Abstract 1005: Dual targeting of MEK/MAPK1/2 and pro-survival autophagy to optimize antiestrogen treatment toward the eradication of antiestrogen resistant breast cancer
Manning, Mathew, Takhar, Suchreet, Periyasamy-Thandavan, Sudharsan, Cheng, Michael, Barrett, Thomas, Hill, William, Browning, Darren, Thangaraju, Muthusamy, McGee-Lawrence, Meghan, Schoenlein, Patricia V.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
PICOLINIC ACID, A TRYPTOPHAN METABOLITE, DOESN’T AFFECT BONE MINERAL DENSITY BUT UPREGULATES LIPID STORAGE GENES
Isales, Carlos, McGee-Lawrence, Meghan, Hamrick, Mark, Hill, William D, Bollag, Wendy, Ding, Ke-Hong, Shi, Xing-ming, Kennedy, Eileen
Published in Innovation in aging (08.11.2019)
Published in Innovation in aging (08.11.2019)
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Journal Article
AGE-ASSOCIATED INCREASE IN KYNURENINE INHIBITS AUTOPHAGY AND PROMOTES SENESCENCE IN BONE MARROW STEM CELLS
Kondrikov, Dmitry, Elmansi, Ahmed, Shi, Xing-ming, Fulzele, Sadanand, mcGee-Lawrence, Meghan, Hamrick, Mark, Isales, Carlos, Hill, William D
Published in Innovation in aging (08.11.2019)
Published in Innovation in aging (08.11.2019)
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Journal Article
AGE-ASSOCIATED INCREASE IN KYNURENINE SUPPRESSES AUTOPHAGY AND PROMOTES APOPTOSIS IN MESENCHYMAL STEM CELLS
Kondrikov, Dmitry, Elmansi, Ahmed, Bragg, Robert T, Mobley, Tanner, mcGee-Lawrence, Meghan, Hamrick, Mark, Isales, Carlos, Hill, William D
Published in Innovation in aging (08.11.2019)
Published in Innovation in aging (08.11.2019)
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Journal Article
KYNURENINE, AN ENDOGENOUS AHR AGONIST, UPREGULATES CXCL12- AND HDAC3-TARGETING MIRNAS INHIBITING OSTEOGENESIS
Elmansi, Ahmed M, Eisa, Nada, Kondrikov, Dmitry, Fulzele, Sadanand, mcGee-Lawrence, Meghan, Hamrick, Mark, Isales, Carlos, Hill, William D
Published in Innovation in aging (08.11.2019)
Published in Innovation in aging (08.11.2019)
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Journal Article
Abstract 787: FLX925 (AMG 925) is a rationally designed FLT3, CDK4/6 inhibitor that retains potency against clinically relevant secondary resistance mutations in FLT3
Li, Cong, Liang, Lingming, Liu, Liqin, Xia, Zhen, Li, Zhihong, Wang, Xianghong, McGee, Lawrence, Sinclair, Angus, Kamb, Sasha, Wickramasinghe, Dineli, Marubayashi, Sachie, Jaen, Juan C., Fridman, Jordan S., Dai, Kang
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Enhanced prostacyclin formation and Wnt signaling in sclerostin deficient osteocytes and bone
Ryan, Zachary C., Craig, Theodore A., Salisbury, Jeffrey L., Carpio, Lomeli R., McGee-Lawrence, Meghan, Westendorf, Jennifer J., Kumar, Rajiv
Published in Biochemical and biophysical research communications (23.05.2014)
Published in Biochemical and biophysical research communications (23.05.2014)
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Journal Article
AGE-RELATED INCREASE IN KYNURENINE LINKED TO DECREASED OSTEOGENESIS VIA REDUCED SDF-1 IN MESENCHYMAL STEM CELLS
Hussein, K, Elmansi, A, Volkman, B, Shi, X, McGee-Lawrence, M, Hamrick, M, Isales, C, Hill, W
Published in Innovation in aging (11.11.2018)
Published in Innovation in aging (11.11.2018)
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Journal Article
KYNURENIC ACID A TRYPTOPHAN METABOLITE INDUCES BONE LOSS IN MICE
Isales, C, Ding, K, Bollag, W, McGee-Lawrence, M, Hill, W, Shi, X, Elsalanty, M, Hamrick, M
Published in Innovation in aging (11.11.2018)
Published in Innovation in aging (11.11.2018)
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Journal Article
AGE-ASSOCIATED CHANGES IN SDF-1 TARGETING MIRNAS 29B-1-5P AND 141-3P ARE LINKED TO KYNURENINE LEVELS IN MSCS
Elmansi, A, Hussein, K, Fulzele, S, Shi, X, McGee-Lawrence, M, Hamrick, M, Isales, C, Hill, W
Published in Innovation in aging (11.11.2018)
Published in Innovation in aging (11.11.2018)
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Journal Article
Abstract 3663: Discovery of sulfonamide-piperidinones as potent inhibitors of the MDM2-p53 protein-protein interaction
Li, Zhihong, Fu, Jiasheng, Rew, Yosup, Gribble, Michael W., Canon, Jude, Chen, Ada, Eksterowicz, John, Huang, Xin, Jin, Lixia, Lo, Mei-Chu, McGee, Lawrence R., Osgood, Tao, Saiki, Anne Y., Shaffer, Paul, Sun, Daqing, Wortman, Sarah, Ye, Qiuping, Yu, Dongyin, Zhao, Xiaoning, Zhou, Jing, Oliner, Jonathan D., Olson, Steve H., Medina, Julio C.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Animal Models of Bone Disease-B
Secreto, Frank J, McGee-Lawrence, Meghan E, Syed, Farhan A
Published in Animal Models for the Study of Human Disease (2013)
Published in Animal Models for the Study of Human Disease (2013)
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Reference
Synthesis of novel biaryl 2-benzimidazoles and 2-benzothiazoles
Pattabiraman, Kanaka, El-Khouri, Rita, Modi, Kriti, McGee, Lawrence R., Chow, David
Published in Tetrahedron letters (08.04.2009)
Published in Tetrahedron letters (08.04.2009)
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Journal Article
Kynurenine inhibits autophagy and promotes senescence in aged bone marrow mesenchymal stem cells through the aryl hydrocarbon receptor pathway
Kondrikov, Dmitry, Elmansi, Ahmed, Bragg, Robert Tailor, Mobley, Tanner, Barrett, Thomas, Eisa, Nada, Kondrikova, Galina, Schoeinlein, Patricia, Aguilar-Perez, Alexandra, Shi, Xing-Ming, Fulzele, Sadanand, Lawrence, Meghan McGee, Hamrick, Mark, Isales, Carlos, Hill, William
Published in Experimental gerontology (01.02.2020)
Published in Experimental gerontology (01.02.2020)
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Journal Article
Discovery and in Vivo Evaluation of ( S )- N -(1-(7-Fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9 H -purin-6-amine (AMG319) and Related PI3Kδ Inhibitors for Inflammation and Autoimmune Disease
Cushing, Timothy D., Hao, Xiaolin, Shin, Youngsook, Andrews, Kristin, Brown, Matthew, Cardozo, Mario, Chen, Yi, Duquette, Jason, Fisher, Ben, Gonzalez-Lopez de Turiso, Felix, He, Xiao, Henne, Kirk R., Hu, Yi-Ling, Hungate, Randall, Johnson, Michael G., Kelly, Ron C., Lucas, Brian, McCarter, John D., McGee, Lawrence R., Medina, Julio C., San Miguel, Tisha, Mohn, Deanna, Pattaropong, Vatee, Pettus, Liping H., Reichelt, Andreas, Rzasa, Robert M., Seganish, Jennifer, Tasker, Andrew S., Wahl, Robert C., Wannberg, Sharon, Whittington, Douglas A., Whoriskey, John, Yu, Gang, Zalameda, Leeanne, Zhang, Dawei, Metz, Daniela P.
Published in Journal of medicinal chemistry (08.01.2015)
Published in Journal of medicinal chemistry (08.01.2015)
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Journal Article
Abstract A279: Preclinical evaluation of AMG 925, a FLT3/CDK4 dual kinase inhibitor
Dai, Kang, Keegan, Kathleen, Li, Zhihong, Ji, Ma, Li, Cong, Eksterowicz, John, Suzanne, Coberly, Hollenback, David, Weidner, Margret, Huard, Justin, Liang, Lingming, Alba, Grace, Orf, Jessica, Lo, Mei-Chu, Zhao, Sharon, Ngo, Rachel, Chen, Ada, Liu, Lily, Carlson, Timothy, McGee, Lawrence R., Medina, Julio, Kamb, Alexander, Wickramasinghe, Dineli
Published in Molecular cancer therapeutics (01.11.2013)
Published in Molecular cancer therapeutics (01.11.2013)
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Journal Article
Abstract 2351: CDK4/FLT3 dual inhibitors as potential therapeutics for acute myeloid leukemia
Li, Zhihong, Dai, Kang, Keegan, Kathleen, Ma, Ji, Ragains, Mark, Kaizerman, Jacob, McMinn, Dustin, Fu, Jiasheng, Fisher, Benjamin, Gribble, Michael, McGee, Lawrence R., Eksterowicz, John, Li, Cong, Liang, Lingming, Weidner, Margaret, Huard, Justin, Cho, Robert, Carlson, Timothy, Alba, Grace M., Hollenback, David, Hill, John, Beaupre, Darrin, Kamb, Alexander, Wickramasinghe, Dineli, Medina, Julio C.
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Journal Article
Mammalian hibernation as a model of disuse osteoporosis : the effects of physical inactivity on bone metabolism, structure, and strength
MCGEE-LAWRENCE, Meghan E, CAREY, Hannah V, DONAHUE, Seth W
Published in American journal of physiology. Regulatory, integrative and comparative physiology (2008)
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Published in American journal of physiology. Regulatory, integrative and comparative physiology (2008)
Journal Article
Discovery of INT131: A selective PPARI3 modulator that enhances insulin sensitivity
Taygerly, Joshua, McGee, Lawrence, Rubenstein, Steven, Houze, Jonathan, Cushing, Timothy, Li, Yang, Motani, Alykhan, Chen, Jin-Long, Frankmoelle, Walter, Ye, Guosen, Learned, Marc, Jaen, Juan, Miao, Shichang, Timmermans, Pieter, Thoolen, Martin, Kearney, Patrick, Flygare, John, Beckmann, Holger, Weiszmann, Jennifer, Lindstrom, Michelle, Walker, Nigel, Liu, Jinsong, Biermann, Donna, Wang, Zhulun, Hagiwara, Atsushi, Iida, Tetsuya, Aramaki, Hisateru, Kitao, Yuki, Shinkai, Hisashi, Furukawa, Noboru, Nishiu, Jun, Nakamura, Motonao
Published in Bioorganic & medicinal chemistry (01.02.2013)
Published in Bioorganic & medicinal chemistry (01.02.2013)
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