Chemical generation of bispecific antibodies
Doppalapudi, Venkata R., Huang, Jie, Liu, Dingguo, Jin, Ping, Liu, Bin, Li, Lingna, Desharnais, Joel, Hagen, Crystal, Levin, Nancy J., Shields, Michael J., Parish, Michelle, Murphy, Robert E., Rosario, Joselyn Del, Oates, Bryan D., Lai, Jing-Yu, Matin, Marla J., Ainekulu, Zemeda, Bhat, Abhijit, Bradshaw, Curt W., Woodnutt, Gary, Lerner, Richard A., Lappe, Rodney W.
Published in Proceedings of the National Academy of Sciences - PNAS (28.12.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (28.12.2010)
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Development of a novel long-acting antidiabetic FGF21 mimetic by targeted conjugation to a scaffold antibody
Huang, Jie, Ishino, Tetsuya, Chen, Gang, Rolzin, Paul, Osothprarop, Trina F, Retting, Kelsey, Li, Lingna, Jin, Ping, Matin, Marla J, Huyghe, Bernard, Talukdar, Saswata, Bradshaw, Curt W, Palanki, Moorthy, Violand, Bernard N, Woodnutt, Gary, Lappe, Rodney W, Ogilvie, Kathleen, Levin, Nancy
Published in The Journal of pharmacology and experimental therapeutics (01.08.2013)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2013)
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Antitumor Efficacy of a Thrombospondin 1 Mimetic CovX-Body
Li, Lingna, Leedom, Tom A, Do, Janet, Huang, Hanhua, Lai, JingYu, Johnson, Kim, Osothprarop, Trina F, Rizzo, John D, Doppalapudi, Venkata R, Bradshaw, Curt W, Lappe, Rodney W, Woodnutt, Gary, Levin, Nancy J, Pirie-Shepherd, Steven R
Published in Translational oncology (01.08.2011)
Published in Translational oncology (01.08.2011)
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Inhibiting complex IL-17A and IL-17RA interactions with a linear peptide
Liu, Shenping, Desharnais, Joel, Sahasrabudhe, Parag V, Jin, Ping, Li, Wei, Oates, Bryan D, Shanker, Suman, Banker, Mary Ellen, Chrunyk, Boris A, Song, Xi, Feng, Xidong, Griffor, Matt, Jimenez, Judith, Chen, Gang, Tumelty, David, Bhat, Abhijit, Bradshaw, Curt W, Woodnutt, Gary, Lappe, Rodney W, Thorarensen, Atli, Qiu, Xiayang, Withka, Jane M, Wood, Lauren D
Published in Scientific reports (17.05.2016)
Published in Scientific reports (17.05.2016)
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Development of novel linkers to conjugate pharmacophores to a carrier antibody
Palanki, Moorthy S.S., Bhat, Abhijit, Lappe, Rodney W., Liu, Bin, Oates, Bryan, Rizzo, John, Stankovic, Nebojsa, Bradshaw, Curt
Published in Bioorganic & medicinal chemistry letters (01.07.2012)
Published in Bioorganic & medicinal chemistry letters (01.07.2012)
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Evolution of Potent and Stable Placental-Growth-Factor-1-Targeting CovX-Bodies from Phage Display Peptide Discovery
Bower, Kristen E, Lam, Son N, Oates, Bryan D, del Rosario, Joselyn R, Corner, Emily, Osothprarop, Trina F, Kinhikar, Arvind G, Hoye, Julie A, Preston, R. Ryan, Murphy, Robert E, Campbell, Lioudmila A, Huang, Hanhua, Jimenez, Judith, Cao, Xia, Chen, Gang, Ainekulu, Zemeda W, Datt, Aakash B, Levin, Nancy J, Doppalapudi, Venkata R, Pirie-Shepherd, Steven R, Bradshaw, Curt, Woodnutt, Gary, Lappe, Rodney W
Published in Journal of medicinal chemistry (10.03.2011)
Published in Journal of medicinal chemistry (10.03.2011)
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Recombinant human complement C5a receptor antagonist reduces infarct size after surgical revascularization
Riley, Robert D., Sato, Hiroki, Zhao, Zhi-Qing, Thourani, Vinod H., Jordan, James E., Fernandez, Adolfo X., Ma, Xin-Liang, Hite, Duncan R., Rigel, Dean F., Pellas, Theodore C., Peppard, Jane, Bill, Kurt A., Lappe, Rodney W., Vinten-Johansen, Jakob
Published in The Journal of thoracic and cardiovascular surgery (01.08.2000)
Published in The Journal of thoracic and cardiovascular surgery (01.08.2000)
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Antihypertensive and Natriuretic Effects of CGS 30440, a Dual Inhibitor of Angiotensin-Converting Enzyme and Neutral Endopeptidase 24.11
Chatelain, R E, Ghai, R D, Trapani, A J, Odorico, L M, Dardik, B N, De Lombaert, S, Lappe, R W, Fink, C A
Published in The Journal of pharmacology and experimental therapeutics (01.03.1998)
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Published in The Journal of pharmacology and experimental therapeutics (01.03.1998)
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Pharmacologic profile of CGS 24128, a potent, long-acting inhibitor of neutral endopeptidase 24.11
Trapani, A J, Beil, M E, Coté, D T, de Lombaert, S, Erion, M D, Gerlock, T E, Ghai, R D, Hopkins, M F, Peppard, J V, Webb, R L
Published in Journal of cardiovascular pharmacology (01.03.1994)
Published in Journal of cardiovascular pharmacology (01.03.1994)
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Hemodynamic effects of calcitonin gene-related peptide in conscious rats
Lappe, Rodney W., Slivjak, Mark J., Todt, Joy A., Wendt, Robert L.
Published in Regulatory peptides (01.12.1987)
Published in Regulatory peptides (01.12.1987)
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Selective Antagonism of Humoral Versus Neural Vasoconstrictor Responses by Nisoldipine
LAPPE, RODNEY W, BARRON, KIRK W, FABER, JAMES E, BRODY, MICHAEL J
Published in Hypertension (Dallas, Tex. 1979) (01.03.1985)
Published in Hypertension (Dallas, Tex. 1979) (01.03.1985)
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Wy-46,300 and Wy-46,531: vascular smooth muscle relaxant/antihypertensive agents with combined Ca2+ antagonist/myosin phosphorylation inhibitory mechanisms
Silver, P J, Sulkowski, T S, Lappe, R W, Wendt, R L
Published in Journal of cardiovascular pharmacology (01.11.1986)
Published in Journal of cardiovascular pharmacology (01.11.1986)
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Functionally Distinct Endothelin B Receptors in Vascular Endothelium and Smooth Muscle
Shetty, S.S., Okada, T., Webb, R.L., Delgrande, D., Lappe, R.W.
Published in Biochemical and biophysical research communications (15.03.1993)
Published in Biochemical and biophysical research communications (15.03.1993)
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Prevention and reversal of cerebral vasospasm by an endothelin-converting enzyme inhibitor, CGS 26303, in an experimental model of subarachnoid hemorrhage
Kwan, A L, Bavbek, M, Jeng, A Y, Maniara, W, Toyoda, T, Lappe, R W, Kassell, N F, Lee, K S
Published in Journal of neurosurgery (01.08.1997)
Published in Journal of neurosurgery (01.08.1997)
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Systemic administration of an inhibitor of endothelin-converting enzyme for attenuation of cerebral vasospasm following experimental subarachnoid hemorrhage
Caner, H H, Kwan, A L, Arthur, A, Jeng, A Y, Lappe, R W, Kassell, N F, Lee, K S
Published in Journal of neurosurgery (01.11.1996)
Published in Journal of neurosurgery (01.11.1996)
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