Xanthohumol increases death receptor 5 expression and enhances apoptosis with the TNF-related apoptosis-inducing ligand in neuroblastoma cell lines
Engelsgjerd, Samuel, Kunnimalaiyaan, Selvi, Kandil, Emad, Gamblin, T Clark, Kunnimalaiyaan, Muthusamy
Published in PloS one (14.03.2019)
Published in PloS one (14.03.2019)
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Journal Article
RAD51C-XRCC3 structure and cancer patient mutations define DNA replication roles
Longo, Michael A., Roy, Sunetra, Chen, Yue, Tomaszowski, Karl-Heinz, Arvai, Andrew S., Pepper, Jordan T., Boisvert, Rebecca A., Kunnimalaiyaan, Selvi, Keshvani, Caezanne, Schild, David, Bacolla, Albino, Williams, Gareth J., Tainer, John A., Schlacher, Katharina
Published in Nature communications (24.07.2023)
Published in Nature communications (24.07.2023)
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Journal Article
Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, alters multiple signaling pathways in hepatocellular carcinoma cell lines
Kunnimalaiyaan, Selvi, Sokolowski, Kevin, Gamblin, T. Clark, Kunnimalaiyaan, Muthusamy
Published in The American journal of surgery (01.04.2017)
Published in The American journal of surgery (01.04.2017)
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Journal Article
Potential Molecular Targeted Therapeutics: Role of PI3-K/Akt/mTOR Inhibition in Cancer
Sokolowski, Kevin M, Koprowski, Steven, Kunnimalaiyaan, Selvi, Balamurugan, Mariappan, Gamblin, T Clark, Kunnimalaiyaan, Muthusamy
Published in Anti-cancer agents in medicinal chemistry (01.01.2016)
Published in Anti-cancer agents in medicinal chemistry (01.01.2016)
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Journal Article
Curcumin-mediated regulation of Notch1/hairy and enhancer of split-1/survivin: molecular targeting in cholangiocarcinoma
Koprowski, Steven, BS, Sokolowski, Kevin, MD, Kunnimalaiyaan, Selvi, MS, Gamblin, T. Clark, MD, MS, Kunnimalaiyaan, Muthusamy, PhD
Published in The Journal of surgical research (01.10.2015)
Published in The Journal of surgical research (01.10.2015)
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Journal Article
Role of Akt inhibition on Notch1 expression in hepatocellular carcinoma: potential role for dual targeted therapy
Sokolowski, Kevin M., M.D, Balamurugan, Mariappan, Ph.D, Kunnimalaiyaan, Selvi, M.S, Wilson, Jacob, B.S, Gamblin, Thomas Clark, M.D., M.S., M.B.A., F.A.C.S, Kunnimalaiyaan, Muthusamy, Ph.D
Published in The American journal of surgery (01.04.2016)
Published in The American journal of surgery (01.04.2016)
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Journal Article
Role of π Dimers in Coupling (“Handcuffing”) of Plasmid R6K's γ ori Iterons
KUNNIMALAIYAAN, Selvi, INMAN, Ross B, RAKOWSKI, Sheryl A, FILUTOWICZ, Marcin
Published in Journal of Bacteriology (01.06.2005)
Published in Journal of Bacteriology (01.06.2005)
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Journal Article
Xanthohumol-Mediated Suppression of Notch1 Signaling Is Associated with Antitumor Activity in Human Pancreatic Cancer Cells
Kunnimalaiyaan, Selvi, Trevino, Jose, Tsai, Susan, Gamblin, T Clark, Kunnimalaiyaan, Muthusamy
Published in Molecular cancer therapeutics (01.06.2015)
Published in Molecular cancer therapeutics (01.06.2015)
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Journal Article
Abstract 7266: VGLL4 is the target of the 3p25 homozygous deletion and presents a novel therapeutic vulnerability for TEAD1/4 but not TEAD1 inhibitors
Muller, Florian, Kunnimalaiyaan, Selvi, Mangrolia, Parth, Olson, Jill
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Abstract 5913: TEAD1/4 inhibitors exhibit deeper biological impact and broader activity compared to TEAD1-only inhibitors in both monotherapy and combination without additional kidney toxicity
Muller, Florian, Kunnimalaiyaan, Selvi, Mangrolia, Parth, Olson, Jill
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma
Msaouel, Pavlos, Malouf, Gabriel G., Su, Xiaoping, Yao, Hui, Tripathi, Durga N., Soeung, Melinda, Gao, Jianjun, Rao, Priya, Coarfa, Cristian, Creighton, Chad J., Bertocchio, Jean-Philippe, Kunnimalaiyaan, Selvi, Multani, Asha S., Blando, Jorge, He, Rong, Shapiro, Daniel D., Perelli, Luigi, Srinivasan, Sanjana, Carbone, Federica, Pilié, Patrick G., Karki, Menuka, Seervai, Riyad N.H., Vokshi, Bujamin H., Lopez-Terrada, Dolores, Cheng, Emily H., Tang, Ximing, Lu, Wei, Wistuba, Ignacio I., Thompson, Timothy C., Davidson, Irwin, Giuliani, Virginia, Schlacher, Katharina, Carugo, Alessandro, Heffernan, Timothy P., Sharma, Padmanee, Karam, Jose A., Wood, Christopher G., Walker, Cheryl L., Genovese, Giannicola, Tannir, Nizar M.
Published in Cancer cell (11.05.2020)
Published in Cancer cell (11.05.2020)
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Journal Article
Abstract 5289: Role of notch3 in epithelial-to-mesenchymal transition of HCC
Kunnimalaiyaan, Selvi, Gamblin, T. Clark, Kunnimalaiyaan, Muthusamy
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
Antiproliferative and apoptotic effects of xanthohumol in cholangiocarcinoma
Walden, Daniel, Kunnimalaiyaan, Selvi, Sokolowski, Kevin, Clark, T Gamblin, Kunnimalaiyaan, Muthusamy
Published in Oncotarget (20.10.2017)
Published in Oncotarget (20.10.2017)
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Journal Article
MRE11-dependent instability in mitochondrial DNA fork protection activates a cGAS immune signaling pathway
Luzwick, Jessica W, Dombi, Eszter, Boisvert, Rebecca A, Roy, Sunetra, Park, Soyoung, Kunnimalaiyaan, Selvi, Goffart, Steffi, Schindler, Detlev, Schlacher, Katharina
Published in Science advances (17.12.2021)
Published in Science advances (17.12.2021)
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