First crystal structures of 1-deoxy-d-xylulose 5-phosphate synthase (DXPS) from Mycobacterium tuberculosis indicate a distinct mechanism of intermediate stabilization
Gierse, Robin M., Oerlemans, Rick, Reddem, Eswar R., Gawriljuk, Victor O., Alhayek, Alaa, Baitinger, Dominik, Jakobi, Harald, Laber, Bernd, Lange, Gudrun, Hirsch, Anna K. H., Groves, Matthew R.
Published in Scientific reports (04.05.2022)
Published in Scientific reports (04.05.2022)
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Journal Article
Mechanism and structure based design of inhibitors of AMP and adenosine deaminase
Lindell, Stephen D., Maechling, Simon, Klein, Robert, Freigang, Jörg, Laber, Bernd, Blanazs, Lisa, Leonhardt, Merisa, Haupt, Susanne, Petry, Thomas, Sabina, Richard L.
Published in Bioorganic & medicinal chemistry (01.08.2021)
Published in Bioorganic & medicinal chemistry (01.08.2021)
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Journal Article
Synthesis and biological profile of 2,3-dihydro[1,3]thiazolo[4,5- b ]pyridines, a novel class of acyl-ACP thioesterase inhibitors
Frackenpohl, Jens, Barber, David M, Bojack, Guido, Bollenbach-Wahl, Birgit, Braun, Ralf, Getachew, Rahel, Hohmann, Sabine, Ko, Kwang-Yoon, Kurowski, Karoline, Laber, Bernd, Mattison, Rebecca L, Müller, Thomas, Reingruber, Anna M, Schmutzler, Dirk, Svejda, Andrea
Published in Beilstein journal of organic chemistry (01.03.2024)
Published in Beilstein journal of organic chemistry (01.03.2024)
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Journal Article
Vitamin B6 biosynthesis: formation of pyridoxine 5′‐phosphate from 4‐(phosphohydroxy)‐l‐threonine and 1‐deoxy‐d‐xylulose‐5‐phosphate by PdxA and PdxJ protein
Laber, Bernd, Maurer, Wolfgang, Scharf, Sandra, Stepusin, Karin, Schmidt, Frank S
Published in FEBS letters (16.04.1999)
Published in FEBS letters (16.04.1999)
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Journal Article
The Three-Dimensional Structure of Cystathionine β-Lyase from Arabidopsis and Its Substrate Specificity
Ulrike Breitinger, Clausen, Tim, Stephan Ehlert, Huber, Robert, Bernd Laber, Schmidt, Frank, Ehmke Pohl, Messerschmidt, Albrecht
Published in Plant physiology (Bethesda) (01.06.2001)
Published in Plant physiology (Bethesda) (01.06.2001)
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Journal Article
Structure and Function of Threonine Synthase from Yeast
Garrido-Franco, Marta, Ehlert, Stephan, Messerschmidt, Albrecht, Marinković, Snežan, Huber, Robert, Laber, Bernd, Bourenkov, Gleb P., Clausen, Tim
Published in The Journal of biological chemistry (05.04.2002)
Published in The Journal of biological chemistry (05.04.2002)
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Journal Article
Structural Basis for the Function of Pyridoxine 5′-Phosphate Synthase
Franco, Marta Garrido, Laber, Bernd, Huber, Robert, Clausen, Tim
Published in Structure (London) (07.03.2001)
Published in Structure (London) (07.03.2001)
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Journal Article
Investigations into Simplified Analogues of the Herbicidal Natural Product (+)‐Cornexistin
Steinborn, Christian, Tancredi, Aldo, Habiger, Christoph, Diederich, Christina, Kramer, Jan, Reingruber, Anna M., Laber, Bernd, Freigang, Jörg, Lange, Gudrun, Schmutzler, Dirk, Machettira, Anu, Besong, Gilbert, Magauer, Thomas, Barber, David M.
Published in Chemistry : a European journal (11.07.2023)
Published in Chemistry : a European journal (11.07.2023)
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Journal Article
The novel herbicide icafolin-methyl is a plant-specific inhibitor of tubulin polymerization
Haaf, Klaus-Bernhard, Peters, Olaf, Laber, Bernd, Lange, Gudrun, Gatzweiler, Elmar, Geibel, Sven, Passon, Daniel, Endler, Anne, Lange, Sylvia, Kahlau, Sabine, Eroschenko, Tatjana, Waldraff, Petra, Lümmen, Peter
Published in Pest management science (19.09.2024)
Published in Pest management science (19.09.2024)
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Journal Article
Scaffold hopping approaches for the exploration of herbicidally active compounds inhibiting Acyl-ACP Thioesterase
Fahrenhorst-Jones, Tyler, Lee, Stephanie, Bollenbach-Wahl, Birgit, Bojack, Guido, Braun, Ralf, Frackenpohl, Jens, Heinemann, Ines, Laber, Bernd, Lange, Gudrun, Peters, Olaf, Reingruber, Anna M, Schmutzler, Dirk, Barber, David M
Published in Pest management science (19.08.2024)
Published in Pest management science (19.08.2024)
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Journal Article
Synthesis and biological profile of substituted hexahydrofuro[3,4-b]furans, a novel class of bicyclic acyl-acyl carrier protein (ACP) thioesterase inhibitors
Ahrens, Hartmut, Barber, David M, Bojack, Guido, Bollenbach-Wahl, Birgit, Churchman, Luke, Getachew, Rahel, Helmke, Hendrik, Hohmann, Sabine, Laber, Bernd, Lange, Gudrun, Rees, Shaun, Reingruber, Anna M, Schmutzler, Dirk, Frackenpohl, Jens
Published in Pest management science (06.08.2024)
Published in Pest management science (06.08.2024)
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Journal Article
Identification of a 1-deoxy-D-xylulose-5-phosphate synthase (DXS) mutant with improved crystallographic properties
Gierse, Robin M., Reddem, Eswar R., Alhayek, Alaa, Baitinger, Dominik, Hamid, Zhoor, Jakobi, Harald, Laber, Bernd, Lange, Gudrun, Hirsch, Anna K.H., Groves, Matthew R.
Published in Biochemical and biophysical research communications (05.02.2021)
Published in Biochemical and biophysical research communications (05.02.2021)
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Journal Article
A Study in Scaffold Hopping: Discovery and Optimization of Thiazolopyridines as Potent Herbicides That Inhibit Acyl-ACP Thioesterase
Abel, Steven A. G., Alnafta, Neanne, Asmus, Elisabeth, Bollenbach-Wahl, Birgit, Braun, Ralf, Dittgen, Jan, Endler, Anne, Frackenpohl, Jens, Freigang, Joerg, Gatzweiler, Elmar, Heinemann, Ines, Helmke, Hendrik, Laber, Bernd, Lange, Gudrun, Machettira, Anu, Mcarthur, Gillian, Mueller, Thomas, Odaybat, Magdalena, Reingruber, Anna M., Roth, Sina, Rosinger, Christopher H., Schmutzler, Dirk, Schulte, Wolfgang, Stoppel, Rhea, Tiebes, Joerg, Volpin, Giulio, Barber, David M.
Published in Journal of agricultural and food chemistry (29.11.2023)
Published in Journal of agricultural and food chemistry (29.11.2023)
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Journal Article
Aclonifen targets solanesyl diphosphate synthase, representing a novel mode of action for herbicides
Kahlau, Sabine, Schröder, Florian, Freigang, Jörg, Laber, Bernd, Lange, Gudrun, Passon, Daniel, Kleeßen, Sabrina, Lohse, Marc, Schulz, Arno, von Koskull‐Döring, Pascal, Klie, Sebastian, Gille, Sascha
Published in Pest management science (01.10.2020)
Published in Pest management science (01.10.2020)
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Journal Article
Investigation of acetyl-CoA carboxylase-inhibiting herbicides that exhibit soybean crop selectivity
Lee, Stephanie, Payne, China, Rees, Shaun, Ahrens, Hartmut, Arve, Lars, Asmus, Elisabeth, Bojack, Guido, Arsequell, Estel la Buscató, Gatzweiler, Elmar, Helmke, Hendrik, Kallus, Christopher, Laber, Bernd, Lange, Gudrun, Lehr, Stefan, Menne, Hubert, Rosinger, Christopher H, Schulte, Wolfgang, Sommer, Kai, Barber, David M
Published in Pest management science (12.10.2024)
Published in Pest management science (12.10.2024)
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Journal Article
Photochemical transformation of a cellulose biosynthesis inhibitor into phytoene desaturase inhibitors
Wakeham, Matthew C.L., Lim, Zelong, Lindell, Stephen D., Laber, Bernd, Hain, Rüdiger, Jeschke, Peter, Hey, Daniel
Published in Bioorganic & medicinal chemistry letters (15.10.2021)
Published in Bioorganic & medicinal chemistry letters (15.10.2021)
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Journal Article
Repression of Acetolactate Synthase Activity through Antisense Inhibition: Molecular and Biochemical Analysis of Transgenic Potato (Solanum tuberosum L. cv Désirée) Plants
Höfgen, Rainer, Bernd Laber, Schüttke, Iris, Ann-Kristin Klonus, Wolfgang Streber, Pohlenz, Hans-Dieter
Published in Plant physiology (Bethesda) (01.02.1995)
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Published in Plant physiology (Bethesda) (01.02.1995)
Journal Article
Discovery and Optimization of Spirocyclic Lactams that Inhibit Acyl-ACP Thioesterase
Asmus, Elisabeth, Barber, David M, Bojack, Guido, Bollenbach-Wahl, Birgit, Brown, Ronald W, Döller, Uwe, Freigang, Jörg, Gatzweiler, Elmar, Getachew, Rahel, Heinemann, Ines, Hohmann, Sabine, Ko, Kwang-Yoon, Laber, Bernd, Lange, Gudrun, Mattison, Rebecca L, Minn, Klemens, Müller, Thomas, Petry, Thomas, Reingruber, Anna M, Schmutzler, Dirk, Svejda, Andrea, Frackenpohl, Jens
Published in Pest management science (26.02.2024)
Published in Pest management science (26.02.2024)
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