Ketoreductase/Transaminase, One-Pot, Multikilogram Biocatalytic Cascade Reaction
Burns, Michael, Bi, Wenying, Kim, Hui, Lall, Manjinder S, Li, Chao, O’Neill, Brian T
Published in Organic process research & development (16.04.2021)
Published in Organic process research & development (16.04.2021)
Get full text
Journal Article
Application of Flow and Biocatalytic Transaminase Technology for the Synthesis of a 1‑Oxa-8-azaspiro[4.5]decan-3-amine
Kohrt, Jeffrey T, Dorff, Peter H, Burns, Michael, Lee, Chewah, O’Neil, Steven V, Maguire, Robert J, Kumar, Rajesh, Wagenaar, Melissa, Price, Loren, Lall, Manjinder S
Published in Organic process research & development (18.03.2022)
Published in Organic process research & development (18.03.2022)
Get full text
Journal Article
Toward the assembly and characterization of an encoded library hit confirmation platform: Bead-Assisted Ligand Isolation Mass Spectrometry (BALI-MS)
Ratnayake, Anokha S., Flanagan, Mark E., Foley, Timothy L., Hultgren, Scott L., Bellenger, Justin, Montgomery, Justin I., Lall, Manjinder S., Liu, Bo, Ryder, Tim, Kölmel, Dominik K., Shavnya, Andre, Feng, Xidong, Lefker, Bruce, Byrnes, Laura J., Sahasrabudhe, Parag V., Farley, Kathleen A., Chen, Shi, Wan, Jinqiao
Published in Bioorganic & medicinal chemistry (01.07.2021)
Published in Bioorganic & medicinal chemistry (01.07.2021)
Get full text
Journal Article
Pharmacokinetics, mass balance, metabolism, and excretion of the liver-targeted acetyl-CoA carboxylase inhibitor PF-05221304 (clesacostat) in humans
Ryder, Tim F., Bergman, Arthur, King-Ahmad, Amanda, Amin, Neeta B., Lall, Manjinder S., Ballard, T. Eric, Kalgutkar, Amit S.
Published in Xenobiotica (04.03.2022)
Published in Xenobiotica (04.03.2022)
Get full text
Journal Article
Process Development for the Synthesis of Monocyclic β‑Lactam Core 17
Lall, Manjinder S, Tao, Yong, Arcari, Joel T, Boyles, David C, Brown, Matthew F, Damon, David B, Lilley, Susan C, Mitton-Fry, Mark J, Starr, Jeremy, Stewart, Andrew Morgan, Sun, Jianmin
Published in Organic process research & development (16.02.2018)
Published in Organic process research & development (16.02.2018)
Get full text
Journal Article
Enabled Process To Synthesize Monobactam 1 for Early Development
Tao, Yong, Lall, Manjinder S, Boyles, David C, Lilley, Susan C, Pattavina, Sebastian D, Rafka, Robert J, Sitter, Barbara J, Stewart, Andrew Morgan, Szeliga, Jan, Weisenburger, Gerald A
Published in Organic process research & development (15.11.2019)
Published in Organic process research & development (15.11.2019)
Get full text
Journal Article
Pyridone-Conjugated Monobactam Antibiotics with Gram-Negative Activity
Brown, Matthew F, Mitton-Fry, Mark J, Arcari, Joel T, Barham, Rose, Casavant, Jeffrey, Gerstenberger, Brian S, Han, Seungil, Hardink, Joel R, Harris, Thomas M, Hoang, Thuy, Huband, Michael D, Lall, Manjinder S, Lemmon, M. Megan, Li, Chao, Lin, Jian, McCurdy, Sandra P, McElroy, Eric, McPherson, Craig, Marr, Eric S, Mueller, John P, Mullins, Lisa, Nikitenko, Antonia A, Noe, Mark C, Penzien, Joseph, Plummer, Mark S, Schuff, Brandon P, Shanmugasundaram, Veerabahu, Starr, Jeremy T, Sun, Jianmin, Tomaras, Andrew, Young, Jennifer A, Zaniewski, Richard P
Published in Journal of medicinal chemistry (11.07.2013)
Published in Journal of medicinal chemistry (11.07.2013)
Get full text
Journal Article
5-(2-Pyrimidinyl)-imidazo[1,2- a]pyridines are antibacterial agents targeting the ATPase domains of DNA gyrase and topoisomerase IV
Starr, Jeremy T., Sciotti, Richard J., Hanna, Debra L., Huband, Michael D., Mullins, Lisa M., Cai, Hongliang, Gage, Jeffrey W., Lockard, Mandy, Rauckhorst, Mark R., Owen, Robert M., Lall, Manjinder S., Tomilo, Mark, Chen, Huifen, McCurdy, Sandra P., Barbachyn, Michael R.
Published in Bioorganic & medicinal chemistry letters (15.09.2009)
Published in Bioorganic & medicinal chemistry letters (15.09.2009)
Get full text
Journal Article
Utilizing on‐ and off‐line monitoring tools to follow a kinetic resolution step during flow synthesis
Farley, Kathleen A., Reilly, Usa, Anderson, Dennis P., Boscoe, Brian P., Bundesmann, Mark W., Foley, David A., Lall, Manjinder S., Li, Chao, Reese, Matthew R., Yan, Jiangli
Published in Magnetic resonance in chemistry (01.04.2017)
Published in Magnetic resonance in chemistry (01.04.2017)
Get full text
Journal Article
Stereoselective Synthesis of (S)-3-(Methylamino)-3-((R)-pyrrolidin-3-yl)propanenitrile
Lall, Manjinder S, Hoge, Garrett, Tran, Tuan P, Kissel, William, Murphy, Sean T, Taylor, Clarke, Hutchings, Kim, Samas, Brian, Ellsworth, Edmund L, Curran, Timothy, Showalter, H. D. Hollis
Published in Journal of organic chemistry (18.05.2012)
Published in Journal of organic chemistry (18.05.2012)
Get full text
Journal Article
Novel monobactams utilizing a siderophore uptake mechanism for the treatment of gram-negative infections
Mitton-Fry, Mark J., Arcari, Joel T., Brown, Matthew F., Casavant, Jeffrey M., Finegan, Steven M., Flanagan, Mark E., Gao, Hongying, George, David M., Gerstenberger, Brian S., Han, Seungil, Hardink, Joel R., Harris, Thomas M., Hoang, Thuy, Huband, Michael D., Irvine, Rebecca, Lall, Manjinder S., Megan Lemmon, M., Li, Chao, Lin, Jian, McCurdy, Sandra P., Mueller, John P., Mullins, Lisa, Niosi, Mark, Noe, Mark C., Pattavina, David, Penzien, Joseph, Plummer, Mark S., Risley, Hud, Schuff, Brandon P., Shanmugasundaram, Veerabahu, Starr, Jeremy T., Sun, Jianmin, Winton, Jennifer, Young, Jennifer A.
Published in Bioorganic & medicinal chemistry letters (15.09.2012)
Published in Bioorganic & medicinal chemistry letters (15.09.2012)
Get full text
Journal Article
Inhibitors of 3C cysteine proteinases from Picornaviridae
Lall, Manjinder S, Jain, Rajendra P, Vederas, John C
Published in Current topics in medicinal chemistry (01.01.2004)
Published in Current topics in medicinal chemistry (01.01.2004)
Get more information
Journal Article
Dual Modes of Modification of Hepatitis A Virus 3C Protease by a Serine-derived β-Lactone: Selective Crystallization and Formation of a Functional Catalytic Triad in the Active Site
Yin, Jiang, Bergmann, Ernst M., Cherney, Maia M., Lall, Manjinder S., Jain, Rajendra P., Vederas, John C., James, Michael N.G.
Published in Journal of molecular biology (09.12.2005)
Published in Journal of molecular biology (09.12.2005)
Get full text
Journal Article
Synthesis and SAR of novel conformationally-restricted oxazolidinones possessing Gram-positive and fastidious Gram-negative antibacterial activity. Part 1: Substituted pyrazoles
Boyer, Frederick E., Vara Prasad, J.V.N., Choy, Allison L., Chupak, Louis, Dermyer, Michael R., Ding, Qizhu, Huband, Michael D., Jiao, Wenhua, Kaneko, Takushi, Khlebnikov, Vladimir, Kim, Ji-Young, Lall, Manjinder S., Maiti, Samarendra N., Romero, Karina, Wu, Xiujuan
Published in Bioorganic & medicinal chemistry letters (15.08.2007)
Published in Bioorganic & medicinal chemistry letters (15.08.2007)
Get full text
Journal Article
A SN1 mechanistic approach to the Williamson ether reaction via photoredox catalysis applied to benzylic C(sp3)–H bonds
Fitzpatrick, Nicholas A., Zamani, Leila, Das, Mrinmoy, Yayla, Hatice G., Lall, Manjinder S., Musacchio, Patricia Z.
Published in Tetrahedron (22.10.2022)
Published in Tetrahedron (22.10.2022)
Get full text
Journal Article
A photoredox-catalyzed approach for formal hydride abstraction to enable C –H functionalization with nucleophilic partners (F, C, O, N, and Br/Cl)
Zhang, Yufei, Fitzpatrick, Nicholas A., Das, Mrinmoy, Bedre, Ishani P., Yayla, Hatice G., Lall, Manjinder S., Musacchio, Patricia Z.
Published in Chem catalysis (01.06.2022)
Published in Chem catalysis (01.06.2022)
Get full text
Journal Article