Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
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Published in Chemical reviews (27.01.2016)
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Next generation organofluorine containing blockbuster drugs
Han, Jianlin, Remete, Attila Márió, Dobson, Luca S., Kiss, Lorand, Izawa, Kunisuke, Moriwaki, Hiroki, Soloshonok, Vadim A., O’Hagan, David
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Published in Journal of fluorine chemistry (01.11.2020)
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Recent advances in the trifluoromethylation methodology and new CF3-containing drugs
Zhu, Wei, Wang, Jiang, Wang, Shuni, Gu, Zhanni, Aceña, José Luis, Izawa, Kunisuke, Liu, Hong, Soloshonok, Vadim A.
Published in Journal of fluorine chemistry (01.11.2014)
Published in Journal of fluorine chemistry (01.11.2014)
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Applications of fluorine-containing amino acids for drug design
Mei, Haibo, Han, Jianlin, Klika, Karel D., Izawa, Kunisuke, Sato, Tatsunori, Meanwell, Nicholas A., Soloshonok, Vadim A.
Published in European journal of medicinal chemistry (15.01.2020)
Published in European journal of medicinal chemistry (15.01.2020)
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Tailor‐Made Amino Acids and Fluorinated Motifs as Prominent Traits in Modern Pharmaceuticals
Mei, Haibo, Han, Jianlin, White, Sarah, Graham, Daniel J., Izawa, Kunisuke, Sato, Tatsunori, Fustero, Santos, Meanwell, Nicholas A., Soloshonok, Vadim A.
Published in Chemistry : a European journal (04.09.2020)
Published in Chemistry : a European journal (04.09.2020)
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Fluorine-containing pharmaceuticals approved by the FDA in 2020: Synthesis and biological activity
Yu, Yingjie, Liu, Aiyao, Dhawan, Gagan, Mei, Haibo, Zhang, Wei, Izawa, Kunisuke, Soloshonok, Vadim A., Han, Jianlin
Published in Chinese chemical letters (01.11.2021)
Published in Chinese chemical letters (01.11.2021)
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Asymmetric Synthesis of Tailor-Made Amino Acids Using Chiral Ni(II) Complexes of Schiff Bases. An Update of the Recent Literature
Zou, Yupiao, Han, Jianlin, Saghyan, Ashot S, Mkrtchyan, Anna F, Konno, Hiroyuki, Moriwaki, Hiroki, Izawa, Kunisuke, Soloshonok, Vadim A
Published in Molecules (Basel, Switzerland) (12.06.2020)
Published in Molecules (Basel, Switzerland) (12.06.2020)
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Small-Molecule Therapeutics for Ebola Virus (EBOV) Disease Treatment
Izawa, Kunisuke, Aceña, José Luis, Wang, Jiang, Soloshonok, Vadim A., Liu, Hong
Published in European journal of organic chemistry (01.01.2016)
Published in European journal of organic chemistry (01.01.2016)
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The Second-generation of Highly Potent Hepatitis C Virus (HCV) NS3/4A Protease Inhibitors: Evolutionary Design Based on Tailor-made Amino Acids, Synthesis and Major Features of Bio-activity
Wang, Shuni, Wang, Yibing, Wang, Jiang, Sato, Tatsunori, Izawa, Kunisuke, Soloshonok, Vadim A, Liu, Hong
Published in Current pharmaceutical design (01.01.2017)
Published in Current pharmaceutical design (01.01.2017)
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Optical Resolution of Rimantadine
Han, Jianlin, Takeda, Ryosuke, Sato, Tatsunori, Moriwaki, Hiroki, Abe, Hidenori, Izawa, Kunisuke, Soloshonok, Vadim A
Published in Molecules (Basel, Switzerland) (12.05.2019)
Published in Molecules (Basel, Switzerland) (12.05.2019)
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Tandem Alkylation–Second-Order Asymmetric Transformation Protocol for the Preparation of Phenylalanine-Type Tailor-Made α‑Amino Acids
Takeda, Ryosuke, Kawashima, Aki, Yamamoto, Junya, Sato, Tatsunori, Moriwaki, Hiroki, Izawa, Kunisuke, Abe, Hidenori, Soloshonok, Vadim A
Published in ACS omega (31.08.2018)
Published in ACS omega (31.08.2018)
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Tailor-made amino acids in the design of small-molecule blockbuster drugs
Han, Jianlin, Konno, Hiroyuki, Sato, Tatsunori, Soloshonok, Vadim A., Izawa, Kunisuke
Published in European journal of medicinal chemistry (05.08.2021)
Published in European journal of medicinal chemistry (05.08.2021)
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Dynamic Thermodynamic Resolution of Unprotected Amino Acids Using Ni(II) Chiral Schiff Bases
Nakano, Arina, Hayashi, Akari, Nagaoka, Keita, Moriwaki, Hiroki, Izawa, Kunisuke, Yano, Shigekazu, Konno, Hiroyuki
Published in European journal of organic chemistry (23.09.2024)
Published in European journal of organic chemistry (23.09.2024)
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Tailor-Made α-Amino Acids in the Pharmaceutical Industry: Synthetic Approaches to (1R,2S)-1-Amino-2-vinylcyclopropane-1-carboxylic Acid (Vinyl-ACCA)
Sato, Tatsunori, Izawa, Kunisuke, Aceña, José Luis, Liu, Hong, Soloshonok, Vadim A.
Published in European journal of organic chemistry (01.06.2016)
Published in European journal of organic chemistry (01.06.2016)
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Tailor-made amino acid-derived pharmaceuticals approved by the FDA in 2019
Yin, Zizhen, Hu, Wenfei, Zhang, Wei, Konno, Hiroyuki, Moriwaki, Hiroki, Izawa, Kunisuke, Han, Jianlin, Soloshonok, Vadim A.
Published in Amino acids (01.09.2020)
Published in Amino acids (01.09.2020)
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New pharmaceuticals approved by FDA in 2020: Small‐molecule drugs derived from amino acids and related compounds
Liu, Aiyao, Han, Jianlin, Nakano, Arina, Konno, Hiroyuki, Moriwaki, Hiroki, Abe, Hidenori, Izawa, Kunisuke, Soloshonok, Vadim A.
Published in Chirality (New York, N.Y.) (01.01.2022)
Published in Chirality (New York, N.Y.) (01.01.2022)
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