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Capecitabine and lapatinib for the first‐line treatment of metastatic/recurrent head and neck squamous cell carcinoma
Weiss, Jared M., Bagley, Stephen, Hwang, Wei‐Ting, Bauml, Joshua, Olson, Juneko Grilley, Cohen, Roger B., Hayes, David Neil, Langer, Corey
Published in Cancer (01.08.2016)
Published in Cancer (01.08.2016)
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A sensitive LC-MS-MS assay for the determination of lapatinib in human plasma in subjects with end-stage renal disease receiving hemodialysis
Kocan, Geralyn P., Huang, Mike (Qingtao), Li, Fumin, Pai, Sudhakar
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.10.2018)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.10.2018)
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β1 integrin mediates an alternative survival pathway in breast cancer cells resistant to lapatinib
Huang, Catherine, Park, Catherine C, Hilsenbeck, Susan G, Ward, Robin, Rimawi, Mothaffar F, Wang, Yen-chao, Shou, Jiang, Bissell, Mina J, Osborne, C Kent, Schiff, Rachel
Published in Breast cancer research : BCR (31.08.2011)
Published in Breast cancer research : BCR (31.08.2011)
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A Phase II Study of Lapatinib in Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck
de Souza, Jonas A., Davis, Darren W., Zhang, Yujian, Khattri, Arun, Seiwert, Tanguy Y., Aktolga, Serdal, Wong, Stuart J., Kozloff, Mark F., Nattam, Sreenivasa, Lingen, Mark W., Kunnavakkam, Rangesh, Stenson, Kerstin M., Blair, Elizabeth A., Bozeman, Jeffrey, Dancey, Janet E., Vokes, Everett E., Cohen, Ezra E.W.
Published in Clinical cancer research (15.04.2012)
Published in Clinical cancer research (15.04.2012)
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Lapatinib-Related Rash and Breast Cancer Outcome in the ALTTO Phase III Randomized Trial
Sonnenblick, Amir, de Azambuja, Evandro, Agbor-tarh, Dominique, Bradbury, Ian, Campbell, Christine, Huang, Yingjie, Dueck, Amylou C., Pritchard, Kathleen I., Wolff, Antonio C., Jackisch, Christian, Lang, Istvan, Untch, Michael, Smith, Ian, Boyle, Frances, Xu, Binghe, Gomez, Henry, Perez, Edith A., Piccart, Martine, Azim, Hatem A.
Published in JNCI : Journal of the National Cancer Institute (01.08.2016)
Published in JNCI : Journal of the National Cancer Institute (01.08.2016)
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A Phase II Study with Lead‐In Safety Cohort of 5‐Fluorouracil, Oxaliplatin, and Lapatinib in Combination with Radiation Therapy as Neoadjuvant Treatment for Patients with Localized HER2‐Positive Esophagogastric Adenocarcinomas
Shepard, Gregg, Arrowsmith, Edward R., Murphy, Patrick, Barton, John H., Peyton, James D., Mainwaring, Mark, Blakely, Laura, Maun, Noel A., Bendell, Johanna C.
Published in The oncologist (Dayton, Ohio) (01.10.2017)
Published in The oncologist (Dayton, Ohio) (01.10.2017)
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An open-label study of lapatinib in women with HER-2-negative early breast cancer: the lapatinib pre-surgical study (LPS study)
Coombes, R.C., Tat, T., Miller, M.L., Reise, J.A., Mansi, J.L., Hadjiminas, D.J., Shousha, S., Elsheikh, S.E., Lam, E. W-F., Horimoto, Y., El-Bahrawy, M., Aboagye, E.O., Contractor, K.B., Shaw, J.A., Walker, R.A., Marconell, M.H., Palmieri, C., Stebbing, J.
Published in Annals of oncology (01.04.2013)
Published in Annals of oncology (01.04.2013)
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The effects of lapatinib on cardiac repolarization: results from a placebo controlled, single sequence, crossover study in patients with advanced solid tumors
Coker, Shodeinde A., Hurwitz, Herbert I., Sharma, Sunil, Wang, Ding, Jordaan, Pierre, Zarate, Juan Pablo, Lewis, Lionel D.
Published in Cancer chemotherapy and pharmacology (01.08.2019)
Published in Cancer chemotherapy and pharmacology (01.08.2019)
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Pharmacokinetic evaluation of the vinorelbine–lapatinib combination in the treatment of breast cancer patients
Rezai, Keyvan, Urien, S., Isambert, N., Roche, H., Dieras, V., Berille, J., Bonneterre, J., Brain, E., Lokiec, F.
Published in Cancer chemotherapy and pharmacology (01.12.2011)
Published in Cancer chemotherapy and pharmacology (01.12.2011)
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Multimodality risk adapted therapy with induction carboplatin/paclitaxel/lapatinib for SCCHN amenable to transoral surgery
Weiss, Jared, Hayes, David N., Deal, Allison Mary, Zevallos, Jose, Chera, Bhishamjit S., Paul, Jennifer, Knowles, Mary, Usenko, Dmitriy, Weissler, Mark Christian, Patel, Samip, Grilley-Olson, Juneko E., Hackman, Trevor
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
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Abstract 104: miRNAs in the 14q32 cluster are involved in lapatinib resistance
Chupin, Juliette, Nagano, Ai, Haley, Victoria, Lenihan, Catherine, Cavicchioli, Francesca, O’Leary, Karen, Sahgal, Natasha, Nigro, Cristiana Lo, Shia, Alice, Chelala, Claude, Schmid, Peter
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Abstract PS10-57: A randomized, multicenter, open-label phase II/III study of ARX788 vs Lapatinib and Capecitabine in patients with HER2-positive locally advanced or metastatic breast cancer (ZMC-ARX788-211)
Hu, Xichun, Zhang, Jian, Wang, Leiping, Xia, Gang, Ji, Yanping, Xiong, Gaozhun, Liang, Xuejun, Yao, Sulan, Tian, Feng
Published in Cancer research (Chicago, Ill.) (15.02.2021)
Published in Cancer research (Chicago, Ill.) (15.02.2021)
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Hepatotoxicity associated with lapatinib in an experimental rat model
Demirci, Umut, Buyukberber, Suleyman, Yılmaz, Guldal, Kerem, Mustafa, Coskun, Ugur, Uner, Aytug, Baykara, Meltem, Pasali, Hatice, Benekli, Mustafa
Published in European journal of cancer (1990) (01.01.2012)
Published in European journal of cancer (1990) (01.01.2012)
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A Phase I and Pharmacokinetic Study of Lapatinib in Combination with Letrozole in Patients with Advanced Cancer
Chu, Quincy S.C., Cianfrocca, Mary E., Goldstein, Lori J., Gale, Meg, Murray, Nicholas, Loftiss, Jill, Arya, Nikita, Koch, Kevin M., Pandite, Lini, Fleming, Ronald A., Paul, Elaine, Rowinsky, Eric K.
Published in Clinical cancer research (15.07.2008)
Published in Clinical cancer research (15.07.2008)
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Abstract OT3-01-12: Phase II trial of lapatinib and everolimus for HER2 positive metastatic breast cancer
Barr, JA, Sharma, P, Fabian, CJ, Yeh, H, Baccaray, S, Springer, M, Khan, QJ
Published in Cancer research (Chicago, Ill.) (15.02.2016)
Published in Cancer research (Chicago, Ill.) (15.02.2016)
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Metabolism-Dependent Inhibition of CYP3A4 by Lapatinib: Evidence for Formation of a Metabolic Intermediate Complex with a Nitroso/Oxime Metabolite Formed via a Nitrone Intermediate
Barbara, Joanna E., Kazmi, Faraz, Parkinson, Andrew, Buckley, David B.
Published in Drug metabolism and disposition (01.05.2013)
Published in Drug metabolism and disposition (01.05.2013)
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