Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin
Ho, Gwo Yaw, Kyran, Elizabeth L, Bedo, Justin, Wakefield, Matthew J, Ennis, Darren P, Mirza, Hasan B, Vandenberg, Cassandra J, Lieschke, Elizabeth, Farrell, Andrew, Hadla, Anthony, Lim, Ratana, Dall, Genevieve, Vince, James E, Chua, Ngee Kiat, Kondrashova, Olga, Upstill-Goddard, Rosanna, Bailey, Ulla-Maja, Dowson, Suzanne, Roxburgh, Patricia, Glasspool, Rosalind M, Bryson, Gareth, Biankin, Andrew V, Cooke, Susanna L, Ratnayake, Gayanie, McNally, Orla, Traficante, Nadia, DeFazio, Anna, Weroha, S John, Bowtell, David D, McNeish, Iain A, Papenfuss, Anthony T, Scott, Clare L, Barker, Holly E
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Published in Cancer research (Chicago, Ill.) (02.12.2022)
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Multiple pathological mechanisms contribute to hippocampal damage in the experimental autoimmune encephalomyelitis model of multiple sclerosis
Kyran, Elizabeth L, Robinson, Christine, Kocovski, Pece, Li, Zhenjiang, Dang, Phuc T, Hale, Matthew W, Orian, Jacqueline M
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BRCA1 secondary splice-site mutations drive exon-skipping and PARP inhibitor resistance
Nesic, Ksenija, Krais, John J, Wang, Yifan, Vandenberg, Cassandra J, Patel, Pooja, Cai, Kathy Q, Kwan, Tanya, Lieschke, Elizabeth, Ho, Gwo-Yaw, Barker, Holly E, Bedo, Justin, Casadei, Silvia, Farrell, Andrew, Radke, Marc, Shield-Artin, Kristy, Penington, Jocelyn S, Geissler, Franziska, Kyran, Elizabeth, Betsch, Robert, Xu, Lijun, Zhang, Fan, Dobrovic, Alexander, Olesen, Inger, Kristeleit, Rebecca, Oza, Amit, McNeish, Iain, Ratnayake, Gayanie, Traficante, Nadia, DeFazio, Anna, Bowtell, David D L, Harding, Thomas C, Lin, Kevin, Swisher, Elizabeth M, Kondrashova, Olga, Scott, Clare L, Johnson, Neil, Wakefield, Matthew J
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Published in Molecular cancer (05.08.2024)
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Targeting homologous recombination deficiency in uterine leiomyosarcoma
Dall, Genevieve, Vandenberg, Cassandra J, Nesic, Ksenija, Ratnayake, Gayanie, Zhu, Wenying, Vissers, Joseph H A, Bedő, Justin, Penington, Jocelyn, Wakefield, Matthew J, Kee, Damien, Carmagnac, Amandine, Lim, Ratana, Shield-Artin, Kristy, Milesi, Briony, Lobley, Amanda, Kyran, Elizabeth L, O'Grady, Emily, Tram, Joshua, Zhou, Warren, Nugawela, Devindee, Stewart, Kym Pham, Caldwell, Reece, Papadopoulos, Lia, Ng, Ashley P, Dobrovic, Alexander, Fox, Stephen B, McNally, Orla, Power, Jeremy D, Meniawy, Tarek, Tan, Teng Han, Collins, Ian M, Klein, Oliver, Barnett, Stephen, Olesen, Inger, Hamilton, Anne, Hofmann, Oliver, Grimmond, Sean, Papenfuss, Anthony T, Scott, Clare L, Barker, Holly E
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The microtubule inhibitor eribulin demonstrates efficacy in platinum-resistant and refractory high-grade serous ovarian cancer patient-derived xenograft models
Ho, Gwo Yaw, Vandenberg, Cassandra J., Lim, Ratana, Christie, Elizabeth L., Garsed, Dale W., Lieschke, Elizabeth, Nesic, Ksenija, Kondrashova, Olga, Ratnayake, Gayanie, Radke, Marc, Penington, Jocelyn S., Carmagnac, Amandine, Heong, Valerie, Kyran, Elizabeth L., Zhang, Fan, Traficante, Nadia, Huang, Ruby, Dobrovic, Alexander, Swisher, Elizabeth M., McNally, Orla, Kee, Damien, Wakefield, Matthew J., Papenfuss, Anthony T., Bowtell, David D. L., Barker, Holly E., Scott, Clare L.
Published in Therapeutic advances in medical oncology (01.01.2023)
Published in Therapeutic advances in medical oncology (01.01.2023)
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Journal Article
BRCA1 secondary splice-site mutations drive exon-skipping and PARP inhibitor resistance
Nesic, Ksenija, Krais, John J, Vandenberg, Cassandra J, Wang, Yifan, Patel, Pooja, Cai, Kathy Q, Kwan, Tanya, Lieschke, Elizabeth, Ho, Gwo-Yaw, Barker, Holly E, Bedo, Justin, Casadei, Silvia, Farrell, Andrew, Radke, Marc, Shield-Artin, Kristy, Penington, Jocelyn S, Geissler, Franziska, Kyran, Elizabeth, Zhang, Fan, Dobrovic, Alexander, Olesen, Inger, Kristeleit, Rebecca, Oza, Amit, Ratnayake, Gayanie, Traficante, Nadia, DeFazio, Anna, Bowtell, David D L, Harding, Thomas C, Lin, Kevin, Swisher, Elizabeth M, Kondrashova, Olga, Scott, Clare L, Johnson, Neil, Wakefield, Matthew J
Published in medRxiv : the preprint server for health sciences (28.08.2023)
Published in medRxiv : the preprint server for health sciences (28.08.2023)
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Hedgehog inhibition impaired platinum response in high-grade serous ovarian cancer harboring high hedgehog ligand expression and mTOR pathway activation
Ho, Gwo Yaw, Lieschke, Elizabeth, Kyran, Elizabeth, Shield-Artin, Kristy, Kondrashova, Olga, Barker, Holly, Hollian, Robert, Cazet, Aurelie, Phuong, Thuan, Swarbrick, Alex, McNally, Orla, Bowtell, David, Wakefield, Matthew, Scott, Clare L.
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
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Ovarian carcinosarcoma genomics and pre-clinical models highlight the N-MYC pathway as a key driver and susceptibility to EMT-targeting therapy
Gwo, Yaw Ho, Kyran, Elizabeth L, Bedo, Justin, Wakefield, Matthew J, Ennis, Darren P, Mirza, Hasan B, Lieschke, Elizabeth, Vandenberg, Cassandra J, Kondrashova, Olga, Upstill-Goddard, Rosie, Bailey, Ulla-Maja, Dowson, Suzanne, Roxburgh, Patricia, Glasspool, Rosalind M, Bryson, Gareth, Biankin, Andrew V, Cooke, Susanna L, Ratnayake, Gayanie, Mcnally, Orla, Traficante, Nadia, Australian Ovarian Cancer Study, Defazio, Anna, Weroha, John, Bowtell, David D, Mcneish, Iain A, Papenfuss, Anthony T, Scott, Clare L, Barker, Holly E
Published in bioRxiv (24.11.2020)
Published in bioRxiv (24.11.2020)
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