Aminomethanesulfonic acid illuminates the boundary between full and partial agonists of the pentameric glycine receptor
Ivica, Josip, Zhu, Hongtao, Lape, Remigijus, Gouaux, Eric, Sivilotti, Lucia G
Published in eLife (17.08.2022)
Published in eLife (17.08.2022)
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Mechanisms underlying TARP modulation of the GluA1/2-γ8 AMPA receptor
Herguedas, Beatriz, Kohegyi, Bianka K., Dohrke, Jan-Niklas, Watson, Jake F., Zhang, Danyang, Ho, Hinze, Shaikh, Saher A., Lape, Remigijus, Krieger, James M., Greger, Ingo H.
Published in Nature communications (08.02.2022)
Published in Nature communications (08.02.2022)
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Journal Article
Modulatory mechanisms of TARP γ8-selective AMPA receptor therapeutics
Zhang, Danyang, Lape, Remigijus, Shaikh, Saher A., Kohegyi, Bianka K., Watson, Jake F., Cais, Ondrej, Nakagawa, Terunaga, Greger, Ingo H.
Published in Nature communications (25.03.2023)
Published in Nature communications (25.03.2023)
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Journal Article
Mechanism of gating and partial agonist action in the glycine receptor
Yu, Jie, Zhu, Hongtao, Lape, Remigijus, Greiner, Timo, Du, Juan, Lü, Wei, Sivilotti, Lucia, Gouaux, Eric
Published in Cell (18.02.2021)
Published in Cell (18.02.2021)
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Journal Article
The intracellular domain of homomeric glycine receptors modulates agonist efficacy
Ivica, Josip, Lape, Remigijus, Jazbec, Vid, Yu, Jie, Zhu, Hongtao, Gouaux, Eric, Gold, Matthew G., Sivilotti, Lucia G.
Published in The Journal of biological chemistry (01.01.2021)
Published in The Journal of biological chemistry (01.01.2021)
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Journal Article
Mechanism of activation of the prokaryotic channel ELIC by propylamine: a single-channel study
Marabelli, Alessandro, Lape, Remigijus, Sivilotti, Lucia
Published in The Journal of general physiology (01.01.2015)
Published in The Journal of general physiology (01.01.2015)
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Journal Article
Agonist and Antagonist Binding in Human Glycine Receptors
Yu, Rilei, Hurdiss, Eliott, Greiner, Timo, Lape, Remigijus, Sivilotti, Lucia, Biggin, Philip C
Published in Biochemistry (Easton) (30.09.2014)
Published in Biochemistry (Easton) (30.09.2014)
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Journal Article
Activation Mechanism of Elic by Propylamine
Marabelli, Alessandro, Lape, Remigijus, Sivilotti, Lucia
Published in Biophysical journal (28.01.2014)
Published in Biophysical journal (28.01.2014)
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Journal Article
Alternative Binding Mode of Full and Partial Agonists in a Pentameric Ligand-Gated Ion Channel Stabilises Loop C in an Open Conformation
Dämgen, Marc A., Greiner, Timo, Lape, Remigijus, Sivilotti, Lucia G., Biggin, Philip C.
Published in Biophysical journal (02.02.2018)
Published in Biophysical journal (02.02.2018)
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Journal Article
ELIC Channels Activate Slowly in Response to Agonist Concentration Jumps
Marabelli, Alessandro, Lape, Remigijus, Sivilotti, Lucia
Published in Biophysical journal (31.01.2012)
Published in Biophysical journal (31.01.2012)
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