Evaluating the Substrate-Envelope Hypothesis: Structural Analysis of Novel HIV-1 Protease Inhibitors Designed To Be Robust against Drug Resistance
NALAM, Madhavi N. L, ALI, Akbar, RANA, Tariq M, SCHIFFER, Celia A, ALTMAN, Michael D, KIRAN KUMAR REDDY, G. S, CHELLAPPAN, Sripriya, KAIRYS, Visvaldas, ZEN, Ayşegül Ö, HONG CAO, GILSON, Michael K, TIDOR, Bruce
Published in Journal of Virology (01.05.2010)
Published in Journal of Virology (01.05.2010)
Get full text
Journal Article
Design and Synthesis of HIV-1 Protease Inhibitors Incorporating Oxazolidinones as P2/P2‘ Ligands in Pseudosymmetric Dipeptide Isosteres
Reddy, G. S. Kiran Kumar, Ali, Akbar, Nalam, Madhavi N. L, Anjum, Saima Ghafoor, Cao, Hong, Nathans, Robin S, Schiffer, Celia A, Rana, Tariq M
Published in Journal of medicinal chemistry (06.09.2007)
Published in Journal of medicinal chemistry (06.09.2007)
Get full text
Journal Article
Efficient Computation of Small-Molecule Configurational Binding Entropy and Free Energy Changes by Ensemble Enumeration
Silver, Nathaniel W, King, Bracken M, Nalam, Madhavi N. L, Cao, Hong, Ali, Akbar, Kiran Kumar Reddy, G. S, Rana, Tariq M, Schiffer, Celia A, Tidor, Bruce
Published in Journal of chemical theory and computation (12.11.2013)
Published in Journal of chemical theory and computation (12.11.2013)
Get full text
Journal Article
Additivity in the Analysis and Design of HIV Protease Inhibitors
Jorissen, Robert N, Reddy, G. S. Kiran Kumar, Ali, Akbar, Altman, Michael D, Chellappan, Sripriya, Anjum, Saima G, Tidor, Bruce, Schiffer, Celia A, Rana, Tariq M, Gilson, Michael K
Published in Journal of medicinal chemistry (12.02.2009)
Published in Journal of medicinal chemistry (12.02.2009)
Get full text
Journal Article
Design of Mutation-resistant HIV Protease Inhibitors with the Substrate Envelope Hypothesis
Chellappan, Sripriya, Kiran Kumar Reddy, G. S., Ali, Akbar, Nalam, Madhavi N. L., Anjum, Saima Ghafoor, Cao, Hong, Kairys, Visvaldas, Fernandes, Miguel X., Altman, Michael D., Tidor, Bruce, Rana, Tariq M., Schiffer, Celia A., Gilson, Michael K.
Published in Chemical biology & drug design (01.05.2007)
Published in Chemical biology & drug design (01.05.2007)
Get full text
Journal Article
Structure-Based Design, Synthesis, and Structure−Activity Relationship Studies of HIV-1 Protease Inhibitors Incorporating Phenyloxazolidinones
Ali, Akbar, Reddy, G. S. Kiran Kumar, Nalam, Madhavi N. L, Anjum, Saima Ghafoor, Cao, Hong, Schiffer, Celia A, Rana, Tariq M
Published in Journal of medicinal chemistry (11.11.2010)
Published in Journal of medicinal chemistry (11.11.2010)
Get full text
Journal Article
HIV-1 Protease Inhibitors from Inverse Design in the Substrate Envelope Exhibit Subnanomolar Binding to Drug-Resistant Variants
Altman, Michael D, Ali, Akbar, Kumar Reddy, G. S. Kiran, Nalam, Madhavi N. L, Anjum, Saima Ghafoor, Cao, Hong, Chellappan, Sripriya, Kairys, Visvaldas, Fernandes, Miguel X, Gilson, Michael K, Schiffer, Celia A, Rana, Tariq M, Tidor, Bruce
Published in Journal of the American Chemical Society (14.05.2008)
Published in Journal of the American Chemical Society (14.05.2008)
Get full text
Journal Article
Discovery of HIV-1 Protease Inhibitors with Picomolar Affinities Incorporating N-Aryl-oxazolidinone-5-carboxamides as Novel P2 Ligands
Ali, Akbar, Reddy, G. S. Kiran Kumar, Cao, Hong, Anjum, Saima Ghafoor, Nalam, Madhavi N. L, Schiffer, Celia A, Rana, Tariq M
Published in Journal of medicinal chemistry (14.12.2006)
Published in Journal of medicinal chemistry (14.12.2006)
Get full text
Journal Article
Luciferin Amides Enable in Vivo Bioluminescence Detection of Endogenous Fatty Acid Amide Hydrolase Activity
Mofford, David M, Adams, Spencer T, Reddy, G. S. Kiran Kumar, Reddy, Gadarla Randheer, Miller, Stephen C
Published in Journal of the American Chemical Society (15.07.2015)
Published in Journal of the American Chemical Society (15.07.2015)
Get full text
Journal Article
A New, Efficient and Environmentally Benign Protocol for the Synthesis of 1,5-Benzodiazepines using Cerium(III) Chloride/Sodium Iodide Supported on Silica Gel
Sabitha, Gowravaram, Reddy, G. S. Kiran Kumar, Reddy, K. Bhaskar, Reddy, N. Mallikarjuna, Yadav, J. S.
Published in Advanced synthesis & catalysis (01.07.2004)
Published in Advanced synthesis & catalysis (01.07.2004)
Get full text
Journal Article
Substrate Envelope-Designed Potent HIV-1 Protease Inhibitors to Avoid Drug Resistance
Nalam, Madhavi N.L., Ali, Akbar, Reddy, G.S. Kiran Kumar, Cao, Hong, Anjum, Saima G., Altman, Michael D., Yilmaz, Nese Kurt, Tidor, Bruce, Rana, Tariq M., Schiffer, Celia A.
Published in Chemistry & biology (19.09.2013)
Published in Chemistry & biology (19.09.2013)
Get full text
Journal Article
Vanadium(III) chloride: A mild and efficient catalyst for the chemoselective deprotection of acetonides
Sabitha, Gowravaram, Reddy, G.S. Kiran Kumar, Reddy, K. Bhaskar, Reddy, N. Mallikarjuna, Yadav, J.S.
Published in Journal of molecular catalysis. A, Chemical (01.09.2005)
Published in Journal of molecular catalysis. A, Chemical (01.09.2005)
Get full text
Journal Article
INDIUM-MEDIATED BARBIER REACTIONS OF AZIDES: A FACILE SYNTHESIS OF N-ALLYLAMINE DERIVATIVES
Yadav, J. S., Madhuri, Ch, Reddy, B. V. S., Kiran Kumar Reddy, G. S., Sabitha, G.
Published in Synthetic communications (01.01.2002)
Published in Synthetic communications (01.01.2002)
Get full text
Journal Article
TMSI-Mediated Prins Cyclization: Diastereoselective Synthesis of 4-Iodo-2,6-Disubstituted Tetrahydropyrans and Synthesis of (.+-.)-Centrolobine
Sabitha, Gowravaram, Reddy, K. Bhaskar, Reddy, G. S. Kiran Kumar, Fatima, Narjis, Yadav, J. S.
Published in ChemInform (31.01.2006)
Published in ChemInform (31.01.2006)
Get full text
Journal Article
Vanadium(III) Chloride Catalyzed Preparation of β-Amino Alcohols from Epoxides
Sabitha, Gowravaram, Reddy, G. S. Kiran Kumar, Reddy, K. Bhaskar, Yadav, J. S.
Published in ChemInform (16.03.2004)
Published in ChemInform (16.03.2004)
Get full text
Journal Article