Epigenomics and transcriptomics of systemic sclerosis CD4+ T cells reveal long-range dysregulation of key inflammatory pathways mediated by disease-associated susceptibility loci
Li, Tianlu, Ortiz-Fernández, Lourdes, Andrés-León, Eduardo, Ciudad, Laura, Javierre, Biola M., López-Isac, Elena, Guillén-Del-Castillo, Alfredo, Simeón-Aznar, Carmen Pilar, Ballestar, Esteban, Martin, Javier
Published in Genome medicine (25.09.2020)
Published in Genome medicine (25.09.2020)
Get full text
Journal Article
Analysis of ATP8B4 F436L Missense Variant in a Large Systemic Sclerosis Cohort
López‐Isac, Elena, Bossini‐Castillo, Lara, Palma, Ana B., Assassi, Shervin, Mayes, Maureen D., Simeón, Carmen P., Ortego‐Centeno, Norberto, Vicente, Esther, Tolosa, Carlos, Rubio‐Rivas, Manuel, Román‐Ivorra, José A., Beretta, Lorenzo, Moroncini, Gianluca, Hunzelmann, Nicolas, Distler, Jörg H. W., Riemekasten, Gabriella, de Vries‐Bouwstra, Jeska, Voskuyl, Alexandre E., Radstake, Timothy R. D. J., Herrick, Ariane, Denton, Christopher P., Fonseca, Carmen, Martín, Javier
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.06.2017)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.06.2017)
Get full text
Journal Article
Cross-disorder analysis of schizophrenia and 19 immune-mediated diseases identifies shared genetic risk
Pouget, Jennie G, Han, Buhm, Wu, Yang, Mignot, Emmanuel, Ollila, Hanna M, Barker, Jonathan, Spain, Sarah, Dand, Nick, Trembath, Richard, Martin, Javier, Mayes, Maureen D, Bossini-Castillo, Lara, López-Isac, Elena, Jin, Ying, Santorico, Stephanie A, Spritz, Richard A, Hakonarson, Hakon, Polychronakos, Constantin, Raychaudhuri, Soumya, Knight, Jo
Published in Human molecular genetics (15.10.2019)
Published in Human molecular genetics (15.10.2019)
Get full text
Journal Article
Combined genetic analysis of juvenile idiopathic arthritis clinical subtypes identifies novel risk loci, target genes and key regulatory mechanisms
López-Isac, Elena, Smith, Samantha L, Marion, Miranda C, Wood, Abigail, Sudman, Marc, Yarwood, Annie, Shi, Chenfu, Gaddi, Vasanthi Priyadarshini, Martin, Paul, Prahalad, Sampath, Eyre, Stephen, Orozco, Gisela, Morris, Andrew P, Langefeld, Carl D, Thompson, Susan D, Thomson, Wendy, Bowes, John
Published in Annals of the rheumatic diseases (01.03.2021)
Published in Annals of the rheumatic diseases (01.03.2021)
Get full text
Journal Article
The relationship between BDNF and physical activity on depression
Zarza-Rebollo, Juan Antonio, López-Isac, Elena, Rivera, Margarita, Gómez-Hernández, Laura, Pérez-Gutiérrez, Ana M., Molina, Esther
Published in Progress in neuro-psychopharmacology & biological psychiatry (30.08.2024)
Published in Progress in neuro-psychopharmacology & biological psychiatry (30.08.2024)
Get full text
Journal Article
Mutational landscape of risk variants in comorbid depression and obesity: a next-generation sequencing approach
Pérez-Gutiérrez, Ana M., Carmona, Rosario, Loucera, Carlos, Cervilla, Jorge A., Gutiérrez, Blanca, Molina, Esther, Lopez-Lopez, Daniel, Pérez-Florido, Javier, Zarza-Rebollo, Juan Antonio, López-Isac, Elena, Dopazo, Joaquín, Martínez-González, Luis Javier, Rivera, Margarita
Published in Molecular psychiatry (01.11.2024)
Published in Molecular psychiatry (01.11.2024)
Get full text
Journal Article
Interaction Effect between Physical Activity and the BDNF Val66Met Polymorphism on Depression in Women from the PISMA-ep Study
Zarza-Rebollo, Juan Antonio, Molina, Esther, López-Isac, Elena, Pérez-Gutiérrez, Ana M, Gutiérrez, Blanca, Cervilla, Jorge A, Rivera, Margarita
Published in International journal of environmental research and public health (12.02.2022)
Published in International journal of environmental research and public health (12.02.2022)
Get full text
Journal Article
No evidence that genetic predictors of susceptibility predict changes in core outcomes in JIA
Yarwood, Annie, Shoop-Worrall, Stephanie, López-Isac, Elena, Smith, Samantha Louise, Morris, Andrew P, Bowes, John David, Tordoff, Melissa, Hyrich, Kimme L., Thomson, Wendy, Eyre, Stephen
Published in Rheumatology (Oxford, England) (06.10.2022)
Published in Rheumatology (Oxford, England) (06.10.2022)
Get full text
Journal Article
Association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis–related calcinosis
Duffus, Kate, López-Isac, Elena, Teruel, Maria, Simeón, Carmen Pilar, Carreria, Patricia, Ortego-Centeno, Norberto, Vicente, Esther, Worthington, Jane, Herrick, Ariane L, Martin, Javier
Published in Rheumatology (Oxford, England) (01.07.2019)
Published in Rheumatology (Oxford, England) (01.07.2019)
Get full text
Journal Article
Genetics of systemic sclerosis
Bossini-Castillo, Lara, López-Isac, Elena, Mayes, Maureen D., Martín, Javier
Published in Seminars in immunopathology (01.09.2015)
Published in Seminars in immunopathology (01.09.2015)
Get full text
Journal Article
Book Review
Expression Quantitative Trait Locus Analysis in Systemic Sclerosis Identifies New Candidate Genes Associated With Multiple Aspects of Disease Pathology
Kerick, Martin, González‐Serna, David, Carnero‐Montoro, Elena, Teruel, Maria, Acosta‐Herrera, Marialbert, Makowska, Zuzanna, Buttgereit, Anne, Babaei, Sepideh, Barturen, Guillermo, López‐Isac, Elena, Lesche, Ralf, Beretta, Lorenzo, Alarcon‐Riquelme, Marta E., Martin, Javier, Vigone, Barbara, Pers, Jacques‐Olivier, Saraux, Alain, Devauchelle‐Pensec, Valérie, Cornec, Divi, Jousse‐Joulin, Sandrine, Lauwerys, Bernard, Ducreux, Julie, Maudoux, Anne‐Lise, Vasconcelos, Carlos, Tavares, Ana, Neves, Esmeralda, Faria, Raquel, Brandão, Mariana, Campar, Ana, Marinho, António, Farinha, Fátima, Almeida, Isabel, Mantecón, Miguel Angel Gonzalez‐Gay, Alonso, Ricardo Blanco, Martínez, Alfonso Corrales, Cervera, Ricard, Rodríguez‐Pintó, Ignasi, Espinosa, Gerard, Lories, Rik, De Langhe, Ellen, Hunzelmann, Nicolas, Belz, Doreen, Witte, Torsten, Baerlecken, Niklas, Stummvoll, Georg, Zauner, Michael, Lehner, Michaela, Collantes, Eduardo, Ortega‐Castro, Rafaela, Aguirre‐Zamorano, Mª Angeles, Escudero‐Contreras, Alejandro, Castro‐Villegas, Mª Carmen, Ortego, Norberto, Roldán, María Concepción Fernández, Raya, Enrique, Moleón, Inmaculada Jiménez, de Ramon, Enrique, Quintero, Isabel Díaz, Meroni, Pier Luigi, Gerosa, Maria, Schioppo, Tommaso, Artusi, Carolina, Chizzolini, Carlo, Zuber, Aleksandra, Wynar, Donatienne, Kovács, Laszló, Balog, Attila, Deák, Magdolna, Bocskai, Márta, Dulic, Sonja, Kádár, Gabriella, Hiepe, Falk, Gerl, Velia, Thiel, Silvia, Maresca, Manuel Rodriguez, López‐Berrio, Antonio, Aguilar‐Quesada, Rocío, Navarro‐Linares, Héctor
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2021)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2021)
Get full text
Journal Article
Analysis of the genetic component of systemic sclerosis in Iranian and Turkish populations through a genome-wide association study
González-Serna, David, López-Isac, Elena, Yilmaz, Neslihan, Gharibdoost, Farhad, Jamshidi, Ahmadreza, Kavosi, Hoda, Poursani, Shiva, Farsad, Faraneh, Direskeneli, Haner, Saruhan-Direskeneli, Guhrer, Vargas, Sofia, Sawalha, Amr H, Brown, Matthew A, Yavuz, Sule, Mahmoudi, Mahdi, Martin, Javier
Published in Rheumatology (Oxford, England) (01.02.2019)
Published in Rheumatology (Oxford, England) (01.02.2019)
Get full text
Journal Article
MAPPING THE SHARED FUNCTIONAL PROFILE BETWEEN DEPRESSION AND OBESITY BY PATHWAY SPECIFIC POLYGENIC RISK ANALYSIS
Gutiérrez, Ana M Pérez, Yao, Shuyang, López-Isac, Elena, Gutiérrez, Blanca, Cervilla, Jorge, Molina, Esther, Rivera, Margarita, Sullivan, Patrick
Published in IBRO neuroscience reports (01.10.2023)
Published in IBRO neuroscience reports (01.10.2023)
Get full text
Journal Article
Identification of IL12RB1 as a Novel Systemic Sclerosis Susceptibility Locus
López‐Isac, Elena, Bossini‐Castillo, Lara, Guerra, Sandra G., Denton, Christopher, Fonseca, Carmen, Assassi, Shervin, Zhou, Xiaodong, Mayes, Maureen D., Simeón, Carmen Pilar, Ortego‐Centeno, Norberto, Castellví, Iván, Carreira, Patricia, Gorlova, Olga, Beretta, Lorenzo, Santaniello, Alessandro, Lunardi, Claudio, Hesselstrand, Roger, Nordin, Annika, Riemekasten, Gabriela, Witte, Torsten, Hunzelmann, Nicolas, Kreuter, Alexander, Distler, Jörg H. W., Voskuyl, Alexandre E., Vries‐Bouwstra, Jeska, Koeleman, Bobby P., Herrick, Ariane, Worthington, Jane, Radstake, Timothy R. D. J., Martin, Javier
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.12.2014)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.12.2014)
Get full text
Journal Article
Comprehensive analysis of the major histocompatibility complex in systemic sclerosis identifies differential HLA associations by clinical and serological subtypes
Acosta-Herrera, Marialbert, Kerick, Martin, Lopéz-Isac, Elena, Assassi, Shervin, Beretta, Lorenzo, Simeón-Aznar, Carmen Pilar, Ortego-Centeno, Norberto, Proudman, Susanna M, Hunzelmann, Nicolas, Moroncini, Gianluca, de Vries-Bouwstra, Jeska K, Orozco, Gisela, Barton, Anne, Herrick, Ariane L, Terao, Chikashi, Allanore, Yannick, Brown, Matthew A, Radstake, Timothy RDJ, Fonseca, Carmen, Denton, Christopher P, Mayes, Maureen D, Martin, Javier, Carreira, P, Castellvi, I, Ríos, R, Callejas, J L, García Portales, R, Fernández-Nebro, A, García-Hernández, F J, Aguirre, M A, Fernández-Gutiérrez, B, Rodríguez-Rodríguez, L, García de la Peña, P, Vicente, E, Andreu, J L, Fernández de Castro, M, López-Longo, F J, Fonollosa, V, Guillén, A, Espinosa, G, Tolosa, C, Pros, A, Beltrán, E, Rodríguez Carballeira, M, Narváez, F J, Rubio Rivas, M, Ortiz-Santamaría, V, Madroñero, A B, González-Gay, M A, Díaz, B, Trapiella, L, Egurbide, M V, Fanlo-Mateo, P, Saez-Comet, L, Díaz, F, Roman-Ivorra, J A, Alegre Sancho, J J, Freire, M, Blanco Garcia, F J, Oreiro, N, Witte, T, Kreuter, A, Riemekasten, G, Airo, P, Magro, C, Voskuyl, A E, Vonk, M C, Hesselstrand, R, Nordin, A, Lunardi, C, Gabrielli, A, Hoffmann-Vold, A, Distler, J H W, Padyukov, L, Koeleman, B, Stevens, W, Nikpour, M, Zochling, J, Sahhar, J, Roddy, J, Nash, P, Tymms, K, Rischmueller, M, Lester, S
Published in Annals of the rheumatic diseases (01.08.2021)
Published in Annals of the rheumatic diseases (01.08.2021)
Get full text
Journal Article
Genomic Risk Score impact on susceptibility to systemic sclerosis
Bossini-Castillo, Lara, Villanueva-Martin, Gonzalo, Kerick, Martin, Acosta-Herrera, Marialbert, López-Isac, Elena, Simeón, Carmen P, Ortego-Centeno, Norberto, Assassi, Shervin, Hunzelmann, Nicolas, Gabrielli, Armando, de Vries-Bouwstra, J K, Allanore, Yannick, Fonseca, Carmen, Denton, Christopher P, Radstake, Timothy RDJ, Alarcón-Riquelme, Marta Eugenia, Beretta, Lorenzo, Mayes, Maureen D, Martin, Javier, Zochling, J., Sahhar, J., Roddy, J., Nash, P., Tymms, K., Rischmueller, M., Lester, S., Belz, Doreen, Ingegnoli, Francesca, Gómez, Yolanda Jimenez, Pedrera, Chary Lopez, Lories, Rik, Collantes-Estevez, Eduardo, Montanelli, Gaia, Piantoni, Silvia, Pinto, Ignasi Rodriguez, Vasconcelos, Carlos, Jamin, Christophe, Marañón, Concepción, Lann, Lucas Le, Simon, Quentin, Rouvière, Bénédicte, Varela, Nieves, Muchmore, Brian, Dufour, Aleksandra, Alvarez, Montserrat, Cremer, Jonathan, Barbarroja, Nuria, Gerl, Velia, Khodadadi, Laleh, Cheng, Qingyu, Buttgereit, Anne, Groof, Aurélie De, Ducreux, Julie, Trombetta, Elena, Li, Tianlu, Alvarez-Errico, Damiana, Witte, Torsten, Kniesch, Katja, Azevedo, Nancy, Neves, Esmeralda, Rao, Sambasiva, Jouve, Pierre-Emmanuel
Published in Annals of the rheumatic diseases (01.01.2021)
Published in Annals of the rheumatic diseases (01.01.2021)
Get full text
Journal Article
Influence of TYK2 in systemic sclerosis susceptibility: a new locus in the IL-12 pathway
López-Isac, Elena, Campillo-Davo, Diana, Bossini-Castillo, Lara, Guerra, Sandra G, Assassi, Shervin, Simeón, Carmen Pilar, Carreira, Patricia, Ortego-Centeno, Norberto, García de la Peña, Paloma, Beretta, Lorenzo, Santaniello, Alessandro, Bellocchi, Chiara, Lunardi, Claudio, Moroncini, Gianluca, Gabrielli, Armando, Riemekasten, Gabriela, Witte, Torsten, Hunzelmann, Nicolas, Kreuter, Alexander, Distler, Jörg HW, Voskuyl, Alexandre E, de Vries-Bouwstra, Jeska, Herrick, Ariane, Worthington, Jane, Denton, Christopher P, Fonseca, Carmen, Radstake, Timothy RDJ, Mayes, Maureen D, Martín, Javier
Published in Annals of the rheumatic diseases (01.08.2016)
Published in Annals of the rheumatic diseases (01.08.2016)
Get full text
Journal Article
An MIF Promoter Polymorphism Is Associated with Susceptibility to Pulmonary Arterial Hypertension in Diffuse Cutaneous Systemic Sclerosis
Bossini-Castillo, Lara, Campillo-Davó, Diana, López-Isac, Elena, Carmona, Francisco David, Simeon, Carmen P, Carreira, Patricia, Callejas-Rubio, José Luis, Castellví, Iván, Fernández-Nebro, Antonio, Rodríguez-Rodríguez, Luis, Rubio-Rivas, Manel, García-Hernández, Francisco J, Madroñero, Ana Belén, Beretta, Lorenzo, Santaniello, Alessandro, Lunardi, Claudio, Airó, Paolo, Hoffmann-Vold, Anna-Maria, Kreuter, Alexander, Riemekasten, Gabriela, Witte, Torsten, Hunzelmann, Nicolas, Vonk, Madelon C, Voskuyl, Alexandre E, de Vries-Bouwstra, J, Shiels, Paul, Herrick, Ariane, Worthington, Jane, Radstake, Timothy R D J, Martin, Javier
Published in Journal of rheumatology (01.10.2017)
Published in Journal of rheumatology (01.10.2017)
Get more information
Journal Article