Target engagement and drug residence time can be observed in living cells with BRET
Robers, Matthew B., Dart, Melanie L., Woodroofe, Carolyn C., Zimprich, Chad A., Kirkland, Thomas A., Machleidt, Thomas, Kupcho, Kevin R., Levin, Sergiy, Hartnett, James R., Zimmerman, Kristopher, Niles, Andrew L., Ohana, Rachel Friedman, Daniels, Danette L., Slater, Michael, Wood, Monika G., Cong, Mei, Cheng, Yi-Qiang, Wood, Keith V.
Published in Nature communications (03.12.2015)
Published in Nature communications (03.12.2015)
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Journal Article
Tumor-suppressor role of Notch3 in medullary thyroid carcinoma revealed by genetic and pharmacological induction
Jaskula-Sztul, Renata, Eide, Jacob, Tesfazghi, Sara, Dammalapati, Ajitha, Harrison, April D, Yu, Xiao-Min, Scheinebeck, Casi, Winston-McPherson, Gabrielle, Kupcho, Kevin R, Robers, Matthew B, Hundal, Amrit K, Tang, Weiping, Chen, Herbert
Published in Molecular cancer therapeutics (01.02.2015)
Published in Molecular cancer therapeutics (01.02.2015)
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Journal Article
The Androgen Receptor T877A Mutant Recruits LXXLL and FXXLF Peptides Differently than Wild-Type Androgen Receptor in a Time-Resolved Fluorescence Resonance Energy Transfer Assay
Ozers, Mary Szatkowski, Marks, Bryan D, Gowda, Krishne, Kupcho, Kevin R, Ervin, Kerry M, De Rosier, Therese, Qadir, Naveeda, Eliason, Hildegard C, Riddle, Steven M, Shekhani, Mohammed Saleh
Published in Biochemistry (Easton) (23.01.2007)
Published in Biochemistry (Easton) (23.01.2007)
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Journal Article
Characterization of Phosphotyrosine Binding Motifs in the Cytoplasmic Domain of Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1) That Are Required for the Cellular Association and Activation of the Protein-tyrosine Phosphatase, SHP-2
Jackson, Denise E., Kupcho, Kevin R., Newman, Peter. J.
Published in The Journal of biological chemistry (03.10.1997)
Published in The Journal of biological chemistry (03.10.1997)
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Journal Article
Overcoming compound interference in fluorescence polarization-based kinase assays using far-red tracers
Vedvik, Kevin L, Eliason, Hildegard C, Hoffman, Randy L, Gibson, Jasmin R, Kupcho, Kevin R, Somberg, Richard L, Vogel, Kurt W
Published in Assay and drug development technologies (01.04.2004)
Published in Assay and drug development technologies (01.04.2004)
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Journal Article
Abstract 1933: Improved DAMP assays for the in vitro assessment of immunogenic cell death
Niles, Andrew L., Kupcho, Kevin R., Lazar, Dan F., Cali, James J.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Abstract 710: Real-time apoptosis and necrosis detection in 3D spheroid cellmodels
Niles, Andrew L., Kupcho, Kevin R., Riss, Terry L., Lazar, Dan F., Cali, James J.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Abstract 5595: Rapid and sensitive determination of cytokine release from cells without the need for sample transfer
Lazar, Dan F., Kupcho, Kevin R., Sondgeroth, Casey A., Thompson, David V., O'Brien, Martha A., Gilden, Julia K., Hsiao, Kevin, Cali, James J.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Rapid and sensitive determination of cytokine release from cells without the need for sample transfer
Lazar, Dan F, Kupcho, Kevin R, Sondgeroth, Casey A, Hsiao, Kevin, Thompson, David V, O’Brien, Martha A, Gilden, Julia K, Cali, James J
Published in The Journal of immunology (1950) (01.05.2020)
Published in The Journal of immunology (1950) (01.05.2020)
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Journal Article
Abstract 4237: Isoenzyme-selective HDAC activity assays
Kupcho, Kevin R., Evans, Nathan J., Niles, Andrew L., Lazar, Dan F., Kirkland, Thomas A.
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Journal Article
Abstract 3731: Luminescent cell health assays for tumor spheroid evaluation
Valley, Michael P., Kupcho, Kevin R., Zimprich, Chad A., Niles, Andrew L., Cali, James J., Kelm, Jens M., Moritz, Wolfgang, Lazar, Dan F.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
Fluorescent cascade and direct assays for characterization of RAF signaling pathway inhibitors
Kupcho, Kevin R, Bruinsma, Rica, Hallis, Tina M, Lasky, David A, Somberg, Richard L, Turek-Etienne, Tammy, Vogel, Kurt W, Huwiler, Kristin G
Published in Current chemical genomics (25.02.2008)
Published in Current chemical genomics (25.02.2008)
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Journal Article
Fluorescent Cascade and Direct Assays for Characterization of RAF Signaling Pathway Inhibitors
Kupcho, Kevin R, Bruinsma, Rica, Hallis, Tina M, Lasky, David A, Somberg, Richard L, Turek-Etienne, Tammy, Vogel, Kurt W, Huwiler, Kristin G
Published in Current chemical genomics (01.01.2007)
Published in Current chemical genomics (01.01.2007)
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Journal Article
Bimolecular optical probes
Kupcho, Kevin R, Vogel, Kurt, Werner, Elizabeth A, Beebe, Jane A, Klink, Tony A, Lasky, David A, Kleman-Leyer, Karen M, Somberg, Richard
Year of Publication 17.11.2009
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Year of Publication 17.11.2009
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