Innate immune activation in neurodegenerative disease
Heneka, Michael T., Kummer, Markus P., Latz, Eicke
Published in Nature reviews. Immunology (01.07.2014)
Published in Nature reviews. Immunology (01.07.2014)
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Journal Article
PPARγ/RXRα-induced and CD36-mediated microglial amyloid-β phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice
Yamanaka, Mitsugu, Ishikawa, Taizo, Griep, Angelika, Axt, Daisy, Kummer, Markus P, Heneka, Michael T
Published in The Journal of neuroscience (28.11.2012)
Published in The Journal of neuroscience (28.11.2012)
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Journal Article
Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease
Venegas, Carmen, Kumar, Sathish, Franklin, Bernardo S., Dierkes, Tobias, Brinkschulte, Rebecca, Tejera, Dario, Vieira-Saecker, Ana, Schwartz, Stephanie, Santarelli, Francesco, Kummer, Markus P., Griep, Angelika, Gelpi, Ellen, Beilharz, Michael, Riedel, Dietmar, Golenbock, Douglas T., Geyer, Matthias, Walter, Jochen, Latz, Eicke, Heneka, Michael T.
Published in Nature (London) (21.12.2017)
Published in Nature (London) (21.12.2017)
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Journal Article
NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
Heneka, Michael T., Kummer, Markus P., Stutz, Andrea, Delekate, Andrea, Schwartz, Stephanie, Vieira-Saecker, Ana, Griep, Angelika, Axt, Daisy, Remus, Anita, Tzeng, Te-Chen, Gelpi, Ellen, Halle, Annett, Korte, Martin, Latz, Eicke, Golenbock, Douglas T.
Published in Nature (London) (31.01.2013)
Published in Nature (London) (31.01.2013)
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Journal Article
Nitration of Tyrosine 10 Critically Enhances Amyloid β Aggregation and Plaque Formation
Kummer, Markus P., Hermes, Michael, Delekarte, Andrea, Hammerschmidt, Thea, Kumar, Sathish, Terwel, Dick, Walter, Jochen, Pape, Hans-Christian, König, Simone, Roeber, Sigrun, Jessen, Frank, Klockgether, Thomas, Korte, Martin, Heneka, Michael T.
Published in Neuron (Cambridge, Mass.) (08.09.2011)
Published in Neuron (Cambridge, Mass.) (08.09.2011)
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Journal Article
Microglial PD‐1 stimulation by astrocytic PD‐L1 suppresses neuroinflammation and Alzheimer’s disease pathology
Kummer, Markus P, Ising, Christina, Kummer, Christiane, Sarlus, Heela, Griep, Angelika, Vieira‐Saecker, Ana, Schwartz, Stephanie, Halle, Annett, Brückner, Matthias, Händler, Kristian, Schultze, Joachim L, Beyer, Marc, Latz, Eicke, Heneka, Michael T
Published in The EMBO journal (15.12.2021)
Published in The EMBO journal (15.12.2021)
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Journal Article
Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease
Mildner, Alexander, Schlevogt, Bernhard, Kierdorf, Katrin, Böttcher, Chotima, Erny, Daniel, Kummer, Markus P, Quinn, Michael, Brück, Wolfgang, Bechmann, Ingo, Heneka, Michael T, Priller, Josef, Prinz, Marco
Published in The Journal of neuroscience (03.08.2011)
Published in The Journal of neuroscience (03.08.2011)
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Journal Article
Sepsis causes neuroinflammation and concomitant decrease of cerebral metabolism
Semmler, Alexander, Hermann, Sven, Mormann, Florian, Weberpals, Marc, Paxian, Stephan A, Okulla, Thorsten, Schäfers, Michael, Kummer, Markus P, Klockgether, Thomas, Heneka, Michael T
Published in Journal of neuroinflammation (15.09.2008)
Published in Journal of neuroinflammation (15.09.2008)
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Journal Article
Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine
Heneka, Michael T, Nadrigny, Fabian, Regen, Tommy, Martinez-Hernandez, Ana, Dumitrescu-Ozimek, Lucia, Terwel, Dick, Jardanhazi-Kurutz, Daniel, Walter, Jochen, Kirchhoff, Frank, Hanisch, Uwe-Karsten, Kummer, Markus P
Published in Proceedings of the National Academy of Sciences - PNAS (30.03.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (30.03.2010)
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Journal Article
CXCR3 promotes plaque formation and behavioral deficits in an Alzheimer's disease model
Krauthausen, Marius, Kummer, Markus P, Zimmermann, Julian, Reyes-Irisarri, Elisabet, Terwel, Dick, Bulic, Bruno, Heneka, Michael T, Müller, Marcus
Published in The Journal of clinical investigation (01.01.2015)
Published in The Journal of clinical investigation (01.01.2015)
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Journal Article
Impact and Therapeutic Potential of PPARs in Alzheimers Disease
Heneka, Michael T, Reyes-Irisarri, Elisabet, Hüll, Michael, Kummer, Markus P
Published in Current neuropharmacology (01.12.2011)
Published in Current neuropharmacology (01.12.2011)
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Journal Article
SFRP1 modulates astrocyte-to-microglia crosstalk in acute and chronic neuroinflammation
Rueda-Carrasco, Javier, Martin-Bermejo, María Jesús, Pereyra, Guadalupe, Mateo, María Inés, Borroto, Aldo, Brosseron, Frederic, Kummer, Markus P, Schwartz, Stephanie, López-Atalaya, José P, Alarcon, Balbino, Esteve, Pilar, Heneka, Michael T, Bovolenta, Paola
Published in EMBO reports (04.11.2021)
Published in EMBO reports (04.11.2021)
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Journal Article
Characterization and clinical use of inflammatory cerebrospinal fluid protein markers in Alzheimer's disease
Brosseron, Frederic, Traschütz, Andreas, Widmann, Catherine N, Kummer, Markus P, Tacik, Pawel, Santarelli, Francesco, Jessen, Frank, Heneka, Michael T
Published in Alzheimer's research & therapy (26.02.2018)
Published in Alzheimer's research & therapy (26.02.2018)
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Journal Article
Selective Loss of Noradrenaline Exacerbates Early Cognitive Dysfunction and Synaptic Deficits in APP/PS1 Mice
Hammerschmidt, Thea, Kummer, Markus P, Terwel, Dick, Martinez, Ana, Gorji, Ali, Pape, Hans-Christian, Rommelfanger, Karen S, Schroeder, Jason P, Stoll, Monika, Schultze, Joachim, Weinshenker, David, Heneka, Michael T
Published in Biological psychiatry (1969) (01.03.2013)
Published in Biological psychiatry (1969) (01.03.2013)
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Journal Article
Postoperative Ileus Involves Interleukin-1 Receptor Signaling in Enteric Glia
Stoffels, Burkhard, Hupa, Kristof Johannes, Snoek, Susanne A, van Bree, Sjoerd, Stein, Kathy, Schwandt, Timo, Vilz, Tim O, Lysson, Mariola, Veer, Cornelis van't, Kummer, Markus P, Hornung, Veit, Kalff, Joerg C, de Jonge, Wouter J, Wehner, Sven
Published in Gastroenterology (New York, N.Y. 1943) (2014)
Published in Gastroenterology (New York, N.Y. 1943) (2014)
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Journal Article
Mrp14 deficiency ameliorates amyloid β burden by increasing microglial phagocytosis and modulation of amyloid precursor protein processing
Kummer, Markus P, Vogl, Thomas, Axt, Daisy, Griep, Angelika, Vieira-Saecker, Ana, Jessen, Frank, Gelpi, Ellen, Roth, Johannes, Heneka, Michael T
Published in The Journal of neuroscience (05.12.2012)
Published in The Journal of neuroscience (05.12.2012)
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Journal Article