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Gao, Xuan, Ji, Junyan A., Veeravalli, Karthik, John Wang, Y., Zhang, Taylor, Mcgreevy, William, Zheng, Kai, Kelley, Robert F., Laird, Michael W., Liu, Jun, Cromwell, Mary
Published in Journal of pharmaceutical sciences (01.02.2015)
Published in Journal of pharmaceutical sciences (01.02.2015)
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Enzymatic basis of the Fc-selective intra-chain disulfide reduction and free thiol content variability in an antibody produced in Escherichia coli
Baginski, Tomasz K, Veeravalli, Karthik, McKenna, Rebekah, Williams, Christopher, Wong, Katherine, Tsai, Christina, Hewitt, Daniel, Mani, Karthik, Laird, Michael W
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Published in Microbial cell factories (19.08.2022)
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Development and characterization of an automated imaging workflow to generate clonally‐derived cell lines for therapeutic proteins
Shaw, David, Yim, Mandy, Tsukuda, Joni, Joly, John C., Lin, Andy, Snedecor, Brad, Laird, Michael W., Lang, Steven E.
Published in Biotechnology progress (01.05.2018)
Published in Biotechnology progress (01.05.2018)
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Thioredoxin 1 is responsible for antibody disulfide reduction in CHO cell culture
Koterba, Kristen L., Borgschulte, Trissa, Laird, Michael W.
Published in Journal of biotechnology (01.01.2012)
Published in Journal of biotechnology (01.01.2012)
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Eliminating tyrosine sequence variants in CHO cell lines producing recombinant monoclonal antibodies
Feeney, Lauren, Carvalhal, Veronica, Yu, X. Christopher, Chan, Betty, Michels, David A., Wang, Yajun Jennifer, Shen, Amy, Ressl, Jan, Dusel, Brendon, Laird, Michael W.
Published in Biotechnology and bioengineering (01.04.2013)
Published in Biotechnology and bioengineering (01.04.2013)
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Bacillus anthracis Edema and Lethal Toxin Have Different Hemodynamic Effects but Function Together to Worsen Shock and Outcome in a Rat Model
Cui, Xizhong, Li, Yan, Li, Xuemei, Laird, Michael W., Subramanian, Mani, Moayeri, Mahtab, Leppla, Stephen H., Fitz, Yvonne, Su, Junwu, Sherer, Kevin, Eichacker, Peter Q.
Published in The Journal of infectious diseases (15.02.2007)
Published in The Journal of infectious diseases (15.02.2007)
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Maximizing antibody production in a targeted integration host by optimization of subunit gene dosage and position
Carver, Joe, Ng, Domingos, Zhou, Michelle, Ko, Peggy, Zhan, Dejin, Yim, Mandy, Shaw, David, Snedecor, Brad, Laird, Michael W., Lang, Steven, Shen, Amy, Hu, Zhilan
Published in Biotechnology progress (01.07.2020)
Published in Biotechnology progress (01.07.2020)
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Development of a targeted integration Chinese hamster ovary host directly targeting either one or two vectors simultaneously to a single locus using the Cre/Lox recombinase‐mediated cassette exchange system
Ng, Domingos, Zhou, Meixia, Zhan, Dejin, Yip, Shirley, Ko, Peggy, Yim, Mandy, Modrusan, Zora, Joly, John, Snedecor, Brad, Laird, Michael W., Shen, Amy
Published in Biotechnology progress (01.07.2021)
Published in Biotechnology progress (01.07.2021)
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Use of disposable reactors to generate inoculum cultures for E. coli production fermentations
Mahajan, Ekta, Matthews, Timothy, Hamilton, Ryan, Laird, Michael W.
Published in Biotechnology progress (01.07.2010)
Published in Biotechnology progress (01.07.2010)
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Bax and Bak knockout apoptosis‐resistant Chinese hamster ovary cell lines significantly improve culture viability and titer in intensified fed‐batch culture process
Tang, Danming, Lam, Cynthia, Bauer, Niels, Auslaender, Simon, Snedecor, Brad, Laird, Michael W., Misaghi, Shahram
Published in Biotechnology progress (01.03.2022)
Published in Biotechnology progress (01.03.2022)
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Structural and Functional Characterization of CC Chemokine CCL14
Blain, Katherine Y, Kwiatkowski, Witek, Zhao, Qinghai, La Fleur, David, Naik, Chethana, Chun, Tae-Wook, Tsareva, Tatiana, Kanakaraj, Palanisamy, Laird, Michael W, Shah, Rutul, George, Lisa, Sanyal, Indra, Moore, Paul A, Demeler, Borries, Choe, Senyon
Published in Biochemistry (Easton) (04.09.2007)
Published in Biochemistry (Easton) (04.09.2007)
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Beating the odds: The poisson distribution of all input cells during limiting dilution grossly underestimates whether a cell line is clonally‐derived or not
Zhou, Yizhou, Shaw, David, Lam, Cynthia, Tsukuda, Joni, Yim, Mandy, Tang, Danming, Louie, Salina, Laird, Michael W., Snedecor, Brad, Misaghi, Shahram
Published in Biotechnology progress (01.05.2018)
Published in Biotechnology progress (01.05.2018)
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A strategy to accelerate protein production from a pool of clones in Chinese hamster ovary cells for toxicology studies
Hu, Zhilan, Hsu, Wendy, Pynn, Abby, Ng, Domingos, Quicho, Donna, Adem, Yilma, Kwong, Zephie, Mauger, Brad, Joly, John, Snedecor, Bradley, Laird, Michael W., Andersen, Dana C., Shen, Amy
Published in Biotechnology progress (01.11.2017)
Published in Biotechnology progress (01.11.2017)
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Evaluation of heavy chain C‐terminal deletions on productivity and product quality of monoclonal antibodies in Chinese hamster ovary (CHO) cells
Hu, Zhilan, Tang, Danming, Misaghi, Shahram, Jiang, Guoying, Yu, Christopher, Yim, Mandy, Shaw, David, Snedecor, Brad, Laird, Michael W., Shen, Amy
Published in Biotechnology progress (01.05.2017)
Published in Biotechnology progress (01.05.2017)
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Identification and prevention of antibody disulfide bond reduction during cell culture manufacturing
Trexler-Schmidt, Melody, Sargis, Sandy, Chiu, Jason, Sze-Khoo, Stefanie, Mun, Melissa, Kao, Yung-Hsiang, Laird, Michael W
Published in Biotechnology and bioengineering (15.06.2010)
Published in Biotechnology and bioengineering (15.06.2010)
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Pyruvate Kinase Muscle-1 Expression Appears to Drive Lactogenic Behavior in CHO Cell Lines, Triggering Lower Viability and Productivity: A Case Study
Tang, Danming, Subramanian, Jayashree, Haley, Benjamin, Baker, Jordan, Luo, Lucas, Hsu, Wendy, Liu, Peter, Sandoval, Wendy, Laird, Michael W, Snedecor, Brad, Shiratori, Masaru, Misaghi, Shahram
Published in Biotechnology journal (01.04.2019)
Published in Biotechnology journal (01.04.2019)
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