Defective Mitochondrial Dynamics and Protein Degradation Pathways Underlie Cadmium-Induced Neurotoxicity and Cell Death in Huntington's Disease Striatal Cells
Kamitsuka, Paul J, Ghanem, Marwan M, Ziar, Rania, McDonald, Sarah E, Thomas, Morgan G, Kwakye, Gunnar F
Published in International journal of molecular sciences (13.04.2023)
Published in International journal of molecular sciences (13.04.2023)
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A gold-based inhibitor of oxidative phosphorylation is effective against triple negative breast cancer
Mertens, R. Tyler, Kim, Jong Hyun, Ofori, Samuel, Olelewe, Chibuzor, Kamitsuka, Paul J., Kwakye, Gunnar F., Awuah, Samuel G.
Published in Biomedicine & pharmacotherapy (01.01.2024)
Published in Biomedicine & pharmacotherapy (01.01.2024)
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Synthetic Control of Mitochondrial Dynamics: Developing Three-Coordinate Au(I) Probes for Perturbation of Mitochondria Structure and Function
Mertens, R. Tyler, Jennings, William C., Ofori, Samuel, Kim, Jong Hyun, Parkin, Sean, Kwakye, Gunnar F., Awuah, Samuel G.
Published in JACS Au (26.04.2021)
Published in JACS Au (26.04.2021)
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Role of manganese in neurodegenerative diseases
Bowman, Aaron B., Kwakye, Gunnar F., Herrero Hernández, Elena, Aschner, Michael
Published in Journal of trace elements in medicine and biology (01.12.2011)
Published in Journal of trace elements in medicine and biology (01.12.2011)
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Manganese-Induced Parkinsonism and Parkinson's Disease: Shared and Distinguishable Features
Kwakye, Gunnar F, Paoliello, Monica M B, Mukhopadhyay, Somshuvra, Bowman, Aaron B, Aschner, Michael
Published in International journal of environmental research and public health (06.07.2015)
Published in International journal of environmental research and public health (06.07.2015)
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Atropa belladonna neurotoxicity: Implications to neurological disorders
Kwakye, Gunnar F., Jiménez, Jennifer, Jiménez, Jessica A., Aschner, Michael
Published in Food and chemical toxicology (01.06.2018)
Published in Food and chemical toxicology (01.06.2018)
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Disease-Toxicant Interactions in Parkinson’s Disease Neuropathology
Kwakye, Gunnar F., McMinimy, Rachael A., Aschner, Michael
Published in Neurochemical research (01.06.2017)
Published in Neurochemical research (01.06.2017)
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Acute exposure to chlorpyrifos caused NADPH oxidase mediated oxidative stress and neurotoxicity in a striatal cell model of Huntington’s disease
Dominah, Gifty A., McMinimy, Rachael A., Kallon, Sallay, Kwakye, Gunnar F.
Published in Neurotoxicology (Park Forest South) (01.05.2017)
Published in Neurotoxicology (Park Forest South) (01.05.2017)
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Heterozygous huntingtin promotes cadmium neurotoxicity and neurodegeneration in striatal cells via altered metal transport and protein kinase C delta dependent oxidative stress and apoptosis signaling mechanisms
Kwakye, Gunnar F., Jiménez, Jessica A., Thomas, Morgan G., Kingsley, Brett A., McIIvin, Matthew, Saito, Mak A., Korley, Edmund M.
Published in Neurotoxicology (Park Forest South) (01.01.2019)
Published in Neurotoxicology (Park Forest South) (01.01.2019)
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α-Synuclein Enhances Cadmium Uptake and Neurotoxicity via Oxidative Stress and Caspase Activated Cell Death Mechanisms in a Dopaminergic Cell Model of Parkinson’s Disease
Chong, Weelic, Jiménez, Jessica, McIIvin, Matthew, Saito, Mak A., Kwakye, Gunnar F.
Published in Neurotoxicity research (01.08.2017)
Published in Neurotoxicity research (01.08.2017)
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Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse model
Bichell, Terry Jo V., Wegrzynowicz, Michal, Tipps, K. Grace, Bradley, Emma M., Uhouse, Michael A., Bryan, Miles, Horning, Kyle, Fisher, Nicole, Dudek, Karrie, Halbesma, Timothy, Umashanker, Preethi, Stubbs, Andrew D., Holt, Hunter K., Kwakye, Gunnar F., Tidball, Andrew M., Colbran, Roger J., Aschner, Michael, Neely, M. Diana, Di Pardo, Alba, Maglione, Vittorio, Osmand, Alexander, Bowman, Aaron B.
Published in Biochimica et biophysica acta (01.06.2017)
Published in Biochimica et biophysica acta (01.06.2017)
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Novel high-throughput assay to assess cellular manganese levels in a striatal cell line model of Huntington's disease confirms a deficit in manganese accumulation
Kwakye, Gunnar F., Li, Daphne, Bowman, Aaron B.
Published in Neurotoxicology (Park Forest South) (01.10.2011)
Published in Neurotoxicology (Park Forest South) (01.10.2011)
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Disease-toxicant screen reveals a neuroprotective interaction between Huntington's disease and manganese exposure
Williams, B. Blairanne, Li, Daphne, Wegrzynowicz, Michal, Vadodaria, Bhavin K, Anderson, Joel G, Kwakye, Gunnar F, Aschner, Michael, Erikson, Keith M, Bowman, Aaron B
Published in Journal of neurochemistry (01.01.2010)
Published in Journal of neurochemistry (01.01.2010)
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Journal Article
Cellular fura-2 manganese extraction assay (CFMEA)
Kwakye, Gunnar F, Li, Daphne, Kabobel, Olympia A, Bowman, Aaron B
Published in Current protocols in toxicology (01.05.2011)
Published in Current protocols in toxicology (01.05.2011)
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Novel high-throughput assay to assess cellular manganese levels in a striatal cell line model of Huntington's disease confirms a deficit in manganese accumulation: Unifying Mechanisms of Neurological Disorders: Scientific, Translational, and Clinical Implications
KWAKYE, Gunnar F, LI, Daphne, BOWMAN, Aaron B
Published in Neurotoxicology (Park Forest South) (2011)
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Published in Neurotoxicology (Park Forest South) (2011)
Journal Article
Die Rolle von Mangan bei neurodegenerativen Erkrankungen
Bowman, Aaron B., Kwakye, Gunnar F., Hernández, Elena Herrero, Aschner, Michael
Published in Perspectives in medicine (01.03.2014)
Published in Perspectives in medicine (01.03.2014)
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