Gilteritinib, a FLT3/AXL inhibitor, shows antileukemic activity in mouse models of FLT3 mutated acute myeloid leukemia
Mori, Masamichi, Kaneko, Naoki, Ueno, Yoko, Yamada, Masaki, Tanaka, Ruriko, Saito, Rika, Shimada, Itsuro, Mori, Kenichi, Kuromitsu, Sadao
Published in Investigational new drugs (01.10.2017)
Published in Investigational new drugs (01.10.2017)
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Journal Article
ASP5878, a Novel Inhibitor of FGFR1, 2, 3, and 4, Inhibits the Growth of FGF19-Expressing Hepatocellular Carcinoma
Futami, Takashi, Okada, Hidetsugu, Kihara, Rumi, Kawase, Tatsuya, Nakayama, Ayako, Suzuki, Tomoyuki, Kameda, Minoru, Shindoh, Nobuaki, Terasaka, Tadashi, Hirano, Masaaki, Kuromitsu, Sadao
Published in Molecular cancer therapeutics (01.01.2017)
Published in Molecular cancer therapeutics (01.01.2017)
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Journal Article
Correlation analysis of the proportion of monocytic myeloid-derived suppressor cells in colorectal cancer patients
Shirasuna, Kenna, Ito, Masayuki, Matsuda, Takashi, Enomoto, Tsuyoshi, Ohara, Yusuke, Yamamoto, Masayoshi, Nishijima, Satomi, Ohkohchi, Nobuhiro, Kuromitsu, Sadao
Published in PloS one (28.12.2020)
Published in PloS one (28.12.2020)
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Journal Article
Sphingosine-1-phosphate receptor 1/5 selective agonist alleviates ocular vascular pathologies
Nakamura, Shinsuke, Yamamoto, Rie, Matsuda, Takaya, Yasuda, Hiroto, Nishinaka, Anri, Takahashi, Kei, Inoue, Yuki, Kuromitsu, Sadao, Shimazawa, Masamitsu, Goto, Masahide, Narumiya, Shuh, Hara, Hideaki
Published in Scientific reports (27.04.2024)
Published in Scientific reports (27.04.2024)
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Journal Article
The selective anaplastic lymphoma receptor tyrosine kinase inhibitor ASP3026 induces tumor regression and prolongs survival in non-small cell lung cancer model mice
Mori, Masamichi, Ueno, Yoko, Konagai, Satoshi, Fushiki, Hiroshi, Shimada, Itsuro, Kondoh, Yutaka, Saito, Rika, Mori, Kenichi, Shindou, Nobuaki, Soga, Takatoshi, Sakagami, Hideki, Furutani, Takashi, Doihara, Hitoshi, Kudoh, Masafumi, Kuromitsu, Sadao
Published in Molecular cancer therapeutics (01.02.2014)
Published in Molecular cancer therapeutics (01.02.2014)
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Journal Article
Upregulation of TRPC1 in the development of cardiac hypertrophy
Ohba, Takayoshi, Watanabe, Hiroyuki, Murakami, Manabu, Takahashi, Yoichiro, Iino, Kenji, Kuromitsu, Sadao, Mori, Yasuo, Ono, Kyoichi, Iijima, Toshihiko, Ito, Hiroshi
Published in Journal of molecular and cellular cardiology (01.03.2007)
Published in Journal of molecular and cellular cardiology (01.03.2007)
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Journal Article
ASP5878, a selective FGFR inhibitor, to treat FGFR3‐dependent urothelial cancer with or without chemoresistance
Kikuchi, Aya, Suzuki, Tomoyuki, Nakazawa, Taisuke, Iizuka, Masateru, Nakayama, Ayako, Ozawa, Tohru, Kameda, Minoru, Shindoh, Nobuaki, Terasaka, Tadashi, Hirano, Masaaki, Kuromitsu, Sadao
Published in Cancer science (01.02.2017)
Published in Cancer science (01.02.2017)
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Journal Article
Abstract 2586: ASP8273 selectively inhibits mutant EGFR signal pathway and induces tumor shrinkage in EGFR mutated tumor models
Konagai, Satoshi, Sakagami, Hideki, Yamamoto, Hiroko, Tanaka, Hiroaki, Matsuya, Takahiro, Mimasu, Shinya, Tomimoto, Yusuke, Mori, Masamichi, Koshio, Hiroyuki, Hirano, Masaaki, Kuromitsu, Sadao, Takeuchi, Masahiro
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Abstract B188: Preclinical antitumor activity of ASP8273, a mutant-selective irreversible EGFR inhibitor in an AXL-overexpressing NSCLC model
Kaneko, Naoki, Tanaka, Hiroaki, Konagai, Satoshi, Yamamoto, Hiroko, Sakagami, Hideki, Eguchi, Tomohiro, Matsuya, Takahiro, Mori, Masamichi, Koshio, Hiroyuki, Terasaka, Tadashi, Hirano, Masaaki, Kuromitsu, Sadao, Takeuchi, Masahiro
Published in Molecular cancer therapeutics (01.12.2015)
Published in Molecular cancer therapeutics (01.12.2015)
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Journal Article
Synthesis and evaluation of 2-{[2-(4-hydroxyphenyl)-ethyl]amino}pyrimidine-5-carboxamide derivatives as novel STAT6 inhibitors
Nagashima, Shinya, Yokota, Masaki, Nakai, Ei-ichi, Kuromitsu, Sadao, Ohga, Keiko, Takeuchi, Makoto, Tsukamoto, Shin-ichi, Ohta, Mitsuaki
Published in Bioorganic & medicinal chemistry (15.01.2007)
Published in Bioorganic & medicinal chemistry (15.01.2007)
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Journal Article
Abstract 866: ASP3026, a selective ALK inhibitor, induces tumor regression in a crizotinib-refractory model and prolongs survival in an intrapleurally xenograft model
Mori, Masamichi, Kuromitsu, Sadao, Ueno, Yoko, Tanaka, Ruriko, Shimada, Itsuro, Kondoh, Yutaka, Konagai, Satoshi, Sakagami, Hideki, Fushiki, Hiroshi, Saito, Rika, Sengoku, Takanori
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Journal Article
Abstract A227: Antitumor activities of ASP3026 against EML4-ALK-dependent tumor models
Kuromitsu, Sadao, Mori, Masamichi, Shimada, Itsuo, Kondoh, Yutaka, Shindoh, Nobuaki, Soga, Takatoshi, Furutani, Takashi, Konagai, Satoshi, Sakagami, Hideki, Nakata, Mari, Ueno, Yoko, Fushiki, Hiroshi, Saito, Rika, Sasamata, Masao, Mano, Hiroyuki, Kudou, Masafumi
Published in Molecular cancer therapeutics (12.11.2011)
Published in Molecular cancer therapeutics (12.11.2011)
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Abstract 2821: Anti-tumor activity of ASP3026, – A novel and selective ALK inhibitor
Kuromitsu, Sadao, Mori, Masamichi, Shimada, Itsuro, Kondoh, Yutaka, Shindoh, Nobuaki, Soga, Takatoshi, Furutani, Takashi, Konagai, Satoshi, Sakagami, Hideki, Nakata, Mari, Ueno, Yoko, Saito, Rika, Sasamata, Masao, Mano, Hiroyuki, Kudou, Masafumi
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Regulatory role of neuron-restrictive silencing factor in expression of TRPC1
Ohba, Takayoshi, Watanabe, Hiroyuki, Takahashi, Yoichiro, Suzuki, Takashi, Miyoshi, Ichiro, Nakayama, Shinnsuke, Satoh, Eisaku, Iino, Kenji, Sasano, Hironobu, Mori, Yasuo, Kuromitsu, Sadao, Imagawa, Keiichi, Saito, Yoshihiko, Iijima, Toshihiko, Ito, Hiroshi, Murakami, Manabu
Published in Biochemical and biophysical research communications (22.12.2006)
Published in Biochemical and biophysical research communications (22.12.2006)
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YM-359445, an Orally Bioavailable Vascular Endothelial Growth Factor Receptor-2 Tyrosine Kinase Inhibitor, Has Highly Potent Antitumor Activity against Established Tumors
Amino, Nobuaki, Ideyama, Yukitaka, Yamano, Mayumi, Kuromitsu, Sadao, Tajinda, Katsuinori, Samizu, Kiyohiro, Hisamichi, Hiroyuki, Matsuhisa, Akira, Shirasuna, Kenna, Kudoh, Masafumi, Shibasaki, Masayuki
Published in Clinical cancer research (01.03.2006)
Published in Clinical cancer research (01.03.2006)
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Combination of MS Protein Identification and Bioassay of Chromatographic Fractions to Identify Biologically Active Substances from Complex Protein Sources
Kuromitsu, Sadao, Yokota, Hiroyuki, Hiramoto, Masashi, Yuri, Masatoshi, Naitou, Masanori, Nakamura, Naoto, Kawabata, Shigeki, Kobori, Masato, Katoh, Masao, Furuchi, Kiyoshi, Mita, Haruhisa, Yamada, Tetsuo
Published in Molecular & cellular proteomics (01.06.2009)
Published in Molecular & cellular proteomics (01.06.2009)
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YM-231146, a Novel Orally Bioavailable Inhibitor of Vascular Endothelial Growth Factor Receptor-2, Is Effective against Paclitaxel Resistant Tumors
Amino, Nobuaki, Ideyama, Yukitaka, Yamano, Mayumi, Kuromitsu, Sadao, Tajinda, Katsunori, Samizu, Kiyohiro, Matsuhisa, Akira, Shirasuna, Kenna, Kudoh, Masafumi, Shibasaki, Masayuki
Published in Biological & Pharmaceutical Bulletin (01.11.2005)
Published in Biological & Pharmaceutical Bulletin (01.11.2005)
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A covalent small molecule inhibitor of glutamate-oxaloacetate transaminase 1 impairs pancreatic cancer growth
Yoshida, Tomohiro, Yamasaki, Shingo, Kaneko, Osamu, Taoka, Naofumi, Tomimoto, Yusuke, Namatame, Ichiji, Yahata, Toshiko, Kuromitsu, Sadao, Cantley, Lewis C., Lyssiotis, Costas A.
Published in Biochemical and biophysical research communications (12.02.2020)
Published in Biochemical and biophysical research communications (12.02.2020)
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Journal Article
Identification of a novel oncogenic mutation of FGFR4 in gastric cancer
Futami, Takashi, Kawase, Tatsuya, Mori, Kenichi, Asaumi, Makoto, Kihara, Rumi, Shindoh, Nobuaki, Kuromitsu, Sadao
Published in Scientific reports (10.10.2019)
Published in Scientific reports (10.10.2019)
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