Mechanisms of CFTR functional variants that impair regulated bicarbonate permeation and increase risk for pancreatitis but not for cystic fibrosis
LaRusch, Jessica, Jung, Jinsei, General, Ignacio J, Lewis, Michele D, Park, Hyun Woo, Brand, Randall E, Gelrud, Andres, Anderson, Michelle A, Banks, Peter A, Conwell, Darwin, Lawrence, Christopher, Romagnuolo, Joseph, Baillie, John, Alkaade, Samer, Cote, Gregory, Gardner, Timothy B, Amann, Stephen T, Slivka, Adam, Sandhu, Bimaljit, Aloe, Amy, Kienholz, Michelle L, Yadav, Dhiraj, Barmada, M Michael, Bahar, Ivet, Lee, Min Goo, Whitcomb, David C
Published in PLoS genetics (01.07.2014)
Published in PLoS genetics (01.07.2014)
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Constant-severe pain in chronic pancreatitis is associated with genetic loci for major depression in the NAPS2 cohort
Dunbar, Ellyn, Greer, Phil J., Melhem, Nadine, Alkaade, Samer, Amann, Stephen T., Brand, Randall, Coté, Gregory A., Forsmark, Christopher E., Gardner, Timothy B., Gelrud, Andres, Guda, Nalini M., LaRusch, Jessica, Lewis, Michele D., Machicado, Jorge D., Muniraj, Thiruvengadam, Papachristou, Georgios I., Romagnuolo, Joseph, Sandhu, Bimaljit S., Sherman, Stuart, Wilcox, Charles M., Singh, Vikesh K., Yadav, Dhiraj, Whitcomb, David C.
Published in Journal of gastroenterology (01.10.2020)
Published in Journal of gastroenterology (01.10.2020)
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Journal Article
A sequence upstream of canonical PDZ-binding motif within CFTR COOH-terminus enhances NHERF1 interaction
Sharma, Neeraj, LaRusch, Jessica, Sosnay, Patrick R, Gottschalk, Laura B, Lopez, Andrea P, Pellicore, Matthew J, Evans, Taylor, Davis, Emily, Atalar, Melis, Na, Chan-Hyun, Rosson, Gedge D, Belchis, Deborah, Milewski, Michal, Pandey, Akhilesh, Cutting, Garry R
Published in American journal of physiology. Lung cellular and molecular physiology (01.12.2016)
Published in American journal of physiology. Lung cellular and molecular physiology (01.12.2016)
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Journal Article
AlphaMissense versus laboratory-based pathogenicity prediction of 13 novel missense CPA1 variants from pancreatitis cases
Sándor, Máté, Scheers, Isabelle, Masamune, Atsushi, Witt, Heiko, LaRusch, Jessica, Chen, Jian-Min, Németh, Balázs Csaba, Geisz, Andrea, Uc, Aliye, Sahin-Tóth, Miklós
Published in Gut (10.09.2024)
Published in Gut (10.09.2024)
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Journal Article
Complex Genetics in Pancreatitis: Insights Gained From a New Candidate Locus Panel
Ellison, Mitchell A, Spagnolo, Daniel M, Shelton, Celeste, Orlova, Ekatarina, LaRusch, Jessica, Whitcomb, David C, Haupt, Mark
Published in Pancreas (01.08.2020)
Published in Pancreas (01.08.2020)
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Journal Article
15 – Solute Transporter SLC26A9 Localizes to the Pancreatic Duct Cells and Variants are Associated with Recurrent Acute and Chronic Pancreatitis in Genome-Wide Association Study of 2237 Individuals from the NAPS2 Cohort
Blobner, Brandon M., Shelton, Celeste, LaRusch, Jessica, Greer, Phil J., Papachristou, Georgios I., Yadav, Dhiraj, Whitcomb, David C.
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2019)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2019)
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Differences in Age at Onset of Symptoms, and Effects of Genetic Variants, in Patients With Early vs Late-Onset Idiopathic Chronic Pancreatitis in a North American Cohort
Lewis, Michele D., Talluri, Jyothsna, Wilcox, C. Mel, Abberbock, Judah N., Tang, Gong, Conwell, Darwin L., Banks, Peter A., Cote, Gregory A., Sherman, Stuart, Alkaade, Samer, Gardner, Timothy B., Anderson, Michelle A., Sandhu, Bimaljit S., Muniraj, Thiruvengadam, Forsmark, Chris E., Guda, Nalini, Gelrud, Andres, Romagnuolo, Joseph, Brand, Randall, LaRusch, Jessica, Amann, Stephen T., Slivka, Adam, Whitcomb, David C., Yadav, Dhiraj
Published in Clinical gastroenterology and hepatology (01.02.2021)
Published in Clinical gastroenterology and hepatology (01.02.2021)
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Journal Article
Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1
KRISHNAMACHARY, Balaji, BERG-DIXON, Shannon, SEMENZA, Gregg L, KELLY, Brian, AGANI, Faton, FELDSER, David, FERREIRA, Gloria, IYER, Narayan, LARUSCH, Jessica, PAK, Brian, TAGHAVI, Panthea
Published in Cancer research (Chicago, Ill.) (01.03.2003)
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Published in Cancer research (Chicago, Ill.) (01.03.2003)
Journal Article
Combined Bicarbonate Conductance-Impairing Variants in CFTR and SPINK1 Variants Are Associated With Chronic Pancreatitis in Patients Without Cystic Fibrosis
Schneider, Alexander, Larusch, Jessica, Sun, Xiumei, Aloe, Amy, Lamb, Janette, Hawes, Robert, Cotton, Peter, Brand, Randall E, Anderson, Michelle A, Money, Mary E, Banks, Peter A, Lewis, Michele D, Baillie, John, Sherman, Stuart, DiSario, James, Burton, Frank R, Gardner, Timothy B, Amann, Stephen T, Gelrud, Andres, George, Ryan, Rockacy, Matthew J, Kassabian, Sirvart, Martinson, Jeremy, Slivka, Adam, Yadav, Dhiraj, Oruc, Nevin, Barmada, M. Michael, Frizzell, Raymond, Whitcomb, David C
Published in Gastroenterology (New York, N.Y. 1943) (2011)
Published in Gastroenterology (New York, N.Y. 1943) (2011)
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Journal Article
The Common Chymotrypsinogen C (CTRC) Variant G60G (C.180T) Increases Risk of Chronic Pancreatitis But Not Recurrent Acute Pancreatitis in a North American Population
LaRusch, Jessica, Lozano-Leon, Antonio, Stello, Kimberly, Moore, Amanda, Muddana, Venkata, O'Connell, Michael, Diergaarde, Brenda, Yadav, Dhiraj, Whitcomb, David C
Published in Clinical and translational gastroenterology (01.01.2015)
Published in Clinical and translational gastroenterology (01.01.2015)
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Journal Article
Acute pancreatitis precedes chronic pancreatitis in the majority of patients: Results from the NAPS2 consortium
Singh, Vikesh K., Whitcomb, David C., Banks, Peter A., AlKaade, Samer, Anderson, Michelle A., Amann, Stephen T., Brand, Randall E., Conwell, Darwin L., Cote, Gregory A., Gardner, Timothy B., Gelrud, Andres, Guda, Nalini, Forsmark, Christopher E., Lewis, Michele, Sherman, Stuart, Muniraj, Thiruvengadam, Romagnuolo, Joseph, Tan, Xiaoqing, Tang, Gong, Sandhu, Bimaljit S., Slivka, Adam, Wilcox, C. Mel, Yadav, Dhiraj, Wilcox, C. Mel, Guda, Nalini, Banks, Peter, Conwell, Darwin, Lo, Simon K., Gelrud, Andres, Gardner, Timothy, Baillie, John, Forsmark, Christopher E., Muniraj, Thiruvengadam, Sherman, Stuart, Singh, Vikesh K., Lewis, Michele, Romagnuolo, Joseph, Hawes, Robert, Cote, Gregory A., Lawrence, Christopher, Anderson, Michelle A., Amann, Stephen T., Etemad, Babak, DeMeo, Mark, Kochman, Michael, Abberbock, Judah N., Barmada, M. Michael, Bauer, Emil, Brand, Randall E., Kennard, Elizabeth, LaRusch, Jessica, O'Connell, Michael, Stello, Kimberly, Slivka, Adam, Talluri, Jyothsna, Tang, Gong, Whitcomb, David C., Wisniewski, Stephen R., Yadav, Dhiraj, Burton, Frank, AlKaade, Samer, DiSario, James, Sandhu, Bimaljit S., Money, Mary, Steinberg, William
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.12.2022)
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.12.2022)
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Journal Article
Known genetic susceptibility factors for chronic pancreatitis in patients of European ancestry are rare in patients of African ancestry
Phillips, Anna Evans, LaRusch, Jessica, Greer, Phil, Abberbock, Judah, Alkaade, Samer, Amann, Stephen T., Anderson, Michelle A., Baillie, John, Banks, Peter A., Brand, Randall E., Conwell, Darwin, Coté, Gregory A., Forsmark, Christopher E., Gardner, Timothy B., Gelrud, Andres, Guda, Nalini, Lewis, Michele, Money, Mary E., Muniraj, Thiruvengadam, Sandhu, Bimaljit S., Sherman, Stuart, Singh, Vikesh K., Slivka, Adam, Tang, Gong, Wilcox, C. Mel, Whitcomb, David C., Yadav, Dhiraj
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.07.2018)
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01.07.2018)
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Journal Article
Genetic Risk Score in Diabetes Associated With Chronic Pancreatitis Versus Type 2 Diabetes Mellitus
Goodarzi, Mark O, Nagpal, Tanvi, Greer, Phil, Cui, Jinrui, Chen, Yii-Der I, Guo, Xiuqing, Pankow, James S, Rotter, Jerome I, Alkaade, Samer, Amann, Stephen T, Baillie, John, Banks, Peter A, Brand, Randall E, Conwell, Darwin L, Cote, Gregory A, Forsmark, Christopher E, Gardner, Timothy B, Gelrud, Andres, Guda, Nalini, LaRusch, Jessica, Lewis, Michele D, Money, Mary E, Muniraj, Thiruvengadam, Papachristou, Georgios I, Romagnuolo, Joseph, Sandhu, Bimaljit S, Sherman, Stuart, Singh, Vikesh K, Wilcox, C Mel, Pandol, Stephen J, Park, Walter G, Andersen, Dana K, Bellin, Melena D, Hart, Phil A, Yadav, Dhiraj, Whitcomb, David C
Published in Clinical and translational gastroenterology (20.06.2019)
Published in Clinical and translational gastroenterology (20.06.2019)
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Journal Article
Susceptibility to Alcoholic Pancreatitis but not Sporadic Pancreatitis Is Significantly Reduced by the IL23R R381Q Gene Variant: 239
Barrie, Arthur, Lamb, Janette, Sandhu, Bimaljit, LaRusch, Jessica, Brand, Rhonda, OʼConnell, Michael, Yadav, Dhiraj, Whitcomb, David
Published in The American journal of gastroenterology (01.10.2012)
Published in The American journal of gastroenterology (01.10.2012)
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