Search Results - "Kurt Hilpert" :: K.UTB vyhledávací portál

Identification of 2‑(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro‑1H‑pyrido[4,3‑b]indol-5(2H)‑yl)acetic Acid (Setipiprant/ACT-129968), a Potent, Selective, and Orally Bioavailable Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTH2) Antagonist

by Fretz, Heinz, Valdenaire, Anja, Pothier, Julien, Hilpert, Kurt, Gnerre, Carmela, Peter, Oliver, Leroy, Xavier, Riederer, Markus A
Published in Journal of medicinal chemistry (27.06.2013)

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Dose-dependent antithrombotic activity of an orally active tissue factor/factor VIIa inhibitor without concomitant enhancement of bleeding propensity

by Zbinden, Katrin Groebke, Banner, David W., Hilpert, Kurt, Himber, Jacques, Lavé, Thierry, Riederer, Markus A., Stahl, Martin, Tschopp, Thomas B., Obst-Sander, Ulrike
Published in Bioorganic & medicinal chemistry (01.08.2006)

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Selective and orally bioavailable phenylglycine tissue factor/factor VIIa inhibitors

by Zbinden, Katrin Groebke, Obst-Sander, Ulrike, Hilpert, Kurt, Kühne, Holger, Banner, David W., Böhm, Hans-Joachim, Stahl, Martin, Ackermann, Jean, Alig, Leo, Weber, Lutz, Wessel, Hans Peter, Riederer, Markus A., Tschopp, Thomas B., Lavé, Thierry
Published in Bioorganic & medicinal chemistry letters (01.12.2005)

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Design and Synthesis of Potent and Highly Selective Thrombin Inhibitors

by Hilpert, Kurt, Ackermann, Jean, Banner, David W., Gast, Alain, Gubernator, Klaus, Hadvary, Paul, Labler, Ludvik, Mueller, Klaus, Schmid, Gerard
Published in Journal of medicinal chemistry (01.11.1994)

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Discovery and Characterization of a New Class of C5aR1 Antagonists Showing In Vivo Activity

by Hubler, Francis, Renneberg, Dorte, Siendt, Hervé, Stamm, Simon, Hilpert, Kurt, Caroff, Eva, Delahaye, Stephane, Froidevaux, Sylvie, Murphy, Mark J.
Published in Journal of medicinal chemistry (14.03.2024)

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4‑((R)‑2-{[6-((S)‑3-Methoxypyrrolidin-1-yl)-2-phenylpyrimidine-4-carbonyl]amino}-3-phosphonopropionyl)piperazine-1-carboxylic Acid Butyl Ester (ACT-246475) and Its Prodrug (ACT-281959), a Novel P2Y12 Receptor Antagonist with a Wider Therapeutic Window in the Rat Than Clopidogrel

by Caroff, Eva, Hubler, Francis, Meyer, Emmanuel, Renneberg, Dorte, Gnerre, Carmela, Treiber, Alexander, Rey, Markus, Hess, Patrick, Steiner, Beat, Hilpert, Kurt, Riederer, Markus A
Published in Journal of medicinal chemistry (10.12.2015)

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Optimization of 2-phenyl-pyrimidine-4-carboxamides towards potent, orally bioavailable and selective P2Y12 antagonists for inhibition of platelet aggregation

by Caroff, Eva, Meyer, Emmanuel, Treiber, Alexander, Hilpert, Kurt, Riederer, Markus A.
Published in Bioorganic & medicinal chemistry letters (01.09.2014)

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Optimization of 2-phenyl-pyrimidine-4-carboxamides towards potent, orally bioavailable and selective P2Y(12) antagonists for inhibition of platelet aggregation

by Caroff, Eva, Meyer, Emmanuel, Treiber, Alexander, Hilpert, Kurt, Riederer, Markus A.
Published in Bioorganic & medicinal chemistry letters (01.09.2014)

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Discovery and Optimization of 4,5-Diarylisoxazoles as Potent Dual Inhibitors of Pyruvate Dehydrogenase Kinase and Heat Shock Protein 90

by Meng, Tao, Zhang, Dadong, Xie, Zuoquan, Yu, Ting, Wu, Shuchao, Wyder, Lorenza, Regenass, Urs, Hilpert, Kurt, Huang, Min, Geng, Meiyu, Shen, Jingkang
Published in Journal of medicinal chemistry (11.12.2014)

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Correction to “Discovery and Optimization of 4,5-Diarylisoxazoles as Potent Dual Inhibitors of Pyruvate Dehydrogenase Kinase and Heat Shock Protein 90”

by Meng, Tao, Zhang, Dadong, Xie, Zuoquan, Yu, Ting, Wu, Shuchao, Wyder, Lorenza, Regenass, Urs, Hilpert, Kurt, Huang, Min, Geng, Meiyu, Shen, Jingkang
Published in Journal of medicinal chemistry (12.12.2019)

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Identification of 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1 H -pyrido[4,3- b ]indol-5(2 H )-yl)acetic Acid (Setipiprant/ACT-129968), a Potent, Selective, and Orally Bioavailable Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTH2) Antagonist

by Fretz, Heinz, Valdenaire, Anja, Pothier, Julien, Hilpert, Kurt, Gnerre, Carmela, Peter, Oliver, Leroy, Xavier, Riederer, Markus A.
Published in Journal of medicinal chemistry (27.06.2013)

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Discovery of novel bridged tetrahydronaphthalene derivatives as potent T/L-type calcium channel blockers

by Renneberg, Dorte, Hubler, Francis, Rey, Markus, Hess, Patrick, Delahaye, Stephane, Gatfield, John, Iglarz, Marc, Hilpert, Kurt
Published in Bioorganic & medicinal chemistry letters (15.09.2015)

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4-(( R )-2-{[6-(( S )-3-Methoxypyrrolidin-1-yl)-2-phenylpyrimidine-4-carbonyl]amino}-3-phosphonopropionyl)piperazine-1-carboxylic Acid Butyl Ester (ACT-246475) and Its Prodrug (ACT-281959), a Novel P2Y 12 Receptor Antagonist with a Wider Therapeutic Window in the Rat Than Clopidogrel

by Caroff, Eva, Hubler, Francis, Meyer, Emmanuel, Renneberg, Dorte, Gnerre, Carmela, Treiber, Alexander, Rey, Markus, Hess, Patrick, Steiner, Beat, Hilpert, Kurt, Riederer, Markus A.
Published in Journal of medicinal chemistry (10.12.2015)

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