Glucagon receptor antagonism impairs and glucagon receptor agonism enhances triglycerides metabolism in mice
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Published in Molecular metabolism (Germany) (01.12.2022)
Published in Molecular metabolism (Germany) (01.12.2022)
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Opposing effects of chronic glucagon receptor agonism and antagonism on amino acids, hepatic gene expression, and alpha cells
Elmelund, Emilie, Galsgaard, Katrine D., Johansen, Christian D., Trammell, Samuel A.J., Bomholt, Anna B., Winther-Sørensen, Marie, Hunt, Jenna E., Sørensen, Charlotte M., Kruse, Thomas, Lau, Jesper F., Grevengoed, Trisha J., Holst, Jens J., Wewer Albrechtsen, Nicolai J.
Published in iScience (18.11.2022)
Published in iScience (18.11.2022)
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Discovery and SAR of a Novel Selective and Orally Bioavailable Nonpeptide Classical Competitive Inhibitor Class of Protein-Tyrosine Phosphatase 1B
Andersen, Henrik Sune, Olsen, Ole H, Iversen, Lars F, Sørensen, Anette L. P, Mortensen, Steen B, Christensen, Michael S, Branner, Sven, Hansen, Thomas K, Lau, Jesper F, Jeppesen, Lone, Moran, Edmond J, Su, Jing, Bakir, Farid, Judge, Luke, Shahbaz, Manou, Collins, Tassie, Vo, Todd, Newman, Michael J, Ripka, William C, Møller, Niels Peter H
Published in Journal of medicinal chemistry (26.09.2002)
Published in Journal of medicinal chemistry (26.09.2002)
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Long acting analogue of the calcitonin gene-related peptide induces positive metabolic effects and secretion of the glucagon-like peptide-1
Nilsson, Cecilia, Hansen, Thomas Kruse, Rosenquist, Christian, Hartmann, Bolette, Kodra, János T., Lau, Jesper F., Clausen, Trine Ryberg, Raun, Kirsten, Sams, Anette
Published in European journal of pharmacology (15.02.2016)
Published in European journal of pharmacology (15.02.2016)
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1332-P: Increased and Decreased Glucagon Receptor Signaling Respectively Enhances and Impairs Triglyceride Metabolism Acutely and Chronically
GALSGAARD, KATRINE D., CHRISTENSEN, EMILIE E., BOMHOLT, ANNA B., HUNT, JENNA, KRUSE, THOMAS, LAU, JESPER F., CHRISTOFFERSEN, CHRISTINA, HOLST, JENS J., WEWER ALBRECHTSEN, NICOLAI J.
Published in Diabetes (New York, N.Y.) (01.06.2022)
Published in Diabetes (New York, N.Y.) (01.06.2022)
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214-LB: Activating and Disrupting the Liver–Alpha-Cell Axis Respectively Enhances and Impairs Amino Acid Metabolism and Alpha-Cell Growth
CHRISTENSEN, EMILIE E., GALSGAARD, KATRINE D., JOHANSEN, CHRISTIAN D., TRAMMELL, SAMUEL, BOMHOLT, ANNA B., HUNT, JENNA, KRUSE, THOMAS, LAU, JESPER F., GREVENGOED, TRISHA, HOLST, JENS J., WEWER ALBRECHTSEN, NICOLAI J.
Published in Diabetes (New York, N.Y.) (01.06.2022)
Published in Diabetes (New York, N.Y.) (01.06.2022)
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Identification and in Vivo and in Vitro Characterization of Long Acting and Melanocortin 4 Receptor (MC4-R) Selective α-Melanocyte-Stimulating Hormone (α-MSH) Analogues
Conde-Frieboes, Kilian, Thøgersen, Henning, Lau, Jesper F, Sensfuss, Ulrich, Hansen, Thomas K, Christensen, Leif, Spetzler, Jane, Olsen, Helle B, Nilsson, Cecilia, Raun, Kirsten, Dahl, Kirsten, Hansen, Birgit S, Wulff, Birgitte S
Published in Journal of medicinal chemistry (08.03.2012)
Published in Journal of medicinal chemistry (08.03.2012)
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GIP 유도체 및 이의 용도
FINAN BRIAN, DIMARCHI RICHARD, LIU FA, THØGERSEN HENNING, KNERR PATRICK J, REEDTZ RUNGE STEFFEN, COX NICHOLAS RAYMOND, HOGENDORF WOUTER FREDERIK JOHAN, LAU JESPER F
Year of Publication 14.01.2021
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Year of Publication 14.01.2021
Patent
Parallel solid-phase synthesis of disubstituted (5-biphenyltetrazolyl) hydantoins and thiohydantoins targeting the growth hormone secretagogue receptor
Severinsen, Rune, Lau, Jesper F., Bondensgaard, Kent, Hansen, Birgit S., Begtrup, Mikael, Ankersen, Michael
Published in Bioorganic & medicinal chemistry letters (19.01.2004)
Published in Bioorganic & medicinal chemistry letters (19.01.2004)
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지방산 치환기를 가진 EGF(A) 유사체
LINDEROTH LARS, KODRA JANOS TIBOR, WIECZOREK BIRGIT, THØGERSEN HENNING, CHEN JIANHE, RASMUSSEN SALKA ELBOL, LAU JESPER F, GARIBAY PATRICK WILLIAM
Year of Publication 07.09.2018
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Year of Publication 07.09.2018
Patent
A convenient large-scale chiral synthesis of protected 2-substituted 4-oxo-piperidine derivatives
Lau, Jesper F, Kruse Hansen, Thomas, Paul Kilburn, John, Frydenvang, Karla, Holsworth, Daniel D, Ge, Yu, Uyeda, Roy T, Judge, Luke M, Sune Andersen, Henrik
Published in Tetrahedron (02.09.2002)
Published in Tetrahedron (02.09.2002)
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Journal Article
NOVEL GLUCAGON ANALOGUES
KRUSE THOMAS, NIELSEN PETER KRESTEN, SENSFUSS ULRICH, THOGERSEN HENNING, LAU JESPER F
Year of Publication 10.06.2014
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Year of Publication 10.06.2014
Patent
NOVEL GLUCAGON ANALOGUES
KRUSE THOMAS, KROGH THOMAS NYLANDSTED, SENSFUSS ULRICH, THOGERSEN HENNING, LAU JESPER F
Year of Publication 18.02.2014
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Year of Publication 18.02.2014
Patent