Oral activity of a nature-derived cyclic peptide for the treatment of multiple sclerosis
Thell, Kathrin, Hellinger, Roland, Sahin, Emine, Michenthaler, Paul, Gold-Binder, Markus, Haider, Thomas, Kuttke, Mario, Liutkevičiūtė, Zita, Göransson, Ulf, Gründemann, Carsten, Schabbauer, Gernot, Gruber, Christian W.
Published in Proceedings of the National Academy of Sciences - PNAS (12.04.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (12.04.2016)
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Journal Article
Macrophage PTEN regulates expression and secretion of arginase I modulating innate and adaptive immune responses
Sahin, Emine, Haubenwallner, Stefan, Kuttke, Mario, Kollmann, Isabella, Halfmann, Angela, Dohnal, Alexander M, Dohnal, Alexander B, Chen, Li, Cheng, Paul, Hoesel, Bastian, Einwallner, Elisa, Brunner, Julia, Kral, Julia B, Schrottmaier, Waltraud C, Thell, Kathrin, Saferding, Victoria, Blüml, Stephan, Schabbauer, Gernot
Published in The Journal of immunology (1950) (15.08.2014)
Published in The Journal of immunology (1950) (15.08.2014)
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Journal Article
Potential of unglycosylated horseradish peroxidase variants for enzyme prodrug cancer therapy
Humer, Diana, Furlanetto, Valentina, Schruef, Anna-Katharina, Wlodarczyk, Angelika, Kuttke, Mario, Divne, Christina, Spadiut, Oliver
Published in Biomedicine & pharmacotherapy (01.10.2021)
Published in Biomedicine & pharmacotherapy (01.10.2021)
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Journal Article
PI3K Signaling in Dendritic Cells Aggravates DSS-Induced Colitis
Kuttke, Mario, Hromadová, Dominika, Yildirim, Ceren, Brunner, Julia S, Vogel, Andrea, Paar, Hannah, Peters, Sophie, Weber, Maria, Hofmann, Melanie, Kerndl, Martina, Kieler, Markus, Datler, Hannes, Musiejovsky, Laszlo, Salzmann, Manuel, Lang, Michaela, Soukup, Klara, Halfmann, Angela, Sharif, Omar, Schabbauer, Gernot
Published in Frontiers in immunology (19.04.2022)
Published in Frontiers in immunology (19.04.2022)
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Journal Article
Loss of MAPK-activated protein kinase 2 enables potent dendritic cell-driven anti-tumour T cell response
Soukup, Klara, Halfmann, Angela, Dillinger, Barbara, Poyer, Fiona, Martin, Katharina, Blauensteiner, Bernadette, Kauer, Maximilian, Kuttke, Mario, Schabbauer, Gernot, Dohnal, Alexander M.
Published in Scientific reports (18.09.2017)
Published in Scientific reports (18.09.2017)
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Journal Article
Abstract 3055: Xentuzumab, a humanized IGF-1 and IGF-2 ligand co-neutralizing monoclonal antibody, shows efficacy in a human breast cancer model of bone metastasis
Weyer-Czernilofsky, Ulrike, Krecioch, Izabela, Handschuh, Stephan, Glösmann, Martin, Kuttke, Mario, Jacob, Robin, Obenauf, Anna C.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
JAK1 signaling in dendritic cells promotes peripheral tolerance in autoimmunity through PD-L1-mediated regulatory T cell induction
Vogel, Andrea, Martin, Katharina, Soukup, Klara, Halfmann, Angela, Kerndl, Martina, Brunner, Julia S., Hofmann, Melanie, Oberbichler, Laura, Korosec, Ana, Kuttke, Mario, Datler, Hannes, Kieler, Markus, Musiejovsky, Laszlo, Dohnal, Alexander, Sharif, Omar, Schabbauer, Gernot
Published in Cell reports (Cambridge) (22.02.2022)
Published in Cell reports (Cambridge) (22.02.2022)
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Journal Article
Acquired resistance to anti-MAPK targeted therapy confers an immune-evasive tumor microenvironment and cross-resistance to immunotherapy in melanoma
Haas, Lisa, Elewaut, Anais, Gerard, Camille L, Umkehrer, Christian, Leiendecker, Lukas, Pedersen, Malin, Krecioch, Izabela, Hoffmann, David, Novatchkova, Maria, Kuttke, Mario, Neumann, Tobias, da Silva, Ines Pires, Witthock, Harriet, Cuendet, Michel A, Carotta, Sebastian, Harrington, Kevin J, Zuber, Johannes, Scolyer, Richard A, Long, Georgina V, Wilmott, James S, Michielin, Olivier, Vanharanta, Sakari, Wiesner, Thomas, Obenauf, Anna C
Published in Nature cancer (01.07.2021)
Published in Nature cancer (01.07.2021)
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Journal Article
Sustained PI3K Activation exacerbates BLM-induced Lung Fibrosis via activation of pro-inflammatory and pro-fibrotic pathways
Kral, Julia Barbara, Kuttke, Mario, Schrottmaier, Waltraud Cornelia, Birnecker, Birgit, Warszawska, Joanna, Wernig, Christina, Paar, Hannah, Salzmann, Manuel, Sahin, Emine, Brunner, Julia Stefanie, Österreicher, Christoph, Knapp, Sylvia, Assinger, Alice, Schabbauer, Gernot
Published in Scientific reports (14.03.2016)
Published in Scientific reports (14.03.2016)
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Journal Article
Proteomic Profiling of Advanced Melanoma Patients to Predict Therapeutic Response to Anti-PD-1 Therapy
Zila, Nina, Eichhoff, Ossia M, Steiner, Irene, Mohr, Thomas, Bileck, Andrea, Cheng, Phil F, Leitner, Alexander, Gillet, Ludovic, Sajic, Tatjana, Goetze, Sandra, Friedrich, Betty, Bortel, Patricia, Strobl, Johanna, Reitermaier, René, Hogan, Sabrina A, Martínez Gómez, Julia M, Staeger, Ramon, Tuchmann, Felix, Peters, Sophie, Stary, Georg, Kuttke, Mario, Elbe-Bürger, Adelheid, Hoeller, Christoph, Kunstfeld, Rainer, Weninger, Wolfgang, Wollscheid, Bernd, Dummer, Reinhard, French, Lars E, Gerner, Christopher, Aebersold, Ruedi, Levesque, Mitchell P, Paulitschke, Verena
Published in Clinical cancer research (05.01.2024)
Published in Clinical cancer research (05.01.2024)
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Journal Article
Role of endothelial IkB kinase 2 in atherosclerosis
Mussbacher, Marion, Salzmann, Manuel, Kuttke, Mario, Basilio, Jose, Hösel, Bastian, Assinger, Alice, Schmid, Johannes
Published in Atherosclerosis (01.08.2017)
Published in Atherosclerosis (01.08.2017)
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Journal Article
Fab antibody fragment-functionalized liposomes for specific targeting of antigen-positive cells
Ohradanova-Repic, Anna, Nogueira, Eugénia, Hartl, Ingrid, Gomes, Andreia C., Preto, Ana, Steinhuber, Eva, Mühlgrabner, Vanessa, Repic, Marko, Kuttke, Mario, Zwirzitz, Alexander, Prouza, Marek, Suchanek, Miloslav, Wozniak-Knopp, Gordana, Horejsi, Vaclav, Schabbauer, Gernot, Cavaco-Paulo, Artur, Stockinger, Hannes
Published in Nanomedicine (01.01.2018)
Published in Nanomedicine (01.01.2018)
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Journal Article
Macrophage Phosphoproteome Analysis Reveals MINCLE-dependent and -independent Mycobacterial Cord Factor Signaling[S]
Hansen, Madlen, Peltier, Julian, Killy, Barbara, Amin, Bushra, Bodendorfer, Barbara, Härtlova, Anetta, Uebel, Sebastian, Bosmann, Markus, Hofmann, Jörg, Büttner, Christian, Ekici, Arif B., Kuttke, Mario, Franzyk, Henrik, Foged, Camilla, Beer-Hammer, Sandra, Schabbauer, Gernot, Trost, Matthias, Lang, Roland
Published in Molecular & cellular proteomics (01.04.2019)
Published in Molecular & cellular proteomics (01.04.2019)
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Journal Article
TAT-MeCP2 protein variants rescue disease phenotypes in human and mouse models of Rett syndrome
Steinkellner, Hannes, Kempaiah, Prakasha, Beribisky, Alexander V., Pferschy, Sandra, Etzler, Julia, Huber, Anna, Sarne, Victoria, Neuhaus, Winfried, Kuttke, Mario, Bauer, Jan, Arunachalam, Jayamuruga P., Christodoulou, John, Dressel, Ralf, Mildner, Alexander, Prinz, Marco, Laccone, Franco
Published in International journal of biological macromolecules (01.06.2022)
Published in International journal of biological macromolecules (01.06.2022)
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Journal Article
Platelet p110β mediates platelet-leukocyte interaction and curtails bacterial dissemination in pneumococcal pneumonia
Schrottmaier, Waltraud Cornelia, Kral-Pointner, Julia Barbara, Salzmann, Manuel, Mussbacher, Marion, Schmuckenschlager, Anna, Pirabe, Anita, Brunnthaler, Laura, Kuttke, Mario, Maier, Barbara, Heber, Stefan, Datler, Hannes, Ekici, Yasemin, Niederreiter, Birgit, Heber, Ulrike, Blomgren, Bo, Gorki, Anna-Dorothea, Söderberg-Nauclér, Cecilia, Payrastre, Bernard, Gratacap, Marie-Pierre, Knapp, Sylvia, Schabbauer, Gernot, Assinger, Alice
Published in Cell reports (Cambridge) (08.11.2022)
Published in Cell reports (Cambridge) (08.11.2022)
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Journal Article
Ikk2-mediated inflammatory activation of arterial endothelial cells promotes the development and progression of atherosclerosis
Mussbacher, Marion, Salzmann, Manuel, Haigl, Barbara, Basílio, José, Hochreiter, Bernhard, Gleitsmann, Viola, Moser, Bernhard, Hoesel, Bastian, Suur, Bianca E., Puhm, Florian, Ungerböck, Caroline, Kuttke, Mario, Forteza, Maria J., Binder, Christoph J., Ketelhuth, Daniel F.J., Assinger, Alice, Schmid, Johannes A.
Published in Atherosclerosis (01.08.2020)
Published in Atherosclerosis (01.08.2020)
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Journal Article
Abstract 5936: A novel class of orally bioavailable small molecules induces potent and sustained tumor growth inhibition and T cell infiltration in various solid tumor mouse models
Gapp, Bianca, Zischinsky, Gunther, Urban, Maria, Birnbacher, Nora, Schwarzböck, Alice, Grünaug, Sabine, Gastaldi, Tommaso, Stütz, Anton, Nussbaumer, Peter, Stranner, Stefan, Buchberger, Julia, Birbach, Andreas, Schögl, Daniela, Kuttke, Mario, Dohnal, Alexander, Gugenberger, Romana
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Abstract A43: MAPK-activated protein kinase MK2 exerts immune regulatory functions in the microenvironment of orthotopic tumors
Soukup, Klara, Halfmann, Angela, Poyer, Fiona, Martin, Katharina, Blauensteiner, Bernadette, Huber, Bastien, Kuttke, Mario, Schabbauer, Gernot, Zopf, Lydia, Zinnanti, Jelena, Dohnal, Alexander Michael
Published in Cancer research (Chicago, Ill.) (01.08.2016)
Published in Cancer research (Chicago, Ill.) (01.08.2016)
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Journal Article
Food-derived peroxidized fatty acids may trigger hepatic inflammation: A novel hypothesis to explain steatohepatitis
Böhm, Therese, Berger, Heidi, Nejabat, Marzieh, Riegler, Teresa, Kellner, Florian, Kuttke, Mario, Sagmeister, Sandra, Bazanella, Monika, Stolze, Klaus, Daryabeigi, Anahita, Bintner, Nora, Murkovic, Michael, Wagner, Karl-Heinz, Schulte-Hermann, Rolf, Rohr-Udilova, Nataliya, Huber, Wolfgang, Grasl-Kraupp, Bettina
Published in Journal of hepatology (01.09.2013)
Published in Journal of hepatology (01.09.2013)
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Abstract LB187: Case report: APN401, a novel cancer therapy using Cbl-b silenced autologous PBMCs, induced stable disease in two patients with advanced solid tumors
Kuttke, Mario, Dohnal, Alexander, Tanzmann, Andreas, Pribitzer, Beate, Batrina, Felix, Bunka, Stefan, Spagl, Sophia, Branka, Manuela, Bischof, Sarah, Thell, Kathrin, Urban, Maria, Muehleisen, Hannes, Peball, Bernhard, Gapp, Bianca, Halfmann, Angela, Raderer, Markus, Prager, Gerald, Fuereder, Thorsten, Gugenberger, Romana, Worel, Nina
Published in Cancer research (Chicago, Ill.) (14.04.2023)
Published in Cancer research (Chicago, Ill.) (14.04.2023)
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