A first‐in‐human oral dose study of mesdopetam (IRL790) to assess its safety, tolerability, and pharmacokinetics in healthy male volunteers
Sjöberg, Folke, Waters, Susanna, Löfberg, Boel, Sonesson, Clas, Waters, Nicholas, Tedroff, Joakim
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Published in Pharmacology research & perspectives (01.05.2021)
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Isoindolinone compounds active as Kv1.5 blockers identified using a multicomponent reaction approach
Kajanus, Johan, Jacobson, Ingemar, Åstrand, Annika, Olsson, Roine I., Gran, Ulrik, Björe, Annika, Fjellström, Ola, Davidsson, Öjvind, Emtenäs, Hans, Dahlén, Anders, Löfberg, Boel, Yuan, Zhong-Qing, Sundell, Johan, Cassel, Johan, Gyll, Jonna, Iliefski, Tommy, Högberg, Ågot, Lindhardt, Emma, Malmberg, Jesper
Published in Bioorganic & medicinal chemistry letters (15.04.2016)
Published in Bioorganic & medicinal chemistry letters (15.04.2016)
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Synthesis and evaluation of diphenylphosphinic amides and diphenylphosphine oxides as inhibitors of Kv1.5
Olsson, Roine I., Jacobson, Ingemar, Boström, Jonas, Fex, Tomas, Björe, Annika, Olsson, Christina, Sundell, Johan, Gran, Ulrik, Öhrn, Anna, Nordin, Andreas, Gyll, Jonna, Thorstensson, Maria, Hayen, Ahlke, Aplander, Karolina, Hidestål, Olle, Jiang, Fanyi, Linhardt, Gunilla, Forsström, Elin, Collins, Teresa, Sundqvist, Monika, Lindhardt, Emma, Åstrand, Annika, Löfberg, Boel
Published in Bioorganic & medicinal chemistry letters (01.02.2013)
Published in Bioorganic & medicinal chemistry letters (01.02.2013)
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In Silico Predictions and In Vivo Results of Drug-Drug Interactions by Ketoconazole and Verapamil on AZD1305, a Combined Ion Channel Blocker and a Sensitive CYP3A4 Substrate
Johansson, Susanne, Löfberg, Boel, Aunes, Maria, Lunde, Helen, Frison, Lars, Edvardsson, Nils, Cullberg, Marie
Published in Clinical pharmacology in drug development (01.09.2016)
Published in Clinical pharmacology in drug development (01.09.2016)
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Impact of input parameters on the prediction of hepatic plasma clearance using the well-stirred model
Wan, Hong, Bold, Peter, Larsson, Lars-Olof, Ulander, Johan, Peters, Sheila, Löfberg, Boel, Ungell, Anna-Lena, Någård, Mats, Llinàs, Antonio
Published in Current drug metabolism (01.09.2010)
Published in Current drug metabolism (01.09.2010)
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Lactam sulfonamides as potent inhibitors of the Kv1.5 potassium ion channel
Olsson, Roine I., Jacobson, Ingemar, Iliefski, Tommy, Bostrom, Jonas, Davidsson, Ojvind, Fjellstrom, Ola, Bjore, Annika, Olsson, Christina, Sundell, Johan, Gran, Ulrik, Gyll, Jonna, Malmberg, Jesper, Hidestal, Olle, Emtenas, Hans, Svensson, Tor, Yuan, Zhong-Qing, Strandlund, Gert, Astrand, Annika, Lindhardt, Emma, Linhardt, Gunilla, Forsstrom, Elin, Hogberg, Agot, Persson, Frida, Andersson, Birgit, Ronnborg, Anna, Lofberg, Boel
Published in Bioorganic & medicinal chemistry letters (01.03.2014)
Published in Bioorganic & medicinal chemistry letters (01.03.2014)
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Phosphonate quinoxalinedione AMPA antagonists
TURSKI, Lechoslaw, SCHNEIDER, Herbert H, NEUHAUS, Roland, MCDONALD, Fiona, JONES, Graham H, LÖFBERG, Boel, SCHWEINFURTH, Hermann, HUTH, Andreas, KRÜGER, Martin, OTTOW, Eckhard
Published in Restorative neurology and neuroscience (2000)
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Published in Restorative neurology and neuroscience (2000)
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Teratogenicity of steady-state concentrations of etretinate and metabolite acitretin maintained in maternal plasma and embryo by intragastric infusion during organogenesis in the mouse: a possible model for the extended elimination phase in human therapy
Löfberg, B, Reiners, J, Spielmann, H, Nau, H
Published in Developmental pharmacology and therapeutics (1990)
Published in Developmental pharmacology and therapeutics (1990)
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Extrahepatic sites of metabolism of halothane in the rat
Ghantous, H, Löfberg, B, Tjälve, H, Danielsson, B R, Dencker, L
Published in Pharmacology & toxicology (01.03.1988)
Published in Pharmacology & toxicology (01.03.1988)
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