Synergistic effects of sulopenem in combination with cefuroxime or durlobactam against Mycobacterium abscessus
Dousa, Khalid M, Shin, Eunjeong, Kurz, Sebastian G, Plummer, Mark, Nantongo, Mary, Bethel, Christopher R, Taracila, Magdalena A, Nguyen, David C, Kreiswith, Barry N, Daley, Charles L, Remy, Kenneth E, Holland, Steven M, Bonomo, Robert A
Published in mBio (14.05.2024)
Published in mBio (14.05.2024)
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Inhibiting Mycobacterium abscessus Cell Wall Synthesis: Using a Novel Diazabicyclooctane β-Lactamase Inhibitor To Augment β-Lactam Action
Dousa, Khalid M, Nguyen, David C, Kurz, Sebastian G, Taracila, Magdalena A, Bethel, Christopher R, Schinabeck, William, Kreiswirth, Barry N, Brown, Sheldon T, Boom, W Henry, Hotchkiss, Richard S, Remy, Kenneth E, Jacono, Frank J, Daley, Charles L, Holland, Steven M, Miller, Alita A, Bonomo, Robert A
Published in mBio (22.02.2022)
Published in mBio (22.02.2022)
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Can Inhibitor-Resistant Substitutions in the Mycobacterium tuberculosis β-Lactamase BlaC Lead to Clavulanate Resistance?: a Biochemical Rationale for the Use of β-Lactam–β-Lactamase Inhibitor Combinations
Kurz, Sebastian G, Wolff, Kerstin A, Hazra, Saugata, Bethel, Christopher R, Hujer, Andrea M, Smith, Kerri M, Xu, Yan, Tremblay, Lee W, Blanchard, John S, Nguyen, Liem, Bonomo, Robert A
Published in Antimicrobial Agents and Chemotherapy (01.12.2013)
Published in Antimicrobial Agents and Chemotherapy (01.12.2013)
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The effect of respiratory viral assay panel on antibiotic prescription patterns at discharge in adults admitted with mild to moderate acute exacerbation of COPD: a retrospective before- after study
Tickoo, Mayanka, Ruthazer, Robin, Bardia, Amit, Doron, Shira, Andujar-Vazquez, Gabriela M, Gardiner, Bradley J, Snydman, David R, Kurz, Sebastian G
Published in BMC pulmonary medicine (01.07.2019)
Published in BMC pulmonary medicine (01.07.2019)
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Journal Article
Drug-Resistant Tuberculosis: Challenges and Progress
Kurz, Sebastian G, Furin, Jennifer J, Bark, Charles M
Published in Infectious disease clinics of North America (01.06.2016)
Published in Infectious disease clinics of North America (01.06.2016)
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Journal Article
"One-Two Punch": Synergistic ß-Lactam Combinations for Mycobacterium abscessus and Target Redundancy in the Inhibition of Peptidoglycan Synthesis Enzymes
Nguyen, David C, Dousa, Khalid M, Kurz, Sebastian G, Brown, Sheldon T, Drusano, George, Holland, Steven M, Kreiswirth, Barry N, Boom, W Henry, Daley, Charles L, Bonomo, Robert A
Published in Clinical infectious diseases (20.10.2021)
Published in Clinical infectious diseases (20.10.2021)
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Insights into the l,d-Transpeptidases and d,d-Carboxypeptidase of Mycobacterium abscessus: Ceftaroline, Imipenem, and Novel Diazabicyclooctane Inhibitors
Dousa, Khalid M, Kurz, Sebastian G, Taracila, Magdalena A, Bonfield, Tracey, Bethel, Christopher R, Barnes, Melissa D, Selvaraju, Suresh, Abdelhamed, Ayman M, Kreiswirth, Barry N, Boom, W Henry, Kasperbauer, Shannon H, Daley, Charles L, Bonomo, Robert A
Published in Antimicrobial agents and chemotherapy (22.07.2020)
Published in Antimicrobial agents and chemotherapy (22.07.2020)
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Journal Article
Kinetic and Structural Characterization of the Interaction of 6‑Methylidene Penem 2 with the β‑Lactamase from Mycobacterium tuberculosis
Hazra, Saugata, Kurz, Sebastian G, Wolff, Kerstin, Nguyen, Liem, Bonomo, Robert A, Blanchard, John S
Published in Biochemistry (Easton) (15.09.2015)
Published in Biochemistry (Easton) (15.09.2015)
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Journal Article
Eradicating Pulmonary Mycobacterium abscessus: The Promise of Dual β-Lactam Therapy
Alahmdi, Bayan, Dousa, Khalid M, Kurz, Sebastian G, Kaufman, Andrew, Bonomo, Robert A, Taimur, Sarah
Published in Open forum infectious diseases (01.06.2023)
Published in Open forum infectious diseases (01.06.2023)
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Reappraising the use of β-lactams to treat tuberculosis
Kurz, Sebastian G, Bonomo, Robert A
Published in Expert review of anti-infective therapy (01.09.2012)
Published in Expert review of anti-infective therapy (01.09.2012)
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Durlobactam, a Diazabicyclooctane β‑Lactamase Inhibitor, Inhibits BlaC and Peptidoglycan Transpeptidases of Mycobacterium tuberculosis
Nantongo, Mary, Nguyen, David C., Bethel, Christopher R., Taracila, Magdalena A., Li, Qing, Dousa, Khalid M., Shin, Eunjeong, Kurz, Sebastian G., Nguyen, Liem, Kreiswirth, Barry N., Boom, W. Henry, Plummer, Mark S., Bonomo, Robert A.
Published in ACS infectious diseases (10.05.2024)
Published in ACS infectious diseases (10.05.2024)
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Summary for Clinicians: 2020 Clinical Practice Guideline Summary for the Treatment of Nontuberculous Mycobacterial Pulmonary Disease
Kurz, Sebastian G., Zha, B. Shoshana, Herman, Derrick D., Holt, Michael R., Daley, Charles L., Ruminjo, Joseph K., Thomson, Carey C.
Published in Annals of the American Thoracic Society (01.09.2020)
Published in Annals of the American Thoracic Society (01.09.2020)
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Inhibiting the β‑Lactamase of Mycobacterium tuberculosis (Mtb) with Novel Boronic Acid Transition-State Inhibitors (BATSIs)
Kurz, Sebastian G, Hazra, Saugata, Bethel, Christopher R, Romagnoli, Chiara, Caselli, Emilia, Prati, Fabio, Blanchard, John S, Bonomo, Robert A
Published in ACS infectious diseases (12.06.2015)
Published in ACS infectious diseases (12.06.2015)
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1642. A Novel β-lactamase Inhibitor (Durlobactam, DUR) and β-Lactams Enhance Susceptibility Against Multidrug-Resistant (MDR) Mycobacterium abscessus (Mab)
Dousa, Khalid M, Kurz, Sebastian G, Bethel, Christopher, Miller, Alita, Bonomo, Robert A
Published in Open forum infectious diseases (31.12.2020)
Published in Open forum infectious diseases (31.12.2020)
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1390. Durlobactam, a Diazabicyclooctane (DBO) β-lactamase Inhibitor (BLI), Inhibits BlaC and Peptidoglycan (PG) Transpeptidases of Mycobacterium tuberculosis (Mtb ): A Novel Approach to Therapeutics for Tuberculosis (TB)?
Nguyen, David, Bethel, Christopher, Taracilla, Magdalena A, Li, Qing, Dousa, Khalid M, Kurz, Sebastian G, Nguyen, Liem, Kreiswirth, Barry N, Boom, Wilem, Bonomo, Robert A
Published in Open forum infectious diseases (04.12.2021)
Published in Open forum infectious diseases (04.12.2021)
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1432. Exploring Cell Wall Targets to Overcome Mycobacterium tuberculosis (Mtb ): Ceftriaxone (CRO) Inhibits LdtMt2, a Major Peptidoglycan (PG) Synthase
Nguyen, David C, Redmond, Sarah N, Dousa, Khalid M, Bethel, Christopher, Taracila, Magdalena A, Li, Qing, Kurz, Sebastian G, Pavelka, Martin S, Papp-Wallace, Krisztina, Holland, Steven M, Kreiswirth, Barry N, Boom, Henry, Bonomo, Robert A
Published in Open forum infectious diseases (15.12.2022)
Published in Open forum infectious diseases (15.12.2022)
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