Nanobody‐mediated complement activation to kill HIV‐infected cells
Pedersen, Maria Lange, Pedersen, Dennis Vestergaard, Winkler, Mikael Becher Lykkegaard, Olesen, Heidi Gytz, Søgaard, Ole Schmeltz, Østergaard, Lars, Laursen, Nick Stub, Rahimic, Anna Halling Folkmar, Tolstrup, Martin
Published in EMBO molecular medicine (11.04.2023)
Published in EMBO molecular medicine (11.04.2023)
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Journal Article
Complement activation by human IgG antibodies to galactose‐α‐1,3‐galactose
Bernth Jensen, Jens Magnus, Laursen, Nick Stub, Jensen, Rasmus Kjeldsen, Andersen, Gregers Rom, Jensenius, Jens Christian, Sørensen, Uffe B. Skov, Thiel, Steffen
Published in Immunology (01.09.2020)
Published in Immunology (01.09.2020)
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Journal Article
Structure-Guided Engineering of a Complement Component C3-Binding Nanobody Improves Specificity and Adds Cofactor Activity
Pedersen, Henrik, Jensen, Rasmus Kjeldsen, Hansen, Annette Gudmann, Petersen, Steen Vang, Thiel, Steffen, Laursen, Nick Stub, Andersen, Gregers Rom
Published in Frontiers in immunology (22.07.2022)
Published in Frontiers in immunology (22.07.2022)
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Journal Article
Isolation and Characterization of Nanobodies against a Zinc-Transporting P-Type ATPase
Longhin, Elena, Grønberg, Christina, Hu, Qiaoxia, Duelli, Annette, Andersen, Kasper, Laursen, Nick, Gourdon, Pontus
Published in Antibodies (Basel) (07.11.2018)
Published in Antibodies (Basel) (07.11.2018)
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Journal Article
보체 조절용 항C3B 항체를 포함하는 융합 단백질
JENSEN RASMUS KJELDSEN, PEDERSEN HENRIK, LAURSEN NICK STUB, ANDERSEN GREGERS ROM
Year of Publication 16.05.2024
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Year of Publication 16.05.2024
Patent
Structural insights into the function-modulating effects of nanobody binding to the integrin receptor αMβ2
Jensen, Rasmus K., Pedersen, Henrik, Lorentzen, Josefine, Laursen, Nick Stub, Vorup-Jensen, Thomas, Andersen, Gregers Rom
Published in The Journal of biological chemistry (01.08.2022)
Published in The Journal of biological chemistry (01.08.2022)
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Journal Article
Introducing site‐specific cysteines into nanobodies for mercury labelling allows de novo phasing of their crystal structures
Hansen, Simon Boje, Laursen, Nick Stub, Andersen, Gregers Rom, Andersen, Kasper R.
Published in Acta crystallographica. Section D, Biological crystallography. (01.10.2017)
Published in Acta crystallographica. Section D, Biological crystallography. (01.10.2017)
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Journal Article
An Ultrahigh-Affinity Complement C4b-Specific Nanobody Inhibits In Vivo Assembly of the Classical Pathway Proconvertase
Zarantonello, Alessandra, Presumey, Jessy, Simoni, Léa, Yalcin, Esra, Fox, Rachel, Hansen, Annette, Olesen, Heidi Gytz, Thiel, Steffen, Johnson, Matthew B, Stevens, Beth, Laursen, Nick Stub, Carroll, Michael C, Andersen, Gregers R
Published in The Journal of immunology (1950) (15.09.2020)
Published in The Journal of immunology (1950) (15.09.2020)
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Journal Article
Structural basis for activation of the complement system by component C4 cleavage
Kidmose, Rune T, Laursen, Nick S, Dobó, József, Kjaer, Troels R, Sirotkina, Sofia, Yatime, Laure, Sottrup-Jensen, Lars, Thiel, Steffen, Gál, Péter, Andersen, Gregers R
Published in Proceedings of the National Academy of Sciences - PNAS (18.09.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (18.09.2012)
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Journal Article
A novel nanobody inhibitor of the alternative pathway
Jensen, Rasmus Kjeldsen, Pihl, Rasmus, Laursen, Nick Stub, Thiel, Steffen, Andersen, Gregers Rom
Published in Molecular immunology (01.09.2017)
Published in Molecular immunology (01.09.2017)
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Journal Article
Two potent C4 and C4b nanobodies inhibiting the classical pathway of the complement system
Zarantonello, Alessandra, Laursen, Nick Stub, Gadeberg, Trine Amalie Fogh, Pedersen, Dennis Vestergaard, Hansen, Annette Gudmann, Schar, Christine, Thiel, Steffen, Andersen, Gregers Rom
Published in Molecular immunology (01.10.2018)
Published in Molecular immunology (01.10.2018)
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Journal Article
FUSION PROTEINS COMPRISING ANTI C3B ANTIBODIES FOR COMPLEMENT REGULATION
JENSEN, Rasmus Kjeldsen, PEDERSEN, Henrik, ANDERSEN, Gregers Rom, LAURSEN, Nick Stub
Year of Publication 10.07.2024
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Year of Publication 10.07.2024
Patent
FUSION PROTEINS COMPRISING ANTI C3B ANTIBODIES FOR COMPLEMENT REGULATION
JENSEN, Rasmus Kjeldsen, PEDERSEN, Henrik, ANDERSEN, Gregers Rom, LAURSEN, Nick Stub
Year of Publication 11.04.2024
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Year of Publication 11.04.2024
Patent
FUSION PROTEINS COMPRISING ANTI C3B ANTIBODIES FOR COMPLEMENT REGULATION
JENSEN, Rasmus Kjeldsen, PEDERSEN, Henrik, ANDERSEN, Gregers Rom, LAURSEN, Nick Stub
Year of Publication 09.03.2023
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Year of Publication 09.03.2023
Patent
FUSION PROTEINS COMPRISING ANTI C3B ANTIBODIES FOR COMPLEMENT REGULATION
JENSEN, RASMUS KJELDSEN, ANDERSEN, GREGERS ROM, LAURSEN, NICK STUB, PEDERSEN, HENRIK
Year of Publication 09.03.2023
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Year of Publication 09.03.2023
Patent
FUSION PROTEINS COMPRISING ANTI C3B SINGLE DOMAIN ANTIBODY FOR COMPLEMENT REGULATION
Rom Andersen, Gregers, Stub Laursen, Nick, Kjeldsen Jensen, Rasmus, Pedersen, Henrik
Year of Publication 01.03.2023
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Year of Publication 01.03.2023
Patent