A chemocentric approach to the identification of cancer targets
Flachner, Beáta, Lörincz, Zsolt, Carotti, Angelo, Nicolotti, Orazio, Kuchipudi, Praveena, Remez, Nikita, Sanz, Ferran, Tóvári, József, Szabó, Miklós J, Bertók, Béla, Cseh, Sándor, Mestres, Jordi, Dormán, György
Published in PloS one (25.04.2012)
Published in PloS one (25.04.2012)
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Journal Article
Development of Continuous Additive-Controlled MSMPR Crystallization by DoE-Based Batch Experiments
Stoffán, György Nimród, Lőrincz, Zsolt, Pusztai, Éva, Madarász, Lajos, Tacsi, Kornélia, Marosi, György, Pataki, Hajnalka
Published in Industrial & engineering chemistry research (07.08.2024)
Published in Industrial & engineering chemistry research (07.08.2024)
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Journal Article
Inhibition of the LOX enzyme family members with old and new ligands. Selectivity analysis revisited
Hajdú, István, Kardos, József, Major, Balázs, Fabó, Gabriella, Lőrincz, Zsolt, Cseh, Sándor, Dormán, György
Published in Bioorganic & medicinal chemistry letters (01.10.2018)
Published in Bioorganic & medicinal chemistry letters (01.10.2018)
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Journal Article
Dual Inhibitors of AChE and BACE-1 for Reducing Aβ in Alzheimer’s Disease: From In Silico to In Vivo
Stern, Noa, Gacs, Alexandra, Tátrai, Enikő, Flachner, Beáta, Hajdú, István, Dobi, Krisztina, Bágyi, István, Dormán, György, Lőrincz, Zsolt, Cseh, Sándor, Kígyós, Attila, Tóvári, József, Goldblum, Amiram
Published in International journal of molecular sciences (01.11.2022)
Published in International journal of molecular sciences (01.11.2022)
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Journal Article
Rapid Identification of Potential Drug Candidates from Multi-Million Compounds' Repositories. Combination of 2D Similarity Search with 3D Ligand/Structure Based Methods and In Vitro Screening
Szilágyi, Katalin, Flachner, Beáta, Hajdú, István, Szaszkó, Mária, Dobi, Krisztina, Lőrincz, Zsolt, Cseh, Sándor, Dormán, György
Published in Molecules (Basel, Switzerland) (15.09.2021)
Published in Molecules (Basel, Switzerland) (15.09.2021)
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Journal Article
Semisynthetic teicoplanin derivatives with dual antimicrobial activity against SARS-CoV-2 and multiresistant bacteria
Bereczki, Ilona, Vimberg, Vladimir, Lőrincz, Eszter, Papp, Henrietta, Nagy, Lajos, Kéki, Sándor, Batta, Gyula, Mitrović, Ana, Kos, Janko, Zsigmond, Áron, Hajdú, István, Lőrincz, Zsolt, Bajusz, Dávid, Petri, László, Hodek, Jan, Jakab, Ferenc, Keserű, György M., Weber, Jan, Naesens, Lieve, Herczegh, Pál, Borbás, Anikó
Published in Scientific reports (26.09.2022)
Published in Scientific reports (26.09.2022)
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Journal Article
Design and Selection of Novel C1s Inhibitors by In Silico and In Vitro Approaches
Szilágyi, Katalin, Hajdú, István, Flachner, Beáta, Lőrincz, Zsolt, Balczer, Júlia, Gál, Péter, Závodszky, Péter, Pirli, Chiara, Balogh, Balázs, Mándity, István M, Cseh, Sándor, Dormán, György
Published in Molecules (Basel, Switzerland) (09.10.2019)
Published in Molecules (Basel, Switzerland) (09.10.2019)
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Journal Article
Robust Recombinant Expression of Human Placental Ribonuclease Inhibitor in Insect Cells
Flachner, Beáta, Dobi, Krisztina, Benedek, Anett, Cseh, Sándor, Lőrincz, Zsolt, Hajdú, István
Published in Biomolecules (Basel, Switzerland) (08.02.2022)
Published in Biomolecules (Basel, Switzerland) (08.02.2022)
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Journal Article
Combination of 2D/3D ligand-based similarity search in rapid virtual screening from multimillion compound repositories. Selection and biological evaluation of potential PDE4 and PDE5 inhibitors
Dobi, Krisztina, Hajdú, István, Flachner, Beáta, Fabó, Gabriella, Szaszkó, Mária, Bognár, Melinda, Magyar, Csaba, Simon, István, Szisz, Dániel, Lőrincz, Zsolt, Cseh, Sándor, Dormán, György
Published in Molecules (Basel, Switzerland) (28.05.2014)
Published in Molecules (Basel, Switzerland) (28.05.2014)
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Journal Article
Natural Apocarotenoids and Their Synthetic Glycopeptide Conjugates Inhibit SARS-CoV-2 Replication
Bereczki, Ilona, Papp, Henrietta, Kuczmog, Anett, Madai, Mónika, Nagy, Veronika, Agócs, Attila, Batta, Gyula, Milánkovits, Márton, Ostorházi, Eszter, Mitrović, Ana, Kos, Janko, Zsigmond, Áron, Hajdú, István, Lőrincz, Zsolt, Bajusz, Dávid, Keserű, György Miklós, Hodek, Jan, Weber, Jan, Jakab, Ferenc, Herczegh, Pál, Borbás, Anikó
Published in Pharmaceuticals (Basel, Switzerland) (30.10.2021)
Published in Pharmaceuticals (Basel, Switzerland) (30.10.2021)
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Journal Article
Structure-Based Consensus Scoring Scheme for Selecting Class A Aminergic GPCR Fragments
Kelemen, Ádám A, Kiss, Róbert, Ferenczy, György G, Kovács, László, Flachner, Beáta, Lőrincz, Zsolt, Keserű, György M
Published in Journal of chemical information and modeling (22.02.2016)
Published in Journal of chemical information and modeling (22.02.2016)
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Journal Article
RuX: A Novel, Flexible, and Sensitive Mifepristone-Induced Transcriptional Regulation System
Meinzinger, Anne, Zsigmond, Áron, Horváth, Péter, Kellenberger, Alexandra, Paréj, Katalin, Tallone, Tiziano, Flachner, Beáta, Cserhalmi, Marcell, Lőrincz, Zsolt, Cseh, Sándor, Shmerling, Doron
Published in International journal of cell biology (31.10.2023)
Published in International journal of cell biology (31.10.2023)
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Journal Article
Apelin Expression in Human Non-small Cell Lung Cancer: Role in Angiogenesis and Prognosis
Berta, Judit, Kenessey, Istvan, Dobos, Judit, Tovari, Jozsef, Klepetko, Walter, Jan Ankersmit, Hendrik, Hegedus, Balazs, Renyi-Vamos, Ferenc, Varga, Janos, Lorincz, Zsolt, Paku, Sandor, Ostoros, Gyula, Rozsas, Anita, Timar, Jozsef, Dome, Balazs
Published in Journal of thoracic oncology (01.08.2010)
Published in Journal of thoracic oncology (01.08.2010)
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Journal Article
Identification of potential glutaminyl cyclase inhibitors from lead-like libraries by in silico and in vitro fragment-based screening
Szaszkó, Mária, Hajdú, István, Flachner, Beáta, Dobi, Krisztina, Magyar, Csaba, Simon, István, Lőrincz, Zsolt, Kapui, Zoltán, Pázmány, Tamás, Cseh, Sándor, Dormán, György
Published in Molecular diversity (01.02.2017)
Published in Molecular diversity (01.02.2017)
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Journal Article
Monoclonal antibody proteomics: Use of antibody mimotope displaying phages and the relevant synthetic peptides for mAb scouting
Hajdú, István, Flachner, Beáta, Bognár, Melinda, Végh, Barbara M, Dobi, Krisztina, Lőrincz, Zsolt, Lázár, József, Cseh, Sándor, Takács, László, Kurucz, István
Published in Immunology letters (01.08.2014)
Published in Immunology letters (01.08.2014)
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Journal Article
Calcium-dependent Conformational Flexibility of a CUB Domain Controls Activation of the Complement Serine Protease C1r
Major, Balázs, Kardos, József, Kékesi, Katalin Adrienna, Lőrincz, Zsolt, Závodszky, Péter, Gál, Péter
Published in The Journal of biological chemistry (16.04.2010)
Published in The Journal of biological chemistry (16.04.2010)
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Journal Article
One Active C1r Subunit Is Sufficient for the Activity of the Complement C1 Complex: Stabilization of C1r in the Zymogen Form by Point Mutations
Dobo, Jozsef, Gal, Peter, Szilagyi, Katalin, Cseh, Sandor, Lorincz, Zsolt, Schumaker, Verne N, Zavodszky, Peter
Published in The Journal of immunology (1950) (15.01.1999)
Published in The Journal of immunology (1950) (15.01.1999)
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Journal Article
Combination of Pharmacophore Matching, 2D Similarity Search, and In Vitro Biological Assays in the Selection of Potential 5-HT6 Antagonists from Large Commercial Repositories
Dobi, Krisztina, Flachner, Beáta, Pukáncsik, Mária, Máthé, Enikő, Bognár, Melinda, Szaszkó, Mária, Magyar, Csaba, Hajdú, István, Lőrincz, Zsolt, Simon, István, Fülöp, Ferenc, Cseh, Sándor, Dormán, György
Published in Chemical biology & drug design (01.10.2015)
Published in Chemical biology & drug design (01.10.2015)
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Journal Article
Combination of Pharmacophore Matching, 2D Similarity Search, and In Vitro Biological Assays in the Selection of Potential 5‐HT 6 Antagonists from Large Commercial Repositories
Dobi, Krisztina, Flachner, Beáta, Pukáncsik, Mária, Máthé, Enikő, Bognár, Melinda, Szaszkó, Mária, Magyar, Csaba, Hajdú, István, Lőrincz, Zsolt, Simon, István, Fülöp, Ferenc, Cseh, Sándor, Dormán, György
Published in Chemical biology & drug design (01.10.2015)
Published in Chemical biology & drug design (01.10.2015)
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Journal Article
The Cleavage of Two C1s Subunits by a Single Active C1r Reveals Substantial Flexibility of the C1s-C1r-C1r-C1s Tetramer in the C1 Complex
Lorincz, Zsolt, Gal, Peter, Dobo, Jozsef, Cseh, Sandor, Szilagyi, Katalin, Ambrus, Geza, Zavodszky, Peter
Published in The Journal of immunology (1950) (15.08.2000)
Published in The Journal of immunology (1950) (15.08.2000)
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