Neuronal metabolic rewiring promotes resilience to neurodegeneration caused by mitochondrial dysfunction
Motori, E, Atanassov, I, Kochan, S M V, Folz-Donahue, K, Sakthivelu, V, Giavalisco, P, Toni, N, Puyal, J, Larsson, N-G
Published in Science advances (01.08.2020)
Published in Science advances (01.08.2020)
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MitoPark mice mirror the slow progression of key symptoms and L‐DOPA response in Parkinson's disease
Galter, D., Pernold, K., Yoshitake, T., Lindqvist, E., Hoffer, B., Kehr, J., Larsson, N.‐G., Olson, L.
Published in Genes, brain and behavior (01.03.2010)
Published in Genes, brain and behavior (01.03.2010)
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TWINKLE is an essential mitochondrial helicase required for synthesis of nascent D-loop strands and complete mtDNA replication
Milenkovic, Dusanka, Matic, Stanka, Kühl, Inge, Ruzzenente, Benedetta, Freyer, Christoph, Jemt, Elisabeth, Park, Chan Bae, Falkenberg, Maria, Larsson, Nils-Göran
Published in Human molecular genetics (15.05.2013)
Published in Human molecular genetics (15.05.2013)
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Modulation of mtDNA copy number ameliorates the pathological consequences of a heteroplasmic mtDNA mutation in the mouse
Filograna, R, Koolmeister, C, Upadhyay, M, Pajak, A, Clemente, P, Wibom, R, Simard, M L, Wredenberg, A, Freyer, C, Stewart, J B, Larsson, N G
Published in Science advances (01.04.2019)
Published in Science advances (01.04.2019)
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Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice
LARSSON, N.-G, JIANMING WANG, WILHELMSSON, H, OLDFORS, A, RUSTIN, P, LEWANDOSKI, M, BARSH, G. S, CLAYTON, D. A
Published in Nature genetics (01.03.1998)
Published in Nature genetics (01.03.1998)
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Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression
Wilhelmsson, Hans, Barsh, Gregory S, Wang, Jianming, Rustin, Pierre, Kahn, C. Ronald, Larsson, Nils-Göran, Li, Hong, Brüning, Jens C, Thorén, Peter, Graff, Caroline, Oldfors, Anders, Clayton, David A
Published in Nature genetics (01.01.1999)
Published in Nature genetics (01.01.1999)
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Maintenance and Expression of Mammalian Mitochondrial DNA
Gustafsson, Claes M, Falkenberg, Maria, Larsson, Nils-Göran
Published in Annual review of biochemistry (02.06.2016)
Published in Annual review of biochemistry (02.06.2016)
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Journal Article
Loss of LRPPRC causes ATP synthase deficiency
Mourier, Arnaud, Ruzzenente, Benedetta, Brandt, Tobias, Kühlbrandt, Werner, Larsson, Nils-Göran
Published in Human molecular genetics (15.05.2014)
Published in Human molecular genetics (15.05.2014)
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Late-Onset Corticohippocampal Neurodepletion Attributable to Catastrophic Failure of Oxidative Phosphorylation in MILON Mice
Sorensen, Lene, Ekstrand, Mats, Silva, Jose P, Lindqvist, Eva, Xu, Baoji, Rustin, Pierre, Olson, Lars, Larsson, Nils-Goran
Published in The Journal of neuroscience (15.10.2001)
Published in The Journal of neuroscience (15.10.2001)
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Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo
Murphy, Michael P, Bayir, Hülya, Belousov, Vsevolod, Chang, Christopher J, Davies, Kelvin J A, Davies, Michael J, Dick, Tobias P, Finkel, Toren, Forman, Henry J, Janssen-Heininger, Yvonne, Gems, David, Kagan, Valerian E, Kalyanaraman, Balaraman, Larsson, Nils-Göran, Milne, Ginger L, Nyström, Thomas, Poulsen, Henrik E, Radi, Rafael, Van Remmen, Holly, Schumacker, Paul T, Thornalley, Paul J, Toyokuni, Shinya, Winterbourn, Christine C, Yin, Huiyong, Halliwell, Barry
Published in Nature metabolism (01.06.2022)
Published in Nature metabolism (01.06.2022)
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Small-molecule inhibitors of human mitochondrial DNA transcription
Bonekamp, Nina A, Peter, Bradley, Hillen, Hauke S, Felser, Andrea, Bergbrede, Tim, Choidas, Axel, Horn, Moritz, Unger, Anke, Di Lucrezia, Raffaella, Atanassov, Ilian, Li, Xinping, Koch, Uwe, Menninger, Sascha, Boros, Joanna, Habenberger, Peter, Giavalisco, Patrick, Cramer, Patrick, Denzel, Martin S, Nussbaumer, Peter, Klebl, Bert, Falkenberg, Maria, Gustafsson, Claes M, Larsson, Nils-Göran
Published in Nature (London) (24.12.2020)
Published in Nature (London) (24.12.2020)
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Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid
Kukat, Christian, Davies, Karen M., Wurm, Christian A., Spåhr, Henrik, Bonekamp, Nina A., Kühl, Inge, Joos, Friederike, Polosa, Paola Loguercio, Park, Chan Bae, Posse, Viktor, Falkenberg, Maria, Jakobs, Stefan, Kühlbrandt, Werner, Larsson, Nils-Göran
Published in Proceedings of the National Academy of Sciences - PNAS (08.09.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (08.09.2015)
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