Serine 403 Phosphorylation of p62/SQSTM1 Regulates Selective Autophagic Clearance of Ubiquitinated Proteins
Matsumoto, Gen, Wada, Koji, Okuno, Misako, Kurosawa, Masaru, Nukina, Nobuyuki
Published in Molecular cell (21.10.2011)
Published in Molecular cell (21.10.2011)
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Nuclear localization of MBNL1: splicing-mediated autoregulation and repression of repeat-derived aberrant proteins
Kino, Yoshihiro, Washizu, Chika, Kurosawa, Masaru, Oma, Yoko, Hattori, Nobutaka, Ishiura, Shoichi, Nukina, Nobuyuki
Published in Human molecular genetics (01.02.2015)
Published in Human molecular genetics (01.02.2015)
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Distinct conformations of in vitro and in vivo amyloids of huntingtin-exon1 show different cytotoxicity
Nekooki-Machida, Yoko, Kurosawa, Masaru, Nukina, Nobuyuki, Ito, Kazuki, Oda, Toshiro, Tanaka, Motomasa
Published in Proceedings of the National Academy of Sciences - PNAS (16.06.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (16.06.2009)
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Intracellular localization and splicing regulation of FUS/TLS are variably affected by amyotrophic lateral sclerosis-linked mutations
Kino, Yoshihiro, Washizu, Chika, Aquilanti, Elisa, Okuno, Misako, Kurosawa, Masaru, Yamada, Mizuki, Doi, Hiroshi, Nukina, Nobuyuki
Published in Nucleic acids research (01.04.2011)
Published in Nucleic acids research (01.04.2011)
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Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein
Bauer, Peter O, Yamada, Mizuki, Wong, Hon Kit, Nukina, Nobuyuki, Kino, Yoshihiro, Miyazaki, Haruko, Kurosawa, Masaru, Okuno, Misako, Nagai, Yoshitaka, Matsumoto, Gen, Goswami, Anand
Published in Nature biotechnology (01.03.2010)
Published in Nature biotechnology (01.03.2010)
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Regulatory T Cells Exhibit Interleukin-33-Dependent Migratory Behavior during Skin Barrier Disruption
Toyama, Sumika, Moniaga, Catharina Sagita, Nakae, Susumu, Kurosawa, Masaru, Ogawa, Hideoki, Tominaga, Mitsutoshi, Takamori, Kenji
Published in International journal of molecular sciences (12.07.2021)
Published in International journal of molecular sciences (12.07.2021)
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FACS-array–based cell purification yields a specific transcriptome of striatal medium spiny neurons in a murine Huntington disease model
Miyazaki, Haruko, Yamanaka, Tomoyuki, Oyama, Fumitaka, Kino, Yoshihiro, Kurosawa, Masaru, Yamada-Kurosawa, Mizuki, Yamano, Risa, Shimogori, Tomomi, Hattori, Nobutaka, Nukina, Nobuyuki
Published in The Journal of biological chemistry (17.07.2020)
Published in The Journal of biological chemistry (17.07.2020)
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Depletion of p62 reduces nuclear inclusions and paradoxically ameliorates disease phenotypes in Huntington's model mice
Kurosawa, Masaru, Matsumoto, Gen, Kino, Yoshihiro, Okuno, Misako, Kurosawa-Yamada, Mizuki, Washizu, Chika, Taniguchi, Harumi, Nakaso, Kazuhiro, Yanagawa, Toru, Warabi, Eiji, Shimogori, Tomomi, Sakurai, Takashi, Hattori, Nobutaka, Nukina, Nobuyuki
Published in Human molecular genetics (15.02.2015)
Published in Human molecular genetics (15.02.2015)
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KIF11 as a Potential Marker of Spermatogenesis Within Mouse Seminiferous Tubule Cross-sections
Hara-Yokoyama, Miki, Kurihara, Hidetake, Ichinose, Shozo, Matsuda, Hironori, Ichinose, Shizuko, Kurosawa, Masaru, Tada, Norihiro, Iwahara, Chihiro, Terasawa, Kazue, Podyma-Inoue, Katarzyna A., Furukawa, Koichi, Iwabuchi, Kazuhisa
Published in The journal of histochemistry and cytochemistry (01.11.2019)
Published in The journal of histochemistry and cytochemistry (01.11.2019)
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Rapid dissemination of alpha-synuclein seeds through neural circuits in an in-vivo prion-like seeding experiment
Okuzumi, Ayami, Kurosawa, Masaru, Hatano, Taku, Takanashi, Masashi, Nojiri, Shuuko, Fukuhara, Takeshi, Yamanaka, Tomoyuki, Miyazaki, Haruko, Yoshinaga, Saki, Furukawa, Yoshiaki, Shimogori, Tomomi, Hattori, Nobutaka, Nukina, Nobuyuki
Published in Acta neuropathologica communications (19.09.2018)
Published in Acta neuropathologica communications (19.09.2018)
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Aggregation of scaffolding protein DISC1 dysregulates phosphodiesterase 4 in Huntington's disease
Tanaka, Motomasa, Ishizuka, Koko, Nekooki-Machida, Yoko, Endo, Ryo, Takashima, Noriko, Sasaki, Hideyuki, Komi, Yusuke, Gathercole, Amy, Huston, Elaine, Ishii, Kazuhiro, Hui, Kelvin Kai-Wan, Kurosawa, Masaru, Kim, Sun-Hong, Nukina, Nobuyuki, Takimoto, Eiki, Houslay, Miles D, Sawa, Akira
Published in The Journal of clinical investigation (01.04.2017)
Published in The Journal of clinical investigation (01.04.2017)
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TMEM30A is a candidate interacting partner for the β-carboxyl-terminal fragment of amyloid-β precursor protein in endosomes
Takasugi, Nobumasa, Araya, Runa, Kamikubo, Yuji, Kaneshiro, Nanaka, Imaoka, Ryosuke, Jin, Hao, Kashiyama, Taku, Hashimoto, Yoshie, Kurosawa, Masaru, Uehara, Takashi, Nukina, Nobuyuki, Sakurai, Takashi
Published in PloS one (07.08.2018)
Published in PloS one (07.08.2018)
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Serine 403-phosphorylated p62/SQSTM1 immunoreactivity in inclusions of neurodegenerative diseases
Kurosawa, Masaru, Matsumoto, Gen, Sumikura, Hiroyuki, Hatsuta, Hiroyuki, Murayama, Shigeo, Sakurai, Takashi, Shimogori, Tomomi, Hattori, Nobutaka, Nukina, Nobuyuki
Published in Neuroscience research (01.02.2016)
Published in Neuroscience research (01.02.2016)
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FUS/TLS deficiency causes behavioral and pathological abnormalities distinct from amyotrophic lateral sclerosis
Kino, Yoshihiro, Washizu, Chika, Kurosawa, Masaru, Yamada, Mizuki, Miyazaki, Haruko, Akagi, Takumi, Hashikawa, Tsutomu, Doi, Hiroshi, Takumi, Toru, Hicks, Geoffrey G, Hattori, Nobutaka, Shimogori, Tomomi, Nukina, Nobuyuki
Published in Acta neuropathologica communications (25.04.2015)
Published in Acta neuropathologica communications (25.04.2015)
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Journal Article
NF-Y inactivation causes atypical neurodegeneration characterized by ubiquitin and p62 accumulation and endoplasmic reticulum disorganization
Yamanaka, Tomoyuki, Tosaki, Asako, Kurosawa, Masaru, Matsumoto, Gen, Koike, Masato, Uchiyama, Yasuo, Maity, Sankar N, Shimogori, Tomomi, Hattori, Nobutaka, Nukina, Nobuyuki
Published in Nature communications (25.02.2014)
Published in Nature communications (25.02.2014)
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Journal Article
Blocking acid-sensing ion channel 1 alleviates Huntington's disease pathology via an ubiquitin-proteasome system-dependent mechanism
Wong, Hon Kit, Bauer, Peter O., Kurosawa, Masaru, Goswami, Anand, Washizu, Chika, Machida, Yoko, Tosaki, Asako, Yamada, Mizuki, Knöpfel, Thomas, Nakamura, Takemichi, Nukina, Nobuyuki
Published in Human molecular genetics (15.10.2008)
Published in Human molecular genetics (15.10.2008)
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RNA-binding Protein TLS Is a Major Nuclear Aggregate-interacting Protein in Huntingtin Exon 1 with Expanded Polyglutamine-expressing Cells
Doi, Hiroshi, Okamura, Kazumasa, Bauer, Peter O., Furukawa, Yoshiaki, Shimizu, Hideaki, Kurosawa, Masaru, Machida, Yoko, Miyazaki, Haruko, Mitsui, Kenichi, Kuroiwa, Yoshiyuki, Nukina, Nobuyuki
Published in The Journal of biological chemistry (07.03.2008)
Published in The Journal of biological chemistry (07.03.2008)
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