose Ann, Omidvar, Nader
Published in Leukemia research (01.03.2013)

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ABT-737 Targets Leukemic Stem Cells In Mouse Models of Mutant NRASD12/hBCL-2- Mediated Acute Myeloid Leukemia Progression with Increased Survival

ABT-737 Targets Leukemic Stem Cells In Mouse Models of Mutant NRASD12/hBCL-2- Mediated Acute Myeloid Leukemia Progression with Increased Survival

by Padua, Rose Ann, Beurlet, Stephanie, Krief, Patricia, Omidvar, Nader, Pogam, Carole Le, Auboeuf, Didier, de la Grange, Pierre, Soulie, Annie, Janin, Anne, Noguera, Maria-Elena, Merlet, Pascal, Sarda-Mantel, Laure, Fenaux, Pierre, Konopleva, Marina, Andreeff, Michael, Tu, Andrea, Yang, Phoebe, Fan, Alice C., Kogan, Scott C., Weissman, Irving L., Felsher, Dean W., Pla, Marika, West, Robert, Chomienne, Christine
Published in Blood (19.11.2010)

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DNA Vaccination and All-Trans Retinoic Acid Treatment-Induced Long Term Survival Requires CD4+ and CD8+ T-Cell Activation in An APL Mouse Model

DNA Vaccination and All-Trans Retinoic Acid Treatment-Induced Long Term Survival Requires CD4+ and CD8+ T-Cell Activation in An APL Mouse Model

by Padua, Rose Ann, Furugaki, Kouichi, Moins-Teisserenc, Helene, Pokorna, Katerina, Le Pogam, Carole, Reboul, Murielle, Aoki, Masayuki, Bajzik, Veronique, Krief, Patricia, Janin, Anne, Noguera, Maria-Elena, West, Robert, Schlageter, Marie-Helene, Charron, Dominique, Pla, Marika, Chomienne, Christine
Published in Blood (16.11.2008)

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ABT-737 Targets Intrinsic Apoptosis during Cooperation of BCL-2 and Oncogenic NRAS in An in Vivo Progression Model of Myelodysplasia/Acute Myeloid Leukaemia

ABT-737 Targets Intrinsic Apoptosis during Cooperation of BCL-2 and Oncogenic NRAS in An in Vivo Progression Model of Myelodysplasia/Acute Myeloid Leukaemia

by Omidvar, Nader, Beurlet, Stephanie, Le Pogam, Carole, Janin, Anne, Leboeuf, Christophe, Soulie, Annie, Setterblad, Niclas, Noguera, Maria-Elena, Sarda-Mantel, Laure, Merlet, Pascal, Pla, Marika, Kogan, Scott C., Weissman, Irving L, Konopleva, Marina, Bormann, William, Andreeff, Michael, Chomienne, Christine, Padua, Rose Ann
Published in Blood (16.11.2008)

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Retinoic acid receptor α1 variants, RARα1ΔB and RARα1ΔBC, define a new class of nuclear receptor isoforms

Retinoic acid receptor α1 variants, RARα1ΔB and RARα1ΔBC, define a new class of nuclear receptor isoforms

by Parrado, Antonio, Despouy, Gilles, Kraïba, Radhia, Pogam, Carole Le, Dupas, Stéphane, Choquette, Maryline, Robledo, Macarena, Larghero, Jérôme, Bui, Hung, Gall, Isabelle Le, Rochette-Egly, Cécile, Chomienne, Christine, Padua, Rose Ann
Published in Nucleic acids research (24.12.2001)

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