Roles of G4-DNA and G4-RNA in Class Switch Recombination and Additional Regulations in B-Lymphocytes
Dézé, Ophélie, Laffleur, Brice, Cogné, Michel
Published in Molecules (Basel, Switzerland) (24.01.2023)
Published in Molecules (Basel, Switzerland) (24.01.2023)
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Noncoding RNA processing by DIS3 regulates chromosomal architecture and somatic hypermutation in B cells
Laffleur, Brice, Lim, Junghyun, Zhang, Wanwei, Chen, Yiyun, Pefanis, Evangelos, Bizarro, Jonathan, Batista, Carolina R., Wu, Lijing, Economides, Aris N., Wang, Jiguang, Basu, Uttiya
Published in Nature genetics (01.02.2021)
Published in Nature genetics (01.02.2021)
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Nuclear Proximity of Mtr4 to RNA Exosome Restricts DNA Mutational Asymmetry
Lim, Junghyun, Giri, Pankaj Kumar, Kazadi, David, Laffleur, Brice, Zhang, Wanwei, Grinstein, Veronika, Pefanis, Evangelos, Brown, Lewis M., Ladewig, Erik, Martin, Ophélie, Chen, Yuling, Rabadan, Raul, Boyer, François, Rothschild, Gerson, Cogné, Michel, Pinaud, Eric, Deng, Haiteng, Basu, Uttiya
Published in Cell (20.04.2017)
Published in Cell (20.04.2017)
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B Cell Intrinsic Mechanisms Constraining IgE Memory
Laffleur, Brice, Debeaupuis, Orianne, Dalloul, Zeinab, Cogné, Michel
Published in Frontiers in immunology (13.11.2017)
Published in Frontiers in immunology (13.11.2017)
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The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity
Rialdi, Alexander, Hultquist, Judd, Jimenez-Morales, David, Peralta, Zuleyma, Campisi, Laura, Fenouil, Romain, Moshkina, Natasha, Wang, Zhen Zhen, Laffleur, Brice, Kaake, Robyn M., McGregor, Michael J., Haas, Kelsey, Pefanis, Evangelos, Albrecht, Randy A., Pache, Lars, Chanda, Sumit, Jen, Joanna, Ochando, Jordi, Byun, Minji, Basu, Uttiya, García-Sastre, Adolfo, Krogan, Nevan, van Bakel, Harm, Marazzi, Ivan
Published in Cell (04.05.2017)
Published in Cell (04.05.2017)
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G-quadruplex DNA targeting alters class-switch recombination in B cells and attenuates allergic inflammation
Dalloul, Zeinab, Chenuet, Pauline, Dalloul, Iman, Boyer, François, Aldigier, Jean-Claude, Laffleur, Brice, El Makhour, Yolla, Ryffel, Bernhard, Quesniaux, Valerie F.J., Togbé, Dieudonnée, Mergny, Jean-Louis, Cook-Moreau, Jeanne, Cogné, Michel
Published in Journal of allergy and clinical immunology (01.10.2018)
Published in Journal of allergy and clinical immunology (01.10.2018)
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Self-Restrained B Cells Arise following Membrane IgE Expression
Laffleur, Brice, Duchez, Sophie, Tarte, Karin, Denis-Lagache, Nicolas, Péron, Sophie, Carrion, Claire, Denizot, Yves, Cogné, Michel
Published in Cell reports (Cambridge) (17.02.2015)
Published in Cell reports (Cambridge) (17.02.2015)
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Mechanism of noncoding RNA-associated N6-methyladenosine recognition by an RNA processing complex during IgH DNA recombination
Nair, Lekha, Zhang, Wanwei, Laffleur, Brice, Jha, Mukesh K., Lim, Junghyun, Lee, Heather, Wu, Lijing, Alvarez, Nehemiah S., Liu, Zhi-ping, Munteanu, Emilia L., Swayne, Theresa, Hanna, Jacob H., Ding, Lei, Rothschild, Gerson, Basu, Uttiya
Published in Molecular cell (07.10.2021)
Published in Molecular cell (07.10.2021)
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AID-Driven Deletion Causes Immunoglobulin Heavy Chain Locus Suicide Recombination in B Cells
Péron, Sophie, Laffleur, Brice, Denis-Lagache, Nicolas, Cook-Moreau, Jeanne, Tinguely, Aurélien, Delpy, Laurent, Denizot, Yves, Pinaud, Eric, Cogné, Michel
Published in Science (American Association for the Advancement of Science) (18.05.2012)
Published in Science (American Association for the Advancement of Science) (18.05.2012)
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UnAIDed Class Switching in Activated B-Cells Reveals Intrinsic Features of a Self-Cleaving IgH Locus
Dalloul, Iman, Laffleur, Brice, Dalloul, Zeinab, Wehbi, Batoul, Jouan, Florence, Brauge, Baptiste, Derouault, Paco, Moreau, Jeanne, Kracker, Sven, Fischer, Alain, Durandy, Anne, Le Noir, Sandrine, Cogné, Michel
Published in Frontiers in immunology (28.10.2021)
Published in Frontiers in immunology (28.10.2021)
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Journal Article
Attempts to evaluate locus suicide recombination and its potential role in B cell negative selection in the mouse
Denis-Lagache, Nicolas, Oblet, Christelle, Marchiol, Tiffany, Baylet, Audrey, Têteau, Ophélie, Dalloul, Iman, Dalloul, Zeinab, Zawil, Lina, Dézé, Ophélie, Cook-Moreau, Jeanne, Saintamand, Alexis, Boutouil, Hend, Khamlichi, Ahmed Amine, Carrion, Claire, Péron, Sophie, Le Noir, Sandrine, Laffleur, Brice, Cogné, Michel
Published in Frontiers in immunology (2023)
Published in Frontiers in immunology (2023)
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RNA exosome drives early B cell development via noncoding RNA processing mechanisms
Laffleur, Brice, Batista, Carolina R, Zhang, Wanwei, Lim, Junghyun, Yang, Biao, Rossille, Delphine, Wu, Lijing, Estrella, Jerson, Rothschild, Gerson, Pefanis, Evangelos, Basu, Uttiya
Published in Science immunology (03.06.2022)
Published in Science immunology (03.06.2022)
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Noncoding RNA transcription alters chromosomal topology to promote isotype-specific class switch recombination
Rothschild, Gerson, Zhang, Wanwei, Lim, Junghyun, Giri, Pankaj Kumar, Laffleur, Brice, Chen, Yiyun, Fang, Mingyan, Chen, Yuling, Nair, Lekha, Liu, Zhi-Ping, Deng, Haiteng, Hammarström, Lennart, Wang, Jiguang, Basu, Uttiya
Published in Science immunology (07.02.2020)
Published in Science immunology (07.02.2020)
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Effects of senataxin and RNA exosome on B-cell chromosomal integrity
Kazadi, David, Lim, Junghyun, Rothschild, Gerson, Grinstein, Veronika, Laffleur, Brice, Becherel, Olivier, Lavin, Martin J., Basu, Uttiya
Published in Heliyon (01.03.2020)
Published in Heliyon (01.03.2020)
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Anti-CD20 IgA can protect mice against lymphoma development: evaluation of the direct impact of IgA and cytotoxic effector recruitment on CD20 target cells
PASCAL, Virginie, LAFFLEUR, Brice, COGNE, Michel, DEBIN, Arnaud, CUVILLIER, Armelle, EGMOND, Marjolein Van, DROCOURT, Daniel, IMBERTIE, Laurent, PANGAULT, Céline, TARTE, Karin, TIRABY, Gerard
Published in Haematologica (Roma) (01.11.2012)
Published in Haematologica (Roma) (01.11.2012)
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AID-induced remodeling of immunoglobulin genes and B cell fate
Laffleur, Brice, Denis-Lagache, Nicolas, Péron, Sophie, Sirac, Christophe, Moreau, Jeanne, Cogné, Michel
Published in Oncotarget (15.03.2014)
Published in Oncotarget (15.03.2014)
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RNA processing mechanisms contribute to genome organization and stability in B cells
Miglierina, Emma, Ordanoska, Delfina, Le Noir, Sandrine, Laffleur, Brice
Published in Oncogene (23.02.2024)
Published in Oncogene (23.02.2024)
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