Whole genome sequencing of metastatic colorectal cancer reveals prior treatment effects and specific metastasis features
Mendelaar, Pauline A. J., Smid, Marcel, van Riet, Job, Angus, Lindsay, Labots, Mariette, Steeghs, Neeltje, Hendriks, Mathijs P., Cirkel, Geert A., van Rooijen, Johan M., Ten Tije, Albert J., Lolkema, Martijn P., Cuppen, Edwin, Sleijfer, Stefan, Martens, John W. M., Wilting, Saskia M.
Published in Nature communications (25.01.2021)
Published in Nature communications (25.01.2021)
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Reducing renal function assessment prior to platinum-based chemotherapy: a real-world evaluation
Van der Gaag, Suzanne, Labots, Mariette, Swart, Eleonora L, Crul, Mirjam
Published in Acta oncologica (10.04.2024)
Published in Acta oncologica (10.04.2024)
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Lysosomal Sequestration of Sunitinib: A Novel Mechanism of Drug Resistance
GOTINK, Kristy J, BROXTERMAN, Henk J, GRIFFIOEN, Arjan W, ASSARAF, Yehuda G, PILI, Roberto, PETERS, Godefridus J, VERHEUL, Henk M. W, LABOTS, Mariette, DE HAAS, Richard R, DEKKER, Henk, HONEYWELL, Richard J, RUDEK, Michelle A, BEEREPOOT, Laurens V, MUSTERS, René J, JANSEN, Gerrit
Published in Clinical cancer research (01.12.2011)
Published in Clinical cancer research (01.12.2011)
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INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases
Beekhof, Robin, van Alphen, Carolien, Henneman, Alex A, Knol, Jaco C, Pham, Thang V, Rolfs, Frank, Labots, Mariette, Henneberry, Evan, Le Large, Tessa YS, de Haas, Richard R, Piersma, Sander R, Vurchio, Valentina, Bertotti, Andrea, Trusolino, Livio, Verheul, Henk MW, Jimenez, Connie R
Published in Molecular systems biology (01.04.2019)
Published in Molecular systems biology (01.04.2019)
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Author Correction: Whole genome sequencing of metastatic colorectal cancer reveals prior treatment effects and specific metastasis features
Mendelaar, Pauline A. J., Smid, Marcel, van Riet, Job, Angus, Lindsay, Labots, Mariette, Steeghs, Neeltje, Hendriks, Mathijs P., Cirkel, Geert A., van Rooijen, Johan M., Ten Tije, Albert J., Lolkema, Martijn P., Cuppen, Edwin, Sleijfer, Stefan, Martens, John W. M., Wilting, Saskia M.
Published in Nature communications (26.05.2021)
Published in Nature communications (26.05.2021)
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Therapeutic drug monitoring to individualize the dosing of pazopanib: a pharmacokinetic feasibility study
de Wit, Djoeke, van Erp, Nielka P, den Hartigh, Jan, Wolterbeek, Ron, den Hollander-van Deursen, Margret, Labots, Mariëtte, Guchelaar, Henk-Jan, Verheul, Henk M, Gelderblom, Hans
Published in Therapeutic drug monitoring (01.06.2015)
Published in Therapeutic drug monitoring (01.06.2015)
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Effect of food on the pharmacokinetics of the WEE1 inhibitor adavosertib (AZD1775) in patients with advanced solid tumors
Någård, Mats, Ah-See, Mei-Lin, So, Karen, Vermunt, Marit, Thistlethwaite, Fiona, Labots, Mariette, Roxburgh, Patricia, Ravaud, Alain, Campone, Mario, Valkenburg-van Iersel, Liselot, Ottesen, Lone, Li, Yan, Mugundu, Ganesh
Published in Cancer chemotherapy and pharmacology (01.07.2020)
Published in Cancer chemotherapy and pharmacology (01.07.2020)
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Multi-omic analysis identifies hypoalbuminemia as independent biomarker of poor outcome upon PD-1 blockade in metastatic melanoma
Leek, Lindsay V. M., Notohardjo, Jessica C. L., de Joode, Karlijn, Velker, Eline L., Haanen, John B. A. G., Suijkerbuijk, Karijn P. M., Aarts, Maureen J. B., de Groot, Jan Willem B., Kapiteijn, Ellen, van den Berkmortel, Franchette W. P. J., Westgeest, Hans M., de Gruijl, Tanja D., Retel, Valesca P., Cuppen, Edwin, van der Veldt, Astrid A. M., Labots, Mariette, Voest, Emile E., van de Haar, Joris, van den Eertwegh, Alfons J. M.
Published in Scientific reports (16.05.2024)
Published in Scientific reports (16.05.2024)
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Efficacy, safety and biomarker analysis of durvalumab in patients with mismatch-repair deficient or microsatellite instability-high solid tumours
Geurts, Birgit S, Battaglia, Thomas W, van Berge Henegouwen, J Maxime, Zeverijn, Laurien J, de Wit, Gijs F, Hoes, Louisa R, van der Wijngaart, Hanneke, van der Noort, Vincent, Roepman, Paul, de Leng, Wendy W J, Jansen, Anne M L, Opdam, Frans L, de Jonge, Maja J A, Cirkel, Geert A, Labots, Mariette, Hoeben, Ann, Kerver, Emile D, Bins, Adriaan D, Erdkamp, Frans G L, van Rooijen, Johan M, Houtsma, Danny, Hendriks, Mathijs P, de Groot, Jan-Willem B, Verheul, Henk M W, Gelderblom, Hans, Voest, Emile E
Published in BMC cancer (04.03.2023)
Published in BMC cancer (04.03.2023)
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Feasibility of label-free phosphoproteomics and application to base-line signaling of colorectal cancer cell lines
Piersma, Sander R., Knol, Jaco C., de Reus, Inge, Labots, Mariette, Sampadi, Bharath K., Pham, Thang V., Ishihama, Yasushi, Verheul, Henk M.W., Jimenez, Connie R.
Published in Journal of proteomics (08.09.2015)
Published in Journal of proteomics (08.09.2015)
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Identifying somatic changes in drug transporters using whole genome and transcriptome sequencing data of advanced tumors
van de Geer, Wesley S., Mathijssen, Ron H.J., van Riet, Job, Steeghs, Neeltje, Labots, Mariette, van Herpen, Carla, Devriese, Lot A., Tjan-Heijnen, Vivianne C.G., Voest, Emile E., Sleijfer, Stefan, Martens, John W.M., Cuppen, Edwin, van de Werken, Harmen J.G., Bins, Sander
Published in Biomedicine & pharmacotherapy (01.03.2023)
Published in Biomedicine & pharmacotherapy (01.03.2023)
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Genomic landscape of metastatic colorectal cancer
Haan, Josien C., Labots, Mariette, Rausch, Christian, Koopman, Miriam, Tol, Jolien, Mekenkamp, Leonie J. M., van de Wiel, Mark A., Israeli, Danielle, van Essen, Hendrik F., van Grieken, Nicole C. T., Voorham, Quirinus J. M., Bosch, Linda J. W., Qu, Xueping, Kabbarah, Omar, Verheul, Henk M. W., Nagtegaal, Iris D., Punt, Cornelis J. A., Ylstra, Bauke, Meijer, Gerrit A.
Published in Nature communications (14.11.2014)
Published in Nature communications (14.11.2014)
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Evaluation of different phospho-tyrosine antibodies for label-free phosphoproteomics
van der Mijn, Johannes C., Labots, Mariette, Piersma, Sander R., Pham, Thang V., Knol, Jaco C., Broxterman, Henk J., Verheul, Henk M., Jiménez, Connie R.
Published in Journal of proteomics (08.09.2015)
Published in Journal of proteomics (08.09.2015)
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Phosphotyrosine-based-phosphoproteomics scaled-down to biopsy level for analysis of individual tumor biology and treatment selection
Labots, Mariette, van der Mijn, Johannes C., Beekhof, Robin, Piersma, Sander R., de Goeij-de Haas, Richard R., Pham, Thang V., Knol, Jaco C., Dekker, Henk, van Grieken, Nicole C.T., Verheul, Henk M.W., Jiménez, Connie R.
Published in Journal of proteomics (06.06.2017)
Published in Journal of proteomics (06.06.2017)
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INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases
Beekhof, Robin, Alphen, Carolien, Henneman, Alex A, Knol, Jaco C, Pham, Thang V, Rolfs, Frank, Labots, Mariette, Henneberry, Evan, Le Large, Tessa YS, Haas, Richard R, Piersma, Sander R, Vurchio, Valentina, Bertotti, Andrea, Trusolino, Livio, Verheul, Henk MW, Jimenez, Connie R
Published in Molecular systems biology (01.05.2019)
Published in Molecular systems biology (01.05.2019)
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Advancing wide implementation of precision oncology: A liquid nitrogen‐free snap freezer preserves molecular profiles of biological samples
Wijngaart, Hanneke, Jagga, Sahil, Dekker, Henk, Goeij, Richard, Piersma, Sander R., Pham, Thang V., Knol, Jaco C., Zonderhuis, Babs M., Holland, Harry J., Jiménez, Connie R., Verheul, Henk M. W., Vanapalli, Srinivas, Labots, Mariette
Published in Cancer medicine (Malden, MA) (01.05.2023)
Published in Cancer medicine (Malden, MA) (01.05.2023)
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Evaluation of a tyrosine kinase peptide microarray for tyrosine kinase inhibitor therapy selection in cancer
Labots, Mariette, Gotink, Kristy J, Dekker, Henk, Azijli, Kaamar, van der Mijn, Johannes C, Huijts, Charlotte M, Piersma, Sander R, Jiménez, Connie R, Verheul, Henk M W
Published in Experimental & molecular medicine (16.12.2016)
Published in Experimental & molecular medicine (16.12.2016)
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Pan-cancer whole-genome analyses of metastatic solid tumours
Priestley, Peter, Baber, Jonathan, Lolkema, Martijn P., Steeghs, Neeltje, de Bruijn, Ewart, Shale, Charles, Duyvesteyn, Korneel, Haidari, Susan, van Hoeck, Arne, Onstenk, Wendy, Roepman, Paul, Voda, Mircea, Bloemendal, Haiko J., Tjan-Heijnen, Vivianne C. G., van Herpen, Carla M. L., Labots, Mariette, Witteveen, Petronella O., Smit, Egbert F., Sleijfer, Stefan, Voest, Emile E., Cuppen, Edwin
Published in Nature (London) (01.11.2019)
Published in Nature (London) (01.11.2019)
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The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies
Angus, Lindsay, Smid, Marcel, Wilting, Saskia M., van Riet, Job, Van Hoeck, Arne, Nguyen, Luan, Nik-Zainal, Serena, Steenbruggen, Tessa G., Tjan-Heijnen, Vivianne C. G., Labots, Mariette, van Riel, Johanna M. G. H., Bloemendal, Haiko J., Steeghs, Neeltje, Lolkema, Martijn P., Voest, Emile E., van de Werken, Harmen J. G., Jager, Agnes, Cuppen, Edwin, Sleijfer, Stefan, Martens, John W. M.
Published in Nature genetics (01.10.2019)
Published in Nature genetics (01.10.2019)
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Frequency of measuring body weight in (sub)populations of patients with cancer treated with chemotherapy
Kemps, Shirley, Soleyman, Mostafa, Huls, Harmen, Labots, Mariette, Crul, Mirjam
Published in European journal of hospital pharmacy. Science and practice (01.03.2024)
Published in European journal of hospital pharmacy. Science and practice (01.03.2024)
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