METTL3 Inhibitors for Epitranscriptomic Modulation of Cellular Processes
Moroz‐Omori, Elena V., Huang, Danzhi, Kumar Bedi, Rajiv, Cheriyamkunnel, Sherry J., Bochenkova, Elena, Dolbois, Aymeric, Rzeczkowski, Maciej D., Li, Yaozong, Wiedmer, Lars, Caflisch, Amedeo
Published in ChemMedChem (06.10.2021)
Published in ChemMedChem (06.10.2021)
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Journal Article
The catalytic mechanism of the RNA methyltransferase METTL3
Corbeski, Ivan, Vargas-Rosales, Pablo Andrés, Bedi, Rajiv Kumar, Deng, Jiahua, Coelho, Dylan, Braud, Emmanuelle, Iannazzo, Laura, Li, Yaozong, Huang, Danzhi, Ethève-Quelquejeu, Mélanie, Cui, Qiang, Caflisch, Amedeo
Published in eLife (12.03.2024)
Published in eLife (12.03.2024)
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Journal Article
Structure-based design of ligands of the m6A-RNA reader YTHDC1
Li, Yaozong, Bedi, Rajiv Kumar, Nai, Francesco, von Roten, Valentin, Dolbois, Aymeric, Zálešák, František, Nachawati, Raed, Huang, Danzhi, Caflisch, Amedeo
Published in European journal of medicinal chemistry reports (01.08.2022)
Published in European journal of medicinal chemistry reports (01.08.2022)
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Journal Article
Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m6A) Recognition by the Reader Domain of YTHDC1
Li, Yaozong, Bedi, Rajiv Kumar, Wiedmer, Lars, Sun, Xianqiang, Huang, Danzhi, Caflisch, Amedeo
Published in Journal of chemical theory and computation (09.02.2021)
Published in Journal of chemical theory and computation (09.02.2021)
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Journal Article
Structure-Based Design of Inhibitors of the m6A‑RNA Writer Enzyme METTL3
Bedi, Rajiv Kumar, Huang, Danzhi, Li, Yaozong, Caflisch, Amedeo
Published in ACS bio & med chem au (16.08.2023)
Published in ACS bio & med chem au (16.08.2023)
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Journal Article
Flexible Binding of m6A Reader Protein YTHDC1 to Its Preferred RNA Motif
Li, Yaozong, Bedi, Rajiv Kumar, Wiedmer, Lars, Huang, Danzhi, Śledź, Paweł, Caflisch, Amedeo
Published in Journal of chemical theory and computation (10.12.2019)
Published in Journal of chemical theory and computation (10.12.2019)
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Journal Article
Structure-Based Design of Inhibitors of the m 6 A-RNA Writer Enzyme METTL3
Bedi, Rajiv Kumar, Huang, Danzhi, Li, Yaozong, Caflisch, Amedeo
Published in ACS bio & med chem au (16.08.2023)
Published in ACS bio & med chem au (16.08.2023)
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Journal Article
Flexible Binding of m 6 A Reader Protein YTHDC1 to Its Preferred RNA Motif
Li, Yaozong, Bedi, Rajiv Kumar, Wiedmer, Lars, Huang, Danzhi, Śledź, Paweł, Caflisch, Amedeo
Published in Journal of chemical theory and computation (10.12.2019)
Published in Journal of chemical theory and computation (10.12.2019)
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Journal Article
A Reader-Based Assay for m 6 A Writers and Erasers
Wiedmer, Lars, Eberle, Stefanie Alexandra, Bedi, Rajiv Kumar, Śledź, Paweł, Caflisch, Amedeo
Published in Analytical chemistry (Washington) (19.02.2019)
Published in Analytical chemistry (Washington) (19.02.2019)
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Journal Article
A Reader-Based Assay for m6A Writers and Erasers
Wiedmer, Lars, Eberle, Stefanie Alexandra, Bedi, Rajiv Kumar, Śledź, Paweł, Caflisch, Amedeo
Published in Analytical chemistry (Washington) (19.02.2019)
Published in Analytical chemistry (Washington) (19.02.2019)
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Journal Article
The catalytic mechanism of the RNA methyltransferase METTL3
Corbeski, Ivan, Vargas-Rosales, Pablo Andrés, Bedi, Rajiv Kumar, Deng, Jiahua, Coelho, Dylan, Braud, Emmanuelle, Iannazzo, Laura, Li, Yaozong, Huang, Danzhi, Ethève-Quelquejeu, Mélanie, Cui, Qiang, Caflisch, Amedeo
Published in eLife (12.03.2024)
Published in eLife (12.03.2024)
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Journal Article
Selectively Disrupting m6A‑Dependent Protein–RNA Interactions with Fragments
Bedi, Rajiv Kumar, Huang, Danzhi, Wiedmer, Lars, Li, Yaozong, Dolbois, Aymeric, Wojdyla, Justyna Aleksandra, Sharpe, May Elizabeth, Caflisch, Amedeo, Sledz, Pawel
Published in ACS chemical biology (20.03.2020)
Published in ACS chemical biology (20.03.2020)
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Journal Article
Selectively Disrupting m 6 A-Dependent Protein-RNA Interactions with Fragments
Bedi, Rajiv Kumar, Huang, Danzhi, Wiedmer, Lars, Li, Yaozong, Dolbois, Aymeric, Wojdyla, Justyna Aleksandra, Sharpe, May Elizabeth, Caflisch, Amedeo, Sledz, Pawel
Published in ACS chemical biology (20.03.2020)
Published in ACS chemical biology (20.03.2020)
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Journal Article
Structure-based design of ligands of the m 6 A-RNA reader YTHDC1
Li, Yaozong, Bedi, Rajiv Kumar, Nai, Francesco, von Roten, Valentin, Dolbois, Aymeric, Zálešák, František, Nachawati, Raed, Huang, Danzhi, Caflisch, Amedeo
Published in European journal of medicinal chemistry reports (2022)
Published in European journal of medicinal chemistry reports (2022)
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Journal Article
The catalytic mechanism of the RNA methyltransferase METTL3
Corbeski, Ivan, Vargas-Rosales, Pablo Andres, Bedi, Rajiv Kumar, Deng, Jiahua, Coelho, Dylan, Braud, Emmanuelle, Iannazzo, Laura, Li, Yaozong, Huang, Danzhi, Etheve-Quelquejeu, Melanie, Cui, Qiang, Caflisch, Amedeo
Published in bioRxiv : the preprint server for biology (21.12.2023)
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Published in bioRxiv : the preprint server for biology (21.12.2023)
Journal Article
Design and implementation of enhanced MQS algorithm
Kaur, Gurmeet, Bedi, Rajiv Kumar, Gupta, S. K.
Published in 2015 International Conference on Green Computing and Internet of Things (ICGCIoT) (01.10.2015)
Published in 2015 International Conference on Green Computing and Internet of Things (ICGCIoT) (01.10.2015)
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Conference Proceeding
Flexible binding of m6A reader protein YTHDC1 to its preferred RNA motif
Li, Yaozong, Bedi, Rajiv Kumar, Wiedmer, Lars, Huang, Danzhi, Śledź, Paweł, Caflisch, Amedeo
Published in bioRxiv (30.09.2019)
Published in bioRxiv (30.09.2019)
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Paper
METTL3 inhibitors for epitranscriptomic modulation of cellular processes
Moroz-Omori, Elena V, Huang, Danzhi, Bedi, Rajiv Kumar, Cheriyamkunnel, Sherry J, Bochenkova, Elena, Dolbois, Aymeric, Rzeczkowski, Maciej D, Wiedmer, Lars, Caflisch, Amedeo
Published in bioRxiv (13.10.2020)
Published in bioRxiv (13.10.2020)
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Paper