Search Results - "LAWRENCE A. BLACK" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

4-(2-[2-(2(R)-Methylpyrrolidin-1-yl)ethyl]benzofuran-5-yl)benzonitrile and Related 2-Aminoethylbenzofuran H3 Receptor Antagonists Potently Enhance Cognition and Attention

4-(2-[2-(2(R)-Methylpyrrolidin-1-yl)ethyl]benzofuran-5-yl)benzonitrile and Related 2-Aminoethylbenzofuran H3 Receptor Antagonists Potently Enhance Cognition and Attention

by Cowart, Marlon, Faghih, Ramin, Curtis, Michael P, Gfesser, Gregory A, Bennani, Youssef L, Black, Lawrence A, Pan, Liping, Marsh, Kennan C, Sullivan, James P, Esbenshade, Timothy A, Fox, Gerard B, Hancock, Arthur A
Published in Journal of medicinal chemistry (13.01.2005)

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Journal Article

Effects of histamine H3 receptor ligands GT-2331 and ciproxifan in a repeated acquisition avoidance response in the spontaneously hypertensive rat pup

Effects of histamine H3 receptor ligands GT-2331 and ciproxifan in a repeated acquisition avoidance response in the spontaneously hypertensive rat pup

by FOX, Gerard B, JIA BAO PAN, ESBENSHADE, Timothy A, BENNANI, Youssef L, BLACK, Lawrence A, FAGHIH, Ramin, HANCOCK, Arthur A, DECKER, Michael W
Published in Behavioural brain research (01.04.2002)

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Journal Article

In vitro SAR of pyrrolidine-containing histamine H3 receptor antagonists : Trends across multiple chemical series

In vitro SAR of pyrrolidine-containing histamine H3 receptor antagonists : Trends across multiple chemical series

by NERSESIAN, Diana L, BLACK, Lawrence A, MILLER, Thomas R, VORTHERMS, Timothy A, ESBENSHADE, Timothy A, HANCOCK, Arthur A, COWART, Marlon D
Published in Bioorganic & medicinal chemistry letters (2008)

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An Efficient Multigram Synthesis of the Potent Histamine H3 Antagonist GT-2331 and the Reassessment of the Absolute Configuration

An Efficient Multigram Synthesis of the Potent Histamine H3 Antagonist GT-2331 and the Reassessment of the Absolute Configuration

by Liu, Huaqing, Kerdesky, Francis A, Black, Lawrence A, Fitzgerald, Michael, Henry, Rodger, Esbenshade, Timothy A, Hancock, Arthur A, Bennani, Youssef L
Published in Journal of organic chemistry (09.01.2004)

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Differential in vivo effects of H3 receptor ligands in a new mouse dipsogenia model

Differential in vivo effects of H3 receptor ligands in a new mouse dipsogenia model

by FOX, Gerard B, JIA BAO PAN, HANCOCK, Arthur A, DECKER, Michael W, ESBENSHADE, Timothy A, BITNER, R. Scott, NIKKEL, Arthur L, MILLER, Tom, CHAE HEE KANG, BENNANI, Youssef L, BLACK, Lawrence A, FAGHIH, Ramin
Published in Pharmacology, biochemistry and behavior (01.06.2002)

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Structure−Activity Studies on a Series of a 2-Aminopyrimidine-Containing Histamine H4 Receptor Ligands

Structure−Activity Studies on a Series of a 2-Aminopyrimidine-Containing Histamine H4 Receptor Ligands

by Altenbach, Robert J, Adair, Ronald M, Bettencourt, Brian M, Black, Lawrence A, Fix-Stenzel, Shannon R, Gopalakrishnan, Sujatha M, Hsieh, Gin C, Liu, Huaqing, Marsh, Kennan C, McPherson, Michael J, Milicic, Ivan, Miller, Thomas R, Vortherms, Timothy A, Warrior, Usha, Wetter, Jill M, Wishart, Neil, Witte, David G, Honore, Prisca, Esbenshade, Timothy A, Hancock, Arthur A, Brioni, Jorge D, Cowart, Marlon D
Published in Journal of medicinal chemistry (23.10.2008)

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Journal Article

Pharmacological characterization of A-960656, a histamine H3 receptor antagonist with efficacy in animal models of osteoarthritis and neuropathic pain

Pharmacological characterization of A-960656, a histamine H3 receptor antagonist with efficacy in animal models of osteoarthritis and neuropathic pain

by Cowart, Marlon, Hsieh, Gin, Black, Lawrence A., Zhan, CenChen, Gomez, Erica J., Pai, Madhavi, Strakhova, Marina, Manelli, Arlene, Carr, Tracy, Wetter, Jill, Lee, Anthony, Diaz, Gilbert, Garrison, Tiffany, Brioni, Jorge D.
Published in European journal of pharmacology (05.06.2012)

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Diaryldiamines with Dual Inhibition of the Histamine H3 Receptor and the Norepinephrine Transporter and the Efficacy of 4-(3-(Methylamino)-1-phenylpropyl)-6-(2-(pyrrolidin-1-yl)ethoxy)naphthalen-1-ol in Pain

Diaryldiamines with Dual Inhibition of the Histamine H3 Receptor and the Norepinephrine Transporter and the Efficacy of 4-(3-(Methylamino)-1-phenylpropyl)-6-(2-(pyrrolidin-1-yl)ethoxy)naphthalen-1-ol in Pain

by Altenbach, Robert J, Black, Lawrence A, Strakhova, Marina I, Manelli, Arlene M, Carr, Tracy L, Marsh, Kennan C, Wetter, Jill M, Wensink, Erica J, Hsieh, Gin C, Honore, Prisca, Garrison, Tiffany Runyan, Brioni, Jorge D, Cowart, Marlon D
Published in Journal of medicinal chemistry (11.11.2010)

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An Expedient and Multikilogram Synthesis of a Naphthalenoid H3 Antagonist

An Expedient and Multikilogram Synthesis of a Naphthalenoid H3 Antagonist

by Pu, Yu-Ming, Ku, Yi-Yin, Grieme, Timothy, Black, Lawrence A, Bhatia, Ashok V, Cowart, Marlon
Published in Organic process research & development (16.11.2007)

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Journal Article

MODULATORS OF INTEGRATED STRESS PATHWAY

MODULATORS OF INTEGRATED STRESS PATHWAY

by CHUNG SEUNGWON, CARMELA SIDRAUSKI, LAWRENCE A BLACK, TONG YUNSONG, JENNIFER M FROST, MARINA PLIUSCHEV, SHI LEI, CHARLES W HUTCHINS, MICHAEL J DART, XU XIANGDONG, RAMZI FARAH SWEIS, ZHANG QINWEI
Year of Publication 21.02.2024

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Patent

4 -[6 -(2 -Aminoethyl )naphthalen -2 -yl ]benzonitriles are potent histamine H3 receptor antagonists with high CNS penetration

4 -[6 -(2 -Aminoethyl )naphthalen -2 -yl ]benzonitriles are potent histamine H3 receptor antagonists with high CNS penetration

by BLACK, Lawrence A, NERSESIAN, Diana L, SHARMA, Padam, KU, Yi-Yin, BENNANI, Youssef L, MARSH, Kennan C, MILLER, Thomas R, ESBENSHADE, Timothy A, HANCOCK, Arthur A, COWART, Marlon
Published in Bioorganic & medicinal chemistry letters (01.03.2007)

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Journal Article

MODULATORS OF INTEGRATED STRESS PATHWAY

MODULATORS OF INTEGRATED STRESS PATHWAY

by CHUNG SEUNGWON, CARMELA SIDRAUSKI, LAWRENCE A BLACK, TONG YUNSONG, JENNIFER M FROST, MARINA PLIUSCHEV, SHI LEI, CHARLES W HUTCHINS, MICHAEL J DART, XU XIANGDONG, RAMZI FARAH SWEIS, ZHANG QINWEI
Year of Publication 16.09.2021

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Patent

MODULATOR OF INTEGRATED STRESS PATHWAY

MODULATOR OF INTEGRATED STRESS PATHWAY

by CHUNG SEUNGWON, CARMELA SIDRAUSKI, LAWRENCE A BLACK, TONG YUNSONG, JENNIFER M FROST, MARINA PLIUSCHEV, SHI LEI, CHARLES W HUTCHINS, MICHAEL J DART, XU XIANGDONG, RAMZI FARAH SWEIS, ZHANG QINWEI
Year of Publication 29.07.2021

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Patent

Asymmetric Strecker synthesis: isolation of pure enantiomers and mechanistic implications

Asymmetric Strecker synthesis: isolation of pure enantiomers and mechanistic implications

by Stout, David M, Black, Lawrence A, Matier, W. L
Published in Journal of organic chemistry (01.12.1983)

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Journal Article

Structure-Activity Studies on a Series of a 2-Aminopyrimidine-Containing Histamine H-4 Receptor Ligands

Structure-Activity Studies on a Series of a 2-Aminopyrimidine-Containing Histamine H-4 Receptor Ligands

by Altenbach, Robert J., Adair, Ronald M., Bettencourt, Brian M., Black, Lawrence A., Fix-Stenzel, Shannon R., Gopalakrishnan, Suiatha M., Hsieh, Gin C., Liu, Huaqing, Marsh, Kennan C., McPherson, Michael J., Milicic, Ivan, Miller, Thomas R., Vortherms, Timothy A., Warrior, Usha, Wetter, Jill M., Wishart, Neil, Witte, David G., Honore, Prisca, Esbenshade, Timothy A., Hancock, Arthur A., Brioni, Jorge D., Cowart, Marlon D.
Published in Journal of medicinal chemistry (23.10.2008)

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Journal Article

4-(2-[2-(2(R)-methylpyrrolidin-1-yl)ethyl]benzofuran-5-yl)benzonitrile and related 2-aminoethylbenzofuran H-3 receptor antagonists potently enhance cognition and attention

4-(2-[2-(2(R)-methylpyrrolidin-1-yl)ethyl]benzofuran-5-yl)benzonitrile and related 2-aminoethylbenzofuran H-3 receptor antagonists potently enhance cognition and attention

by Cowart, M, Faghih, R, Curtis, MP, Gfesser, GA, Bennani, YL, Black, LA, Pan, LP, Marsh, KC, Sullivan, JP, Esbenshade, TA, Fox, GB, Hancock, AA
Published in Journal of medicinal chemistry (13.01.2005)

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Journal Article

Diaryldiamines with Dual Inhibition of the Histamine H-3 Receptor and the Norepinephrine Transporter and the Efficacy of 4-(3-(Methylamino)-1-phenylpropyl)-6-(2-(pyrrolidin-1-yl)ethoxy)naphthalen-1-ol in Pain

Diaryldiamines with Dual Inhibition of the Histamine H-3 Receptor and the Norepinephrine Transporter and the Efficacy of 4-(3-(Methylamino)-1-phenylpropyl)-6-(2-(pyrrolidin-1-yl)ethoxy)naphthalen-1-ol in Pain

by Altenbach, Robert J., Black, Lawrence A., Strakhova, Marina I., Manelli, Arlene M., Carr, Tracy L., Marsh, Kennan C., Wetter, Jill M., Wensink, Erica J., Hsieh, Gin C., Honore, Prisca, Garrison, Tiffany Runyan, Brioni, Jorge D., Cowart, Marlon D.
Published in Journal of medicinal chemistry (11.11.2010)

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Journal Article

An Expedient and Multikilogram Synthesis of a Naphthalenoid H 3 Antagonist

An Expedient and Multikilogram Synthesis of a Naphthalenoid H 3 Antagonist

by Pu, Yu-Ming, Ku, Yi-Yin, Grieme, Timothy, Black, Lawrence A., Bhatia, Ashok V., Cowart, Marlon
Published in Organic process research & development (01.11.2007)

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Journal Article

Mono- and bis(aminomethyl)phenylacetic acid esters as short-acting antiarrhythmic agents. 2

Mono- and bis(aminomethyl)phenylacetic acid esters as short-acting antiarrhythmic agents. 2

by Chorvat, Robert J, Black, Lawrence A, Ranade, Vasant V, Barcelon-Yang, Cynthia, Stout, David M, Brown, Barry S, Stampfli, Herman F, Quon, Check Y
Published in Journal of medicinal chemistry (01.08.1993)

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Journal Article

In vitro SAR of pyrrolidine-containing histamine H 3 receptor antagonists: Trends across multiple chemical series

In vitro SAR of pyrrolidine-containing histamine H 3 receptor antagonists: Trends across multiple chemical series

by Nersesian, Diana L., Black, Lawrence A., Miller, Thomas R., Vortherms, Timothy A., Esbenshade, Timothy A., Hancock, Arthur A., Cowart, Marlon D.
Published in Bioorganic & medicinal chemistry letters (2008)

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