An immortalized adult human erythroid line facilitates sustainable and scalable generation of functional red cells
Trakarnsanga, Kongtana, Griffiths, Rebecca E., Wilson, Marieangela C., Blair, Allison, Satchwell, Timothy J., Meinders, Marjolein, Cogan, Nicola, Kupzig, Sabine, Kurita, Ryo, Nakamura, Yukio, Toye, Ashley M., Anstee, David J., Frayne, Jan
Published in Nature communications (14.03.2017)
Published in Nature communications (14.03.2017)
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Journal Article
Reticulocyte Maturation and Variant Red Blood Cells
Stevens-Hernandez, Christian J, Flatt, Joanna F, Kupzig, Sabine, Bruce, Lesley J
Published in Frontiers in physiology (07.03.2022)
Published in Frontiers in physiology (07.03.2022)
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Journal Article
Superior survival of ex vivo cultured human reticulocytes following transfusion into mice
Kupzig, Sabine, Parsons, Stephen F, Curnow, Elinor, Anstee, David J, Blair, Allison
Published in Haematologica (Roma) (01.03.2017)
Published in Haematologica (Roma) (01.03.2017)
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Journal Article
Protein distribution during human erythroblast enucleation in vitro
Bell, Amanda J, Satchwell, Timothy J, Heesom, Kate J, Hawley, Bethan R, Kupzig, Sabine, Hazell, Matthew, Mushens, Rosey, Herman, Andrew, Toye, Ashley M
Published in PloS one (02.04.2013)
Published in PloS one (02.04.2013)
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Journal Article
Epigenetic silencing of a Ca²⁺-regulated Ras GTPase-activating protein RASAL defines a new mechanism of Ras activation in human cancers
Jin, Hongchuan, Wang, Xian, Ying, Jianming, Wong, Ada H.Y, Cui, Yan, Srivastava, Gopesh, Shen, Zhong-Ying, Li, En-Min, Zhang, Qian, Jin, Jie, Kupzig, Sabine, Chan, Anthony T.C, Cullen, Peter J, Tao, Qian
Published in Proceedings of the National Academy of Sciences - PNAS (24.07.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (24.07.2007)
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Journal Article
The ins and outs of human reticulocyte maturation: Autophagy and the endosome/exosome pathway
Griffiths, Rebecca E., Kupzig, Sabine, Cogan, Nicola, Mankelow, Tosti J., Betin, Virginie M.S., Trakarnsanga, Kongtana, Massey, Edwin J., Parsons, Stephen F., Anstee, David J., Lane, Jon D.
Published in Autophagy (01.07.2012)
Published in Autophagy (01.07.2012)
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Journal Article
The Frequencies of Calcium Oscillations Are Optimized for Efficient Calcium-Mediated Activation of Ras and the ERK/MAPK Cascade
Kupzig, Sabine, Walker, Simon A., Cullen, Peter J., Snyder, Solomon H.
Published in Proceedings of the National Academy of Sciences - PNAS (24.05.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (24.05.2005)
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Journal Article
Blood group type A secretors are associated with a higher risk of COVID‐19 cardiovascular disease complications
Mankelow, Tosti J., Singleton, Belinda K., Moura, Pedro L., Stevens‐Hernandez, Christian J., Cogan, Nicola M., Gyorffy, Gyongyver, Kupzig, Sabine, Nichols, Luned, Asby, Claire, Pooley, Jennifer, Ruffino, Gabriella, Hosseini, Faroakh, Moghaddas, Fiona, Attwood, Marie, Noel, Alan, Cooper, Alex, Arnold, David T., Hamilton, Fergus, Hyams, Catherine, Finn, Adam, Toye, Ashley M., Anstee, David J.
Published in EJHaem (01.05.2021)
Published in EJHaem (01.05.2021)
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Journal Article
Web Resource
GAP1 Family Members Constitute Bifunctional Ras and Rap GTPase-activating Proteins
Kupzig, Sabine, Deaconescu, Delia, Bouyoucef, Dalila, Walker, Simon A., Liu, Qing, Polte, Christian L., Daumke, Oliver, Ishizaki, Toshimasa, Lockyer, Peter J., Wittinghofer, Alfred, Cullen, Peter J.
Published in The Journal of biological chemistry (14.04.2006)
Published in The Journal of biological chemistry (14.04.2006)
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Journal Article
Identification of a Ras GTPase-activating protein regulated by receptor-mediated Ca2+ oscillations
Walker, Simon A, Kupzig, Sabine, Bouyoucef, Dalila, Davies, Louise C, Tsuboi, Takashi, Bivona, Trever G, Cozier, Gyles E, Lockyer, Peter J, Buckler, Alan, Rutter, Guy A, Allen, Maxine J, Philips, Mark R, Cullen, Peter J
Published in The EMBO journal (21.04.2004)
Published in The EMBO journal (21.04.2004)
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Journal Article
The Ability of GAP1IP4BP To Function as a Rap1 GTPase-Activating Protein (GAP) Requires Its Ras GAP-Related Domain and an Arginine Finger Rather than an Asparagine Thumb
Kupzig, Sabine, Bouyoucef-Cherchalli, Dalila, Yarwood, Sam, Sessions, Richard, Cullen, Peter J.
Published in Molecular and Cellular Biology (01.07.2009)
Published in Molecular and Cellular Biology (01.07.2009)
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Journal Article
Analyzing the Role of the Putative Inositol 1,3,4,5-Tetrakisphosphate Receptor GAP1IP4BP in Intracellular Ca2+ Homeostasis
Walker, Simon A, Kupzig, Sabine, Lockyer, Peter J, Bilu, Sara, Zharhary, Dorit, Cullen, Peter J
Published in The Journal of biological chemistry (13.12.2002)
Published in The Journal of biological chemistry (13.12.2002)
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Journal Article
Maturing reticulocytes internalize plasma membrane in glycophorin A–containing vesicles that fuse with autophagosomes before exocytosis
Griffiths, Rebecca E., Kupzig, Sabine, Cogan, Nicola, Mankelow, Tosti J., Betin, Virginie M.S., Trakarnsanga, Kongtana, Massey, Edwin J., Lane, Jon D., Parsons, Stephen F., Anstee, David J.
Published in Blood (28.06.2012)
Published in Blood (28.06.2012)
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Journal Article
Bst‐2/HM1.24 Is a Raft‐Associated Apical Membrane Protein with an Unusual Topology
Kupzig, Sabine, Korolchuk, Viktor, Rollason, Ruth, Sugden, Anna, Wilde, Andrew, Banting, George
Published in Traffic (Copenhagen, Denmark) (01.10.2003)
Published in Traffic (Copenhagen, Denmark) (01.10.2003)
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Journal Article
Identification of the Ras GTPase-activating protein GAP1m as a phosphatidylinositol-3,4,5-trisphosphate-binding protein in vivo
Lockyer, Peter J., Wennström, Stefan, Kupzig, Sabine, Venkateswarlu, Kanamarlapudi, Downward, Julian, Cullen, Peter J.
Published in Current biology (01.03.1999)
Published in Current biology (01.03.1999)
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Journal Article
Ex vivo Engineering of Red Blood Cells
Frayne, Jan, Daniels, Deborah E, Frayne, Jan, Satchwell, Timothy J, Hawksworth, Joseph, Singleton, Belinda K, Andrienko, Tatyana N, Wilson, Marieangela C, Kupzig, Sabine, Meinders, Marjolein, Kurita, Ryo, Nakamura, Yukio, Ferrer Vicens, Ivan, Griffiths, Rebecca, Cogan, Nicola, Trakarnsanga, Kongtana, Anstee, David J., Toye, Ashley Mark
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
GAP1IP4BP Contains a Novel Group I Pleckstrin Homology Domain That Directs Constitutive Plasma Membrane Association
Cozier, G E, Lockyer, P J, Reynolds, J S, Kupzig, S, Bottomley, J R, Millard, T H, Banting, G, Cullen, P J
Published in The Journal of biological chemistry (08.09.2000)
Published in The Journal of biological chemistry (08.09.2000)
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Journal Article
Epigenetic silencing of a Ca(2+)-regulated Ras GTPase-activating protein RASAL defines a new mechanism of Ras activation in human cancers
Jin, Hongchuan, Wang, Xian, Ying, Jianming, Wong, Ada H Y, Cui, Yan, Srivastava, Gopesh, Shen, Zhong-Ying, Li, En-Min, Zhang, Qian, Jin, Jie, Kupzig, Sabine, Chan, Anthony T C, Cullen, Peter J, Tao, Qian
Published in Proceedings of the National Academy of Sciences - PNAS (24.07.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (24.07.2007)
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Journal Article
Critical band 3 multiprotein complex interactions establish early during human erythropoiesis
Satchwell, Timothy J., Bell, Amanda J., Pellegrin, Stephanie, Kupzig, Sabine, Ridgwell, Kay, Daniels, Geoff, Anstee, David J., van den Akker, Emile, Toye, Ashley M.
Published in Blood (07.07.2011)
Published in Blood (07.07.2011)
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Journal Article