Myrtleciclib, a CDK4/6/9 Inhibitor for the Treatment of Aggressive Cancers
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Published in Current medicinal chemistry (02.09.2024)
Published in Current medicinal chemistry (02.09.2024)
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Inhibitors of Respiratory Syncytial Virus Replication Target Cotranscriptional mRNA Guanylylation by Viral RNA-Dependent RNA Polymerase
LIUZZI, Michel, MASON, Stephen W, MASSARIOL, Marie-Josée, DO, Florence, WHITEHEAD, Paul, LAMARRE, Lyne, SCOUTEN, Erika, BORDELEAU, Josée, LANDRY, Serge, RANCOURT, Jean, FAZAL, Gulrez, SIMONEAU, Bruno, CARTIER, Mireille, LAWETZ, Carol, MCCOLLUM, Robert S, DANSEREAU, Nathalie, BOLGER, Gordon, LAPEYRE, Nicole, GAUDETTE, Yvon, LAGACE, Lisette
Published in Journal of Virology (01.10.2005)
Published in Journal of Virology (01.10.2005)
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An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus
Lamarre, Daniel, Anderson, Paul C, Bailey, Murray, Beaulieu, Pierre, Bolger, Gordon, Bonneau, Pierre, Bös, Michael, Cameron, Dale R, Cartier, Mireille, Cordingley, Michael G, Faucher, Anne-Marie, Goudreau, Nathalie, Kawai, Stephen H, Kukolj, George, Lagacé, Lisette, LaPlante, Steven R, Narjes, Hans, Poupart, Marc-André, Rancourt, Jean, Sentjens, Roel E, St George, Roger, Simoneau, Bruno, Steinmann, Gerhard, Thibeault, Diane, Tsantrizos, Youla S, Weldon, Steven M, Yong, Chan-Loi, Llinàs-Brunet, Montse
Published in Nature (13.11.2003)
Published in Nature (13.11.2003)
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Molecular Mechanism by Which a Potent Hepatitis C Virus NS3-NS4A Protease Inhibitor Overcomes Emergence of Resistance
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Published in The Journal of biological chemistry (22.02.2013)
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Preclinical Characterization of BI 201335, a C-Terminal Carboxylic Acid Inhibitor of the Hepatitis C Virus NS3-NS4A Protease
WHITE, Peter W, LLINAS-BRUNET, Montse, KUKOLJ, George, AMAD, Ma'an, BETHELL, Richard C, BOLGER, Gordon, CORDINGLEY, Michael G, JIANMIN DUAN, GARNEAU, Michel, LAGACE, Lisette, THIBEAULT, Diane
Published in Antimicrobial Agents and Chemotherapy (01.11.2010)
Published in Antimicrobial Agents and Chemotherapy (01.11.2010)
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In Vitro Resistance Profile of the Hepatitis C Virus NS3 Protease Inhibitor BI 201335
LAGACE, Lisette, WHITE, Peter W, THIBEAULT, Diane, TRIKI, Ibtissem, SONGPING ZHAO, KUKOLJ, George, BOUSQUET, Christiane, DANSEREAU, Nathalie, DO, Florence, LLINAS-BRUNET, Montse, MARQUIS, Martin, MASSARIOL, Marie-Josée, MAURICE, Roger, SPICKLER, Catherine
Published in Antimicrobial Agents and Chemotherapy (01.01.2012)
Published in Antimicrobial Agents and Chemotherapy (01.01.2012)
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Viral Resistance in Hepatitis C Virus Genotype 1-Infected Patients Receiving the NS3 Protease Inhibitor Faldaprevir (BI 201335) in a Phase 1b Multiple-Rising-Dose Study
BERGER, Kristi L, LAGACE, Lisette, TRIKI, Ibtissem, CARTIER, Mireille, MARQUIS, Martin, LAWETZ, Carol, BETHELL, Richard, SCHERER, Joseph, KUKOLJ, George
Published in Antimicrobial Agents and Chemotherapy (01.10.2013)
Published in Antimicrobial Agents and Chemotherapy (01.10.2013)
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Primary infection of mice with high titer inoculum respiratory syncytial virus: characterization and response to antiviral therapy
Bolger, Gordon, Lapeyre, Nicole, Dansereau, Nathalie, Lagacé, Lisette, Berry, Gerald, Klosowski, Katy, Mewhort, Tracy, Liuzzi, Michel
Published in Canadian journal of physiology and pharmacology (01.02.2005)
Published in Canadian journal of physiology and pharmacology (01.02.2005)
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Discovery and Synthesis of C‑Nucleosides as Potential New Anti-HCV Agents
Draffan, Alistair G, Frey, Barbara, Pool, Brett, Gannon, Carlie, Tyndall, Edward M, Lilly, Michael, Francom, Paula, Hufton, Richard, Halim, Rosliana, Jahangiri, Saba, Bond, Silas, Nguyen, Van T. T, Jeynes, Tyrone P, Wirth, Veronika, Luttick, Angela, Tilmanis, Danielle, Thomas, Jesse D, Pryor, Melinda, Porter, Kate, Morton, Craig J, Lin, Bo, Duan, Jianmin, Kukolj, George, Simoneau, Bruno, McKercher, Ginette, Lagacé, Lisette, Amad, Ma’an, Bethell, Richard C, Tucker, Simon P
Published in ACS medicinal chemistry letters (12.06.2014)
Published in ACS medicinal chemistry letters (12.06.2014)
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Improved replicon cellular activity of non-nucleoside allosteric inhibitors of HCV NS5B polymerase: From benzimidazole to indole scaffolds
Beaulieu, Pierre L., Gillard, James, Bykowski, Darren, Brochu, Christian, Dansereau, Nathalie, Duceppe, Jean-Simon, Haché, Bruno, Jakalian, Araz, Lagacé, Lisette, LaPlante, Steven, McKercher, Ginette, Moreau, Elaine, Perreault, Stéphane, Stammers, Timothy, Thauvette, Louise, Warrington, Jeff, Kukolj, George
Published in Bioorganic & medicinal chemistry letters (01.10.2006)
Published in Bioorganic & medicinal chemistry letters (01.10.2006)
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Polyadenylation-dependent screening assay for respiratory syncytial virus RNA transcriptase activity and identification of an inhibitor
Mason, Stephen W., Lawetz, Carol, Gaudette, Yvon, Dô, Florence, Scouten, Erika, Lagacé, Lisette, Simoneau, Bruno, Liuzzi, Michel
Published in Nucleic acids research (01.01.2004)
Published in Nucleic acids research (01.01.2004)
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N-Acetamideindolecarboxylic acid allosteric ‘finger-loop’ inhibitors of the hepatitis C virus NS5B polymerase: discovery and initial optimization studies
Beaulieu, Pierre L., Jolicoeur, Eric, Gillard, James, Brochu, Christian, Coulombe, René, Dansereau, Nathalie, Duan, Jianmin, Garneau, Michel, Jakalian, Araz, Kühn, Peter, Lagacé, Lisette, LaPlante, Steven, McKercher, Ginette, Perrault, Stéphane, Poirier, Martin, Poupart, Marc-André, Stammers, Timothy, Thauvette, Louise, Thavonekham, Bounkham, Kukolj, George
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
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Corrigendum: An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus
Lamarre, Daniel, Anderson, Paul C, Bailey, Murray, Beaulieu, Pierre, Bolger, Gordon, Bonneau, Pierre, Bös, Michael, Cameron, Dale R, Cartier, Mireille, Cordingley, Michael G, Faucher, Anne-Marie, Goudreau, Nathalie, Kawai, Stephen H, Kukolj, George, Lagacé, Lisette, Laplante, Steven R, Narjes, Hans, Poupart, Marc-André, Rancourt, Jean, Sentjens, Roel E, St George, Roger, Simoneau, Bruno, Steinmann, Gerhard, Thibeault, Diane, Tsantrizos, Youla S, Weldon, Steven M, Yong, Chan-Loi, Llinàs-Brunet, Montse
Published in Nature (20.11.2004)
Published in Nature (20.11.2004)
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Calmodulin as a mediator of hormone action and cell regulation
Means, A R, Lagace, L, Guerriero, Jr, V, Chafouleas, J G
Published in Journal of cellular biochemistry (1982)
Published in Journal of cellular biochemistry (1982)
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Down-regulation of estrogen receptors by androgens in the ZR-75-1 human breast cancer cell line
Poulin, R, Simard, J, Labrie, C, Petitclerc, L, Dumont, M, Lagace, L, Labrie, F
Published in Endocrinology (Philadelphia) (01.07.1989)
Published in Endocrinology (Philadelphia) (01.07.1989)
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Evidence of a Conformational Change in the Human Cytomegalovirus Protease upon Binding of Peptidyl-Activated Carbonyl Inhibitors
Bonneau, Pierre R, Grand-Maître, Chantal, Greenwood, Daniel J, Lagacé, Lisette, LaPlante, Steven R, Massariol, Marie-Josée, Ogilvie, William W, O'Meara, Jeff A, Kawai, Stephen H
Published in Biochemistry (Easton) (14.10.1997)
Published in Biochemistry (Easton) (14.10.1997)
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