Redox-sensitive alteration of replisome architecture safeguards genome integrity
Somyajit, Kumar, Gupta, Rajat, Sedlackova, Hana, Neelsen, Kai John, Ochs, Fena, Rask, Maj-Britt, Choudhary, Chunaram, Lukas, Jiri
Published in Science (American Association for the Advancement of Science) (10.11.2017)
Published in Science (American Association for the Advancement of Science) (10.11.2017)
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Journal Article
DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity
Gupta, Rajat, Somyajit, Kumar, Narita, Takeo, Maskey, Elina, Stanlie, Andre, Kremer, Magdalena, Typas, Dimitris, Lammers, Michael, Mailand, Niels, Nussenzweig, Andre, Lukas, Jiri, Choudhary, Chunaram
Published in Cell (03.05.2018)
Published in Cell (03.05.2018)
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Journal Article
Mammalian RAD51 paralogs protect nascent DNA at stalled forks and mediate replication restart
Somyajit, Kumar, Saxena, Sneha, Babu, Sharath, Mishra, Anup, Nagaraju, Ganesh
Published in Nucleic acids research (16.11.2015)
Published in Nucleic acids research (16.11.2015)
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Journal Article
Homologous Recombination as a Fundamental Genome Surveillance Mechanism during DNA Replication
Spies, Julian, Polasek-Sedlackova, Hana, Lukas, Jiri, Somyajit, Kumar
Published in Genes (09.12.2021)
Published in Genes (09.12.2021)
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Journal Article
Homology-directed repair protects the replicating genome from metabolic assaults
Somyajit, Kumar, Spies, Julian, Coscia, Fabian, Kirik, Ufuk, Rask, Maj-Britt, Lee, Ji-Hoon, Neelsen, Kai John, Mund, Andreas, Jensen, Lars Juhl, Paull, Tanya T., Mann, Matthias, Lukas, Jiri
Published in Developmental cell (22.02.2021)
Published in Developmental cell (22.02.2021)
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Journal Article
Physiological Tolerance to ssDNA Enables Strand Uncoupling during DNA Replication
Ercilla, Amaia, Benada, Jan, Amitash, Sampath, Zonderland, Gijs, Baldi, Giorgio, Somyajit, Kumar, Ochs, Fena, Costanzo, Vincenzo, Lukas, Jiri, Toledo, Luis
Published in Cell reports (Cambridge) (18.02.2020)
Published in Cell reports (Cambridge) (18.02.2020)
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Journal Article
53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication
Leriche, Melissa, Bonnet, Clara, Jana, Jagannath, Chhetri, Gita, Mennour, Sabrina, Martineau, Sylvain, Pennaneach, Vincent, Busso, Didier, Veaute, Xavier, Bertrand, Pascale, Lambert, Sarah, Somyajit, Kumar, Uguen, Patricia, Vagner, Stéphan
Published in Cell reports (Cambridge) (28.11.2023)
Published in Cell reports (Cambridge) (28.11.2023)
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Journal Article
Methotrexate Promotes Platelet Apoptosis via JNK-Mediated Mitochondrial Damage: Alleviation by N-Acetylcysteine and N-Acetylcysteine Amide
Paul, Manoj, Hemshekhar, Mahadevappa, Thushara, Ram M, Sundaram, Mahalingam S, NaveenKumar, Somanathapura K, Naveen, Shivanna, Devaraja, Sannaningaiah, Somyajit, Kumar, West, Robert, Basappa, Nayaka, Siddaiah C, Zakai, Uzma I, Nagaraju, Ganesh, Rangappa, Kanchugarakoppal S, Kemparaju, Kempaiah, Girish, Kesturu S
Published in PloS one (17.06.2015)
Published in PloS one (17.06.2015)
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Journal Article
Propionate reinforces epithelial identity and reduces aggressiveness of lung carcinoma
Ramesh, Vignesh, Gollavilli, Paradesi Naidu, Pinna, Luisa, Siddiqui, Mohammad Aarif, Turtos, Adriana Martinez, Napoli, Francesca, Antonelli, Yasmin, Leal‐Egaña, Aldo, Havelund, Jesper Foged, Jakobsen, Simon Toftholm, Boiteux, Elisa Le, Volante, Marco, Færgeman, Nils Joakim, Jensen, Ole N, Siersbæk, Rasmus, Somyajit, Kumar, Ceppi, Paolo
Published in EMBO molecular medicine (07.12.2023)
Published in EMBO molecular medicine (07.12.2023)
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Journal Article
Equilibrium between nascent and parental MCM proteins protects replicating genomes
Sedlackova, Hana, Rask, Maj-Britt, Gupta, Rajat, Choudhary, Chunaram, Somyajit, Kumar, Lukas, Jiri
Published in Nature (London) (12.11.2020)
Published in Nature (London) (12.11.2020)
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Journal Article
Correction: Distinct roles of FANCO/RAD51C protein in DNA damage signaling and repair: Implications for Fanconi anemia and breast cancer susceptibility
Somyajit, Kumar, Subramanya, Shreelakshmi, Nagaraju, Ganesh
Published in The Journal of biological chemistry (30.08.2019)
Published in The Journal of biological chemistry (30.08.2019)
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Journal Article
Mammalian RAD51 paralogs protect nascent DNA at stalled forks and mediate replication restart
Somyajit, Kumar, Saxena, Sneha, Babu, Sharath, Mishra, Anup, Nagaraju, Ganesh
Published in Nucleic acids research (21.05.2020)
Published in Nucleic acids research (21.05.2020)
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Journal Article
RTEL1 helicase counteracts RAD51-mediated homologous recombination and fork reversal to safeguard replicating genomes
Dixit, Suruchi, Nagraj, Tarun, Bhattacharya, Debanjali, Saxena, Sneha, Sahoo, Satyaranjan, Chittela, Rajani Kant, Somyajit, Kumar, Nagaraju, Ganesh
Published in Cell reports (Cambridge) (27.08.2024)
Published in Cell reports (Cambridge) (27.08.2024)
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Journal Article