Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation
Lebon, Guillaume, Warne, Tony, Edwards, Patricia C., Bennett, Kirstie, Langmead, Christopher J., Leslie, Andrew G. W., Tate, Christopher G.
Published in Nature (London) (18.05.2011)
Published in Nature (London) (18.05.2011)
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Journal Article
Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists
Zhang, Xin, Belousoff, Matthew J., Zhao, Peishen, Kooistra, Albert J., Truong, Tin T., Ang, Sheng Yu, Underwood, Christina Rye, Egebjerg, Thomas, Šenel, Petr, Stewart, Gregory D., Liang, Yi-Lynn, Glukhova, Alisa, Venugopal, Hari, Christopoulos, Arthur, Furness, Sebastian G.B., Miller, Laurence J., Reedtz-Runge, Steffen, Langmead, Christopher J., Gloriam, David E., Danev, Radostin, Sexton, Patrick M., Wootten, Denise
Published in Molecular cell (05.11.2020)
Published in Molecular cell (05.11.2020)
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Journal Article
Progress in Structure Based Drug Design for G Protein-Coupled Receptors
Congreve, Miles, Langmead, Christopher J, Mason, Jonathan S, Marshall, Fiona H
Published in Journal of medicinal chemistry (14.07.2011)
Published in Journal of medicinal chemistry (14.07.2011)
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Journal Article
Comparative genotypic and phenotypic analysis of human peripheral blood monocytes and surrogate monocyte-like cell lines commonly used in metabolic disease research
Riddy, Darren M, Goy, Emily, Delerive, Philippe, Summers, Roger J, Sexton, Patrick M, Langmead, Christopher J
Published in PloS one (10.05.2018)
Published in PloS one (10.05.2018)
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Journal Article
Structure-based development of a subtype-selective orexin 1 receptor antagonist
Hellmann, Jan, Drabek, Matthäus, Yin, Jie, Gunera, Jakub, Pröll, Theresa, Kraus, Frank, Langmead, Christopher J., Hübner, Harald, Weikert, Dorothee, Kolb, Peter, Rosenbaum, Daniel M., Gmeiner, Peter
Published in Proceedings of the National Academy of Sciences - PNAS (28.07.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (28.07.2020)
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Journal Article
International Union of Basic and Clinical Pharmacology. XC. multisite pharmacology: recommendations for the nomenclature of receptor allosterism and allosteric ligands
Christopoulos, Arthur, Changeux, Jean-Pierre, Catterall, William A, Fabbro, Doriano, Burris, Thomas P, Cidlowski, John A, Olsen, Richard W, Peters, John A, Neubig, Richard R, Pin, Jean-Philippe, Sexton, Patrick M, Kenakin, Terry P, Ehlert, Frederick J, Spedding, Michael, Langmead, Christopher J
Published in Pharmacological reviews (01.10.2014)
Published in Pharmacological reviews (01.10.2014)
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Journal Article
Characterization of a putative orexin receptor in Ciona intestinalis sheds light on the evolution of the orexin/hypocretin system in chordates
Rinne, Maiju K., Urvas, Lauri, Mandrika, Ilona, Fridmanis, Dāvids, Riddy, Darren M., Langmead, Christopher J., Kukkonen, Jyrki P., Xhaard, Henri
Published in Scientific reports (02.04.2024)
Published in Scientific reports (02.04.2024)
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Journal Article
Dynamic allostery governs cyclophilin A–HIV capsid interplay
Lu, Manman, Hou, Guangjin, Zhang, Huilan, Suiter, Christopher L., Ahn, Jinwoo, Byeon, In-Ja L., Perilla, Juan R., Langmead, Christopher J., Hung, Ivan, Gor’kov, Peter L., Gan, Zhehong, Brey, William, Aiken, Christopher, Zhang, Peijun, Schulten, Klaus, Gronenborn, Angela M., Polenova, Tatyana
Published in Proceedings of the National Academy of Sciences - PNAS (24.11.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (24.11.2015)
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Journal Article
Supra‐physiological efficacy at GPCRs: superstition or super agonists?
Langmead, Christopher J, Christopoulos, Arthur
Published in British journal of pharmacology (01.05.2013)
Published in British journal of pharmacology (01.05.2013)
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Journal Article
Allosteric agonists of 7TM receptors: expanding the pharmacological toolbox
Langmead, Christopher J., Christopoulos, Arthur
Published in Trends in pharmacological sciences (Regular ed.) (01.09.2006)
Published in Trends in pharmacological sciences (Regular ed.) (01.09.2006)
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Journal Article
Divergent effects of strontium and calcium‐sensing receptor positive allosteric modulators (calcimimetics) on human osteoclast activity
Diepenhorst, Natalie A, Leach, Katie, Keller, Andrew N, Rueda, Patricia, Cook, Anna E, Pierce, Tracie L, Nowell, Cameron, Pastoureau, Philippe, Sabatini, Massimo, Summers, Roger J, Charman, William N, Sexton, Patrick M, Christopoulos, Arthur, Langmead, Christopher J
Published in British journal of pharmacology (01.11.2018)
Published in British journal of pharmacology (01.11.2018)
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Journal Article
Serum Biomarker Panels for the Detection of Pancreatic Cancer
BRAND, Randall E, NOLEN, Brian M, LANGMEAD, Christopher J, LANDSITTEL, Douglas P, WHITCOMB, David C, GRIZZLE, William E, LOKSHIN, Anna E, ZEH, Herbert J, ALLEN, Peter J, ELOUBEIDI, Mohamad A, GOLDBERG, Michael, ELTON, Eric, ARNOLETTI, Juan P, CHRISTEIN, John D, VICKERS, Selwyn M
Published in Clinical cancer research (15.02.2011)
Published in Clinical cancer research (15.02.2011)
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Journal Article
HIV‑1 Capsid Function Is Regulated by Dynamics: Quantitative Atomic-Resolution Insights by Integrating Magic-Angle-Spinning NMR, QM/MM, and MD
Zhang, Huilan, Hou, Guangjin, Lu, Manman, Ahn, Jinwoo, Byeon, In-Ja L, Langmead, Christopher J, Perilla, Juan R, Hung, Ivan, Gor’kov, Peter L, Gan, Zhehong, Brey, William W, Case, David A, Schulten, Klaus, Gronenborn, Angela M, Polenova, Tatyana
Published in Journal of the American Chemical Society (26.10.2016)
Published in Journal of the American Chemical Society (26.10.2016)
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Journal Article
Murine GPRC6A Mediates Cellular Responses to L-Amino Acids, but Not Osteocalcin Variants
Rueda, Patricia, Harley, Elizabeth, Lu, Yao, Stewart, Gregory D, Fabb, Stewart, Diepenhorst, Natalie, Cremers, Béatrice, Rouillon, Marie-Hélène, Wehrle, Isabelle, Geant, Anne, Lamarche, Gwladys, Leach, Katie, Charman, William N, Christopoulos, Arthur, Summers, Roger J, Sexton, Patrick M, Langmead, Christopher J
Published in PloS one (19.01.2016)
Published in PloS one (19.01.2016)
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Journal Article
Efficient modeling and active learning discovery of biological responses
Naik, Armaghan W, Kangas, Joshua D, Langmead, Christopher J, Murphy, Robert F
Published in PloS one (17.12.2013)
Published in PloS one (17.12.2013)
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Journal Article
“We don’t want to run before we walk”: the attitudes of Australian stakeholders towards using psychedelics for mental health conditions
Kunstler, Breanne, Smith, Liam, Langmead, Christopher, Goodwin, Denise, Wright, Breanna, Hatty, Melissa
Published in Public Health Research & Practice (01.09.2023)
Published in Public Health Research & Practice (01.09.2023)
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