A structural exposé of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop
Wang, Huanchen, Perera, Lalith, Jork, Nikolaus, Zong, Guangning, Riley, Andrew M., Potter, Barry V. L., Jessen, Henning J., Shears, Stephen B.
Published in Nature communications (25.04.2022)
Published in Nature communications (25.04.2022)
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Substrate promiscuity of inositol 1,4,5-trisphosphate kinase driven by structurally-modified ligands and active site plasticity
Márquez-Moñino, María Ángeles, Ortega-García, Raquel, Whitfield, Hayley, Riley, Andrew M., Infantes, Lourdes, Garrett, Shane W., Shipton, Megan L., Brearley, Charles A., Potter, Barry V. L., González, Beatriz
Published in Nature communications (19.02.2024)
Published in Nature communications (19.02.2024)
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Structure–Activity Relationship of Adenosine 5′-diphosphoribose at the Transient Receptor Potential Melastatin 2 (TRPM2) Channel: Rational Design of Antagonists
Moreau, Christelle, Kirchberger, Tanja, Swarbrick, Joanna M, Bartlett, Stephen J, Fliegert, Ralf, Yorgan, Timur, Bauche, Andreas, Harneit, Angelika, Guse, Andreas H, Potter, Barry V. L
Published in Journal of medicinal chemistry (27.12.2013)
Published in Journal of medicinal chemistry (27.12.2013)
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Cell Fate following Irradiation of MDA-MB-231 and MCF-7 Breast Cancer Cells Pre-Exposed to the Tetrahydroisoquinoline Sulfamate Microtubule Disruptor STX3451
Hargrave, Scott D, Joubert, Anna M, Potter, Barry V L, Dohle, Wolfgang, Marais, Sumari, Mercier, Anne E
Published in Molecules (Basel, Switzerland) (14.06.2022)
Published in Molecules (Basel, Switzerland) (14.06.2022)
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Cyclic Adenosine 5′-Diphosphate Ribose Analogs without a “Southern” Ribose Inhibit ADP-ribosyl Cyclase–Hydrolase CD38
Swarbrick, Joanna M, Graeff, Richard, Zhang, Hongmin, Thomas, Mark P, Hao, Quan, Potter, Barry V. L
Published in Journal of medicinal chemistry (23.10.2014)
Published in Journal of medicinal chemistry (23.10.2014)
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Accessing simply-substituted 4-hydroxytetrahydroisoquinolines via Pomeranz-Fritsch-Bobbitt reaction with non-activated and moderately-activated systems
Mottinelli, Marco, Leese, Mathew P, Potter, Barry V L
Published in Beilstein journal of organic chemistry (06.09.2017)
Published in Beilstein journal of organic chemistry (06.09.2017)
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Novel Anti-Acanthamoebic Activities of Irosustat and STX140 and Their Nanoformulations
Siddiqui, Ruqaiyyah, Rawas-Qalaji, Mutasem, El-Gamal, Mohammed I, Sajeev, Sreedevi, Jagal, Jayalakshmi, Zaraei, Seyed-Omar, Sbenati, Rawan M, Anbar, Hanan S, Dohle, Wolfgang, Potter, Barry V L, Khan, Naveed Ahmed
Published in Antibiotics (Basel) (01.03.2023)
Published in Antibiotics (Basel) (01.03.2023)
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CD38 Structure-Based Inhibitor Design Using the N1-Cyclic Inosine 5'-Diphosphate Ribose Template
Moreau, Christelle, Liu, Qun, Graeff, Richard, Wagner, Gerd K, Thomas, Mark P, Swarbrick, Joanna M, Shuto, Satoshi, Lee, Hon Cheung, Hao, Quan, Potter, Barry V L
Published in PloS one (19.06.2013)
Published in PloS one (19.06.2013)
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'Click cyclic ADP-ribose': a neutral second messenger mimic
Swarbrick, Joanna M., Graeff, Richard, Garnham, Clive, Thomas, Mark P., Galione, Antony, Potter, Barry V. L.
Published in Chemical communications (Cambridge, England) (01.01.2014)
Published in Chemical communications (Cambridge, England) (01.01.2014)
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Design and Synthesis of Cyclic ADP-4-Thioribose as a Stable Equivalent of Cyclic ADP-Ribose, a Calcium Ion-Mobilizing Second Messenger
Tsuzuki, Takayoshi, Sakaguchi, Natsumi, Kudoh, Takashi, Takano, Satoshi, Uehara, Masato, Murayama, Takashi, Sakurai, Takashi, Hashii, Minako, Higashida, Haruhiro, Weber, Karin, Guse, Andreas H., Kameda, Tomoshi, Hirokawa, Takatsugu, Kumaki, Yasuhiro, Potter, Barry V. L., Fukuda, Hayato, Arisawa, Mitsuhiro, Shuto, Satoshi
Published in Angewandte Chemie International Edition (24.06.2013)
Published in Angewandte Chemie International Edition (24.06.2013)
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C‑3- and C‑4-Substituted Bicyclic Coumarin Sulfamates as Potent Steroid Sulfatase Inhibitors
Ganeshapillai, Dharshini, Woo, L. W. Lawrence, Thomas, Mark P, Purohit, Atul, Potter, Barry V. L
Published in ACS omega (30.09.2018)
Published in ACS omega (30.09.2018)
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Quinazolinone-Based Anticancer Agents: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Tubulin Co-crystal Structure
Dohle, Wolfgang, Jourdan, Fabrice L, Menchon, Grégory, Prota, Andrea E, Foster, Paul A, Mannion, Pascoe, Hamel, Ernest, Thomas, Mark P, Kasprzyk, Philip G, Ferrandis, Eric, Steinmetz, Michel O, Leese, Mathew P, Potter, Barry V. L
Published in Journal of medicinal chemistry (08.02.2018)
Published in Journal of medicinal chemistry (08.02.2018)
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2-Substituted Estradiol Bis-sulfamates, Multitargeted Antitumor Agents: Synthesis, In Vitro SAR, Protein Crystallography, and In Vivo Activity
Leese, Mathew P, Leblond, Bertrand, Smith, Andrew, Newman, Simon P, Di Fiore, Anna, De Simone, Giuseppina, Supuran, Claudiu T, Purohit, Atul, Reed, Michael J, Potter, Barry V. L
Published in Journal of medicinal chemistry (28.12.2006)
Published in Journal of medicinal chemistry (28.12.2006)
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Insights into the activation mechanism of class I HDAC complexes by inositol phosphates
Watson, Peter J., Millard, Christopher J., Riley, Andrew M., Robertson, Naomi S., Wright, Lyndsey C., Godage, Himali Y., Cowley, Shaun M., Jamieson, Andrew G., Potter, Barry V. L., Schwabe, John W. R.
Published in Nature communications (25.04.2016)
Published in Nature communications (25.04.2016)
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