Prodrugs: design and clinical applications
Rautio, Jarkko, Kumpulainen, Hanna, Heimbach, Tycho, Oliyai, Reza, Oh, Dooman, Järvinen, Tomi, Savolainen, Jouko
Published in Nature reviews. Drug discovery (01.03.2008)
Published in Nature reviews. Drug discovery (01.03.2008)
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Journal Article
Synthesis, in vitro and in vivo characterization of novel ethyl dioxy phosphate prodrug of propofol
Kumpulainen, Hanna, Järvinen, Tomi, Mannila, Anne, Leppänen, Jukka, Nevalainen, Tapio, Mäntylä, Antti, Vepsäläinen, Jouko, Rautio, Jarkko
Published in European journal of pharmaceutical sciences (03.07.2008)
Published in European journal of pharmaceutical sciences (03.07.2008)
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Journal Article
Synthesis, in uitro and in uiuo characterization of novel ethyl dioxy phosphate prodrug of propofol
KUMPULAINEN, Hanna, JÄRVINEN, Tomi, MANNILA, Anne, LEPPÄNEN, Jukka, NEVALAINEN, Tapio, MÄNTYLÄ, Antti, VEPSÄLÄINEN, Jouko, RAUTIO, Jarkko
Published in European journal of pharmaceutical sciences (2008)
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Published in European journal of pharmaceutical sciences (2008)
Journal Article
An Efficient Strategy for the Synthesis of 1-Chloroethyl Phosphates and Phosphoramidates
Kumpulainen, Hanna, Järvinen, Tomi, Saari, Raimo, Lehtonen, Marko, Vepsäläinen, Jouko
Published in Journal of organic chemistry (28.10.2005)
Published in Journal of organic chemistry (28.10.2005)
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Journal Article
Novel cyclic phosphate prodrug approach for cytochrome p450-activated drugs containing an alcohol functionality
HUTTUNEN, Kristiina M, MÄHÖNEN, Niina, LEPPÄNEN, Jukka, VEPSÄLÄINEN, Jouko, JUVONEN, Risto O, RAUNIO, Hannu, KUMPULAINEN, Hanna, JÄRVINEN, Tomi, RAUTIO, Jarkko
Published in Pharmaceutical research (01.04.2007)
Published in Pharmaceutical research (01.04.2007)
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Journal Article
Evaluation of Hydroxyimine as Cytochrome P450-Selective Prodrug Structure
Kumpulainen, Hanna, Mähönen, Niina, Laitinen, Marja-Leena, Jaurakkajärvi, Marja, Raunio, Hannu, Juvonen, Risto O, Vepsäläinen, Jouko, Järvinen, Tomi, Rautio, Jarkko
Published in Journal of medicinal chemistry (09.02.2006)
Published in Journal of medicinal chemistry (09.02.2006)
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Journal Article
Convenient microwave-assisted synthesis of 1-chloroethyl phosphates
Kumpulainen, Hanna, Saari, Raimo, Lehtonen, Marko, Rautio, Jarkko, Järvinen, Tomi, Vepsäläinen, Jouko
Published in Tetrahedron letters (20.03.2006)
Published in Tetrahedron letters (20.03.2006)
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Journal Article
Efficient strategy to prepare water-soluble prodrugs of ketones
Huttunen, KM, Kumpulainen, H, Leppanen, J, Rautio, J, Jarvinen, T, Vepsalainen, J
Published in Synlett (17.03.2006)
Published in Synlett (17.03.2006)
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Journal Article
Prodrugs: design and clinical applications
Rautio, Jarkko, Kumpulainen, Hanna, Heimbach, Tycho, Oliyai, Reza, Oh, Dooman, Järvinen, Tomi, Savolainen, Jouko
Published in Nature reviews. Drug discovery (01.03.2008)
Published in Nature reviews. Drug discovery (01.03.2008)
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Journal Article
An Efficient Strategy for the Synthesis of 1-Chloroethyl Phosphates and Phosphoramidates
Kumpulainen, Hanna, Jaervinen, Tomi, Saari, Raimo, Lehtonen, Marko, Vepsaelaeinen, Jouko
Published in ChemInform (14.03.2006)
Published in ChemInform (14.03.2006)
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Journal Article
Convenient Microwave-Assisted Synthesis of 1-Chloroethyl Phosphates
Kumpulainen, Hanna, Saari, Raimo, Lehtonen, Marko, Rautio, Jarkko, Jaervinen, Tomi, Vepsaelaeinen, Jouko
Published in ChemInform (27.06.2006)
Published in ChemInform (27.06.2006)
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Journal Article