Structure–Activity Relationship, Pharmacological Characterization, and Molecular Modeling of Noncompetitive Inhibitors of the Betaine/γ-Aminobutyric Acid Transporter 1 (BGT1)
Jørgensen, Lars, Al-Khawaja, Anas, Kickinger, Stefanie, Vogensen, Stine B, Skovgaard-Petersen, Jonas, Rosenthal, Emil, Borkar, Nrupa, Löffler, Rebekka, Madsen, Karsten K, Bräuner-Osborne, Hans, Schousboe, Arne, Ecker, Gerhard F, Wellendorph, Petrine, Clausen, Rasmus P
Published in Journal of medicinal chemistry (09.11.2017)
Published in Journal of medicinal chemistry (09.11.2017)
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Molecular Determinants underlying Delta Selective Compound 2 (DS2) Activity at δ -Containing GABA A Receptors
Falk-Petersen, Christina B, Rostrup, Frederik, Löffler, Rebekka, Buchleihtner, Stine, Harpsøe, Kasper, Gloriam, David E, Frølund, Bente, Wellendorph, Petrine
Published in Molecular pharmacology (01.07.2021)
Published in Molecular pharmacology (01.07.2021)
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Five-Membered N‑Heterocyclic Scaffolds as Novel Amino Bioisosteres at γ‑Aminobutyric Acid (GABA) Type A Receptors and GABA Transporters
Giraudo, Alessandro, Krall, Jacob, Bavo, Francesco, Nielsen, Birgitte, Kongstad, Kenneth T, Rolando, Barbara, De Blasio, Rossella, Gloriam, David E, Löffler, Rebekka, Thiesen, Louise, Harpsøe, Kasper, Frydenvang, Karla, Boschi, Donatella, Wellendorph, Petrine, Lolli, Marco L, Jensen, Anders A, Frølund, Bente
Published in Journal of medicinal chemistry (27.06.2019)
Published in Journal of medicinal chemistry (27.06.2019)
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Exploring the molecular determinants for subtype-selectivity of 2-amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid analogs as betaine/GABA transporter 1 (BGT1) substrate-inhibitors
Kickinger, Stefanie, Al-Khawaja, Anas, Haugaard, Anne Stæhr, Lie, Maria E. K., Bavo, Francesco, Löffler, Rebekka, Damgaard, Maria, Ecker, Gerhard F., Frølund, Bente, Wellendorph, Petrine
Published in Scientific reports (03.08.2020)
Published in Scientific reports (03.08.2020)
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Pharmacological Characterization of [3H]ATPCA as a Substrate for Studying the Functional Role of the Betaine/GABA Transporter 1 and the Creatine Transporter
Al-Khawaja, Anas, Haugaard, Anne S, Marek, Ales, Löffler, Rebekka, Thiesen, Louise, Santiveri, Mònica, Damgaard, Maria, Bundgaard, Christoffer, Frølund, Bente, Wellendorph, Petrine
Published in ACS chemical neuroscience (21.03.2018)
Published in ACS chemical neuroscience (21.03.2018)
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Unraveling the Molecular Determinants for GABA Transporter Subtype Selectivity
Kickinger, Stefanie, Al-Khawaja, Anas, Haugaard, Anne S., Lie, Maria E.K., Bavo, Francesco, Löffler, Rebekka, Damgaard, Maria, Frølund, Bente, Franz Ecker, Gerhard, Wellendorph, Petrine
Published in Biophysical journal (07.02.2020)
Published in Biophysical journal (07.02.2020)
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Structure-Activity Studies of 3,9-Diazaspiro[5.5]undecane-Based γ-Aminobutyric Acid Type A Receptor Antagonists with Immunomodulatory Effect
Bavo, Francesco, De-Jong, Heleen, Petersen, Jonas, Falk-Petersen, Christina Birkedahl, Loeffler, Rebekka, Sparrow, Emma, Rostrup, Frederik, Eliasen, Jannik Nicklas, Wilhelmsen, Kristine S., Barslund, Kasper, Bundgaard, Christoffer, Nielsen, Birgitte, Kristiansen, Uffe, Wellendorph, Petrine, Bogdanov, Yury, Frolund, Bente
Published in Journal of medicinal chemistry (23.12.2021)
Published in Journal of medicinal chemistry (23.12.2021)
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