Core Refinement toward Permeable β‑Secretase (BACE-1) Inhibitors with Low hERG Activity
Ginman, Tobias, Viklund, Jenny, Malmström, Jonas, Blid, Jan, Emond, Rikard, Forsblom, Rickard, Johansson, Anh, Kers, Annika, Lake, Fredrik, Sehgelmeble, Fernando, Sterky, Karin J, Bergh, Margareta, Lindgren, Anders, Johansson, Patrik, Jeppsson, Fredrik, Fälting, Johanna, Gravenfors, Ylva, Rahm, Fredrik
Published in Journal of medicinal chemistry (13.06.2013)
Published in Journal of medicinal chemistry (13.06.2013)
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Triazolopyrimidinones as γ-secretase modulators: structure-activity relationship, modulator profile, and in vivo profilingDedicated to the memory of our colleague and friend Dr Thierry Groblewski.Electronic supplementary information (ESI) available: Experimental details, 1H-NMR and MS spectra for synthesized compounds. See DOI: 10.1039/c2md20312j
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Year of Publication 30.01.2013
Year of Publication 30.01.2013
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Journal Article
Triazolopyrimidinones as γ-secretase modulators: structure–activity relationship, modulator profile, and in vivo profiling
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Published in MedChemComm (2013)
Published in MedChemComm (2013)
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A General Method for the Preparation of Chiral TREN Derivatives
Pei, Yuxin, Brade, Katja, Brulé, Emilie, Hagberg, Lars, Lake, Fredrik, Moberg, Christina
Published in European Journal of Organic Chemistry (01.07.2005)
Published in European Journal of Organic Chemistry (01.07.2005)
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Book Review
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Chelating phosphines with C2 and C3 symmetry
Brulé, Emilie, Pei, Yuxin, Lake, Fredrik, Rahm, Fredrik, Moberg, Christina
Published in Mendeleev communications (2004)
Published in Mendeleev communications (2004)
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Chiral, Enantiopure Aluminum(III) and Titanium(IV) Azatranes
Forcato, Massimiliano, Lake, Fredrik, Mba Blazquez, Myriam, Renner, Patrick, Crisma, Marco, Gade, Lutz H., Licini, Giulia, Moberg, Christina
Published in European Journal of Inorganic Chemistry (01.03.2006)
Published in European Journal of Inorganic Chemistry (01.03.2006)
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Book Review
Journal Article
Chelating phosphines with C 2 and C 3 symmetry
Brulé, Emilie, Pei, Yuxin, Lake, Fredrik, Rahm, Fredrik, Moberg, Christina
Published in Mendeleev communications (2004)
Published in Mendeleev communications (2004)
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PROCESSO DE PREPARAÇÃO DE ETILENOAMINAS
ROLF KRISTER EDVINSSON, ANTOON JACOB BEREND TEN KATE, EIKE NICOLAS KANTZER, PER FREDRIK OLMO LARSSON, KARL FREDRIK LAKE, INA EHLERS
Year of Publication 11.10.2022
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Year of Publication 11.10.2022
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PROCESSO INTEGRADO PARA FABRICAR COMPOSTOS DE POLIETILENOAMINA SELECIONADOS A PARTIR DO GRUPO DE POLIETILENOAMINAS E HIDROXIETILETILENOAMINAS
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Year of Publication 21.03.2023
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Year of Publication 21.03.2023
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PROCESSO PARA CONVERTER UMA MATÉRIA-PRIMA QUE COMPREENDE ALQUILENOUREIAS CÍCLICAS EM SUAS ALQUILENAMINAS CORRESPONDENTES
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Year of Publication 21.03.2023
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Year of Publication 21.03.2023
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Processo para produzir um produto de ureia de alquileno cíclico
ROLF KRISTER EDVINSSON, ANTOON JACOB BEREND TEN KATE, EHLERS INA, HENDRIK VAN DAM, EIKE NICOLAS KANTZER, JENNY VALBORG THERESE ADRIAN MEREDITH, VENEMAN RENS, KARL FREDRIK LAKE, JOVIC SLAVISA, MICHIEL JOZEF THOMAS RAAIJMAKERS
Year of Publication 12.12.2023
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Year of Publication 12.12.2023
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Processo de preparação de etilenoaminas
ROLF KRISTER EDVINSSON, ANTOON JACOB BEREND TEN KATE, EIKE NICOLAS KANTZER, KARL FREDRIK LAKE, PER FREDRIK OLMO LARSSON
Year of Publication 28.12.2021
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Year of Publication 28.12.2021
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Processo de preparação de etilenoaminas
ROLF KRISTER EDVINSSON, ANTOON JACOB BEREND TEN KATE, EIKE NICOLAS KANTZER, KARL FREDRIK LAKE, PER FREDRIK OLMO LARSSON
Year of Publication 28.12.2021
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Year of Publication 28.12.2021
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Processo para preparar etileno aminas, derivado de ureia de tetraetileno pentamina, derivado de ureia de pentaetileno-hexamina e uso do derivado de ureia
ROLF KRISTER EDVINSSON, ANTOON JACOB BEREND TEN KATE, EHLERS INA, MICHAEL BERTIL EINAR SARNING, HENDRIK VAN DAM, ROBERT KRISTOFFER BERG, EIKE NICOLAS KANTZER, VENEMAN RENS, KARL FREDRIK LAKE, MICHIEL JOZEF THOMAS RAAIJMAKERS
Year of Publication 17.10.2023
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Year of Publication 17.10.2023
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