Human Secreted Ly-6/uPAR Related Protein-1 (SLURP-1) Is a Selective Allosteric Antagonist of α7 Nicotinic Acetylcholine Receptor
Lyukmanova, Ekaterina N, Shulepko, Mikhail A, Kudryavtsev, Denis, Bychkov, Maxim L, Kulbatskii, Dmitrii S, Kasheverov, Igor E, Astapova, Maria V, Feofanov, Alexey V, Thomsen, Morten S, Mikkelsen, Jens D, Shenkarev, Zakhar O, Tsetlin, Victor I, Dolgikh, Dmitry A, Kirpichnikov, Mikhail P
Published in PloS one (23.02.2016)
Published in PloS one (23.02.2016)
Get full text
Journal Article
Structural Diversity and Dynamics of Human Three-Finger Proteins Acting on Nicotinic Acetylcholine Receptors
Paramonov, Alexander S, Kocharovskaya, Milita V, Tsarev, Andrey V, Kulbatskii, Dmitrii S, Loktyushov, Eugene V, Shulepko, Mikhail A, Kirpichnikov, Mikhail P, Lyukmanova, Ekaterina N, Shenkarev, Zakhar O
Published in International journal of molecular sciences (01.10.2020)
Published in International journal of molecular sciences (01.10.2020)
Get full text
Journal Article
Molecular Basis for Mambalgin-2 Interaction with Heterotrimeric α-ENaC/ASIC1a/γ-ENaC Channels in Cancer Cells
Lyukmanova, Ekaterina N, Zaigraev, Maxim M, Kulbatskii, Dmitrii S, Isaev, Aizek B, Kukushkin, Ilya D, Bychkov, Maxim L, Shulepko, Mikhail A, Chugunov, Anton O, Kirpichnikov, Mikhail P
Published in Toxins (01.10.2023)
Published in Toxins (01.10.2023)
Get full text
Journal Article
New Three-Finger Protein from Starfish Asteria rubens Shares Structure and Pharmacology with Human Brain Neuromodulator Lynx2
Paramonov, Alexander S., Shulepko, Mikhail A., Makhonin, Alexey M., Bychkov, Maxim L., Kulbatskii, Dmitrii S., Chernikov, Andrey M., Myshkin, Mikhail Yu, Shabelnikov, Sergey V., Shenkarev, Zakhar O., Kirpichnikov, Mikhail P., Lyukmanova, Ekaterina N.
Published in Marine drugs (03.08.2022)
Published in Marine drugs (03.08.2022)
Get full text
Journal Article
Mambalgin-2 Inhibits Lung Adenocarcinoma Growth and Migration by Selective Interaction With ASIC1/α-ENaC/γ-ENaC Heterotrimer
Sudarikova, Anastasia V., Bychkov, Maxim L., Kulbatskii, Dmitrii S., Chubinskiy-Nadezhdin, Vladislav I., Shlepova, Olga V., Shulepko, Mikhail A., Koshelev, Sergey G., Kirpichnikov, Mikhail P., Lyukmanova, Ekaterina N.
Published in Frontiers in oncology (28.06.2022)
Published in Frontiers in oncology (28.06.2022)
Get full text
Journal Article
Recombinant Production, NMR Solution Structure, and Membrane Interaction of the Phα1β Toxin, a TRPA1 Modulator from the Brazilian Armed Spider Phoneutria nigriventer
Lyukmanova, Ekaterina N, Mironov, Pavel A, Kulbatskii, Dmitrii S, Shulepko, Mikhail A, Paramonov, Alexander S, Chernaya, Elizaveta M, Logashina, Yulia A, Andreev, Yaroslav A, Kirpichnikov, Mikhail P, Shenkarev, Zakhar O
Published in Toxins (03.06.2023)
Published in Toxins (03.06.2023)
Get full text
Journal Article
Upregulation of cholinergic modulators Lypd6 and Lypd6b associated with autism drives anxiety and cognitive decline
Isaev, Aizek B., Bychkov, Maxim L., Kulbatskii, Dmitrii S., Andreev-Andrievskiy, Alexander A., Mashkin, Mikhail A., Shulepko, Mikhail A., Shlepova, Olga V., Loktyushov, Eugene V., Latanov, Alexander V., Kirpichnikov, Mikhail P., Lyukmanova, Ekaterina N.
Published in Cell death discovery (21.10.2024)
Published in Cell death discovery (21.10.2024)
Get full text
Journal Article
Membrane-mediated interaction of non-conventional snake three-finger toxins with nicotinic acetylcholine receptors
Shenkarev, Zakhar O., Chesnokov, Yuri M., Zaigraev, Maxim M., Chugunov, Anton O., Kulbatskii, Dmitrii S., Kocharovskaya, Milita V., Paramonov, Alexander S., Bychkov, Maxim L., Shulepko, Mikhail A., Nolde, Dmitry E., Kamyshinsky, Roman A., Yablokov, Evgeniy O., Ivanov, Alexey S., Kirpichnikov, Mikhail P., Lyukmanova, Ekaterina N.
Published in Communications biology (07.12.2022)
Published in Communications biology (07.12.2022)
Get full text
Journal Article
SLURP-1 Controls Growth and Migration of Lung Adenocarcinoma Cells, Forming a Complex With α7-nAChR and PDGFR/EGFR Heterodimer
Bychkov, Maxim L, Shulepko, Mikhail A, Shlepova, Olga V, Kulbatskii, Dmitrii S, Chulina, Irina A, Paramonov, Alexander S, Baidakova, Ludmila K, Azev, Viatcheslav N, Koshelev, Sergey G, Kirpichnikov, Mikhail P, Shenkarev, Zakhar O, Lyukmanova, Ekaterina N
Published in Frontiers in cell and developmental biology (14.09.2021)
Published in Frontiers in cell and developmental biology (14.09.2021)
Get full text
Journal Article
Cell-Free Expression of Sodium Channel Domains for Pharmacology Studies. Noncanonical Spider Toxin Binding Site in the Second Voltage-Sensing Domain of Human Nav1.4 Channel
Myshkin, Mikhail Yu, Männikkö, Roope, Krumkacheva, Olesya A., Kulbatskii, Dmitrii S., Chugunov, Anton O., Berkut, Antonina A., Paramonov, Alexander S., Shulepko, Mikhail A., Fedin, Matvey V., Hanna, Michael G., Kullmann, Dimitri M., Bagryanskaya, Elena G., Arseniev, Alexander S., Kirpichnikov, Mikhail P., Lyukmanova, Ekaterina N., Vassilevski, Alexander A., Shenkarev, Zakhar O.
Published in Frontiers in pharmacology (04.09.2019)
Published in Frontiers in pharmacology (04.09.2019)
Get full text
Journal Article
Engineering of Chimeric Protein Based on E Protein Domain III of Tick- Borne Encephalitis Virus and OmpF Porin of Yersinia pseudotuberculosis
Stenkova, Anna M, Chopenko, Natalia S, Davydova, Ludmila A, Mazeika, Andrey N, Bystritskaya, Evgeniya P, Portnyagina, Olga Y, Anastyuk, Stanislav D, Kulbatskii, Dmitrii S, Lyukmanova, Ekaterina N, Dolgikh, Dmitriy A, Kostetsky, Eduard Y, Sanina, Nina M
Published in Protein and peptide letters (01.01.2017)
Published in Protein and peptide letters (01.01.2017)
Get more information
Journal Article
Crystal structure reveals canonical recognition of the phosphorylated cytoplasmic loop of human alpha7 nicotinic acetylcholine receptor by 14-3-3 protein
Sluchanko, Nikolai N., Kapitonova, Anna A., Shulepko, Mikhail A., Kukushkin, Ilya D., Kulbatskii, Dmitrii S., Tugaeva, Kristina V., Varfolomeeva, Larisa A., Minyaev, Mikhail E., Boyko, Konstantin M., Popov, Vladimir O., Kirpichnikov, Mikhail P., Lyukmanova, Ekaterina N.
Published in Biochemical and biophysical research communications (19.11.2023)
Published in Biochemical and biophysical research communications (19.11.2023)
Get full text
Journal Article
Biochemical Basis of Skin Disease Mal de Meleda: SLURP-1 Mutants Differently Affect Keratinocyte Proliferation and Apoptosis
Shulepko, Mikhail A., Bychkov, Maxim L., Shenkarev, Zakhar O., Kulbatskii, Dmitrii S., Makhonin, Alexey M., Paramonov, Alexander S., Chugunov, Anton O., Kirpichnikov, Mikhail P., Lyukmanova, Ekaterina N.
Published in Journal of investigative dermatology (01.09.2021)
Published in Journal of investigative dermatology (01.09.2021)
Get full text
Journal Article
Water‐soluble variant of human Lynx1 positively modulates synaptic plasticity and ameliorates cognitive impairment associated with α7‐nAChR dysfunction
Shenkarev, Zakhar O., Shulepko, Mikhail A., Bychkov, Maxim L., Kulbatskii, Dmitrii S., Shlepova, Olga V., Vasilyeva, Nathalia A., Andreev-Andrievskiy, Alexander A., Popova, Anfisa S., Lagereva, Evgeniya A., Loktyushov, Eugene V., Koshelev, Sergey G., Thomsen, Morten S., Dolgikh, Dmitry A., Kozlov, Sergey A., Balaban, Pavel M., Kirpichnikov, Mikhail P., Lyukmanova, Ekaterina N.
Published in Journal of neurochemistry (01.10.2020)
Published in Journal of neurochemistry (01.10.2020)
Get full text
Journal Article
Spider toxin inhibits gating pore currents underlying periodic paralysis
Männikkö, Roope, Shenkarev, Zakhar O., Thor, Michael G., Berkut, Antonina A., Myshkin, Mikhail Yu, Paramonov, Alexander S., Kulbatskii, Dmitrii S., Kuzmin, Dmitry A., Castañeda, Marisol Sampedro, King, Louise, Wilson, Emma R., Lyukmanova, Ekaterina N., Kirpichnikov, Mikhail P., Schorge, Stephanie, Bosmans, Frank, Hanna, Michael G., Kullmann, Dimitri M., Vassilevski, Alexander A.
Published in Proceedings of the National Academy of Sciences - PNAS (24.04.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (24.04.2018)
Get full text
Journal Article
Central loop of non-conventional toxin WTX from Naja kaouthia is important for interaction with nicotinic acetylcholine receptors
Lyukmanova, Ekaterina N., Shulepko, Mikhail A., Shenkarev, Zakhar O., Kasheverov, Igor E., Chugunov, Anton O., Kulbatskii, Dmitrii S., Myshkin, Mikhail Yu, Utkin, Yuri N., Efremov, Roman G., Tsetlin, Victor I., Arseniev, Alexander S., Kirpichnikov, Mikhail P., Dolgikh, Dmitry A.
Published in Toxicon (Oxford) (01.09.2016)
Published in Toxicon (Oxford) (01.09.2016)
Get full text
Journal Article
Cell-Free Expression of Sodium Channel Domains for Pharmacology Studies. Noncanonical Spider Toxin Binding Site in the Second Voltage-Sensing Domain of Human Na v 1.4 Channel
Myshkin, Mikhail Yu, Männikkö, Roope, Krumkacheva, Olesya A, Kulbatskii, Dmitrii S, Chugunov, Anton O, Berkut, Antonina A, Paramonov, Alexander S, Shulepko, Mikhail A, Fedin, Matvey V, Hanna, Michael G, Kullmann, Dimitri M, Bagryanskaya, Elena G, Arseniev, Alexander S, Kirpichnikov, Mikhail P, Lyukmanova, Ekaterina N, Vassilevski, Alexander A, Shenkarev, Zakhar O
Published in Frontiers in pharmacology (04.09.2019)
Published in Frontiers in pharmacology (04.09.2019)
Get full text
Journal Article
In Search of the Role of Three-Finger Starfish Proteins
Lyukmanova, Ekaterina N., Bychkov, Maxim L., Chernikov, Andrei M., Kukushkin, Ilya D., Kulbatskii, Dmitrii S., Shabelnikov, Sergey V., Shulepko, Mikhail A., Zhao, Ran, Guo, Wenxiao, Kirpichnikov, Mikhail P., Shenkarev, Zakhar O., Paramonov, Alexander S.
Published in Marine drugs (30.10.2024)
Published in Marine drugs (30.10.2024)
Get full text
Journal Article
Recombinant Production, NMR Solution Structure, and Membrane Interaction of the Phα1β Toxin, a TRPA1 Modulator from the Brazilian Armed Spider IPhoneutria nigriventer/I
Lyukmanova, Ekaterina N, Mironov, Pavel A, Kulbatskii, Dmitrii S, Shulepko, Mikhail A, Paramonov, Alexander S, Chernaya, Elizaveta M, Logashina, Yulia A, Andreev, Yaroslav A, Kirpichnikov, Mikhail P, Shenkarev, Zakhar O
Published in Toxins (01.06.2023)
Published in Toxins (01.06.2023)
Get full text
Journal Article
Human Secreted Ly-6/uPAR Related Protein-1 (SLURP-1) Is a Selective Allosteric Antagonist of [alpha]7 Nicotinic Acetylcholine Receptor
Lyukmanova, Ekaterina N, Shulepko, Mikhail A, Kudryavtsev, Denis, Bychkov, Maxim L, Kulbatskii, Dmitrii S, Kasheverov, Igor E, Astapova, Maria V, Feofanov, Alexey V, Thomsen, Morten S, Mikkelsen, Jens D, Shenkarev, Zakhar O, Tsetlin, Victor I, Dolgikh, Dmitry A, Kirpichnikov, Mikhail P
Published in PloS one (23.02.2016)
Published in PloS one (23.02.2016)
Get full text
Journal Article