Quantitation of Pyridyloxobutyl DNA Adducts of Tobacco-Specific Nitrosamines in Rat Tissue DNA by High-Performance Liquid Chromatography−Electrospray Ionization−Tandem Mass Spectrometry
Lao, Yanbin, Villalta, Peter W, Sturla, Shana J, Wang, Mingyao, Hecht, Stephen S
Published in Chemical research in toxicology (01.05.2006)
Published in Chemical research in toxicology (01.05.2006)
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Genotoxicity of acetaldehyde- and crotonaldehyde-induced 1,N2-propanodeoxyguanosine DNA adducts in human cells
STEIN, Scott, YANBIN LAO, YANG, In-Young, HECHT, Stephen S, MORIYA, Masaaki
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01.09.2006)
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01.09.2006)
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Discovery of ABT-957: 1-Benzyl-5-oxopyrrolidine-2-carboxamides as selective calpain inhibitors with enhanced metabolic stability
Jantos, Katja, Kling, Andreas, Mack, Helmut, Hornberger, Wilfried, Moeller, Achim, Nimmrich, Volker, Lao, Yanbin, Nijsen, Marjoleen
Published in Bioorganic & medicinal chemistry letters (01.08.2019)
Published in Bioorganic & medicinal chemistry letters (01.08.2019)
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Considerations and recommendations for assessment of plasma protein binding and drug-drug interactions for siRNA therapeutics
Humphreys, Sara C, Davis, John A, Iqbal, Sajida, Kamel, Amin, Kulmatycki, Kenneth, Lao, Yanbin, Liu, Xiumin, Rodgers, John, Snoeys, Jan, Vigil, Adam, Weng, Yan, Wiethoff, Christopher M, Wittwer, Matthias B
Published in Nucleic acids research (24.06.2022)
Published in Nucleic acids research (24.06.2022)
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Metabolism and Disposition of a Novel B-Cell Lymphoma-2 Inhibitor Venetoclax in Humans and Characterization of Its Unusual Metabolites
Liu, Hong, Michmerhuizen, Melissa J, Lao, Yanbin, Wan, Katty, Salem, Ahmed Hamed, Sawicki, James, Serby, Michael, Vaidyanathan, Srirajan, Wong, Shekman L, Agarwal, Suresh, Dunbar, Martin, Sydor, Jens, de Morais, Sonia M, Lee, Anthony J
Published in Drug metabolism and disposition (01.03.2017)
Published in Drug metabolism and disposition (01.03.2017)
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Discovery of Novel and Highly Selective Inhibitors of Calpain for the Treatment of Alzheimer’s Disease: 2‑(3-Phenyl‑1H‑pyrazol-1-yl)-nicotinamides
Kling, Andreas, Jantos, Katja, Mack, Helmut, Hornberger, Wilfried, Drescher, Karla, Nimmrich, Volker, Relo, Ana, Wicke, Karsten, Hutchins, Charles W, Lao, Yanbin, Marsh, Kennan, Moeller, Achim
Published in Journal of medicinal chemistry (24.08.2017)
Published in Journal of medicinal chemistry (24.08.2017)
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940-P: 14C-Tirzepatide ADME Studies in Rat and Monkey
MARTIN, JENNIFER, CASSIDY, KENNETH, CZESKIS, BORIS, ALBERTS, JEFF, LAO, YANBIN, GLUFF, JENNIFER, NIEDENTHAL, ANDREA M.
Published in Diabetes (New York, N.Y.) (01.06.2020)
Published in Diabetes (New York, N.Y.) (01.06.2020)
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In Vivo Mechanism of Action of Sodium Caprate for Improving the Intestinal Absorption of a GLP1/GIP Coagonist Peptide
Tran, Huyen, Aihara, Eitaro, Mohammed, Faiz Ahmad, Qu, Hongchang, Riley, Andrew, Su, Yuan, Lai, Xianyin, Huang, Siyuan, Aburub, Aktham, Chen, Jack Jia Hua, Vitale, Olivia Hope, Lao, Yanbin, Estwick, Selina, Qi, Zhonghua, ElSayed, Mohamed E. H.
Published in Molecular pharmaceutics (06.02.2023)
Published in Molecular pharmaceutics (06.02.2023)
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De Novo Design, Synthesis, and Biological Evaluation of 3,4-Disubstituted Pyrrolidine Sulfonamides as Potent and Selective Glycine Transporter 1 Competitive Inhibitors
Wang, Ying, Zhao, Hongyu, Brewer, Jason T, Li, Huanqiu, Lao, Yanbin, Amberg, Willi, Behl, Berthold, Akritopoulou-Zanze, Irini, Dietrich, Justin, Lange, Udo E. W, Pohlki, Frauke, Hoft, Carolin, Hornberger, Wilfried, Djuric, Stevan W, Sydor, Jens, Mezler, Mario, Relo, Ana Lucia, Vasudevan, Anil
Published in Journal of medicinal chemistry (13.09.2018)
Published in Journal of medicinal chemistry (13.09.2018)
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Bispecific Targeting of PD-1 and PD-L1 Enhances T-cell Activation and Antitumor Immunity
Kotanides, Helen, Li, Yiwen, Malabunga, Maria, Carpenito, Carmine, Eastman, Scott W, Shen, Yang, Wang, George, Inigo, Ivan, Surguladze, David, Pennello, Anthony L, Persaud, Krishnadatt, Hindi, Sagit, Topper, Michael, Chen, Xinlei, Zhang, Yiwei, Bulaon, Danielle K, Bailey, Tim, Lao, Yanbin, Han, Bing, Torgerson, Stacy, Chin, Darin, Sonyi, Andreas, Haidar, Jaafar N, Novosiadly, Ruslan D, Moxham, Christopher M, Plowman, Gregory D, Ludwig, Dale L, Kalos, Michael
Published in Cancer immunology research (01.10.2020)
Published in Cancer immunology research (01.10.2020)
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Prediction of Clinical Drug–Drug Interactions of Veliparib (ABT-888) with Human Renal Transporters (OAT1, OAT3, OCT2, MATE1, and MATE2K)
Kikuchi, Ryota, Lao, Yanbin, Bow, Daniel A.J., Chiou, William J., Andracki, Mark E., Carr, Robert A., Voorman, Richard L., De Morais, Sonia M.
Published in Journal of pharmaceutical sciences (01.12.2013)
Published in Journal of pharmaceutical sciences (01.12.2013)
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Discovery of Novel Aminotetralines and Aminochromanes as Selective and Competitive Glycine Transporter 1 (GlyT1) Inhibitors
Amberg, Willi, Lange, Udo E. W, Ochse, Michael, Pohlki, Frauke, Behl, Berthold, Relo, Ana Lucia, Hornberger, Wilfried, Hoft, Carolin, Mezler, Mario, Sydor, Jens, Wang, Ying, Zhao, Hongyu, Brewer, Jason T, Dietrich, Justin, Li, Huanqiu, Akritopoulou-Zanze, Irini, Lao, Yanbin, Hannick, Steven M, Ku, Yi-Yin, Vasudevan, Anil
Published in Journal of medicinal chemistry (13.09.2018)
Published in Journal of medicinal chemistry (13.09.2018)
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Increasing the Reuse of Protein Non-Naïve Nonhuman Primates in Pharmaceutical Drug Discovery and Development: An Overview and Industry Position on the Challenges and Benefits
Mattis, Charles, Bratcher, Natalie, Burns, Monika, Carosino, Christopher, de Zafra, Christina, Fancher, R Marcus, Georgi, Katrin, Graff, Candace, Hukkanen, Renee R, Johnson, Colena, Lao, Yanbin, Lange, Amber, Lee, Donna, Lepherd, Michelle, Maguire, Sean, Malisauskas, Mantas, Manuel, Melinda, Miranda, Sonia, Reed, Lori, Santos, Rosemary, Sayers, Brian, Shaw, David, Shuster, David
Published in International journal of toxicology (01.08.2022)
Published in International journal of toxicology (01.08.2022)
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Journal Article
Genotoxicity of acetaldehyde- and crotonaldehyde-induced 1, N 2-propanodeoxyguanosine DNA adducts in human cells
Stein, Scott, Lao, Yanbin, Yang, In-Young, Hecht, Stephen S., Moriya, Masaaki
Published in Mutation research. Genetic toxicology and environmental mutagenesis (19.09.2006)
Published in Mutation research. Genetic toxicology and environmental mutagenesis (19.09.2006)
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L- CARBIDOPA AND L-DOPA PRODRUGS AND THEIR USE TO TREAT PARKINSON'S DISEASE
HENRY RODGER F, ENRIGHT BRIAN P, KRABBE SCOTT W, MILLER CHRISTOPHER P, HO RAIMUNDO, LAO YANBIN, LOU XIAOCHUN, STAMBULI JAMES, CARDINAL-DAVID BENOIT, STELLA VALENTINO J, HUANG YE, HUTERS ALEXANDER D, MAYER PETER T, KYM PHILIP R, CHAN VINCENT S, MACKEY SEAN E, MATULENKO MARK A, ZHANG GEOFF G, DEMPAH KASSIBLA E, VOIGHT ERIC A, KLIX RUSSELL C, WANG ZHI
Year of Publication 23.07.2024
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Year of Publication 23.07.2024
Patent
Analysis of Pyridyloxobutyl and Pyridylhydroxybutyl DNA Adducts in Extrahepatic Tissues of F344 Rats Treated Chronically with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol
Zhang, Siyi, Wang, Mingyao, Villalta, Peter W, Lindgren, Bruce R, Upadhyaya, Pramod, Lao, Yanbin, Hecht, Stephen S
Published in Chemical research in toxicology (18.05.2009)
Published in Chemical research in toxicology (18.05.2009)
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CARBIDOPA AND L-DOPA PRODRUGS AND METHODS OF USING THE SAME
JAMES STAMBULI, MILLER CHRISTOPHER P, LAO YANBIN, LOU XIAOCHUN, PETER T MAYER, JII WAN, VINCENT S CHAN, SEAN E MACKEY, VALENTINO J STELLA, HUANG YE, ALEXANDER D HUTERS, BRIAN P ENRIGHT, PHILIP R KYM, KASSIBLA E DEMPAH, ERIC A VOIGHT, MATULENKO MARK A, GEOFF G ZHANG, RUSSELL C KLIX, BENOIT CARDINAL-DAVID, RODGER F HENRY, RAIMUNDO HO, SCOTT W KRABBE
Year of Publication 08.12.2023
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Year of Publication 08.12.2023
Patent
L- CARBIDOPA AND L-DOPA PRODRUGS AND THEIR USE TO TREAT PARKINSON'S DISEASE
HENRY RODGER F, ENRIGHT BRIAN P, KRABBE SCOTT W, MILLER CHRISTOPHER P, HO RAIMUNDO, LAO YANBIN, LOU XIAOCHUN, STAMBULI JAMES, STELLA VALENTINO J, HUANG YE, HUTERS ALEXANDER D, MAYER PETER T, KYM PHILIP R, CHAN VINCENT S, CARDINAL DAVID BENOIT, MACKEY SEAN E, MATULENKO MARK A, ZHANG GEOFF G, DEMPAH KASSIBLA E, VOIGHT ERIC A, KLIX RUSSELL C, WANG ZHI
Year of Publication 15.05.2023
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Year of Publication 15.05.2023
Patent
Formation and Accumulation of Pyridyloxobutyl DNA Adducts in F344 Rats Chronically Treated with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of Its Metabolite, 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol
Lao, Yanbin, Yu, Nanxiong, Kassie, Fekadu, Villalta, Peter W, Hecht, Stephen S
Published in Chemical research in toxicology (01.02.2007)
Published in Chemical research in toxicology (01.02.2007)
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