Search Results - "LARBOURET, Christel" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Therapeutic Activity of Anti-AXL Antibody against Triple-Negative Breast Cancer Patient-Derived Xenografts and Metastasis

Therapeutic Activity of Anti-AXL Antibody against Triple-Negative Breast Cancer Patient-Derived Xenografts and Metastasis

by Leconet, Wilhem, Chentouf, Myriam, du Manoir, Stanislas, Chevalier, Clément, Sirvent, Audrey, Aït-Arsa, Imade, Busson, Muriel, Jarlier, Marta, Radosevic-Robin, Nina, Theillet, Charles, Chalbos, Dany, Pasquet, Jean-Max, Pèlegrin, André, Larbouret, Christel, Robert, Bruno
Published in Clinical cancer research (01.06.2017)

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An auristatin‐based antibody‐drug conjugate targeting HER3 enhances the radiation response in pancreatic cancer

An auristatin‐based antibody‐drug conjugate targeting HER3 enhances the radiation response in pancreatic cancer

by Bourillon, Laura, Bourgier, Céline, Gaborit, Nadège, Garambois, Véronique, Llès, Eva, Zampieri, Alexandre, Ogier, Charline, Jarlier, Marta, Radosevic‐Robin, Nina, Orsetti, Béatrice, Delpech, Hélène, Theillet, Charles, Colombo, Pierre‐Emmanuel, Azria, David, Pèlegrin, André, Larbouret, Christel, Chardès, Thierry
Published in International journal of cancer (01.10.2019)

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Biasing human epidermal growth factor receptor 4 (HER4) tyrosine kinase signaling with antibodies: Induction of cell death by antibody‐dependent HER4 intracellular domain trafficking

Biasing human epidermal growth factor receptor 4 (HER4) tyrosine kinase signaling with antibodies: Induction of cell death by antibody‐dependent HER4 intracellular domain trafficking

by Lanotte, Romain, Garambois, Véronique, Gaborit, Nadège, Larbouret, Christel, Musnier, Astrid, Martineau, Pierre, Pèlegrin, André, Chardès, Thierry
Published in Cancer science (01.07.2020)

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Examination of HER3 targeting in cancer using monoclonal antibodies

Examination of HER3 targeting in cancer using monoclonal antibodies

by Gaborit, Nadège, Abdul-Hai, Ali, Mancini, Maicol, Lindzen, Moshit, Lavi, Sara, Leitner, Orith, Mounier, Lucile, Chentouf, Myriam, Dunoyer, Sai, Ghosh, Manjusha, Larbouret, Christel, Chardès, Thierry, Bazin, Hervé, Pèlegrin, André, Sela, Michael, Yarden, Yosef
Published in Proceedings of the National Academy of Sciences - PNAS (20.01.2015)

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Rational development of synergistic combinations of chemotherapy and molecular targeted agents for colorectal cancer treatment

Rational development of synergistic combinations of chemotherapy and molecular targeted agents for colorectal cancer treatment

by Tosi, Diego, Pérez-Gracia, Esther, Atis, Salima, Vié, Nadia, Combès, Eve, Gabanou, Mélissa, Larbouret, Christel, Jarlier, Marta, Mollevi, Caroline, Torro, Adeline, Del Rio, Maguy, Martineau, Pierre, Gongora, Céline
Published in BMC cancer (13.08.2018)

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Design and selection of optimal ErbB-targeting bispecific antibodies in pancreatic cancer

Design and selection of optimal ErbB-targeting bispecific antibodies in pancreatic cancer

by Rabia, Emilia, Garambois, Véronique, Dhommée, Christine, Larbouret, Christel, Lajoie, Laurie, Buscail, Yoan, Jimenez-Dominguez, Gabriel, Choblet-Thery, Sylvie, Liaudet-Coopman, Emmanuelle, Cerutti, Martine, Jarlier, Marta, Ravel, Patrice, Gros, Laurent, Pirot, Nelly, Thibault, Gilles, Zhukovsky, Eugene A, Gérard, Pierre-Emmanuel, Pèlegrin, André, Colinge, Jacques, Chardès, Thierry
Published in Frontiers in immunology (2023)

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Neuregulin 1 Allosterically Enhances the Antitumor Effects of the Noncompeting Anti-HER3 Antibody 9F7-F11 by Increasing Its Binding to HER3

Neuregulin 1 Allosterically Enhances the Antitumor Effects of the Noncompeting Anti-HER3 Antibody 9F7-F11 by Increasing Its Binding to HER3

by Le Clorennec, Christophe, Bazin, Hervé, Dubreuil, Olivier, Larbouret, Christel, Ogier, Charline, Lazrek, Yassamine, Garambois, Véronique, Poul, Marie-Alix, Mondon, Philippe, Barret, Jean-Marc, Mathis, Gérard, Prost, Jean-François, Pèlegrin, André, Chardès, Thierry
Published in Molecular cancer therapeutics (01.07.2017)

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In Pancreatic Carcinoma, Dual EGFR/HER2 Targeting with Cetuximab/Trastuzumab Is More Effective than Treatment with Trastuzumab/Erlotinib or Lapatinib Alone: Implication of Receptors' Down-regulation and Dimers' Disruption

In Pancreatic Carcinoma, Dual EGFR/HER2 Targeting with Cetuximab/Trastuzumab Is More Effective than Treatment with Trastuzumab/Erlotinib or Lapatinib Alone: Implication of Receptors' Down-regulation and Dimers' Disruption

by Larbouret, Christel, Gaborit, Nadège, Chardès, Thierry, Coelho, Mickaël, Campigna, Emmanuelle, Bascoul-Mollevi, Caroline, Mach, Jean-Pierre, Azria, David, Robert, Bruno, Pèlegrin, André
Published in Neoplasia (New York, N.Y.) (01.02.2012)

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ITCH-dependent proteasomal degradation of c-FLIP induced by the anti-HER3 antibody 9F7-F11 promotes DR5/caspase 8-mediated apoptosis of tumor cells

ITCH-dependent proteasomal degradation of c-FLIP induced by the anti-HER3 antibody 9F7-F11 promotes DR5/caspase 8-mediated apoptosis of tumor cells

by Le Clorennec, Christophe, Lazrek, Yassamine, Dubreuil, Olivier, Sampaio, Carla, Larbouret, Christel, Lanotte, Romain, Poul, Marie-Alix, Barret, Jean-Marc, Prost, Jean-François, Pèlegrin, André, Chardès, Thierry
Published in Cell communication and signaling (23.08.2019)

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The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation

The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation

by Le Clorennec, Christophe, Lazrek, Yassamine, Dubreuil, Olivier, Larbouret, Christel, Poul, Marie-Alix, Mondon, Philippe, Melino, Gerry, Pèlegrin, André, Chardès, Thierry
Published in Oncotarget (14.06.2016)

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Anti-tumoral activity of the Pan-HER (Sym013) antibody mixture in gemcitabine-resistant pancreatic cancer models

Anti-tumoral activity of the Pan-HER (Sym013) antibody mixture in gemcitabine-resistant pancreatic cancer models

by Rabia, Emilia, Garambois, Véronique, Hubert, Julie, Bruciamacchie, Marine, Pirot, Nelly, Delpech, Hélène, Broyon, Morgane, Theillet, Charles, Colombo, Pierre-Emmanuel, Vie, Nadia, Tosi, Diego, Gongora, Celine, Khellaf, Lakhdar, Jarlier, Marta, Radosevic-Robin, Nina, Chardès, Thierry, Pèlegrin, André, Larbouret, Christel
Published in mAbs (01.01.2021)

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STING‐ATF3/type I interferon crosstalk: A potential target to improve anti‐tumour immunity in chemotherapy‐treated urothelial carcinoma

STING‐ATF3/type I interferon crosstalk: A potential target to improve anti‐tumour immunity in chemotherapy‐treated urothelial carcinoma

by Fauvre, Alexandra, Machu, Margot, Merienne, Audrey, Vie, Nadia, Bessede, Thomas, Robin, Mathilde, Garambois, Veronique, Taffoni, Clara, Laguette, Nadine, Gervois‐Segain, Nadine, Jarry, Anne, Labarriere, Nathalie, Allory, Yves, Larbouret, Christel, Gros, Laurent, Tosi, Diego, Solit, David B., Pourquier, Philippe, Houédé, Nadine, Gongora, Celine
Published in Clinical and translational medicine (01.09.2024)

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Quantification of HER expression and dimerization in patients' tumor samples using time-resolved Förster resonance energy transfer

Quantification of HER expression and dimerization in patients' tumor samples using time-resolved Förster resonance energy transfer

by Ho-Pun-Cheung, Alexandre, Bazin, Hervé, Gaborit, Nadège, Larbouret, Christel, Garnero, Patrick, Assenat, Eric, Castan, Florence, Bascoul-Mollevi, Caroline, Ramos, Jeanne, Ychou, Marc, Pèlegrin, André, Mathis, Gérard, Lopez-Crapez, Evelyne
Published in PloS one (19.07.2012)

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In vivo Therapeutic Synergism of Anti–Epidermal Growth Factor Receptor and Anti-HER2 Monoclonal Antibodies against Pancreatic Carcinomas

In vivo Therapeutic Synergism of Anti–Epidermal Growth Factor Receptor and Anti-HER2 Monoclonal Antibodies against Pancreatic Carcinomas

by LARBOURET, Christel, ROBERT, Bruno, AZRIA, David, NAVARRO-TEULON, Isabelle, THEZENAS, Simon, LADJEMI, Maha-Zohra, MORISSEAU, Sébastien, CAMPIGNA, Emmanuelle, BIBEAU, Frédéric, MACH, Jean-Pierre, PELEGRIN, André
Published in Clinical cancer research (01.06.2007)

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Anti-HER3 Domain 1 and 3 Antibodies Reduce Tumor Growth by Hindering HER2/HER3 Dimerization and AKT-Induced MDM2, XIAP, and FoxO1 Phosphorylation

Anti-HER3 Domain 1 and 3 Antibodies Reduce Tumor Growth by Hindering HER2/HER3 Dimerization and AKT-Induced MDM2, XIAP, and FoxO1 Phosphorylation

by Lazrek, Yassamine, Dubreuil, Olivier, Garambois, Véronique, Gaborit, Nadège, Larbouret, Christel, Le Clorennec, Christophe, Thomas, Gaelle, Leconet, Wilhem, Jarlier, Marta, Pugnière, Martine, Vié, Nadia, Robert, Bruno, Monnet, Céline, Bouayadi, Khalil, Kharrat, Hakim, Mondon, Philippe, Pèlegrin, André, Chardès, Thierry
Published in Neoplasia (New York, N.Y.) (01.03.2013)

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MHC Class I–Related Chain A Conjugated to Antitumor Antibodies Can Sensitize Tumor Cells to Specific Lysis by Natural Killer Cells

MHC Class I–Related Chain A Conjugated to Antitumor Antibodies Can Sensitize Tumor Cells to Specific Lysis by Natural Killer Cells

by GERMAIN, Claire, LARBOURET, Christel, CESSON, Valérie, DONDA, Alena, HELD, Werner, MACH, Jean-Pierre, PELEGRIN, André, ROBERT, Bruno
Published in Clinical cancer research (15.10.2005)

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Radiocurability by Targeting Tumor Necrosis Factor-α Using a Bispecific Antibody in Carcinoembryonic Antigen Transgenic Mice

Radiocurability by Targeting Tumor Necrosis Factor-α Using a Bispecific Antibody in Carcinoembryonic Antigen Transgenic Mice

by Larbouret, Christel, Ph.D, Robert, Bruno, Ph.D, Linard, Christine, Ph.D, Teulon, Isabelle, Ph.D, Gourgou, Sophie, M.Sc, Bibeau, Frederic, M.D, Martineau, Pierre, Ph.D, Santoro, Lore, M.Sc, Pouget, Jean-Pierre, Ph.D, Pelegrin, Andre, Ph.D, Azria, David, M.D., Ph.D
Published in International journal of radiation oncology, biology, physics (15.11.2007)

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Correction: The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation

Correction: The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation

by Le Clorennec, Christophe, Lazrek, Yassamine, Dubreuil, Olivier, Larbouret, Christel, Poul, Marie-Alix, Mondon, Philippe, Melino, Gerry, Pèlegrin, André, Chardès, Thierry
Published in Oncotarget (11.10.2024)

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Improving Biologics’ Effectiveness in Clinical Oncology: From the Combination of Two Monoclonal Antibodies to Oligoclonal Antibody Mixtures

Improving Biologics’ Effectiveness in Clinical Oncology: From the Combination of Two Monoclonal Antibodies to Oligoclonal Antibody Mixtures

by Larbouret, Christel, Gros, Laurent, Pèlegrin, André, Chardès, Thierry
Published in Cancers (15.09.2021)

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Biasing HER4 tyrosine kinase signaling with antibodies: Induction of cell death by antibody‐dependent HER4 intracellular domain trafficking

Biasing HER4 tyrosine kinase signaling with antibodies: Induction of cell death by antibody‐dependent HER4 intracellular domain trafficking

by Lanotte, Romain, Garambois, Véronique, Gaborit, Nadège, Larbouret, Christel, Musnier, Astrid, Martineau, Pierre, Pèlegrin, André, Chardès, Thierry
Published in Cancer science (2020)

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