Ligand association rates to the inner-variable-domain of a dual-variable-domain immunoglobulin are significantly impacted by linker design
DiGiammarino, Enrico L., Harlan, John E., Walter, Karl A., Ladror, Uri S., Edalji, Rohinton P., Hutchins, Charles W., Lake, Marc R., Greischar, Amy J., Liu, Junjian, Ghayur, Tariq, Jakob, Clarissa G.
Published in mAbs (01.09.2011)
Published in mAbs (01.09.2011)
Get full text
Journal Article
Iniparib Nonselectively Modifies Cysteine-Containing Proteins in Tumor Cells and Is Not a Bona Fide PARP Inhibitor
XUESONG LIU, YAN SHI, XU, Allison J, LAYER, Ramesh, HARLAN, John E, SOLOMON, Larry R, DONAWHO, Cherrie K, PENNING, Thomas D, JOHNSON, Eric F, SHOEMAKER, Alexander R, MAAG, David X, PALMA, Joann P, PATTERSON, Melanie J, ELLIS, Paul A, SURBER, Bruce W, READY, Damien B, SONI, Niru B, LADROR, Uri S
Published in Clinical cancer research (15.01.2012)
Published in Clinical cancer research (15.01.2012)
Get full text
Journal Article
Toxicological Evaluation of Thiol-Reactive Compounds Identified Using a La Assay To Detect Reactive Molecules by Nuclear Magnetic Resonance
Huth, Jeffrey R, Song, Danying, Mendoza, Renaldo R, Black-Schaefer, Candice L, Mack, Jamey C, Dorwin, Sarah A, Ladror, Uri S, Severin, Jean M, Walter, Karl A, Bartley, Diane M, Hajduk, Philip J
Published in Chemical research in toxicology (01.12.2007)
Published in Chemical research in toxicology (01.12.2007)
Get full text
Journal Article
The pyrophosphate-dependent phosphofructokinase of the protist, Trichomonas vaginalis, and the evolutionary relationships of protist phosphofructokinases
Mertens, E, Ladror, U S, Lee, J A, Miretsky, A, Morris, A, Rozario, C, Kemp, R G, Müller, M
Published in Journal of molecular evolution (01.12.1998)
Published in Journal of molecular evolution (01.12.1998)
Get full text
Journal Article
Discovery and Design of Novel HSP90 Inhibitors Using Multiple Fragment-based Design Strategies
Huth, Jeffrey R., Park, Chang, Petros, Andrew M., Kunzer, Aaron R., Wendt, Michael D., Wang, Xilu, Lynch, Christopher L., Mack, Jamey C., Swift, Kerry M., Judge, Russell A., Chen, Jun, Richardson, Paul L., Jin, Sha, Tahir, Stephen K., Matayoshi, Edward D., Dorwin, Sarah A., Ladror, Uri S., Severin, Jean M., Walter, Karl A., Bartley, Diane M., Fesik, Stephen W., Elmore, Steven W., Hajduk, Philip J.
Published in Chemical biology & drug design (01.07.2007)
Published in Chemical biology & drug design (01.07.2007)
Get full text
Journal Article
Crystal Structure of ErmC‘, an rRNA Methyltransferase Which Mediates Antibiotic Resistance in Bacteria
Bussiere, Dirksen E, Muchmore, Steven W, Dealwis, Christopher G, Schluckebier, Gerd, Nienaber, Vicki L, Edalji, Rohinton P, Walter, Karl A, Ladror, Uri S, Holzman, Thomas F, Abad-Zapatero, Cele
Published in Biochemistry (Easton) (19.05.1998)
Published in Biochemistry (Easton) (19.05.1998)
Get full text
Journal Article
A highly potent and selective farnesyltransferase inhibitor ABT-100 in preclinical studies
Gu, Wen-Zhen, Joseph, Ingrid, Wang, Yi-Chun, Frost, David, Sullivan, Gerard M, Wang, Le, Lin, Nan-Horng, Cohen, Jerry, Stoll, Vincent S, Jakob, Clarissa G, Muchmore, Steven W, Harlan, John E, Holzman, Tom, Walten, Karl A, Ladror, Uri S, Anderson, Mark G, Kroeger, Paul, Rodriguez, Luis E, Jarvis, Kenneth P, Ferguson, Debra, Marsh, Kennan, Ng, Shichung, Rosenberg, Saul H, Sham, Hing L, Zhang, Haiying
Published in Anti-cancer drugs (01.11.2005)
Published in Anti-cancer drugs (01.11.2005)
Get more information
Journal Article
Abstract 2783: Empowering therapeutic monoclonal antibodies with IFN-alpha for cancer immunotherapy
Guo, Jun, Xiao, Yu, Lyer, Ramesh B., Lake, Marc R., Ladror, Uri S., Lu, Xin, Pappano, Bill, Harlan, John E., Tomlinson, Medha J., Bukofzer, Gail T., Donawho, Cherrie K., Shoemaker, Alexander R., Huang, Tzu-Hsuan
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Get full text
Journal Article
Cleavage at the amino and carboxyl termini of Alzheimer's amyloid-beta by cathepsin D
LADROR, U. S, SNYDER, S. W, WANG, G. T, HOLZMAN, T. F, KRAFFT, G. A
Published in The Journal of biological chemistry (15.07.1994)
Published in The Journal of biological chemistry (15.07.1994)
Get full text
Journal Article
Domain structure analysis of elongation factor‐3 from saccharomyces cerevisiae by limited proteolysis and differential scanning calorimetry
Ladror, Uri S., Egan, David A., Snyder, Seth W., Capobianco, John O., Goldman, Robert C., Dorwin, Sarah A., Johnson, Robert W., Edalji, Rohinton, Sarthy, Aparna V., Mcgonigal, Tom, Walter, Karl A., Holzman, Thomas F.
Published in Protein science (01.12.1998)
Published in Protein science (01.12.1998)
Get full text
Journal Article
Cathepsin D from Alzheimer's-Diseased and Normal Brains
Kohnken, Russell E., Ladror, Uri S., Wang, Gary T., Holznan, Thomas F., Miller, Barney E., Krafft, Grant A.
Published in Experimental neurology (01.06.1995)
Published in Experimental neurology (01.06.1995)
Get full text
Journal Article
Evidence against a role for the Kunitz domain in amyloidogenic and secretory processing of the amyloid precursor protein
Ladror, U S, Kohnken, R E, Wang, G T, Manelli, A M, Frail, D E, Klein, W L, Holzman, T F, Krafft, G A
Published in Journal of neurochemistry (01.12.1994)
Published in Journal of neurochemistry (01.12.1994)
Get more information
Journal Article
Spinach cytosolic fructose‐1,6‐bisphosphatase
LADROR, Uri S., LATSHAW, Steven P., MARCUS, Frank
Published in European journal of biochemistry (01.04.1990)
Published in European journal of biochemistry (01.04.1990)
Get full text
Journal Article
Centrifugally-enhanced method of determining ligand/target affinity
HARLAN JOHN ERIC, TANG QING, BUKO ALEXANDER M, LADROR URI S, SOLOMON LARRY RICHARD, HOLZMAN THOMAS F, EGAN DAVID A
Year of Publication 07.08.2003
Get full text
Year of Publication 07.08.2003
Patent