Deciphering the SAM- and metal-dependent mechanism of O-methyltransferases in cystargolide and belactosin biosynthesis: A structure–activity relationship study
Kuttenlochner, Wolfgang, Beller, Patrick, Kaysser, Leonard, Groll, Michael
Published in The Journal of biological chemistry (01.09.2024)
Published in The Journal of biological chemistry (01.09.2024)
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Journal Article
Optical Control of Proteasomal Protein Degradation with a Photoswitchable Lipopeptide
Morstein, Johannes, Amatuni, Alexander, Shuster, Anton, Kuttenlochner, Wolfgang, Ko, Tongil, Abegg, Daniel, Groll, Michael, Adibekian, Alexander, Renata, Hans, Trauner, Dirk H.
Published in Angewandte Chemie International Edition (19.02.2024)
Published in Angewandte Chemie International Edition (19.02.2024)
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Journal Article
Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria
Shi, Yi-Ming, Hirschmann, Merle, Shi, Yan-Ni, Ahmed, Shabbir, Abebew, Desalegne, Tobias, Nicholas J., Grün, Peter, Crames, Jan J., Pöschel, Laura, Kuttenlochner, Wolfgang, Richter, Christian, Herrmann, Jennifer, Müller, Rolf, Thanwisai, Aunchalee, Pidot, Sacha J., Stinear, Timothy P., Groll, Michael, Kim, Yonggyun, Bode, Helge B.
Published in Nature chemistry (01.06.2022)
Published in Nature chemistry (01.06.2022)
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Journal Article
Structural and Mechanistic Insights into C−S Bond Formation in Gliotoxin
Scherlach, Kirstin, Kuttenlochner, Wolfgang, Scharf, Daniel H., Brakhage, Axel A., Hertweck, Christian, Groll, Michael, Huber, Eva M.
Published in Angewandte Chemie International Edition (14.06.2021)
Published in Angewandte Chemie International Edition (14.06.2021)
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Journal Article
Characterization of the cystargolide biosynthetic gene cluster and functional analysis of the methyltransferase CysG
Beller, Patrick, Fink, Phillipp, Wolf, Felix, Männle, Daniel, Helmle, Irina, Kuttenlochner, Wolfgang, Unterfrauner, Daniel, Engelbrecht, Alicia, Staudt, Nicole D, Kulik, Andreas, Groll, Michael, Gross, Harald, Kaysser, Leonard
Published in The Journal of biological chemistry (01.01.2024)
Published in The Journal of biological chemistry (01.01.2024)
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Journal Article
Evolution-inspired engineering of nonribosomal peptide synthetases
Bozhüyük, Kenan A J, Präve, Leonard, Kegler, Carsten, Schenk, Leonie, Kaiser, Sebastian, Schelhas, Christian, Shi, Yan-Ni, Kuttenlochner, Wolfgang, Schreiber, Max, Kandler, Joshua, Alanjary, Mohammad, Mohiuddin, T M, Groll, Michael, Hochberg, Georg K A, Bode, Helge B
Published in Science (American Association for the Advancement of Science) (22.03.2024)
Published in Science (American Association for the Advancement of Science) (22.03.2024)
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Journal Article
Structure of Staphylococcus aureus ClpP Bound to the Covalent Active‐Site Inhibitor Cystargolide A
Illigmann, Astrid, Vielberg, Marie‐Theres, Lakemeyer, Markus, Wolf, Felix, Dema, Taulant, Stange, Patrik, Kuttenlochner, Wolfgang, Liebhart, Elisa, Kulik, Andreas, Staudt, Nicole D., Malik, Imran, Grond, Stephanie, Sieber, Stephan A., Kaysser, Leonard, Groll, Michael, Brötz‐Oesterhelt, Heike
Published in Angewandte Chemie International Edition (15.01.2024)
Published in Angewandte Chemie International Edition (15.01.2024)
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Journal Article
Bioengineering of syrbactin megasynthetases for immunoproteasome inhibitor production
Präve, Leonard, Kuttenlochner, Wolfgang, Tabak, Werner W.A., Langer, Chiara, Kaiser, Markus, Groll, Michael, Bode, Helge B.
Published in Chem (10.10.2024)
Published in Chem (10.10.2024)
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Journal Article
Optical Control of Proteasomal Protein Degradation with a Photoswitchable Lipopeptide
Morstein, Johannes, Amatuni, Alexander, Shuster, Anton, Kuttenlochner, Wolfgang, Ko, Tongil, Abegg, Daniel, Groll, Michael, Adibekian, Alexander, Renata, Hans, Trauner, Dirk H.
Published in Angewandte Chemie (19.02.2024)
Published in Angewandte Chemie (19.02.2024)
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Journal Article
Structure of Staphylococcus aureus ClpP Bound to the Covalent Active‐Site Inhibitor Cystargolide A
Illigmann, Astrid, Vielberg, Marie‐Theres, Lakemeyer, Markus, Wolf, Felix, Dema, Taulant, Stange, Patrik, Kuttenlochner, Wolfgang, Liebhart, Elisa, Kulik, Andreas, Staudt, Nicole D., Malik, Imran, Grond, Stephanie, Sieber, Stephan A., Kaysser, Leonard, Groll, Michael, Brötz‐Oesterhelt, Heike
Published in Angewandte Chemie (15.01.2024)
Published in Angewandte Chemie (15.01.2024)
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Journal Article
Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria
Yi-Ming, Shi, Hirschmann, Merle, Yan-Ni, Shi, Ahmed, Shabbir, Desalegne Abebew, Tobias, Nicholas J, Gruen, Peter, Crames, Jan J, Poeschel, Laura, Kuttenlochner, Wolfgang, Richter, Christian, Herrmann, Jennifer, Mueller, Rolf, Thanwisai, Aunchalee, Pidot, Sacha J, Stinear, Timothy P, Groll, Michael, Kim, Yonggyun, Bode, Helge B
Published in bioRxiv (21.01.2022)
Published in bioRxiv (21.01.2022)
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