p70S6K/Akt dual inhibitor DIACC3010 is efficacious in preclinical models of gastric cancer alone and in combination with trastuzumab
Fukuoka, Shota, Koga, Yoshikatsu, Yamauchi, Mayumi, Koganemaru, Shigehiro, Yasunaga, Masahiro, Shitara, Kohei, Doi, Toshihiko, Yoshino, Takayuki, Kuronita, Toshio, Elenbaas, Brian, Wahra, Pamela, Zhang, Hong, Crowley, Lindsey, Jenkins, Molly H., Clark, Anderson, Kojima, Takashi
Published in Scientific reports (25.09.2023)
Published in Scientific reports (25.09.2023)
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Journal Article
A role for the lysosomal membrane protein LGP85 in the biogenesis and maintenance of endosomal and lysosomal morphology
Kuronita, Toshio, Eskelinen, Eeva-Liisa, Fujita, Hideaki, Saftig, Paul, Himeno, Masaru, Tanaka, Yoshitaka
Published in Journal of cell science (01.11.2002)
Published in Journal of cell science (01.11.2002)
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Journal Article
The NH2‐Terminal Transmembrane and Lumenal Domains of LGP85 are Needed for the Formation of Enlarged Endosomes/Lysosomes
Kuronita, Toshio, Hatano, Toshiyuki, Furuyama, Atsuko, Hirota, Yuko, Masuyama, Naoko, Saftig, Paul, Himeno, Masaru, Fujita, Hideaki, Tanaka, Yoshitaka
Published in Traffic (Copenhagen, Denmark) (01.10.2005)
Published in Traffic (Copenhagen, Denmark) (01.10.2005)
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3-Methyladenine specifically inhibits retrograde transport of cation-independent mannose 6-phosphate/insulin-like growth factor II receptor from the early endosome to the TGN
Hirosako, Kaori, Imasato, Hiroshi, Hirota, Yuko, Kuronita, Toshio, Masuyama, Naoko, Nishioka, Misa, Umeda, Atsushi, Fujita, Hideaki, Himeno, Masaru, Tanaka, Yoshitaka
Published in Biochemical and biophysical research communications (09.04.2004)
Published in Biochemical and biophysical research communications (09.04.2004)
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Journal Article
Distribution and trafficking of MPR300 is normal in cells with cholesterol accumulated in late endocytic compartments
Umeda, Atsushi, Fujita, Hideaki, Kuronita, Toshio, Hirosako, Kaori, Himeno, Masaru, Tanaka, Yoshitaka
Published in Journal of lipid research (01.10.2003)
Published in Journal of lipid research (01.10.2003)
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Journal Article
HM1.24 Is Internalized from Lipid Rafts by Clathrin-mediated Endocytosis through Interaction with α-Adaptin
Masuyama, Naoko, Kuronita, Toshio, Tanaka, Rika, Muto, Tomonori, Hirota, Yuko, Takigawa, Azusa, Fujita, Hideaki, Aso, Yoshinori, Amano, Jun, Tanaka, Yoshitaka
Published in The Journal of biological chemistry (05.06.2009)
Published in The Journal of biological chemistry (05.06.2009)
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Abstract 2935: Preclinical efficacy of the p70S6K/AKT dual inhibitor M2698 in combination with trastuzumab in models of gastric cancer
Fukuoka, Shota, Kojima, Takashi, Koga, Yoshikatsu, Yamauchi, Mayumi, Yasunaga, Masahiro, Matsumura, Yasuhiro, Shitara, Kohei, Doi, Toshihiko, Yoshino, Takayuki, Kuronita, Toshio, Clark, Anderson, Elenbaas, Brian, Zhang, Hong, Ohtsu, Atsushi
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Abstract 139: M2698, a novel dual inhibitor of p70S6K and Akt: preclinical efficacy in gastric cancer
Fukuoka, Shota, Kojima, Takashi, Koga, Yoshikatsu, Yamauchi, Mayumi, Yasunaga, Masahiro, Matsumura, Yasuhiro, Doi, Toshihiko, Yoshino, Takayuki, Kuronita, Toshio, Clark, Anderson, Elenbaas, Brian, Ohtsu, Atsuhi
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Abstract A126: Immunohistochemical analysis of integrin αv families in solid tumors
Kuboki, Yasutoshi, Nakamura, Yuka, Kuwata, Takeshi, Fujii, Satoshi, Kojima, Motohiro, Kuronita, Toshio, Watanabe, Morihiro, Straub, Josef, Ochiai, Atsushi
Published in Molecular cancer therapeutics (01.12.2015)
Published in Molecular cancer therapeutics (01.12.2015)
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Abstract 1669: Preclinical efficacy of Sym004, novel anti-EGFR antibody, in esophageal squamous cell carcinoma cell lines
Fukuoka, Shota, Kojima, Takashi, Koga, Yoshikatsu, Yamauchi, Mayumi, Komatsuzaki, Rie, Aoyagi, Kazuhiko, Sasaki, Hiroki, Yasunaga, Masahiro, Matsumura, Yasuhiro , Kuronita, Toshio, Doi, Toshihiko, Ohtsu, Atsushi
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
HM1.24 Is Internalized from Lipid Rafts by Clathrin-mediated Endocytosis through Interaction with α-Adaptin
Naoko Masuyama, Toshio Kuronita, Rika Tanaka, Tomonori Muto, Yuko Hirota, Azusa Takigawa, Hideaki Fujita, Yoshinori Aso, Jun Amano, Yoshitaka Tanaka
Published in The Journal of biological chemistry (05.06.2009)
Published in The Journal of biological chemistry (05.06.2009)
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Journal Article
The role of lysosomal membrane glycoproteins
Kuronita, Toshio, Himeno, Masaru, Tanaka, Yoshitaka
Published in Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme (01.05.2004)
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Published in Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme (01.05.2004)
Journal Article
Distribution and trafficking of MPR300 is normal in cells with cholesterol accumulated in late endocytic compartments: evidence for early endosome-to-TGN trafficking of MPR300
Umeda, Atsushi, Fujita, Hideaki, Kuronita, Toshio, Hirosako, Kaori, Himeno, Masaru, Tanaka, Yoshitaka
Published in Journal of lipid research (01.10.2003)
Published in Journal of lipid research (01.10.2003)
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Journal Article
Analysis of post-lysosomal compartments
Hirota, Yuko, Masuyama, Naoko, Kuronita, Toshio, Fujita, Hideaki, Himeno, Masaru, Tanaka, Yoshitaka
Published in Biochemical and biophysical research communications (06.02.2004)
Published in Biochemical and biophysical research communications (06.02.2004)
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Journal Article
The NH(2)-terminal transmembrane and lumenal domains of LGP85 are needed for the formation of enlarged endosomes/lysosomes
Kuronita, Toshio, Hatano, Toshiyuki, Furuyama, Atsuko, Hirota, Yuko, Masuyama, Naoko, Saftig, Paul, Himeno, Masaru, Fujita, Hideaki, Tanaka, Yoshitaka
Published in Traffic (Copenhagen, Denmark) (01.10.2005)
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Published in Traffic (Copenhagen, Denmark) (01.10.2005)
Journal Article
The NH 2 ‐Terminal Transmembrane and Lumenal Domains of LGP85 are Needed for the Formation of Enlarged Endosomes/Lysosomes
Kuronita, Toshio, Hatano, Toshiyuki, Furuyama, Atsuko, Hirota, Yuko, Masuyama, Naoko, Saftig, Paul, Himeno, Masaru, Fujita, Hideaki, Tanaka, Yoshitaka
Published in Traffic (Copenhagen, Denmark) (01.10.2005)
Published in Traffic (Copenhagen, Denmark) (01.10.2005)
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Journal Article